Reducing Mobile Storage Writes : Non-Volatile Write Buffer and PRAM-based Journaling

Sungjoo Yoo(유승주),Mungyu Son(손문규),Sungkwang Lee(이성광),Taemin Lee(이태민),Hyunsun Park(박현선),Sunggu Lee(이승구) 한국정보과학회 2015 정보과학회지 Vol.33 No.2

Active Memory Processor for Network-on-Chip-Based Architecture

Junhee Yoo,Sungjoo Yoo,Kiyoung Choi IEEE 2012 IEEE TRANSACTIONS ON COMPUTERS - Vol.61 No.5

<P>Memory-intensive operations and their memory access latency are often the performance bottleneck in parallel applications. In this paper, we investigate the concept of active memory operation which is an active data processing operation performed on the memory side. Utilizing the active memory operation, we can replace multiple transactions of memory accesses over the on-chip network and related computations on the processor side with a smaller number of high-level transactions and computations on the memory side. To realize the concept, we have designed a special-purpose processor called active memory processor which is tightly coupled with the memory and executes the active memory operations. In our case studies, we have applied the concept to five real-world applications (parallelized JPEG, FFT, text indexing for data mining, histogram, and eikonal equation solver) running on a 36--tile architecture with 64 cores and four memory tiles and found that the proposed approach can improve performance by 20.5~ 259.3 percent.</P>

Topology/Floorplan/Pipeline Co-Design of Cascaded Crossbar Bus

Junhee Yoo,Sungjoo Yoo,Kiyoung Choi IEEE 2009 IEEE transactions on very large scale integration Vol.17 No.8

<P>On-chip bus design has a significant impact on the die area, power consumption, performance and design cycle of complex system-on-chips (SoCs). Especially, for high frequency systems having on-chip buses pipelined extensively to cope with long wire delay, a naive bus design may yield a significant area/power cost mostly due to bus pipeline cost. The topology, floorplan, and pipeline are the most important design factors that affect the cost and frequency of the on-chip bus. Since they are strongly correlated with each other, it is imperative to codesign all of the three. In this paper, we present an automated codesign method for cascaded crossbar bus design. We present CADBUS (CAscadeD crossbar BUS design tool), an automated tool for AXI-based cascaded crossbar bus architecture design. The primary objective of this study is to design a cascaded crossbar bus, including the topology/floorplan/bus pipelines, having minimum area/power cost while satisfying the given constraints of communication bandwidth/latency or frequency. Experimental results of the three industrial strength SoCs show that, compared to the existing approach, the proposed method gives as much as 11.6%-34.2% (9.9%-33.5%) savings in bus area (power consumption).</P>

The Prevalence and Characteristics of Anemia after Intensive Care with a Restrictive Transfusion Strategy

Sungjoo Park(박성주),Chi-Min Park,Kyoung Won Yoon,Eunmi Gil,Keesang Yoo,Kyoung Jin Choi 대한외과학회 2021 대한외과학회 학술대회 초록집 Vol.2021 No.5

The E3 ubiquitin ligase MARCH2 regulates ERGIC3-dependent trafficking of secretory proteins

Yoo, Wonjin,Cho, Eun-Bee,Kim, Sungjoo,Yoon, Jong-Bok American Society for Biochemistry and Molecular Bi 2019 The Journal of biological chemistry Vol.294 No.28

<P>The E3 ubiquitin ligase membrane-associated ring-CH–type finger 2 (MARCH2) is known to be involved in intracellular vesicular trafficking, but its role in the early secretory pathway between the endoplasmic reticulum (ER) and Golgi compartments is largely unknown. Human ER–Golgi intermediate compartment protein 2 (ERGIC2) and ERGIC3 are orthologs of Erv41 and Erv46 in yeast, proteins that form a heteromeric complex, cycle between the ER and Golgi, and function as cargo receptors in both anterograde and retrograde protein trafficking. Here, we report that MARCH2 directs ubiquitination and subsequent degradation of ERGIC3 and that MARCH2 depletion increases endogenous ERGIC3 levels. We provide evidence that the lysine residues at positions 6 and 8 of ERGIC3 are the major sites of MARCH2-mediated ubiquitination. Of note, MARCH2 did not significantly decrease the levels of an ERGIC3 variant with lysine-to-arginine substitutions at residues 6 and 8. We also show that ERGIC3 binds to itself or to ERGIC2, whereas ERGIC2 is unable to interact with itself. Our results indicate that α<SUB>1</SUB>-antitrypsin and haptoglobin are likely to be cargo proteins of ERGIC3. We further observed that α<SUB>1</SUB>-antitrypsin and haptoglobin specifically bind to ERGIC3 and that ERGIC3 depletion decreases their secretion. Moreover, MARCH2 reduced secretion of α<SUB>1</SUB>-antitrypsin and haptoglobin, and coexpression of the ubiquitination-resistant ERGIC3 variant largely restored their secretion, suggesting that MARCH2-mediated ERGIC3 ubiquitination is the major cause of the decrease in trafficking of ERGIC3-binding secretory proteins. Our findings provide detailed insights into the regulation of the early secretory pathway by MARCH2 and into ERGIC3 function.</P>

