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Exercise and Physical Activity in Mental Disorders: Clinical and Experimental Evidence
Zschucke, Elisabeth,Gaudlitz, Katharina,Strohle, Andreas The Korean Society for Preventive Medicine 2013 Journal of Preventive Medicine and Public Health Vol.46 No.suppl
Several epidemiological studies have shown that exercise (EX) and physical activity (PA) can prevent or delay the onset of different mental disorders, and have therapeutic benefits when used as sole or adjunct treatment in mental disorders. This review summarizes studies that used EX interventions in patients with anxiety, affective, eating, and substance use disorders, as well as schizophrenia and dementia/mild cognitive impairment. Despite several decades of clinical evidence with EX interventions, controlled studies are sparse in most disorder groups. Preliminary evidence suggests that PA/EX can induce improvements in physical, subjective and disorder-specific clinical outcomes. Potential mechanisms of action are discussed, as well as implications for psychiatric research and practice.
Modeling and investigation start-up procedures of a combined cycle power plant
Alobaid, F.,Postler, R.,Strohle, J.,Epple, B.,Kim, H.G. Applied Science Publishers 2008 APPLIED ENERGY Vol.85 No.12
This study describes the particular development and investigation of a static and dynamic simulation model and its application to improve the start-up process of a combined cycle power plant. Generally, the power plant system and control design mean highly complex interactivities. The dynamic simulation models using powerful computers are effective tools for studying and understanding the operating characteristics of power plants to meet and improve the design, control strategy and operational requirements. The heat recovery steam generator (HRSG) is modeled by using commercial simulation software named advanced process simulation software (APROS). The HRSG model includes an advanced control philosophy and turbine bypass systems to have a high level of accuracy, especially during hard transients. The comparison between the simulation results and measured data is documented. The received results proved and embodied that the simulation is both very reliable to estimate the real HRSG dynamic behaviour and capable to predict the operational processes. Through a parametric study, the start-up time will be reduced while keeping the life-time consumption of critically stressed components under control.
Deanna Taiym,Matthew Cowan,Brad Nakamura,Hooman Azad,Anna Strohl,Emma Barber 대한부인종양학회 2023 Journal of Gynecologic Oncology Vol.34 No.5
Objective: To determine the effectiveness of implementing an Enhanced Recovery After Surgery (ERAS) program, including continuous intraoperative and postoperative intravenous (IV) lidocaine infusion, on perioperative opioid use. Methods: This was a single-institution retrospective pre- post- cohort study. Consecutive patients undergoing planned laparotomy for known or potential gynecologic malignancy were identified after implementation of an ERAS program and compared to a historical cohort. Opioid use was calculated as morphine milligram equivalents (MMEs). Cohorts were compared using bivariate tests. Results: A total of 215 patients were included in the final analysis, 101 patients received surgery before ERAS implementation and 114 received surgery after. A reduction in total opioid use was observed in ERAS patients compared with historical controls (MME 26.5 [9.6–60.8] versus 194.5 [123.8–266.8], p<0.001). Length of stay (LOS) was reduced by 25% in the ERAS cohort (median 3 days, range 2–26, versus 4 days, range 2–18; p<0.001). Within the ERAS cohort, 64.9% received IV lidocaine for the planned 48 hours, and 5.6% had the infusion discontinued early. Within the ERAS cohort, patients who received IV lidocaine infusion used less opioids compared to those who did not (median 16.9, range 5.6–55.1, versus 46.2, range 23.2–76.1; p<0.002). Conclusion: An ERAS program including a continuous IV lidocaine infusion as the opioid-sparing analgesic strategy was noted to be safe and effective, leading to decreased opioid consumption and LOS compared with a historic cohort. Additionally, lidocaine infusion was noted to decrease opioid consumption even among patients already receiving other ERAS interventions.