혼합 식물추출물에 대한 차응애의 감수성 검정

김창승(Chang Seung Kim),김도익(Do Ik kim),국용인(Yong In Kuk),현규환(Kyu Hwan Hyun),김상수(Sang Soo Kim1) 한국차학회 2016 한국차학회지 Vol.22 No.1

The acaricidal activity of the mixed plant extracts of Gleditsia japonica var. koraien, Camellia sinensis, Cinnamomum cassia, and Lantana camara, toward the tea red spider mite, Tetranychus kanzawai Kishida was evaluated in laboratory bioassays. Treatments with mixtures 1 and 3 were effective against the adult females of T. kanzawai and yielded 87.0 and 85.6% adulticidal activity at 7 days after treatment, respectively. Mixture 3 revealed 78.7% adulticidal activity. However, mixtures 4 and 5 had lower adulticidal activity than the other treatments. The adult females of T. kanzawai treated with mixtures 1 and 3 produced only 22.5-22.8% as many eggs as did the control females. The residue of the plant extracts tested had low adulticidal activity (16.3-27.2%). All of the plant extracts tested were ineffective against the eggs of T. kanzawai. Treatments with mixtures 1 and 3 were effective against the nymphs of T. kanzawai and led to emergence rates of 20.7 and 25.3%, respectively. These results suggest that mixtures 1 and 3 might be used for the control of T. kanzawai.

<SUP>18</SUP>F-FDG PET-CT에서 진단된 갑상선 우연종의 악성종양 발견율 및 특징

이강영,고건<SUP>1<.SUP>,김선국<SUP>1<.SUP>,고진철<SUP>1<.SUP>,김행수,최상용,박신희,박용휘<SUP>2<.SUP>,Kang Young Rhee,Gun Koh,<SUP>1<.SUP>,Sun Kuk Kim,<SUP>1<.SUP>,Jin Chul Koh,<SUP>1<.SUP>,Haeng Soo Kim,Sang Yong Choi,Shin 대한갑상선-내분비외과학회 2008 The Koreran journal of Endocrine Surgery Vol.8 No.1

<B>Purpose: </B>PET-CT is often used to differentiate benign or malignant thyroid incidentalomas. In this retrospective study, we evaluated whether the <SUP>18</SUP>F-FDG uptake pattern and PET-CT findings improved accuracy over the standardized uptake value (SUV). <B>Methods:</B> <SUP>18</SUP>F-FDG PET-CT was performed on 2,178 subjects from August, 2004, to October, 2007, in Sung-ae Hospital. PET-CT was performed on 806 patients (37%) with suspected or known nonthyroidal cancer and 1,372 healthy subjects (63%) without a previous history of cancer. We investigated the clinical characteristics of patients, history, standardized uptake value (SUV), ultrasonography, and hormone levels in blood. Thyroidal cancer was confirmed by ultrasonography-guided fine needle aspiration and pathology after thyroid operation. <B>Results:</B> The prevalence of focal thyroid lesions on PET-CT was 8.8% (191/2178). Thyroid cancer confirmation was 7.9% (15/191). The maximum SUV of malignant thyroid lesions were significantly higher than that of benign lesions (7.00±3.08 vs. 4.49±1.84, P<0.001). <B>Conclusion:</B> PET-CT image interpretation that includes 18F-FDG uptake and SUV is better than PET-CT alone for differentiating benign and malignant lesions. Thyroid cancer risk increases as SUVmax levels increase. <B>(Ko</B><B></B><B>rean J Endocrine Surg 2008;8:38-42)</B>

