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      • 치과기공실의 작업공정별 소음에 관한 연구

        조수열,남상룡 효성여자대학교 부설 한국환경위생연구소 1992 환경위생연구 Vol.2 No.1

        본 연구는 치과기공실의 작업부서별, 1인작업시의 소음도를 조사하여 기본자료로 하고 복합공정시의 소음을 측정하여 70 dB이상의 소음 노출시간을 조사함으로서 전체 치과기공실의소음도를 추정하고, 치과기공실의 소음이 치과기공사에게 정신적, 정서적 , 생리적으로 어떠한영향을 미치는가를 설문조사하여 소음에 노출되어 있는 치과기공소의 환경위생 관리와 건강장해를 예방하기 위한 기초자료를 얻고자하는데 그 목적이 있으며 그 결과는 다음과 같다. 1. 작업부서변 1인 공정시 소음도는 각 작업부서별 모두 연마작업시 높은 수치를 나타냈으며, 그 정도는 70 dB이상이다. 2. 작업부서별 복합공정시 공정별 소음도는 1인 작업공정시보다 전체적으로 소음발생이증가하였는데, 소음도의 차이는 연마시보다 조용한 작업공정 시가 최소한 10 dB이상으로더 큰 차이가 나타났다. 3. 작업부서별 소음 노출시간은 80 dB이상에서는 복합공청시 도재기공부서(150분), 국부의치(120분), 관교의치기공(100분), 총의치기공(80분) 순으로 나타났다. 4. 작업실의 시간대변 소음정도는 연마작업시는 대부븐이 80 dB이상이고 Wax작업시는대부분이 75 dB이하로 나타났다. 5. 설문조사에서 치과기공사의 심리적 상태는 기공실 소음으로 인하석 거의 매일 짜증난다(14%), 가끔씩 짜증난다(29%)로 나타났고 정서적 불안감도 화가 잘 난다(19%)로나타났다. 6. 소음이 치과기공사의 신체에 미치는 영향은 기공일을 하는 동안 위장병에 대해서는위산과다 39%, 위궤방 11%, 위염 5%, 십이지궤양 3% 순으로 나타났고, 심장이 약한것 같다가 32%로 나타났다. 7. 소음이 치과기공사의 청력에 미치는 영향은 약해진다가 39%, 보통이다 33%, 정상이다14%로 나타났다. 치과기공실에서 발생되는 소음에 의해 치과기공사들이 심리적, 신체적으로 큰 영향을 받는것으로 나타났으므로 치과기공실의 작업환경관리에 대해 보다 많은 관심이 요구되며, 소음의발생을 줄일 수 있는 지속적인 연구가 요망된다. Degree of noise by personal dental laboratory working process anddegree of noise by complex dental laboratory working process were measuredseparately. The time of exposure to noise greater than 70 dB estimated on thebasis of afore-medntioned information. Questionarire were employed to investi-gate the mental, emotional and physiological effects of noise on dental techni-cians. The purpose of this study was to provide basic information on keepingdental technicians who are exposed to noise pollution in good working conditionand good health. Results obtained are as follows ; 1. Polishing process in each working part showed high degree of noisegreater than 70 dB in terms of degree of noise by personal working. 2. Degee of noise by complex working process in each workong part wasgreater than that of personal working process. 3. Time of exposure to noise complex working process the part of porcelain150 min., partial denture 120 min., crown and bridge 100 min., full denture80 min. 4. Degree of noise by time in dental laboratory was 80 dB in general forpolishing process and below 75 dB for waxing process. 5. Effects of noise on mental and emotional state of dental technicians she-wed that they felt irritated every day(14% ), irritated once in a while(39% ) andeasily get med(19% ). 6. Effects of noise on heart and stomach were hyper-gastric acid(38% ) ,gastric ulcer(11% ), gastritis(5% ), deuodenal ulcer(3% ) and weak hert function(32% ). 7. Effects of noise on the hearting ability were weak(39% ), moderate(33% )and normal(14% ). Data presented in this study demonstrated that noise in the dental laboratoryexerts profound effect on detal technicians mentally, physiologically and emotio-nally. In light of the above results, therefore, it appears advisable to devote subs-tantial interests on the management of working condition and put further(conti-nuing) effeorts in the ivestigation for reducing noise problem.

