Distribution of Genetic Variants in Korean Soybeans

Kitae Song,Jeong Hoon Kim,Gi Yong Yoon,Hyo Chul Kim,Seungho Shin,Won Cheol Yim,Kyung-Hee Kim,Byung-Moo Lee 한국작물학회 2015 Korean journal of crop science Vol.60 No.2

Next generation sequencing technologies provide opportunities to reveal the genetic variants and differentially expressedgenes. The genetic variants are closely relevance to understanding of genes and phenotypic differences related to agronomic characteristics among cultivars. In this study, we conducted RNA-seq using two Korean soybean accessions, including Daewon and Hwangkeum, by using next generation sequencing against Williams 82 genome as reference. A number of variants such assingle nucleotide variants (SNV), multiple nucleotide variants (MNV), insertion/deletion (InDel) and replacement, was 34,411 and 55,544 in Daewon and Hwangkeum, respectively. Among these variants, 9,611 nonsynonymous variants were detected within 4,290 genes in Daewon and 13,225 non-synonymous variants were located on 5,672 genes in Hwangkeum. The distribution of nonsynonymous variants and expression values of genes can serve as invaluable resource for genotyping and study of traits within genes for soybean improvements.

독일 바이마르 공화국 초기 노동시장에 대한 국가간섭주의의 형성과정

송기철(Gi Chul Song) 한국독일사학회 2002 독일연구 Vol.- No.3

Der Beitrag beschäftigt sich mit der staatlichen Arbeitsmarktpolitik in der Demobilmachungszeit nach dem Ersten Weltkrieg in Deutschland. Dabei werden die arbeitsmarktpolitischen Regulierungsmaßnahmen des Demobilmachungsamtes(DMA) bei der Überleitung der Kriegswirtschaft in die Friedenswirtschaft untersucht, um zu zeigen, wie es in der revolutionären Umbruchsphase 1918/19 in Deutschland zu einem Durchbruch des arbeitsmarktpolitischen Staatsinterventionismus kam. In der Konstituierungsphase der Weimarer Republik nach dem Ersten Weltkrieg wurden zum Schutz der abhängigen Arbeitnehmer vor existenziellen Risiken der Arbeitslosigkeit Einrichtungen wie das staatliche Arbeitslosenunterstützungssystem, das umfassende öffentliche Arbeitsnachweiswesen und die finanziellen und organisatorischen Institutionen zur Arbeitsbeschaffung geschaffen. Dies bedeutet die endgültige Durchsetzung der einheitlichen staatlichen Arbeitsmarktpolitik in Deutschland, die mit den Regulierungsversuchen auf dem Arbeitsmarkt im Rahmen der Kriegswirtschaft eingeleitet worden war. Die These des Autors ist, daß nicht allein die gewaltigen Veränderungen m den Arbeitsmarktstrukturen im Zuge der kriegswirtschaftlichen Entwicklung, sondern vielmehr der Wandel in den Beziehungen der Arbeitsmarktparteien, der im Herbst 1918 mit dem Zusammenbruch des Wilhelminischen Deutschlands vollzogen wurde, die grundlegende Neuordnung der staatlichen Arbeitsmarktpolitik in den Anfangsjahren der Weimarer Republik zur Folge hatte. Die industriellen und gewerkschaftlichen Spitzenorganisationen vereinbarten mit der Unterzeichnung des sogenannten Zentralarbeitsgemeinschafts-Abkommens vom 15. November 1918 eine umfassende Zusammenarbeit auf dem Gebiet der Sozial- und Wirtschaftspolitik und insbesondere ein gemeinsames Programm für die Übergangswirtschaft, dessen Kern die Errichtung des Demobilmachungsamtes war. Das DMA führte vielfältige und komplexe arbeitsmarktpolitische Maßnahmen durch, die kurzfristig auf die Stabilisierung der durch die Kriegsniederlage und die politischen Erschütterungen äußerst angespannten Arbeitsmarktlage und längerfristig auf die strukturelle Neuordnung der Arbeitsmarktverhältnisse abzielten. Die arbeitsmarktpolitischen Maßnahmen des DMA trugen entscheidend dazu bei, den gefährlichsten sozialen Sprengsatz in der deutschen Revolution 1918/19 zu entschärfen, indem sie zur Bekämpfung der Massenarbeitslosigkeit beitrugen. Hatte sich der arbeitsmarktpolitische Staatsinterventionismus in der Weimarer Republik aufgrund des Klassenkompromißes von Kapital und Arbeit 1918/19 herausgebildet, so bestand auch seine Hauptfuntkion darin, die antagonistischen Interessen von Kapital und Arbeit auf dem Arbeitmarkt durch Eingriffe und Vermittlungen des Staates zum Ausgleich zu bringen. In diesem ambivalenten Kompromißcharakter lagen letztlich auch die Möglichkeiten und die Grenzen des arbeitsmarktpolitischen Staatsinterventionismus in den zwanziger Jahren in Deutschland begründet.