MicroRNA-330-5p negatively regulates ITGA5 expression in human colorectal cancer

Yoo, Hye-In,Kim, Bong-Kyu,Yoon, Sungjoo Kim Spandidos Publications 2016 ONCOLOGY REPORTS Vol.36 No.5

<P>Colorectal cancer (CRC), one of the most prevalent malignant cancers, has high rates pf incidence and is the fourth leading cause of cancer-related deaths for both men and women worldwide. MicroRNAs (miRNAs) play critical roles in the development of various types of cancers. miRNA-330-5p has been implicated in the progression of prostate, neuronal and pancreatic cancers by regulating proliferation, migration, invasion and epithelial-mesenchymal transition of cells. The purpose of the present study was to investigate the expression of miR-330-5p in CRC and identify its target gene(s) that may act in CRC tumorigenesis. We found that miR-330-5p expression was significantly lower in CRC tissues than that in adjacent non-tumorous tissues. Furthermore, we identified integrin alpha 5 (ITGA5) as a new target of miR-330-5p and found that it inhibits ITGA5 expression by directly binding to the 3' untranslated region of ITGA5 mRNA. These results suggest that downregulation of miR-330-5p expression may. affect CRC development via modulation of ITGA5 expression.</P>

스포츠 개념 재정립의 필요성과 방향

유환일 ( Yoo Hwanil ),박성주 ( Park Sungjoo ) 한국체육학회 2020 한국체육학회지 Vol.59 No.6

이 논문의 목적은 스포츠 개념에 관한 선행 연구들의 분석을 통해 스포츠 발생상의 유전적 유대를 놀이적 가치, 경쟁성, 신체성으로 전제하고, 이 세 가지 스포츠 본연의 속성들에 대한 기존 개념의 한계점을 지적하며 시대와 사회의 변화에 따른 이들 개념의 확장과 재정립의 필요성을 주장하는 데 있다. 이러한 주장을 펼치기 위해, 먼저 저명한 스포츠철학자들의 스포츠 개념과 관련된 문헌들을 고찰함으로써 그들이 정의하는 스포츠의 개념과 필수 구성요소들을 살펴보았다. 둘째, 오늘날 새로운 스포츠들이 등장함에 따라 일어난 스포츠 개념 논쟁을 분석하고 주요 쟁점을 도출하였다. 끝으로 스포츠 본연의 속성인 놀이적 가치, 경쟁성, 신체성에 대한 확정적 개념의 한계를 지적하고 시대의 변화에 따른 개념 수정의 필요성과 재정립의 방향성을 제시하였다. 본고는 스포츠의 정의와 가치에 대한 평가는 역사와 시대의 맥락 속에서 변해왔기에 스포츠의 내적인 요소만으로 스포츠를 정의하려는 기존 이론들 보다는 사회문화적 맥락에서 스포츠를 정의하려는 시도가 논리적 오류를 최소화할 수 있다는 점에서 시대와 사회의 변화에 따른 스포츠 개념 재정립의 당위성을 논증하는 데 의의가 있다. Assuming the genetic tie of sport to playfuness, competitiveness, and physicality, this paper has two goals as follows: it points out the limitations of existing concepts on these elements of sport; it then emphasizes the necessity of expanding on the concept of sport in light of social change. In order to achieve the goals, this paper reviews the literature by sport philosophers and examines the existent concepts of sport. Next, the main points are examined by analyzing the controversies over the concepts of sport, caused by the emergence of new sports. In the final section, we show the limitations of prior concept of sport, and suggest the necessity, as well as the direction, of conceptual modification of sport. Because the definition and value of sport has been changed over time, this study argues to redefine the concept of sport. In this way, fallacies can be minimized when we define sport within sociocultural context rather than using the existing theory which defines sport based on its inner components only.