      • 香辛料의 成分이 白鼠의 物質代謝에 미치는 影響

        曺秀悅 嶺南大學校 環境問題硏究所 1982 環境硏究 Vol.2 No.1

        This study was attempted to investigate the effect of garlic, ginger and black pepper added to food on the nutrient metabolism of rats. Fifty-six males of Lewis strain, 80±5g, were divied into 7 groups and each group was fed ad libitum for 5 weeks. Garlic at 1% caused a significant increase in net weight gain, but garlic at 5% did not. Garlic caused a significant increase in the weight of kidney and spleen, but a significant decrease in the weight of heart. Ginger caused a decrease in net weight gain and the weight of spleen. Black pepper caused a significant decrease in net weight gain, but a significant increase in the liver weight. Rats given feed containing garlic and ginger showed significant decrease in serum cholesterol and glucose levels, but in black pepper did not. Feeding of spices such as garlic, ginger and black pepper did not affected in the serum proteins, albumin, globulin and electrolytes(??, ??, ?? and P). Garlic and ginger caused a decrease in serum pre-ß-and ß-lipoprotein cholesterol while increasing the α-lipoprotein fraction, but black pepper did not.

      • 카페인添加飼料가 白鼠의 血淸 및 肝臟脂質成分에 미치는 影響

        曺秀悅,安泰英 嶺南大學校 環境問題硏究所 1981 環境硏究 Vol.1 No.1

        The purpose of this study was to investigate the effect on the storing up the lipid in the body influenced by caffeine and on the lipid ingredients in the serum and the liver influenced by the diet mixed with caffeine and protein using the hypocholesterolemic effect of protein. The experimental method was based on using the albino rats of Wistar strain. Forty-eight albino rats which weighed 80 ±5g were divided by two grojups. one of which was not containing caffeine diet group, the other of which was containing caffeine diet group. Again, not containing caffeine diet group were divided by three groups, each of which was 10%, 20% and 30% of protein level respectively ; low protein diet, basal diet, high protein diet. Containing caffeine diet group was also divided by three groups, each of which 10%, 20%, and 30% of protein level and was added 0.25% of caffeine diet equally ; low protein diet contained caffeine, basal diet contained caffeine, high protein diet contained caffeine. All was raised by ad libitum feeding method for four weeks. After that, each group was measured as contrasted by the net gain of weight, the weight of the various internal organs and cholesterol, triglyceride, free fatty acid in serum respectively and also cholesterol, triglyceride, free fatty acid in the liver respectively. The results were followings ; 1. In the net gain of weight, high protein diet group was the highest and low protein diet contained caffeine group was the lowest. Containg caffeine diet groups showed generally the low tendency. 2. In the weight of the liver, low prtein diet contained caffeine group was the highest and containing caffeine diet groups showed generally the high tendency. In the weight of kidney, heart and spleen, the result was as same as that of the liver. 3. In contents of cholesterol and free fatty acid in serum, low protein diet contained caffeine diet group was the highest. In contents of triglyceride in serum, high protein diet group was the highest. 4. In contents of cholesterol triglyceride and free fatty acid in the liver, low protein diet contained coffeine diet group was the highest.

      • 천연자원의 간기능 보호 효과에 관한 연구 : Benzo(a)pyrene에 의해 유도된 간기능 장해에 미치는 울금의 효과 The Effect of Curcumae Rhizoma on Benzo(a)pyrene Induced Hepatotoxicity