김만덕의 기업가정신에 대한 연구

양성국(Sung-kuk Yang),김봉현(Bong-hyun Kim) 한국경영사학회 2012 經營史學 Vol.62 No.-

본 연구의 목적은 김만덕이 성공한 CEO로서 보여준 기업가정신을 체계적으로 살펴보고, 그녀가 지녔던 기업가정신이 우리에게 주는 시사점을 도출하는데 있다. 논문은 크게 두 부분으로 구성되어 있다. 첫 번째는 김만덕의 생애와 김만덕이 CEO로 역할을 수행했던 당시의 시대적 배경을 살펴보았다. 두 번째는 김만덕이 보여준 기업가정신을 분석하여 시사점을 도출하고자 하였다. 이를 위하여 먼저 기업가정신의 일반적인 내용을 살펴본 후, 조선시대 최초 여성 CEO 김만덕의 기업가정신을 분석하여 시사점을 찾고자 하였다. 김만덕이 보여준 기업가정신을 파악하기 위하여 개인 차원에서 기업가정신을 연구한 Chrisman et al.(1998)이 제시한 특성 중에서 창업 경험을 제외하고 인성적 특성, 가치 및 신념, 능력, 행동적 특성 등 4가지 관점에서 김만덕이 보여준 기업가정신을 분석하였다. 김만덕에 관한 대부분의 기록과 작품들은 김만덕의 삶과 행적을 긍정적으로 묘사하고 있다. 따라서 김만덕의 삶을 객관적으로 조명하는 가운데 김만덕이 보여준 기업가로서 의 정신적 가치를 발굴하고 현대적 관점에서 재평가하는 작업은 필요하다. 다만 제한된 지면의 사료나 자료에 의존하여 이루어진 평가이기 때문에 주의가 필요하다고 생각된다. The purpose of this paper was to identify the entrepreneurship of Kim Man Deok. This paper was divided into two parts : first is the Kim Man Deok s life stages and characteristic of the age, second is the entrepreneurship of Kim Man Deok. Kim Man Deok‘s life was divided into three time periods : fight against fate, as a CEO, donating her possession to society. And the entrepreneurship of Kim Man Deok were examined : personality and characteristics, values and beliefs, skills, behaviors and decisions. Kim Man Deok(1739-1812), who was living in Jeju Island. She became one of the richest persons living on Jeju Island after overcoming various difficulties in the previous 200 years. Kim Man deok was the first female CEO in Korean history. Kim Man Deok was a shrewd entrepreneur, who knew how to foresee future trends and stood apart from other great women of the Joseon era. Kim Man Deok s life inspired Jeju residents and remains one of the most respected figures.

Dormancy-related Change in Endogenous ABA, Batatasin, and Sugar in Stored Tuber and Bulbil of Chinese Yam

Sang-Kuk Kim,Sang-Chul Lee,Tae-Shik Park,Soon-Tae Kwon,In-Jung Lee 韓國作物學會 2002 한국작물학회지 Vol.47 No.4

Endogenous ABA and batatasins were first quantified in the stored tubers and bulbils of the Chinese yam, Dioscorea opposita Thunb. cv. 'Tsukune' by GC-MS with comparison of internal standard, and sugar content was also analyzed by HPLC with comparison of external standard. Endogenous ABA content in stored tubers and bulbils was rapidly decreased as storage period prolonged. ABA content of the bulbils was always higher than that of tuber during storage periods. All batatasins of stored tubers and bulbils at 30 days after storage decreased steadily compared to 120 days after storage. On the contrary, batatasin-Ⅲ of the stored tuber and bulbils was only decreased at 60 days after storage. In Dioscorea opposita Thunb. cv. 'Tsukune' like D. japonica, D. alata, and D. bulbifera, may be controlled by endogenous batatasins and ABA, In these compounds, batatasins rather than ABA might be closely related to dormancy-inducing compound during dormancy of the Chinese yam, Dioscorea opposita Thunb. cv. Tsukune.