Evaluation of Blast Resistance Gene Distribution in landrace Rice(Oryza sativa L.) of Korea

Myung-Chul Lee,Jae Young Song,Gi-An Lee,Hong-Jae Park,Do Yoon Hyun,Jeong-Ro Lee,Chang Young Kim,Young Chan Cho,Im Soo Choi,Yeon-Gyu Kim 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07

During the last decade, considerable progress has been made to understand the molecular mechanisms of M. grisea infection in rice plants and 10 rice blast R genes have been identified and characterized via map-based cloning methods. In case of rice germplasm, the genetic backgrounds of each germplasm accessions are not uniform and the evaluation for pathogenicity is difficult. To solve these problems, we applied the single resistance gene markers to rice germplasm accessions. A molecular survey was conducted to identify the presence of major blast resistance (R) gene in 363 accessions of Korea landrace rice germplasm. The results revealed that the resistance gene Pik-p (100%), Pib (98%), Pi-d(t)2 (98%) and Piz (76%) were widely observed in tested rice germplasm, but Pita-2, Pik and Pi39 gene were identified in less than 10 accessions. Most of landrace contain the four or five different resistant genes, but these results was not consist of field nursery screening. 13 accessions were shown the blast resistance in field nursery screening and Pik-p, Pib, Pi-d(t)2 and Piz genes were observed in these accessions. The evaluation results of blast resistance genes in rice germplasm will help in breeding of multi disease resistant varieties.

임신중기 원인불명의 융모성 성선자극호르몬 상승과 임신예후와의 연관성

송경철(Kyung Chul Song),이지성(Ji Sung Lee),임승욱(Seung Ug Lim),엄기남(Gi Nam Eom),강철규(Cheol Gyu Kang),최유덕(Yu Duk Choi),김석영(Sug Young Kim),황병철(Byoung Chul Hwang),김광준(Kwang Jun Kim),이의돈(Eui Don Lee),박찬용(Chan Yong 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.8

N/A Objective : The purpose of this study was to compare the neonatal and maternal infectious morbidity between single and multiple courses of antenatal betamethasone treatment in patients with preterm premature rupture of membranes. Methods : One hundred seventy patients who delivered neonates between 28 and 34 weeks' gestation after preterm premature rupture of membranes from January 1992 to July 2000 were reviewed retrospectively. Patients were divided into 3 groups on the basis of the following betamethasone exposures: (1) none (control subjects), (2) betamethasone 4 mg IM, IV simultaneously and then 4 mg IV q 8 hours for 24 hours (single course) and (3) weekly administration after initial single course (multiple courses). All included patients received prophylactic antibiotics for group B streptococci. The statistical analyses were done using χ2 test, Fisher's exact test and one way analysis of variance (ANOVA). Multiple logistic regression analysis was performed to determine the confounding effect of the multiple variables those were considered as risk factors for neonatal sepsis. Results : This study included 67 patients in the control group, 60 patients in the single course group, and 43 patients in the multiple courses group. The latency (p=.0001) was significantly longer in the patients exposed to multiple course than the patients in the control group and those in the single course group. No significant difference was demonstrated in the incidence of neonatal sepsis (p=.881) and postpartum endometritis (p=.619) among the three groups. Neonatal sepsis was significantly associated with clinical chorioamnionitis (p=.022). Conclusion : According to our data, multiple courses of antenatal betamethasone treatment in patients with preterm premature rupture of membranes was not associated with the increased incidence of neonatal sepsis and postpartum endometritis.