        조수열,윤수홍,이윤경,이정숙 효성여자대학교 부설 한국환경위생연구소 1992 환경위생연구 Vol.2 No.1

        우리의 생활환경중 어디에나 존재하는 강력한 간독성유발물 benzo(a)pyrene으로 유도된 간장해에 대한 울금의 예방 및 치료효과를 관찰하여 다음과 같은 결과를 얻었다. 1. 울금 추출물 급여는 B(a)P투여로 증가한 혈청 ALT 와 ALP혈청을 현저히 회복시켰으나 혈청 AST활성은 회복시키지 못하였고, 혈청LDH의 활성은 전 실험군 사이에 유의적인 변화가 없었다. 2. 간조직 및 혈청중의 지질함량 변동은 B(a)P단독투여로 인한 유의성 있는 변화에 대해 단지 혈청중의 HDL-cholesterol과 total cholesterol 함량만이 울금 추출물 투여에 의해 정상범위로 회복되었다. 3. 간조직중의 glutathione 함량은 울금 추출물 투여로 B(a)P 단독투여군에 비해 유의성 있는 회복을 보였고, 과산화지질 함량은 B(a)P 단독투여로 인해 유의성 있게 증가하였으나 울금추출물 급여가 이런 증가를 회복시키지는 못했다. This study was performed to investigate the effect of Curcumae Rhizoma extract on the hepatic detoxication when benzo(a)pyrene, a hepatotoxi-cant, was administrated. The results were as followed : 1. The markedly increased enzyme activities(ALT, ALP) were decreasedby administration the Curcumae Rhizoma extract. 2. Serum HDL-cholesterol and total cholesterol contents were normal inthe Curcumae Rhizoma extract groups. 3. Liver glutathione content were decreased by administration the CurcumaeRhizoma extract. 4. It tended that the curative effects were better than the protective effectsof the Curcumae Rhizoma extract.

      • 白鼠의 無機質代謝에 미치는 칼슘과 마그네슘의 影響 : 2. Effect on the sodium, potassium, copper and iron metabolism in tissues 2. 組織 중의 Na, K, Cu 및 Fe 代謝에 미치는 影響

        曺秀悅,鄭在洪 嶺南大學校 環境問題硏究所 1982 環境硏究 Vol.2 No.1

        This experiment was undertaken to investigate the effect of the diet containing two levels of calcium(0.5%, 0.1%) and magnesium (0.04%, 0.0002%) on the sodium, potassium, copper and iron concentrations of kidney, liver and femur in rats. Thirty-two males of Sprague-Dewley strain, 70-80g, were divided into 4 groups and each group(8 rats)was fed ad libitum for 4 weeks. sodium and potassium in the liver, kidney and femur were determined by flame spectrophotometry. Copper and iron in liver, kidney and femur were determined by atomic absorption spetrophotometry. The results obtained are summarized as follow. Net weight gain and feed efficiency ratio were decreased in the calcium and magnesium-deficient groups. The weight of liver, heart and kidney generally showed increasing tendency in the calcium-deficiency group. The weight of iung was showed to decreased in the magnesium-deficient group compared to the control group. The sodium and potassium concentrations of liver, kidney, and femur are the dietary calcium and magnesium levels did not tend to affect on the sodium concentration of kidney and potassium concentration fo femur and liver. But sodium content of liver tended to be significantly increased in the magnesium deficient-group. The potassium concentration of kidney in the deficient-groups(II,III,IV) tended to be greatly increased as compared with the control group. The sodium concentration of femur in the deficient-groups(II, III, IV) was slightly lower as comapared with that of the control group. Both copper and iron contents of the kidney, liver, and femur were the highest in kidney and the dietary Ca and Mg levels were not effected on the copper content of liver. The iron concentration of liver in the Ca-deficient group tended to be greatly higher than that of the other groups. The copper contents of kidney in the Mg-deficient group was lower than that of the other groups, and the iron contents in the deficient groups(II, III, IV) lower as compared with the control group. The copper content of the femur tended to be lower at the deficient levels(II, III, IV) and the copper concentration at the Mg-deficient level was greatly increased as compared with that of the control group.

      • 白鼠의 無機質代謝에 미치는 칼슘과 마그네슘의 影響 : 칼슘과 마그네슘 代謝에 미치는 影響

        曺秀悅,鄭在洪 嶺南大學校 環境問題硏究所 1981 環境硏究 Vol.1 No.1

        This experiment was undertaken to investigate calcium and magnesium metabolism of rats fed the diet containing two levels of calcium(0.05%, 0.1%) and magnesium (0.04%, 0.0002%). Thirty-two males of Sprague-Dewley strain, 70-80g, were divided into 4 groups and each group (8 rats) was fed ad libitum for 4 weeks. Calcium and magnesium in sera, tissues and femurs were determined by atomic absorption spectrophotometry. The results obtained are summarized as follow. Net weight gain and feed efficiency ratio were decreased in the calcium and magnesium-deficient groups. The weights of liver, heart and kidney generally showed increasing tendency in the calcium-deficient group. Lung was showen to decrease in the magnesium-dificient group compared to the control group. Serum cholesterol showed increasing tendency in the groups of deficiency in calcium and calcium plus magnesium. Serum clacium and magnesium decreased in the groups of deficiency in calcium, magnesium and calcium plus magnesium. Calcium contents in liver and kindey were not affected by the dietary clacium and magnesium levels. Calcium contents in kidney were significantly increased in the groups of deficiency in magnesium levels. Calcium contents in kidney were significantly increased in the groups of deficiency in magnesium and calcium plus magnesium. Calcium contents in femur were decreased in the Calcium-deficient group, whereas magnesium contents in liver were increased in the magnesium-deficient group. Calcium and magnesiumexcretion to feces and urine was decreased in the calcium and magnesium deficient groups respectively.

