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Mahuya Pakhira,Subhajit Ghosh,Surajit Ghosh,Dhruba P. Chatterjee,Arun K. Nandi 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.112 No.-
Biocidal and anti-fouling properties in the same polymeric membranes are important in biomedical fieldfor their capability to protect serious infection and filtration of biological molecules. For this purpose wereport random graft copolymer of poly(vinylidene fluoride) (PVDF-graft-poly(tBAEMA-ran-OEGMA,PVBO) membranes showing both antifouling and antibacterial activity. The PVBO copolymer is synthesisedusing ATRP technique and the polymer membranes are produced by breath figure (PVBO-1) andphase inversion (PVBO-2) techniques. The former shows well-developed hexagonal pores (diameter15 ± 3.5 nm), and good hydrophilicity (contact angle 41.3). PVBO-1 membrane exhibits good antifoulingproperty for both lysozyme and BSA solutions. Antimicrobial activity measured from agar diffusionmethod indicates that PVBO-1 shows a large zone of inhibition in case of gram-negative E coli andgram-positive S. aureus bacteria, whereas PVBO-2 and its HCl treated state (PVBO-3) membranes exhibitonly a moderate zone of inhibition. The MBC and MIC values indicate that the synthesized membranesare bactericidal in nature and not bacteriostatic. Live and dead cell assay indicates that PVBO-1 can significantlyinhibit growth of bacteria even at high bacteria concentration confirming high antimicrobialactivity. MTT assay suggests PVBO-1 is non-cytotoxic to mammalian cells and co-culturing activity resultsuggests high cellular selectivity of PVBO-1.
Roychowdhoury Satyabrata,Bhakta Subhajit,Mahapatra Manas Kumar,Ghosh Saptarshi,Saha Sayantika,Konar Mithun Chandra,Sarkar Mihir,Nandi Mousumi 대한소아청소년과학회 2022 Clinical and Experimental Pediatrics (CEP) Vol.65 No.7
Background: During the coronavirus disease 2019 (COVID-19) pandemic, lung ultrasonography (US) has been gaining importance in pediatric intensive care and emergency settings for the screening, diagnosis, and monitoring of pulmonary pathology.Purpose: To describe the pattern of lung US changes in patients with COVID-19 pneumonia and its potential role in monitoring ventilated patients.Methods: This prospective observational study included children aged 1 month to 12 years with a confirmed diagnosis of COVID-19. Lung US was performed using a high-frequency linear probe (5–12 MHz) in all children with moderate/severe respiratory symptoms within 24 hours of admission and then daily until the patient required oxygen therapy. Lung involvement severity was assessed using lung US scores, while lung aeration improvement or deterioration was measured using lung ultrasound reaeration scores (LUSReS).Results: Of 85 children with moderate to severe disease, 54 with pulmonary disease were included. Of them, 50 (92.5%) had an interstitial pattern, followed by pleural line abnormalities in 44 (81.5%), reduced or absent lung sliding in 31 (57.4%), and consolidation in 28 (51.8%). A significantly higher lung US score (median, 18; interquartile range [IQR], 11–22) was observed in ventilated versus nonventilated patients (median, 9; IQR, 6–11). LUSReS improvement after positive end-expiratory pressure titration was positively correlated with improved dynamic lung compliance and oxygenation indices and negatively correlated with the requirement for driving pressure. Successful weaning could be predicted with 100% specificity if loss of LUSReS ≤ 5.Conclusion: Interstitial syndrome, fragmented pleural line, and subpleural microconsolidation were the most prevalent lung US findings in children with COVID-19 pneumonia. Thus, lung US may have the ability to monitor changes in lung aeration caused by mechanical ventilation and predict its successful weaning in children with COVID-19.
Non-destructive Characterization of MSW-contaminated Surface Soils by EDXRF and low-Z Particle EPMA
Shila Maskey,Chul-Un Ro,Dhrubajyoti Gupta,Jyotsnamayee Chatterjee,Rita Ghosh,Ajoy Kumar Mitra,Subinit Roy,Manoranjan Sarkar,Subhajit Chowdhury,Asit Bhowmik,Ujjal Mukhopadhyay 한국대기환경학회 2010 한국대기환경학회 학술대회논문집 Vol.2010 No.5월