Blast Resistant Genes Distribution and Resistance Reaction to Blast in Korean Landraces of Rice (Oryza sativa L.)

Song, Jae Young,Lee, Gi-An,Choi, Yu-Mi,Lee, Sukyeung,Lee, Kwang Beom,Bae, Chang-Hyu,Jung, Yeonju,Hyun, Do-Yoon,Park, Hong-Jae,Lee, Myung-Chul The Plant Resources Society of Korea 2014 한국자원식물학회지 Vol.27 No.6

Rice blast (Magnaporthe oryza B.) is one of the most important diseases in rice that causing great yield losses every year around the world. It is important to screen valuable genetic resources for improving blast resistance. This study was conducted to identify the blast resistance in 279 Korean rice landraces using blast nursery tests and isolate inoculum screening. The results showed that 11 landrace accessions found to be resistant to rice blast in blast nursery and inoculation screening tests and the degree of lesions in most accessions showed that they were susceptible to reactions. In order to find the distribution of blast resistant genes, a molecular survey was conducted to identify the presence of major blast resistance (R) gene in 279 Korean landraces. The results revealed that their frequency distribution was Pik-m (36.2%), Piz (25.4%), Pit (13.6%), and Pik (10%). Besides, the frequency distribution of Piz-t, Pii, Pik-m/Pik-p, Pi-39(t), Pib, Pi-d(t)2, Pita/Pita-2 and Pi-ta genes were identified as less than 10%. The results did not consist with the reactions against blast diseases between genotypes and phenotypic part of the nursery tests and isolate inoculation. For concluding these results, we used genome-wide SSR markers that have closely been located with resistance genes. The PCoA analysis showed that the landrace accessions formed largely two distinct groups according to their degree of blast resistance. By comparing genetic diversities using polymorphic information contents (PIC) value among the resistant, total and susceptible landraces, we found that PIC values decreased in four SSR markers and increased in six markers in the resistant accessions, which showed contrary to total and susceptible groups. These regions might be linked to resistance alleles. In this study, we evaluated the degree of blast resistance and the information about the distribution of rice blast resistant genes in Korean rice landraces. This study might be the basis for association analysis of blast resistance in rice.

Protective role of NecroX-5 against neomycin-induced hair cell damage in zebrafish

Song, Jae-Jun,Chang, Jiwon,Choi, Jungim,Im, Gi Jung,Chae, Sung Won,Lee, Seung Hoon,Kwon, Soon-Young,Jung, Hak Hyun,Chung, Ah-Young,Park, Hae-Chul,Choi, June Springer-Verlag 2014 Archives of toxicology Vol.88 No.2

Comparison between Cadaveric Whole Liver and Live Donor Partial Liver Transplantation in High Risk Patients with MELD Score More than 40