      • 白鼠의 血淸成分에 미치는 芥子의 泳響

        曺秀悅,金德鎭,金鍾碩 嶺南大學校 環境問題硏究所 1985 環境硏究 Vol.5 No.2

        검수삭제 The changes of body weight, degestion and absorption rate, the weight of several kinds of the internal organs, serum protein, cholesterol, sugar, and the inorganic ingredients induced by mustard in rats were investigated. The increase of body weight lowered in the additional group of 1% and 5% mustard and the effect was related to dose of mustard. The efficiency of feed lowered in the additional group of 5%. Kidney weight was decreased by the increasing quantity of mustard. The spleen weight lowered only the additional group of 1%. There were little change in other internal organs. The total protein in the serum was increased in the additional group of 1% and 5% of mustard, and albumin increased in the additional group of 1% mustaed, but there were a tendency of a decrease more or less in the additional group of 5% mustaed, α₁-Globulin was decreased in the additional group of 1%, but α₂-globulin increased more or less in the additional group of 5% mustaed. On the other hands, ??-globulin showed a remarkable increase by the more additional quantity of mustard. The cholesterol in the serum showed on increase in the additional group of 5% mustard, and glucose a little increase in the additional group of 1% and 5% mustard. Serum Na was increased in the additional group of 1% mustard but not in 5% group.

      • Butane gas가 흰쥐 혈청과 조직의 Lactatedehydrogenase 및 Cholinesterase에 미치는 영향

        윤수홍,박은주,조수열,최현태 한국환경독성학회 1991 환경독성보건학회지 Vol.6 No.2

        Acute poisoning with organic solvents and other volatile compounds now usually follows deliberate inhalation (volatile substance abuse) or ingestion of these compounds. The effect of butane gas inhalation was analyzed for serum, liver, brain, lung and muscle. And the observations are revealed on rat cholinesterase activity, lactatedehydrogenase activity and electrophoretic pattern of lactatedehydrogenase isozyme. The results are as follows: 1. The rat cholinesterase activity on serum, liver and muscle show the decreased by increasing of inhalation time of butane gas in particular the lung cholinesterase activity was greatly affected. 2. Butane gas inhalation brought out the lactatedehydrogenase activity increased of the serum and the tissues and had an important effect especially in both the liver and muscle lactatedehydrogenase activities. 3. Each tissue was found to have a characteristic distribution of lactatedehydrogenase isozymes on celluloseacetate electrophoresis and the development of inhalation time is shown the disappearance and diffusion of band. The toxicity of butane gas inhalation was most prominence in the liver and lung toxicity was occurred also.

      • Benzo(a)pyrene에 의해 유도된 간기능 장해에 미치는 쑥의 효과

        윤수홍,조수열,박은주,김성중 한국환경독성학회 1992 환경독성보건학회지 Vol.7 No.1

        Mugwort has been used as a Korean folk medicine in treating liver diseases acting as an analgesics, sedative, diuresis, choleretics. This study was perfomed to evaluate the effect of mugwort extracts on the changes of enzyme activities, lipid accumulation of the serum and liver, when hepatotoxicity was induced by benzo(a)pyrene. The results are as follows: 1. Mugwort water extract administration prevented the increase of serum and liver AST, ALT, LDH, γ-GTP, liver ALP activities and bilirubin content caused by B(a)P injection. 2. The increase of serum and liver ALT, LDH, γ-GTP, serum AST activities and liver bilirubin contents in B(a)P treated group were decreased by mugwort methanol extract treatment. 3. Serum and liver total cholesterol, phospholipid, triglyceride level and serum HDL-cholesterol level were increased by B(a)P treatment. After combined treatment of mugwort water and methanul extracts, these lipid content were significantly decreased. 4. The hepatotropic effect of mugwort water extract and after-treatment against B(a)P induced hepatotoxicity was superior to that of methanol extract and pretreatment.

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