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Bilateral Bipartite Carpal Scaphoid
Sang-Bum Kim(김상범),Woo-Sik Kim(김우식),Whan-Yong Chung(정환용),Taek-Soo Jeon(전택수),In-Tak Bae(배인탁) 대한정형외과학회 2005 대한정형외과학회지 Vol.40 No.5
이분 주상골은 드문 기형이며 아직도 그 선천성 혹은 외상성의 논란의 여지는 있으나 대부분의 보고가 선천성의 가능성을 시사 하고 있다. 현재 까지 이분 주상골에 대한 국내 증례보고는 없었으며 이에 저자들은 38세 남자의 이분 주상골의 증례를 경험하였기에 문헌 고찰과 함께 보고하고자 한다. Bipartite scaphoid is a rare anomaly and it has been questioned as whether it is of congenital origin or traumatic. However, many authors have reported that congenital origin is more probable. There was no case report in Korea about bipartite scaphoid, but this article reports a case of a 38-year-old male with bilateral bipartite scaphoid.
FC 1-13 : Expression of extracellular superoxide dismutase protein in diabetes
( Bum Joon Ko ),( Han Eul Lee ),( Gang Mo Lee ),( Je Min An ),( You In Bae ),( Sung Yul Lee ),( Moon Kyun Cho ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: Diabetes is characterized by chronic hyperglycemia, which can increase reactive oxygen species (ROS) production by the mitochondrial electron transport chain. The formation of ROS induces oxidative stress and activates oxidative damage-inducing genes in cells. No research has been published on oxidative damage-related extracellular superoxide dismutase (EC-SOD) protein levels in human diabetic skin. We investigated the expression of EC-SOD in diabetic skin compared with normal skin tissue in vivo. Objectives: To compare the expression of EC-SOD in normal skin versus diabetic skin. Methods: The expression of EC-SOD protein was evaluated by western blotting in 6 diabetic skin tissue samples and 6 normal skin samples. Immunohistochemical staining was also carried out to confirm the EC-SOD expression level in the 6 diabetic skin tissue samples. Results: The western blotting showed significantly lower EC-SOD protein expression in the diabetic skin tissue than in the normal tissue. Immunohistochemical examination of EC-SOD protein expression supported the western blotting analysis. Conclusion: Diabetic skin tissues express a relatively small amount of EC-SOD protein and may not be protected against oxidative stress. We believe that EC-SOD is related to the altered metabolic state in diabetic skin, which elevates ROS production.
Sung-Jae Park,Sang-Bum Bae,Su-Kyoung Kim,Tae-Gwan Eom,Seung-Il Song 대한구강악안면외과학회 2011 대한구강악안면외과학회지 Vol.37 No.3
Objective: This study examined the potential of the in vitro osteogenesis of microtopographically modified surfaces, RBM (resorbable blasting media) surfaces, which generate hydroxyapatite grit-blasting. Methods: RBM surfaces were modified hydroxyapatite grit-blasting to produce microtopographically modified surfaces and the surface morphology, roughness or elements were examined. To investigate the potential of the in vitro osteogenesis, the osteoblastic cell adhesion, proliferation, and differentiation were examined using the human osteoblast-like cell line, MG-63 cells. Osteoblastic cell proliferation was examined as a function of time. In addition, osteoblastic cell differentiation was verified using four different methods of an ALP activity assay, a mineralization assay using alizarin red-s staining, and gene expression of osteoblastic differentiation marker using RT-PCR or ELISA. Results: Osteoblastic cell adhesion, proliferation and ALP activity was elevated on the RBM surfaces compared to the machined group. The cells exhibited a high level of gene expression of the osteoblastic differentiation makers (osteonectin, type I collagen, Runx-2, osterix). imilar data was represented in the ELISA produced similar results in that the RBM surface increased the level of osteocalcin, osteopontin, TGF-beta1 and PGE2 secretion, which was known to stimulate the osteogenesis. Moreover, alizarin red-s staining revealed significantly more mineralized nodules on the RBM surfaces than the machined discs. Conclusion: RBM surfaces modified with hydroxyapatite grit-blasting stimulate the in vitro osteogenesis of MG-63 cells and may accelerate bone formation and increase bone-implant contact.
Bae Seongman,Lee Yun Woo,Lim So Yun,Lee Ji-Hyang,Lim Joon Seo,Lee Sojeong,Park Soyeon,Kim Sun-Kyung,Lim Young-Ju,Kim Eun Ok,Jung Jiwon,Kwon Hyouk-Soo,Kim Tae-Bum,Kim Sung-Han 대한의학회 2021 Journal of Korean medical science Vol.36 No.17
Background: We performed a prospective survey on the adverse reactions following the first dose of two types of vaccines against coronavirus disease 2019 (COVID-19) in healthcare workers (HCWs) in South Korea. Methods: HCWs at a tertiary referral hospital in Seoul, South Korea, received a chimpanzee adenovirus-vectored vaccine (ChAdOx1 nCoV-19) or an mRNA-based vaccine (BNT162b2) between March 5 and March 26, 2021. The HCWs were asked to report adverse reactions through a mobile self-report questionnaire for three days after vaccination. Results: A total of 7,625 HCWs received the first dose of ChAdOx1 or BNT162b2 vaccine during the study period. Of them, 5,866 (76.9%) HCWs (ChAdOx1, n = 5,589 [95.3%]; BNT162b2, n = 277 [4.7%]) participated at least once in the survey, of whom 77% were female and 86% were younger than 50 years. The overall adverse reaction rate was 93% in the ChAdOx1 group and 80% in the BNT162b2 group (P < 0.001). Both local and systemic reactions were more commonly reported in the ChAdOx1 group, and the difference was larger in systemic reactions such as fever and fatigue. In the ChAdOx1 group, the incidence of adverse reactions was significantly higher in females and those in the younger age groups, while the BNT162b2 group showed such difference according to age. Conclusion: In our prospective survey, vaccine-associated adverse reactions were more commonly reported in the ChAdOx1 group than in the BNT162b2 group. Females and younger age groups experienced vaccine-associated adverse reactions more frequently.
Control Method of Modular Interleaved Boost Converter for SOC Balancing in EV
Sung-Hoon Bae,Seong-Chon Choi,Bum-Jun Kim,Young-Ryul Kim,Chung-Yuen Won 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6
This paper proposes control method of Differential Discharge Handling (DDH) modules with state of charge(SOC) balancing between battery modules in Electric Vehicle (EV) system. The DDH modules are composed of battery modules and converter modules. To achieve high efficiency, the diode is replaced by MOSFET to use the synchronous boost converter. In order to reduce the ripple of input/output voltage and current, it uses interleaved method. Interleaved converter operation is analyzed according to switching state by using state space averaging method. In order to design controller of the DDH converter, a control transfer function is obtained by using small signal modeling. The proposed SOC balancing algorithm maintains constant DC-link voltage and increases the utilization rate of the battery modules, as performing the discharge balancing between the modules by handling the discharge amount of the battery modules. Experimental results verify the proposed SOC balancing algorithm.