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Assessment of RANS Models for 3-D Flow Analysis of SMART
Chun Kun Ho,Hwang Young Dong,Yoon Han Young,Kim Hee Chul,Zee Sung Quun Korean Nuclear Society 2004 Nuclear Engineering and Technology Vol.36 No.3
Turbulence models are separately assessed for a three dimensional thermal-hydraulic analysis of the integral reactor SMART. Seven models (mixing length, k-l, standard $k-{\epsilon},\;k-{\epsilon}-f{\mu},\;k-{\epsilon}-v2$, RRSM, and ERRSM) are investigated for flat plate channel flow, rotating channel flow, and square sectioned U-bend duct flow. The results of these models are compared to the DNS data and experiment data. The results are assessed in terms of many aspects such as economical efficiency, accuracy, theorization, and applicability. The standard $k-{\epsilon}$ model (high Reynolds model), the $k-{\epsilon}-v2$ model, and the ERRSM (low Reynolds models) are selected from the assessment results. The standard $k-{\epsilon}$ model using small grid numbers predicts the channel flow with higher accuracy in comparison with the other eddy viscosity models in the logarithmic layer. The elliptic-relaxation type models, $k-{\epsilon}-v2$, and ERRSM have the advantage of application to complex geometries and show good prediction for near wall flows.
Chun, Chi-Sung,Kim, Ji-Hyun,Lim, Hyun-Ae,Sohn, Ho-Yong,Son, Kun-Ho,Kim, Young-Kyoon,Kim, Jong-Sang,Kwon, Chong-Suk The Korean Society of Food Science and Nutrition 2004 Preventive Nutrition and Food Science Vol.9 No.2
The free radical scavenging activities and the protective effects of Rhus javanica extracts against oxidative damage induced by reactive oxygen species (ROS) were investigated. n-Hexane, ethyl acetate and water fractions were prepared from a methanol extract. DPPH radical, superoxide anion and hydroxyl radical scavenging activities were estimated. Intracellular ROS formation was quantified using fluorescent probes, 2', 7'-dichlorofluorescin diacetate (DCFH-DA) for hydroxyl radical and dihydroethidium (DHE) for superoxide anion. The oxidative DNA damage was investigated by the comet assay in HepG$_2$ cells exposed either to $H_2O$$_2$ or to menadione. The highest $IC_{50}$/ values for DPPH radical scavenging activity was found in the ethyl acetate fraction with a value of 5.38 $\mu\textrm{g}$/mL. Cells pretreated with $\geq$ 1 $\mu\textrm{g}$/mL of the ethyl acetate extract had significantly increased cell viability compared to control cells, which were not pretreated with the extract. Intracellular ROS formation and DNA damage in HepG$_2$ cells, which were pretreated with the various concentrations of Rhus javanica ethyl acetate extract and then incubated either with $H_2O$$_2$ or with menadione, reduced in a dose-dependent manner. These findings suggest that Rhus javanica might have biologically active components which have strong protective effects against ROS induced oxidative damages to the biomolecules, such as cell membranes and DNA.
Sung-Jae Kim,Cheongung Kim,Hee-Chun Chung,Yong Ho Park,Kun Taek Park 대한수의학회 2021 Journal of Veterinary Science Vol.22 No.3
Feline calicivirus (FCV) is a highly infectious pathogen in cats and widely distributed worldwide with high genetic variation. Full-length open reading frame 2 of 5 from recently isolated Korean FCV isolates were sequenced and compared with those of global isolates. The results of phylogenetic analysis supported dividing global FCV isolates into two genogroups (type I and II) and demonstrated the presence of genogroup II in Korea, indicating their geographic spread in East Asia. High sequence variations in region E of the FCV isolates emphasizes that a novel vaccine needs to be developed to induce protective immunity against various FCV strains.