Evaluation and Comparation of a Novel Surgical Technique and Hemivertebra Resection to the Correction of Congenital Cervical Scoliosis in Lower Cervical and Cervicothoracic Spine

Shuo Cao,Xin Chen,Shengfa Pan,Yinze Diao,Yanbin Zhao,Tian Xia,Weishi Li,Feifei Zhou,Yu Sun 대한척추신경외과학회 2022 Neurospine Vol.19 No.4

Objective: To report concave-side distraction technique to treat congenital cervical scoliosis in lower cervical and cervicothoracic spine. To evaluate and compare clinical and radiographic results of this procedure with classic hemivertebra resection procedure. Methods: This study reviewed 29 patients in last 13 years. These patients were divided into convex-side resection group (group R) and concave-side distraction group (group D). Radiographic assessment was based on parameter changes preoperatively, postoperatively and at last follow-up. Demographic data, surgical data and complications were also evaluated and compared between the 2 groups. Results: In group R, mean age was 8.9 ± 3.3 years and follow-up was 46 ± 18 months. Operation time and blood loss averaged 500 ± 100 minutes, 703 ± 367 mL. In group D, mean age was 9.9 ± 2.8 years and follow-up was 34 ± 14 months. Operation time and blood loss averaged 501 ± 112 minutes, 374 ± 181 mL. Structural Cobb angle was corrected from 29.4° ± 12.5° to 5.3° (2.1°–18.1°) (p = 0.001) and 33.7° ± 14.1° to 12.8° ± 11.4° (p < 0.001) in groups R and D. Compensatory Cobb angle had a spontaneous correction rate of 59.6% (40.0%–80.8%) and 59.7% ± 23.0% in groups R and D. Mandibular incline, clavicle angle and spine coronal balance were significantly improved at last follow-up in both groups. All correction rates were not statistically different between groups. However, group D had significant less blood loss (p < 0.001) and operation time (p = 0.004) per vertebra than group R. Seven patients developed C5 nerve root palsy and recovered by 6 months of follow-up. Conclusion: Both surgical procedures are safe and effective in correcting congenital cervical scoliosis. But concave-side distraction technique has less blood loss and time-consuming during surgery, which provides a better option for the treatment of congenital cervical scoliosis.

The development of rural endowment patterns in China

Shangping Ma,Shuo Ma,Qinglou Cao 전북대학교 산업경제연구소 2018 아태경상저널 Vol.10 No.2

Aging of the population has become a reality in China, and the problem of supporting old people becomes a critical problem needing immediate solutions, especially the raising problem of rural old-ages that has been increasingly serious, which has affected all aspects of social development. To have recognition of the status of rural endowment pattern is the critical point to explore the endowment pattern that is suitable for the rural endowment of China and to solve the problems of the rural old-age care. First, this paper reviews the theoretical research of rural endowment pattern, and then the status of existing family endowment pattern, institution endowment pattern and analyzed home-based endowment pattern of Chinese rural areas and the main existing problems. Finally, Then on the base of these, this paper studied the revolution and development direction of Chinese rural endowment pattern, and imagination on an endowment pattern that could meet the physical truths of Chinese rural areas was put forward to provide the reference for the optimization and innovation of rural endowment pattern of China.

The Interlaminar Mechanical and Impact Properties of Fibre Metal Laminates Reinforced with Graphene

Fanglin Cong,Shuo Wang,Linlin,Meng Cao,Zehui Jia,Zhiqiang Zhou,Xu Cui 한국섬유공학회 2022 Fibers and polymers Vol.23 No.5

Glass fibre aluminium laminate (Glare) is widely used in various fields because of its excellent performance. However, its properties can be further enhanced by adding nanofillers, such as graphene, to the matrix. Graphene is a costeffectivetoughening agent because of its excellent specific strength, economy and good compatibility. The interlaminarmechanical and dynamic impact properties of Glare were improved by uniformly dispersed graphene (0, 0.2, 0.3, 0.5 and1.0 wt%). The interlaminar mechanical properties (short beam shear and single lap test) of the graphene-modified (0.5 wt%)Glare were increased by 42.24 % and 25.65 %, respectively, compared with the pure epoxy resin matrix. At a graphenecontent of 1.0 wt%, the Charpy impact energy and strength increased by 163.58 % and 126.33 %, respectively, and reachedthe maximum value. The microscopic images and schematic diagrams illustrated the toughening mechanism of graphene,including the enhancement of the aluminium/resin and fibre/resin interfaces and the performance of the resin matrix. Thetoughening of the resin matrix was achieved through the formation of a mechanical linkage between the graphene and thematrix, which indicated that more time and energy would be required to destroy it.

Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps through toll-like receptor 4

Yang Liu,Xin Zhang,Shuo Chen,Jiazhong Wang,Shuo Yu,Yiming Li,Meng Xu,Harouna Aboubacar,Junhui Li,Tao Shan,Jixin Wang,Gang Cao 대한간학회 2022 Clinical and Molecular Hepatology(대한간학회지) Vol.28 No.3

Background/Aims: Binge drinking leads to many disorders, including alcoholic hepatosteatosis, which is characterized by intrahepatic neutrophil infiltration and increases the risk of hepatocellular carcinoma (HCC). Molecular mechanisms may involve the migration of bacterial metabolites from the gut to the liver and the activation of neutrophil extracellular traps (NETs). Methods: Serum samples from both binge drinking and alcohol-avoiding patients were analyzed. Mouse models of chronic plus binge alcohol-induced hepatosteatosis and HCC models were used. Results: A marker of NETs formation, lipopolysaccharide (LPS), was significantly higher in alcoholic hepatosteatosis and HCC patients and mice than in controls. Intrahepatic inflammation markers and HCC-related cytokines were decreased in mice with reduced NET formation due to neutrophil elastase (NE) deletion, and liver-related symptoms of alcohol were also alleviated in NE knockout mice. Removal of intestinal bacteria with antibiotics led to decreases in markers of NETs formation and inflammatory cytokines upon chronic alcohol consumption, and development of alcoholic hepatosteatosis and HCC was also attenuated. These functions were restored upon supplementation with the bacterial product LPS. When mice lacking toll-like receptor 4 (TLR4) received chronic alcohol feeding, intrahepatic markers of NETs formation decreased, and hepatosteatosis and HCC were alleviated. Conclusions: Formation of NETs following LPS stimulation of TLR4 upon chronic alcohol use leads to increased alcoholic steatosis and subsequent HCC.

Crack Resistance and Strength Properties of Red Clay Modified with Lignocellulose and Guar gum

Hong-Yuan Fu,Guang-Tao Yu,Qian-Feng Gao,Ling Zeng,Shuo-Peng Cao 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.10

Desiccation cracking is a common problem of red clay under wet and dry conditions. The presence of cracks could reduce soil strength properties, which is the major reason for shallow failure of red clay slopes. This study aims to propose some additives to improve the crack resistance as well as the strength of red clay. To this end, three natural fibers and three natural gels were primarily selected to modify red clay. Desiccation crack tests were conducted to identify the best fiber and gel in terms of crack resistance. Then, direct shear tests and uniaxial tensile tests were performed on the soil specimens modified by the best fiber and gel to determine the optimal dosages regarding strength improvements. The results demonstrated that natural gels reduced the crack resistance of red clay, while natural fibers could enhance the crack resistance. Lignocellulose was the best additive in improving the crack resistance of red clay, and the modified effect was positively correlated with the fiber dosage. Adding 1.5% lignocellulose into red clay could reduce the crack rate from 2.19% to 0.30%, with a reduction of 0.86 times. The tensile strength, shear strength and its parameters of lignocellulose-modified red clay showed a trend of increasing first and then decreasing with increasing lignocellulose dosage. At the optimal lignocellulose dosage of 0.75%, the shear strength and tensile strength were increased by 44.63% and 18.21%, respectively. The strength of red clay modified by both lignocellulose and guar gum was positively correlated with the dosage of guar gum, and the desirable dosage of guar gum was 1.0%. In engineering practice, the wet red clay mixed with 0.75% lignocellulose and grass seeds can be employed as planting soil and is sprayed uniformly onto the slope surface after excavation using a spraying planting machine. To further improve the strength of the planting soil, 1.0% guar gum solution can be sprayed on the soil surface. The findings could provide useful guidance for the protection of red clay slopes.