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전석기(Sukky Jun),조영삼(Young-Sam Cho),임세영(Seyoung Im) 대한기계학회 2003 대한기계학회 춘추학술대회 Vol.2003 No.4
The moving least square (MLS) basis is implemented for the real-space band-structure calculation of 2D<br/> photonic crystals. The value-periodic MLS shape function is thus used in order to represent the periodicity of<br/> crystal lattice. Any periodic function can properly be reproduced using this shape function. Matrix eigenequations,<br/> derived from the macroscopic Maxwell equations, are then solved to obtain photonic band<br/> structures. Through numerical examples of several lattice structures, the MLS-based method is proved to be a<br/> promising scheme for predicting band gaps of photonic crystals.
조영삼(Young-Sam Cho),전석기(Sukky Jun),임세영(Seyoung Im) 대한기계학회 2004 대한기계학회 춘추학술대회 Vol.2004 No.4
We propose a 2D 'crack' element for the simulation of propagating crack with minimal remeshing. A regular finite element containing the crack tip is replaced with this novel crack element, while the elements which the crack has passed are split into two transition elements. Singular elements can easily be implemented into this crack element to represent the crack-tip singularity without enrichment. Both crack element and transition element proposed in our formulation are mapped from corresponding master elements which are commonly built using the moving least-square (MLS) approximation only in the natural coordinate. In numerical examples, the accuracy of stress intensity factor K<SUB>I</SUB> is demonstrated and the crack propagation in a plate is simulated.
Jang, Hyo Joon,Cho, Sukki,Kim, Kwhanmien,Jheon, Sanghoon,Yang, Hee Chul,Kim, Dong Kwan Korean Cancer Association 2017 Cancer Research and Treatment Vol.49 No.4
<P><B>Purpose</B></P><P>We conducted a retrospective analysis to determine if adjuvant chemotherapy prolongs overall survival in patients with pathologic stage IB lung adenocarcinoma who had undergone complete resection and were defined as high-risk by a newly developed recurrence risk scoring model.</P><P><B>Materials and Methods</B></P><P>Patients who underwent curative resection for stage IB lung adenocarcinoma were analyzed with a newly developed recurrence risk scoring model and divided into a low-risk group and a high-risk group. The patients in the high-risk group were retrospectively divided into two groups based on whether they underwent adjuvant chemotherapy or observation. Recurrence-free survival and overall survival were compared between these two groups.</P><P><B>Results</B></P><P>A total of 328 patients who underwent curative resection between 2000 and 2009 were included in this study, of whom 110 (34%) received adjuvant chemotherapy and 218 (67%) underwent observation without additional treatment. According to our risk model, 167 patients (51%) were high-risk and 161 (49%) were low-risk. The 5-year recurrence-free survival rates and overall survival were 84.4% and 91.5% in low-risk patients and 53.9% and 74.7% in high-risk patients (p < 0.001). In high-risk patients, the 5-year overall survival rates were 77% among patients who underwent observation and 87% among those who underwent adjuvant chemotherapy (p=0.019).</P><P><B>Conclusion</B></P><P>Adjuvant chemotherapy prolonged overall survival among high-risk patients who had undergone complete resection for stage IB lung adenocarcinoma.</P>
( Ga Young Lee ),( Sukki Cho ),( Jin-haeng Chung ),( Hyung-jun Kim ),( Myung Jin Song ),( Byung Soo Kwon ),( Sung Yoon Lim ),( Yeon-joo Lee ),( Jong Sun Park ),( Young-jae Cho ),( Ho Il Yoon ),( Jae H 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Background Spread through air spaces (STAS) is a recently determined pathologic phenomenon of lung cancers with significant impact on prognosis. However, the possible influence of mechanical forces caused by diagnostic interventions on the occurrence of STAS has not yet been explored. The purpose of this study was to evaluate the association of diagnostic lung biopsy on the risk of STAS, and its prognostic impact in resected stage I NSCLC. Methods We performed a retrospective review of 2,238 patients who underwent surgery for stage I NSCLC, from January 2011 to December 2019 in Seoul National University Bundang Hospital. The risk factors for STAS was assessed by logistic regression. In addition, the association between previous diagnostic lung biopsy and incidence of recurrence, lung cancer-related mortality were assessed stratified by STAS positivity with Multivariate Cox’s regression analyses and the Kaplan-Meier method. Results Of the 2,238 patients analyzed, 677(30.2%) patients had positive STAS. Lung cancer with STAS tended to be solid tumors with greater tumor size and T stage. In the univariate logistic regression analysis for the risk of STAS, previous percutaneous needle biopsy (OR=1.81, P<0.001), bronchoscopic biopsy (OR=1.42, P<0.030), bronchoscopic washing and BAL(OR=1.41, P<0.005) were all significantly associated with the risk for STAS. However, in the multivariate analysis, only solid type(OR=2.54,P<0.001) and tumor size (OR=1.76, P<0.001) remained significant for STAS positivity. Multivariate Cox proportional hazards models showed that after adjustments for previous diagnostic procedures, STAS was a significant risk factor for cancer recurrence(OR=1.62, P=0.005). In addition, for STAS positive patients, sublobar resection remained a significant risk factor for recurrence(OR=2.93, P<0.001) and lung cancer related mortality(OR= 9.58, P<0.001) after adjustments for previous diagnostic procedures. Conclusions Previous lung biopsy and intervention in stage I NSCLC are not associated with the development of STAS, and do not affect the prognosis of NSCLC related to STAS.
조영삼(Young-Sam Cho),전석기(Sukky Jun),김성엽(Sung Youb Kim),임세영(Seyoung Im) 대한기계학회 2003 대한기계학회 춘추학술대회 Vol.2003 No.11
Strain-induced bandgap tuning of 2D silicon-based photonic crystals is performed using a real-space computation of band structures. We have proved that the uniaxial tension mode is more effective for bandgap tuning than both pure and simple shear deformations. We further verify that these bandgap modifications rely on the deformation-induced distortion of interfaces between inclusions and matrix. Our numerical results strongly imply that the real-space technique is indispensable for the accurate calculation of strained photonic bandgap materials.
Dual roles of a variable number of tandem repeat polymorphism in the TERT gene in lung cancer
Jin, Guang,Yoo, Seung Soo,Cho, Sukki,Jeon, Hyo-Sung,Lee, Won-Kee,Kang, Hyo-Gyoung,Choi, Yi Young,Choi, Jin Eun,Cha, Sung-Ick,Lee, Eung Bae,Kim, Chang Ho,Jung, Tae Hoon,Kim, Young Tae,Park, Jae Yong Wiley (Blackwell Publishing) 2011 CANCER SCIENCE Vol.102 No.1