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RISS 인기검색어
- 검색키워드
- 저자 : Sowndhararajan, Kandhasamy (검색결과 32 건)
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Sowndhararajan,Kandhasamy,Kang, Sun-Chul 경북대학교 농업생명과학대학 2012 Current Research on Agriculture and Life Sciences Vol.30 No.2
In the present study, acetone extract and sub-fractions of Albizia amara stem bark were evaluated for their free radical potential. The results showed that the crude extract and all the fractions exhibited antioxidant and free radical scavenging activities under different in vitro assays. Among the different fractions, the ethyl acetate fraction exhibited higher DPPH and ABTS radical scavenging activities than the standard quercetin. A. amara stem bark might be valuable source of natural antioxidants that could be used for medicinal and food applications.
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Sowndhararajan, Kandhasamy,Kim, Songmun MDPI 2016 Scientia pharmaceutica Vol.84 No.4
<P>The influence of fragrances such as perfumes and room fresheners on the psychophysiological activities of humans has been known for a long time, and its significance is gradually increasing in the medicinal and cosmetic industries. A fragrance consists of volatile chemicals with a molecular weight of less than 300 Da that humans perceive through the olfactory system. In humans, about 300 active olfactory receptor genes are devoted to detecting thousands of different fragrance molecules through a large family of olfactory receptors of a diverse protein sequence. The sense of smell plays an important role in the physiological effects of mood, stress, and working capacity. Electrophysiological studies have revealed that various fragrances affected spontaneous brain activities and cognitive functions, which are measured by an electroencephalograph (EEG). The EEG is a good temporal measure of responses in the central nervous system and it provides information about the physiological state of the brain both in health and disease. The EEG power spectrum is classified into different frequency bands such as delta (0.5–4 Hz), theta (4–8 Hz), alpha (8–13 Hz), beta (13–30 Hz) and gamma (30–50 Hz), and each band is correlated with different features of brain states. A quantitative EEG uses computer software to provide the topographic mapping of the brain activity in frontal, temporal, parietal and occipital brain regions. It is well known that decreases of alpha and beta activities and increases of delta and theta activities are associated with brain pathology and general cognitive decline. In the last few decades, many scientific studies were conducted to investigate the effect of inhalation of aroma on human brain functions. The studies have suggested a significant role for olfactory stimulation in the alteration of cognition, mood, and social behavior. This review aims to evaluate the available literature regarding the influence of fragrances on the psychophysiological activities of humans with special reference to EEG changes.</P>
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Sowndhararajan, Kandhasamy,Deepa, Ponnuvel,Kim, Minju,Park, Se Jin,Kim, Songmun MDPI 2017 Scientia pharmaceutica Vol.85 No.3
<P>A number of <I>Angelica</I> species have been used in traditional systems of medicine to treat many ailments. Especially, essential oils (EOs) from the <I>Angelica</I> species have been used for the treatment of various health problems, including malaria, gynecological diseases, fever, anemia, and arthritis. EOs are complex mixtures of low molecular weight compounds, especially terpenoids and their oxygenated compounds. These components deliver specific fragrance and biological properties to essential oils. In this review, we summarized the chemical composition and biological activities of EOs from different species of <I>Angelica</I>. For this purpose, a literature search was carried out to obtain information about the EOs of <I>Angelica</I> species and their bioactivities from electronic databases such as PubMed, Science Direct, Wiley, Springer, ACS, Google, and other journal publications. There has been a lot of variation in the EO composition among different <I>Angelica</I> species. EOs from <I>Angelica</I> species were reported for different kinds of biological activities, such as antioxidant, anti-inflammatory, antimicrobial, immunotoxic, and insecticidal activities. The present review is an attempt to consolidate the available data for different <I>Angelica</I> species on the basis of major constituents in the EOs and their biological activities.</P>
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Sowndhararajan Kandhasamy,Damodaran, Puthanveettil Naray 계명대학교 자연과학연구소 2015 Quantitative Bio-Science Vol.34 No.1
The experiments were carried out to study the effect of AMF and biocontrol agents on improving plant health and suppressing plant diseases in cotton cultivar, MCU-5-VT. Inoculation of both AMF and Trichoderma reduced disease severity. Biochemical concentrations in plant tissues were significantly influenced by AMF and biocontrol agent inoculation. Higher biochemical concentrations with maximum accumulation of proteins, amino acids and phenols were observed in plants inoculated with the tested microorganisms. Defense related enzyme activity, peroxidase and phenyl alanine ammonia-lyase, increased with inoculation of both AMF and the pathogen. Generally enzyme activities reached their maximum at early stages of plant growth and were reduced subsequently. Soil microbial activity, measured in terms of soil respiration rate and dehydrogenase activity, increased significantly in inoculated soils.