Antibacterial and Antifungal Activities of a Naphthoquinone Derivative Isolated from the Fruits of Catalpa ovata G. Don

KUK, JU-HEE,MA, SEUNG-JIN,MOON, JAE-HAK,KIM, KIL-YONG,CHOI, SANG-HO,PARK, KEUN-HYUNG 한국미생물 · 생명공학회 2002 Journal of microbiology and biotechnology Vol.12 No.5

An antimicrobial compound was isolated from the MeOH extract of Catalpa ovata G. D_ON fruits, and its structure was identified as 4, 9-dihydroxy-2, 2-dimethyl-3, 4-dihydronaphtho[2, 3-b]pyran-5, 10-dione (HMNP). The antimicrobial activity of the HMNP was determined by measuring the dose-response inhibition of microbial growth in liquid cultures and then compared with that of lapachol, a well known antimicrobial 1, 4-naphthoquinone. The antimicrobial activity of the HMNP was more effective than that of lapachol over a wide range of test organisms. Gram-positive bacteria, yeast, and fungi (IC_50 20-75㎛) were found to be more sensitive to the HMNP than Gram-negative bacteria (IC_50>100㎛). The HMNP also inhibited germination of spores of many fungi. The morphological deformation of the fungal spores was induced by the treatment of HMNP, as illustrated by Scanning Electron Microscopy (SEM).

Amniopatch treatment for preterm premature rupture of membranes before 23 weeks' gestation and factors associated with its success

Sung, J.H.,Kuk, J.Y.,Cha, H.H.,Choi, S.J.,Oh, S.y.,Roh, C.R.,Kim, J.H. Elsevier (Singapore) 2017 Taiwanese journal of obstetrics & gynecology Vol.56 No.5

Objective: The purpose of this study is to investigate the factors associated with successful amniopatch treatment in patients with iatrogenic preterm premature rupture of membranes (iPPROM) or spontaneous PPROM (sPPROM) before 23 weeks' gestation. Materials and methods: This cohort study included 28 women who received amniopatch treatment due to iPPROM or sPPROM at 15-23 weeks' gestation. Patients' clinical characteristics before performing the amniopatch, factors associated with the procedure, pregnancy and neonatal outcomes were compared between the iPPROM and sPPROM groups, and also between the successful and failed groups. Results: The amniopatch was successful in 6 of 28 patients (21.4%) with a success rate of 36.4% (4/11) and 11.8% (2/17) in the iPPROM group and sPPROM group (P = 0.174), respectively. The success group had a longer PPROM-to-delivery interval, fewer cases of clinical chorioamnionitis, larger birth weight, and lower neonatal intensive care unit admission rate than the failed group. The success rate of amniopatch procedure was proportional to maximal vertical pocket prior to procedure, which showed statistically significant association (adjusted odds ratio: 3.62, 95% confidence interval: 1.16-11.31, P = 0.027). Conclusion: The amniopatch treatment success rate was higher in the iPPROM group than the sPPROM group, but was not statistically significant. The neonatal outcome was more favorable when the amniopatch was successful. However, the only predictive factor associated with successful amniopatch was a larger amniotic fluid volume before the procedure.

Effect of ethanol and glycerol on suppression rates of various crop pathogens

Kim, Yeo Hyeon,Jang, Se Ji,Yun, Young Beom,Kim, Sang Soo,Kuk, Yong In Gaurav Publications 2017 Research on Crops Vol.18 No.1

Effect by acupuncture on hypothalamic expression of maternally separated rats: proteomic approach.

Kim, Hak-Jae,Park, Hae Jeong,Hong, Mee Sook,Song, Jeong Yoon,Park, Hyun-Kyung,Jo, Dae Jean,Park, Sung Wook,HwanYun, Dong,Park, Hun-Kuk,Yang, Jong-Soo,Ban, Ju Yeon,Chung, Joo-Ho Butterworths [etc.] 2010 Neurological research Vol.32 No.suppl1