Shape-controlled bismuth nanoflakes as highly selective catalysts for electrochemical carbon dioxide reduction to formate

Kim, Sungjoo,Dong, Wan Jae,Gim, Seungo,Sohn, Woonbae,Park, Jae Yong,Yoo, Chul Jong,Jang, Ho Won,Lee, Jong-Lam Elsevier 2017 Nano energy Vol.39 No.-

<P><B>Abstract</B></P> <P>Nanostructured bismuth (Bi) nanoflakes were designed and directly grown on Cu substrate using a novel pulse electrodeposition method. Compared with conventional bismuth film grown by direct current electrodeposition, Bi nanoflakes have large number of edge and corner sites. As it has been proven by numerical simulation, sharp edge or corner sites of the nanostructures form strong local electric fields, which boost the catalytic activity for the electrochemical reduction of CO<SUB>2</SUB> in aqueous solution. The Bi nanoflakes showed a high HCOO<SUP>-</SUP> faradaic efficiency (FE = 79.5%) at low potential of −0.4 V<SUB>RHE</SUB> and achieved a maximum FE close to 100% at −0.6 V<SUB>RHE</SUB>, meaning that the shape control of Bi electrocatalyst is indeed an efficient way to reduce the electrical power consumption for HCOO<SUP>-</SUP> production. Moreover, Bi nanoflakes were stable during 10h operation in 0.1M KHCO<SUB>3</SUB> aqueous solution. The results suggest that tailoring the nanostructure is a key in developing a high performance noble-metal-free electrocatalyst for electrochemical CO<SUB>2</SUB> reduction in aqueous solution.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Bismuth (Bi) nanoflakes were designed and directly grown on Cu substrate using a novel pulse-electrodeposition method. </LI> <LI> Relationship between the shape and catalytic performance was elucidated. </LI> <LI> Electrochemical CO<SUB>2</SUB> reduction with high HCOO<SUP>-</SUP> production rate was achieved at low potential. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Bismuth (Bi) nanoflakes were designed using a novel pulse electrodeposition method. Compared with conventional Bi film grown by direct electrodeposition, Bi nanoflakes have a large number of edge and corner sites, which boost the catalytic activity. The novel-metal-free Bi electrocatalyst achieved highly electrochemical CO<SUB>2</SUB> reduction in aqueous solution.</P> <P>[DISPLAY OMISSION]</P>

Topology Synthesis of Cascaded Crossbar Switches

Minje Jun,Sungjoo Yoo,Eui-Young Chung IEEE 2009 IEEE transactions on computer-aided design of inte Vol.28 No.6

<P>Performance requirements of on-chip network increase as system-on-chips (SoCs) are becoming more and more complex. For high-performance applications, crossbar switch-based networks are replacing the traditional shared buses as the backbone networks in SoCs. In this paper, we tackle the topology design of on-chip networks with crossbar switches in a cascaded fashion. We also resolve the unacceptable complexity of our previous method based on mixed integer linear programming by a heuristic method. Experimental results show that the proposed method overcomes the frequency limitation of the single crossbar-based design, particularly when the wire delay effect is considered. The proposed heuristic method also achieves more area reduction (up to 69.5%) over the existing methods, and finds as good solutions as the exact method while the synthesis time is saved by orders of magnitude.</P>

DVFS Algorithm Exploiting Correlation in Runtime Distribution

Jungsoo Kim,Sungjoo Yoo,Chong-Min Kyung 대한전자공학회 2009 Journal of semiconductor technology and science Vol.9 No.2

Dynamic voltage and frequency scaling (DVFS) is an effective method to achieve low power design. In our work, we present an analytical DVFS method which judiciously exploits correlation information in runtime distribution while satisfying deadline constraints. The proposed method overcomes the previous distribution-aware DVFS method [2] which has pessimistic assumption on which runtime distributions are independent. Experimental results show the correlation-aware DVFS offers 13.3% energy reduction compared to existing distribution-aware DVFS [2].