( Chul Soo Ahn ),( Shin Hwang ),( Ki Hun Kim ),( Deok Bok Moon ),( Tae Yong Ha ),( Gi Won Song ),( Dong Hwan Jung ),( Gil Chun Park ),( Sung Gyu Lee ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: Two types of grafts are possible for liver transplantation. Cadaveric whole liver graft(CLT) gives sufficient volume with suboptimal function. live donor partial liver graft(LDLT) has optimal function with volume limitation. Athough, the results from both type of graft are similar, but whole liver grafts are preferred then partial liver grafts if the ithrecipient,s condition is very poor. So we analysed the results of whole and partial liver graft transplantation which recipient's MELD score was more than 40. Methods: From Dec. 1994 to Dec. 2016, 5241 liver transplantation were done in Asan Medical Center. 269 recipient's MELD score were more than 40. Among them, 44 cases were excluded due to slavage transplantation, multiple organ transplanatation, split or two donor transplantation and retranspantation and 225 cases were analysed. Results: CLT were 84 cases. LDLT were 141 cases( right lobe graft 125, left lobe graft 16 ). the GRWR were 2.20(1.16 -3.40) in CLT group and 0.98( 0.67 -.158) in LDLT group. There's no difference in MELD score in both group( CLT 43.4 vs LDLT 44). In hospital mortality in CLD were 18 cases(21.4%), infection in 11, primary non function( PNF) in 2, intracranial hemorrhage(ICH) in 3 and stress induced cardiomyopathy in 1 and sever pulmonary failure in 1 case. mortality in LDLT group were 21 cases(14.9%), infection in 11, PNF in 5, ICH in 4, and acute hepatic arterial thrombosis in 1 case. There were no difference between both group in ICU stay and post operative hospital days and outpatient course. Conclusions: In conclusion, with precise selection and careful operation, LDLT can get comparable or better results to whole liver graft transplantation.

Use of Wastepaper for Developing Environment-friendly Shock-absorbing Materials

CHUL-HWAN KIM,DAE-BIN SONG,YOUNG-MIN LEE,JAE-OK KIM,GYEONG-YUN KIM,TAE-GI SHIN,CHONG-YAWL PARK 한국펄프·종이공학회 2006 한국펄프종이학회 기타 간행물 Vol.- No.-

Environment-friendly shock-absorbing materials were made of wastepaper such as old corrugated containers (OCC) and old newspapers (ONP) with a vacuum forming method. The plate-like cushioning materials made of OCC and ONP respectively by vacuum forming showed superior shock-absorbing properties with lower elastic moduli compared to expanded polystyrene (EPS) and pulp mold. Even though the plate-like materials had many free voids in their fiber structure, their apparent densities (?0.1 g/㎤) were a little higher than that of EPS (?0.03 g/㎤) and much lower than that of pulp mold (?0.3 g/㎤). However, the elastic moduli of the cushioning materials made of wastepaper were much lower than that of EPS or pulp mold. This finding implies that the cushioning materials made of OCC fibers containing more lignin than ONP show better shock-absorbing properties than ONP. Moreover, the cushioning materials made of OCC and ONP respectively showed greater porosity than pulp mold. The addition of cationic starch to the cushioning materials contributed to an increase in the elastic modulus to the same level as that of EPS. Furthermore, the deterioration in fiber quality by repeated use of wastepaper played a great role in improving shock-absorbing ability.

Prognostic impact of hepatitis b virus infection in patients with intrahepatic cholangiocarcinoma

Chul-Soo Ahn,Shin Hwang,Young-Joo Lee,Ki-Hun Kim,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Gil-Chun Park,Sung-Gyu Lee 한국간담췌외과학회 2016 한국간담췌외과학회 학술대회지 Vol.2016 No.4

Use of Waste Woods for Developing Environment-friendly Shock-absorbing Materials

CHUL-HWAN KIM,DAE-BIN SONG,YOUNG-MIN LEE,JAE-OK KIM,GYEONG-YUN KIM,TAE-GI SHIN,CHONG-YAWL PARK 한국펄프·종이공학회 2006 한국펄프종이학회 기타 간행물 Vol.- No.-

Environment-friendly shock-absorbing materials were made using a vacuum forming method from waste wood collected from local mountains in Korea. The waste wood was pulped by thermomechanical pulping. The TMP cushions showed superior shock-absorbing properties with lower elastic moduli compared to EPS and pulp mold. Even though the TMP cushions made using different suction times had many free voids in their inner fiber structure, their apparent densities were a little higher than EPS and much lower than pulp mold. The addition of cationic starch improved the elastic modulus of the TMP cushions without increasing the apparent density, which was different from surface sizing with starch. The porosity of the TMP cushions was a little greater than EPS and much less than pulp mold. Finally, the TMP cushions have great potential to endure external impacts occurring during goods distribution.