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Sowndhararajan, Kandhasamy,Kang, Sun-Chul Institute of Agricultural Science and Technology 2012 慶北大農學誌 Vol.30 No.2
In the present study, acetone extract and sub-fractions of Albizia amara stem bark were evaluated for their free radical potential. The results showed that the crude extract and all the fractions exhibited antioxidant and free radical scavenging activities under different in vitro assays. Among the different fractions, the ethyl acetate fraction exhibited higher DPPH and ABTS radical scavenging activities than the standard quercetin. A. amara stem bark might be valuable source of natural antioxidants that could be used for medicinal and food applications.
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Sowndhararajan, Kandhasamy,Deepa, Ponnuvel,Kim, Minju,Park, Se Jin,Kim, Songmun Elsevier 2018 Biomedicine & pharmacotherapy Vol.97 No.-
<P><B>Abstract</B></P> <P> <I>Schisandra chinensis</I> fruits have been traditionally used for thousands of years in Korea, China and Japan to treat various ailments. The fruits contain a variety of bioactive metabolites, especially lignan components have been reported to have various biological activities and have potential in the treatment of numerous neurodegenerative diseases. The lignans from <I>S. chinensis</I> are mainly grouped under dibenzocyclooctadiene lignans. Previous studies have reported that the crude extracts and the isolated pure lignan components effectively protect the neuronal cell damage and significantly enhance the cognitive performances. The experimental findings support the extracts and lignan components from <I>S. chinensis</I> can be used as new therapeutic agents to treat various neurodegenerative diseases. In the current review, we highlight the lignans from <I>S. chinensis</I> as promising resources for the development of natural and effective agents for neuroprotective and cognitive enhancement effects. The lignan extracts and individual compounds from <I>S. chinensis</I> were summarized in relation to their neuroprotective and cognitive enhancement activities.</P>
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Kandhasamy Sowndhararajan,Perumal Siddhuraju,Sellamuthu Manian 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.2
Antioxidant potential and total phenolics content of 70% acetone extracts of the raw and processed seeds of Bauhinia vahlii were evaluated. The extract of raw seeds contained higher levels of total phenolics (30.8 g/100g) and tannins (19.6 g/100 g) compared to dry heated and soaking followed by autoclaving seed extracts. Extracts were screened for antioxidant and free radical scavenging activities using various chemical and in vitro model systems. In all the models, except DPPH radical scavenging activity,the extract from raw seeds manifested the strongest antioxidant activity than that from processed seeds. In β-carotene/linoleic acid emulsion system and superoxide scavenging activity, the raw seed extract registered more activity when compared to the standards (butylated hydroxyanisole and α-tocopherol). Whereas, the extract from dry heated seed exhibited higher DPPH• scavenging activity (IC50 70.77 μg/mL) than the raw seeds (IC50 74.4μg/mL). This study has to some extent validated the antioxidant potential of the seeds of B. vahlii.
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Antioxidant Activity of the Differentially Processed Seeds of Jack Bean (Canavalia ensiformis L. DC)
Kandhasamy Sowndhararajan,Perumal Siddhuraju,Sellamuthu Manian 한국식품과학회 2011 Food Science and Biotechnology Vol.20 No.3
Antioxidant activity of 70% acetone extracts of raw and processed seeds of Jack bean (Canavalia ensiformis L. DC) was evaluated by various in vitro antioxidant assays, including total antioxidant, free radical scavenging, reducing power, metal ion chelating, β-carotene/linoleic acid bleaching, and antihemolytic activities. The total phenolics and tannin contents were higher in the extract of seeds processed by autoclaving with 1% ash solution (3.2 and 1.6 g/100 g extract, respectively). In general, all the extracts of processed seeds exhibited higher activity in various antioxidant systems, when compared to raw seeds but significant differences were noticed between processing methods. The extract of seeds autoclaved with 1% sugar solution showed higher DPPH radical scavenging activity (IC_50 10.6 mg/mL). Interestingly, the extract of dry heated seeds registered higher inhibition of hemolysis (76.1%) compared to standards butylated hydroxyanisole (BHA) (66.2%) and α-tocopherol (59.3%)at the concentration of 500 μg/mL.
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Kandhasamy Sowndhararajan,Souren Paul,권기석,황철원,강선철 한국식품과학회 2014 Food Science and Biotechnology Vol.23 No.3
The anti-ulcer activity of polyamine extract(PAE) of salt stressed and sprouted soybean seeds againstethanol-induced gastric damage was investigated in a ratmodel. The contents of the polyamines putrescine (20.11%),spermidine (9.46%), and spermine (2.79%) in PAE weredetermined using HPLC. The anti-ulcer activity of theextract was compared with the effects of the reference drugomeprazole. Pre- and post-administration of PAE at doses of10+10, 20, and 20+20mg/kg of body weight in conjunctionwith ethanol administration significantly protected ethanolinducedgastric damage. The levels of superoxide dismutaseand glutathione in stomach tissues were significantlychanged, when compared with an ethanol control group. Polyamine extract exhibited high protective effect againstulcer lesions and could be used to develop new anti-ulcerdrugs.
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