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      • 상용차 기반에 대한 주차보조시스템 사용자 감성 평가

        전재석(Jaeseok Jeon),박현배(Hyunbae Park),문희석(Heeseok Moon),곽수진(Sujin Kwag) 한국자동차공학회 2013 한국자동차공학회 부문종합 학술대회 Vol.2013 No.5

        In this paper, we described about evaluation of human sensibility using park assist system of the commercial vehicle. The perpendicular parking and parallel parking have been carried out as a user test and subjects are classified as beginning drivers, drivers with less than 1 year experience and over 3 years experience. As a result, parking duration of beginning drivers and drivers with less than 1 year experience who use automatic parking assistance system is similar to drivers with over 3 years experience. However error occurred according to sensor position and distance between vehicle and parking space. And also it occurred that the vehicle leaves from parking line or does not recognize the parking space. Therefore, if we improve its completeness by compensating problems that came up from this evaluation and distribute the automatic parking assistance system, it is expected that the park assistance system is to help driver providing convenience of parking.

      • KCI우수등재

        도시녹지 유형에 따른 휘발성유기화합물 농도 특성

        조예슬(Yeseul Jo),박수진(Sujin Park),노관평(Gwan Pyeong Roh) 한국환경보건학회 2018 한국환경보건학회지 Vol.44 No.4

        Objectives: The occurrence characteristics of BTEXS and phytoncides were investigated by type of urban forest. Methods: Four types of urban green space (Hongneung Forest, Mt. Chunjang, residential park, and traffic island) and Gwangneung Forest were selected. Monitoring of phytoncides and BTEXS was conducted considering the activity times of urban residents (five times per day) using a Tenax TA tube and suction pump in June 2017 (one day). Results: Phytoncide concentrations were ranked as Gwangneung Forest>Hongneung Forest>Mt. Cheonjang> traffic island>residential park. Relatively high concentrations of phytoncides were also identified in the urban forest. There was no significant difference between Gwangneung Forest and the urban forest. BTEXS concentrations were ranked as traffic island>residential park>Hongneung Forest>Gwangneung Forest>Mt. Cheonjang. Traffic island and residential park showed high levels of BTEXS depending on the inflow of vehicles. The difference in concentration by time was significant for the traffic island in particular. Pollutant levels in Hongneung Forest were as low as in Gwangneung Forest. Conclusion: The concentrations of phytoncides and BTEXS were different by types of urban green space, and the potential for health and hygiene of urban forests were able to be investigated. This study is expected to provide as basic data for the creation of urban forest spaces in the future.

      • Arctic Primary Aerosol Production Strongly Influenced by Riverine Organic Matter

        Park, Jiyeon,Dall’Osto, Manuel,Park, Kihong,Kim, Jung-Hyun,Park, Jongkwan,Park, Ki-Tae,Hwang, Chung Yeon,Jang, Gwang Il,Gim, Yeontae,Kang, Sujin,Park, Sanghun,Jin, Yong Keun,Yum, Seong Soo,Simó American Chemical Society 2019 Environmental science & technology Vol.53 No.15

        <P>The sources of primary and secondary aerosols in the Arctic are still poorly known. A number of surface seawater samples-with varying degrees of Arctic riverine and sea ice influences-were used in a sea spray generation chamber to test them for their potential to produce sea spray aerosols (SSA) and cloud condensation nuclei (CCN). Our interdisciplinary data showed that both sea salt and organic matter (OM) significantly influenced the SSA production. The number concentration of SSA in the coastal samples was negatively correlated with salinity and positively correlated with a number of OM tracers, including dissolved and chromophoric organic carbon (DOC, CDOM), marine microgels and chlorophyll <I>a</I> (Chl-<I>a</I>) but not for viral and bacterial abundances; indicating that OM of riverine origin enhances primary aerosol production. When all samples were considered, transparent exopolymer particles (TEP) were found to be the best indicator correlating positively with the ratio number concentration of SSA/salinity. CCN efficiency was not observed to differ between the SSA from the various samples, despite differences in organic characteristics. It is suggested that the large amount of freshwater from river runoff have a substantial impact on primary aerosols production mechanisms, possibly affecting the cloud radiative forcing.</P> [FIG OMISSION]</BR>

