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Ganesan Rethinam,Anand Duraiswamy,G. Dayanand Reddy,P. Elankani,Sampath Kundrapakkam Srinivasan 경희대학교 융합한의과학연구소 2022 Oriental Pharmacy and Experimental Medicine Vol.22 No.2
Acute kidney injury (AKI) is described as a disorder with a sudden loss of kidney function. AKI is also attributed to several aetiologies such as diabetes, cardiac problems, etc. Developing a therapy for AKI is challenging due to its complex pathophysiology. The present study investigated the effect of Sphaeranthus amaranthoides Burm f. aqueous extract, a Siddha Kalpha drug, against gentamicin-induced AKI. Animals were initially pre-administered with different concentrations of S. amaranthoides and later induced with gentamicin on the 8th day. Biochemical, anti-inflammatory and antioxidant markers were analysed. Further, HRLCMS analysis was carried out to identify the bioactive components. Components including myo-inositol, traumatic acid, rosmarinic acid, etc. were identified. In the animals induced with gentamicin, KIM1, LDH, GGT, creatinine, BUN and electrolytes were elevated in both serum and urine, while noted within normal range in S. amaranthoides pre-administered groups. Histopathology analysis revealed prevention of necrosis, tubular epithelial cell degeneration and glomerular congestion in S. amaranthoides administered animals. Lipid peroxidation, KIM1, Cystatin C, TNFα, IL6 and NFκB were within normal range in tissues. Thus, it is evident that S. amaranthoides is effective in protecting kidney damage and treating AKI. Further studies will be conducted to analyse the pathways resurrecting kidney damage.
Comparative Study on the Wear Behavior of Long and Short Glass Fiber Reinforced Plastics
V. Srinivasan,R. Karthikeyan,G. Ganesan,B. Asaithambi 대한금속·재료학회 2010 METALS AND MATERIALS International Vol.16 No.2
In recent years, the fiber reinforced composites have been used more in tribological applications where the sliding surfaces requires a high wear resistance and a low co-efficient of friction. The growth of GFRP is significantly higher than that of steel. No engineer or designer can ignore the growth of GFRP, but the decision to use a new material is difficult, yet important. The comparative tribological performance of short and long glass fiber–epoxy composites, under varying load and sliding velocities, is reported in this investigation. Besides conventional weighing, the coefficient of friction, contact temperature, and wear rate were determined. The worn surfaces of the specimens were examined by a Scanning Electron Microscope (SEM). The wear mechanisms and the transitions that govern the tribological behavior of the composites between them are discussed in detail. It was found that the epoxy reinforced with a long glass fiber exhibited a reduced wear rate than the short glass fiber.
Lim, Jong Min,Ganesan, Karthik,Sung, Young Mo,Srinivasan, Alagar,Chandrashekar, Tavarekere K.,Kim, Dongho The Royal Society of Chemistry 2014 Chemical communications Vol.50 No.33
<P>The role of thiophene bridges in determining the photophysical properties of bridged core-modified hexaphyrins is investigated. Depending on the substituted chalcogen atoms and conjugational perturbation across the thiophene bridges, the bridged core-modified hexaphyrins reveal unique photophysical properties.</P> <P>Graphic Abstract</P><P>The role of thiophene bridges in determining the photophysical properties of bridged core-modified hexaphyrins is investigated. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4cc00309h'> </P>
Nanocrystalline cerium oxide coated fiber optic gas sensor
B. Renganathan,D. Sastikumar,A. Chandra Bose,R. Srinivasan,A.R. Ganesan 한국물리학회 2014 Current Applied Physics Vol.14 No.3
A clad-modified fiber optic sensor with nanocrystalline CeO2 is proposed for gas detection. As-prepared and annealed CeO2 (500 C) samples have been used as gas sensing media. The spectral characteristics of the fiber optic gas sensor are studied for various concentrations of ammonia, ethanol and methanol gases (0e500 ppm). The sensor exhibits linear variation in the spectral peak intensity with the gas concentration. The characteristics of the sensor are also studied for gas selectivity. The time response characteristics of the sensor are reported.
Haladhara NAIK,Guinyun KIM,Annareddy Venkat Ramann REDDY,Devesh RAJ,Duc Khue PHAM,In Soo KO,Kwangsoo KIM,Moo-Hyun CHO,Srinivasan GANESAN,남궁원,Young Do OH 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.52 No.3
The post-neutron-emission mass yield distribution and the photo-neutron cross-section σ (γ,3n)) of 209Bi with 65-MeV bremsstrahlung have been determined using an off-line gamma-ray spectrometric technique in the test electron linac at Pohang Accelerator Laboratory. The post-neutron mass yield distribution in 65-MeV bremsstrahlung induced fission of 209Bi is symmetric with average mass around 103 and a FWHM of 22 mass units, which is higher than the literature value of 19 mass units in the energy range of 28 -- 40 MeV. The increasing trend of the FWHM of the post-neutron mass yield distribution with increasing breamsstrahlung energy has been explained from the point of view of the increase in the multi-chance fission probabilities with increasing excitation energy. The (γ,3n) reaction cross-section is determined for the first time. It was also calculated using the TALYS code and was found to be in good agreement with the experimental value. The post-neutron-emission mass yield distribution and the photo-neutron cross-section σ (γ,3n)) of 209Bi with 65-MeV bremsstrahlung have been determined using an off-line gamma-ray spectrometric technique in the test electron linac at Pohang Accelerator Laboratory. The post-neutron mass yield distribution in 65-MeV bremsstrahlung induced fission of 209Bi is symmetric with average mass around 103 and a FWHM of 22 mass units, which is higher than the literature value of 19 mass units in the energy range of 28 -- 40 MeV. The increasing trend of the FWHM of the post-neutron mass yield distribution with increasing breamsstrahlung energy has been explained from the point of view of the increase in the multi-chance fission probabilities with increasing excitation energy. The (γ,3n) reaction cross-section is determined for the first time. It was also calculated using the TALYS code and was found to be in good agreement with the experimental value.