<P>OBJECTIVES: Early stressors can influence the development of biological and neurological systems. Maternal separation (social isolation) in early life may increase vulnerability to neurodegenerative diseases and neuropsychiatric disorders over the lifespan. To identify new proteins on acupuncture effects in maternally separated rats, an animal model for study of early environmental insults, proteomic approach on the expression of the hypothalamic proteins was performed. METHODS: On post-natal day 14, rat pups were randomly divided into four groups: pups kept with their mothers for 7 days; pups kept with their mothers with acupuncture daily to HT8 (Sobu); maternally separated pups; maternally separated pups with acupuncture. The hypothalamic proteins were analysed by two-dimensional electrophoresis coupled with matrix assisted laser desorption/ionization time-of-flight mass spectrometer. RESULTS: The results showed that 27 spots were differentially and commonly expressed. Of 27 spots, 21 spots were identified while six spots were not, and 15 proteins were known proteins. In maternally separated group, the expressions of 14 proteins were down-regulated, compared to control group. In group of maternally separation with acupuncture, five proteins were down-regulated and nine were up-regulated, compared to the maternally separated group. Among nine proteins up-regulated by acupuncture treatment, we found four proteins (dihydropyrimidinase-like 2, dystrophin-related protein 2, tubulin, alpha 1a and syntaxin 1b) related to neurodevelopment. DISCUSSION: The result suggests that acupuncture to HT8 may affect neurodevelopment, and acupuncture may be a possible therapy for neurodevelopmental disorders.</P>

Microstructure and Mechanical Properties of Cr-Mo Steels for Nuclear Industry Applications

Kim, Sung-Ho,Ryu, Woo-Seong,Kuk, Il-Hiun Korean Nuclear Society 1999 Nuclear Engineering and Technology Vol.31 No.6

Microstructure and mechanical properties of five Cr-Mo steels for nuclear industry applications have been investigated. Transmission electron microscopy, energy dispersive spectrometer, differential scanning calorimeter, hardness, tensile, and impact test were used to evaluate the Cr and W effect on the microstructure and mechanical properties. Microstructures of Cr-Mo steels after tempering are classified into three types : bainitic 2.25Cr-lMo steel, martensitic Mod.9Cr-lMo, HT9M, and HT9W steels, and dual phase HT9 steel. The majority of the precipitates were found to be M$_{23}$C$_{6}$ carbides. As minor phases, fine needle-like V(C,N), spherical NbC, fine needle-like Cr-rich Cr$_2$N, and Cr-rich M$_{7}$C$_3$were also found. Addition of 2wt.% W in Cr-Mo steels retarded the formation of subgrain and dissolution of Cr$_2$N precipitates. Hardness and ultimate tensile strength increased with increasing Cr content. Though Cr content of HT9W steel was lower than that of HT9 steel, the hardness of HT9W was higher due to the higher W content. W added HT9W steel had the highest ultimate tensile strength above $600^{\circ}C$. But impact toughness of W added steel (HT9W) and high Cr steel (HT9) was low.w.w.

Prognosis following dental implant treatment under general anesthesia in patients with special needs

Kim, Il-hyung,Kuk, Tae Seong,Park, Sang Yoon,Choi, Yong-suk,Kim, Hyun Jeong,Seo, Kwang-Suk The Korean Dental Society of Anesthsiology 2017 Journal of Dental Anesthesia and Pain Medicine Vol.17 No.3

Background: This study retrospectively investigated outcomes following dental implantation in patients with special needs who required general anesthesia to enable treatment. Method: Patients underwent implant treatment under general anesthesia at the Clinic for the Disabled in Seoul National University Dental Hospital between January 2004 and June 2017. The study analyzed medical records and radiographs. Implant survival rates were calculated by applying criteria for success or failure. Results: Of 19 patients in the study, 8 were males and 11 were females, with a mean age of 32.9 years. The patients included 11 with mental retardation, 3 with autism, 2 with cerebral palsy, 2 with schizophrenia, and 1 with a brain disorder; 2 patients also had seizure disorders. All were incapable of oral self-care due to serious cognitive impairment and could not cooperate with normal dental treatment. A total of 27 rounds of general anesthesia and 1 round of intravenous sedation were performed for implant surgery. Implant placement was performed in 3 patients whose prosthesis records could not be found, while 3 other patients had less than 1 year of follow-up after prosthetic treatment. When the criteria for implant success or failure were applied in 13 remaining patients, 3 implant failures occurred in 59 total treatments. The cumulative survival rate of implants over an average of 43.3 months (15-116 months) was 94.9%. Conclusion: For patients with severe cognitive impairment who are incapable of oral self-care, implant treatment under general anesthesia showed a favorable prognosis.