      • KCI등재

        Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation

        Park, Sujin,Yang, Kyung-Min,Park, Yuna,Hong, Eunji,Hong, Chang Pyo,Park, Jinah,Pang, Kyoungwha,Lee, Jihee,Park, Bora,Lee, Siyoung,An, Haein,Kwak, Mi-Kyung,Kim, Junil,Kang, Jin Muk,Kim, Pyunggang,Xiao, Korean Society of Cancer Prevention 2018 Journal of cancer prevention Vol.23 No.1

        <P><B>Background</B></P><P>Smad3 linker phosphorylation plays essential roles in tumor progression and metastasis. We have previously reported that the mutation of Smad3 linker phosphorylation sites (Smad3-Erk/Pro-directed kinase site mutant constructs [EPSM]) markedly reduced the tumor progression while increasing the lung metastasis in breast cancer.</P><P><B>Methods</B></P><P>We performed high-throughput RNA-Sequencing of the human prostate cancer cell lines infected with adenoviral Smad3-EPSM to identify the genes regulated by Smad3-EPSM.</P><P><B>Results</B></P><P>In this study, we identified genes which are differentially regulated in the presence of Smad3-EPSM. We first confirmed that Smad3-EPSM strongly enhanced a capability of cell motility and invasiveness as well as the expression of epithelial-mesenchymal transition marker genes, <I>CDH2</I>, <I>SNAI1</I>, and <I>ZEB1</I> in response to TGF-β1 in human pancreatic and prostate cancer cell lines. We identified <I>GADD45B</I>, <I>CTGF</I>, and <I>JUNB</I> genes in the expression profiles associated with cell motility and invasiveness induced by the Smad3-EPSM.</P><P><B>Conclusions</B></P><P>These results suggested that inhibition of Smad3 linker phosphorylation may enhance cell motility and invasiveness by inducing expression of <I>GADD45B</I>, <I>CTGF</I>, and <I>JUNB</I> genes in various cancers.</P>

      • KCI등재후보

        Deposition and XPS Study of Pb, Zr, and Ti Films

        Sujin Choi, Juyun Park, Eunkang Jeong, Beob jun Kim, Seo yoon Son, Jeong min Lee, Jin seong Lee, Hee jin Jo, Jihun Park, Yong-Cheol Kang 조선대학교 기초과학연구원 2014 조선자연과학논문집 Vol.7 No.3

        Lead zirconate titanate (PZT) is significant material in electrical and optical devices for their ferroelectric, piezoelectric and dielectric properties. In this research, PZT films were fabricated by reactive RF co-sputtering method using Pb, Zr, and Ti targets. From XPS study, lead, zirconium, and titanium are successfully deposited on Si(100) substrate. Thickness of PZT films was measured with a surface profiler and the thickness was decreased as the oxygen gas ratio increased in the sputter gas.

      • Mechanobiological Regulation of Cells by Nanotopographically-defined Biomimetic Scaffolds for Animal Tissue Engineering

        ( Sujin Kim ),( Sunho Park ),( Daun Kim ),( Woochan Kim ),( Dohyeon Lee ),( Sungmin Park ),( Jangho Kim ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        Living cells are exposed to complex and functional microenvironment including soluble macromolecules, biophysical cues, and interactions between cell-cell and cell-extracellular matrix (ECM). This suggests that the design and manipulation of engineered cellular microenvironments is of great important in a wide variety of biological applications such as fundamental biology, therapeutic and diagnostic research, stem cells and regenerative medicine, and developing in vitro disease models. In this work, we described the development of nanoscale engineered biomimetic systems for animal tissue engineering. Specifically, we showed the nanoscale patterned scaffolds inspired by the unique architectures of native animal tissues and ECMs that can provide cells the in vivo-like topographical cell environment, and their applications for better understanding of the function of living animal cells and tissue regeneration without complex surgical treatments.

      • KCI등재

        Successful Treatment of Recalcitrant Plantar Warts Using Combined Long-pulsed Nd:YAG and Alexandrite Lasers

        Sujin Park,Hyun Kim,Eun Ji Kang,Sang Ho Oh,Jihee Kim 대한의학레이저학회 2022 MEDICAL LASERS Vol.11 No.1

        Verruca (wart) is a common cutaneous disease caused by the human papillomavirus (HPV). Plantar warts are frequently associated with HPV genotypes 57, 27, 1, and 2. While some plantar warts can spontaneously regress, many patients undergo treatment with topical salicylic acid, cryotherapy, intralesional bleomycin injection, and laser therapy. Pulsed dye lasers have been used to treat verruca effectively by targeting the dilated vessels in the dermis. More recently, lasers with deeper penetration, such as the 1064-nm long-pulsed neodymium:yttrium-aluminum-garnet (Nd:YAG) and the 755-nm alexandrite laser, have also been reported to be effective in the treatment of verruca. We share our experience of successfully treating recalcitrant plantar warts using long-pulsed 1064-nm Nd:YAG, alone or in combination with the alexandrite laser.

      • ERADication of EDEM1 occurs by selective autophagy

        Sujin Park,Insook Jang,Jin Won Cho,Jürgen Roth 한국당과학회 2013 한국당과학회 학술대회 Vol.2013 No.1

        Misfolded and misassembled glycoproteins are retained in the endoplasmic reticulum (ER) where they are exposed to the protein folding machinery and protein quality control. The Unfolded Protein Response is activated in response to an accumulation of unfolded or misfolded proteins in the lumen of the ER. Eventually, misfolded and mis-assembled glycoproteins are targeted for degradation by a process called ER-associated protein degradation (ERAD). EDEM1 is an ERAD component that interacts with misfolded luminal glycoproteins and routes them for dislocation. This is followed by their ubiquitination and proteasomal degradation. Although EDEM1 was proposed to be a lectin–like protein and to react with Man8GlcNAc2 oligosaccharides of glycoproteins, still very little is known about the turnover and degradation mechanism of EDEM1 and how this relates to the fate of its substrates. Previously, we reported that EDEM1 exits the ER by a vesicular non-COPII-mediated mechanism and becomes rapidly degraded by basal autophagy. Here, we provide detailed insight into the mechanism by which EDEM1 becomes degraded. After its dislocation to the cytosol, EDEM1 is apparently making complexes with the selective autophagy receptors p62, NBR1 and Alfy. We observed co-distribution of EDEM1 and selective autophagy receptors by double and triple confocal laser scanning immunofluorescence. By quantifying the relationship of EDEM1 and the selective autophagy receptors as visualized by confocal laser scanning immunofluorescence and double immunogold electron microscopy, dramatical changes were observed in HepG2 cells. Following inhibition of autophagy by wortmannin, the number and size of cytoplasmic clusters composed of EDEM1 and the selective autophagy cargo receptors dramatically increased and this aggregate formation was independent of the activity of HDAC6. We observed that deglycosylation of EDEM1 occurred by the action of the cytosolic peptide N-glycanase since treatment with inhibitors resulted in a strong increase in the amount of glycosylated EDEM1. Inhibition of cytosolic peptide N-glycanase also inhibited wortmannin-induced aggregation of EDEM1 and its complex formation with p62. This indicates that deglycosylation of EDEM1 is a prerequisite for subsequent ubiquitination and interaction with selective autophagy receptors. This demonstrates that the ERAD component EDEM1 itself undergoes ERAD involving selective autophagy

      • KCI등재

        A Descriptive and Statistical Analysis of Old English Compounds

        Sujin Park 한국영어학학회 2018 영어학연구 Vol.24 No.1

        This paper aims at providing a descriptive and statistical analysis of Old English (OE) nominal, adjectival, and verbal compounds on the basis of the exhaustive data (9,875 in total) retrieved from the OE dictionary, Bosworth and Toller. Compounding was one of productive operations of OE word formation. Accordingly, OE compounds have received much attention from a number of earlier works (Quirk and Wrenn 1989, Lass 1994, Görlach 1997, Mitchell and Robinson 2001, Baugh and Cable 2002, Hogg 2002, Kastovsky 1985, 1992, 2002, 2006, 2009, among others). These previous (descriptive) studies, however, do not provide a statistical analysis based on exhaustive data; their research scope of OE compounds is limited to some typical types and a few examples. In this study, I attempted to elaborate the previous works by adding or reclassifying the compounds morphological types and semantic patterns, and by presenting the distribution of each compound type. The main result of this extensive research can be twofold. First, the distribution shows that the number of OE nominal, adjectival, and verbal compounds is 8,034 (81.35%) 1,674 (16.95%), and 167 (1.69%) respectively. Second, OE compounds can have much more varied morphological subtypes (42) and semantic subpatterns (100) than those that have been proposed by earlier works. I argue that the findings are meaningful and significant for the field of OE compounding, as they show not only qualitative but also quantitative aspects of OE compounds for the first time.

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