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Shugang Zhang,Zhenji Zhang,Xiaolan Guan 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.1
Collaborative innovation is an important strategy choice of China nowadays, and also of the national universities. Using SOA architecture and cloud computing, we build an integration and optimizing allocation cloud platform of high quality teaching resources for universities-led collaborative innovation to meet the resource requirements of universities based on the analysis of basic concept, types, core process, and evolution characteristics of university-led collaborative innovation following the inherent laws of university-led collaborative innovation, and then analyze the construction concept, logical architecture and main functions of the platform,. Finally, we provide a series of suggestions to the relevant universities and government departments to effectively promote the smooth implementation of the university-led collaborative innovation activities and the integration and optimizing allocation cloud platform of high quality teaching resources for university-led collaborative innovation.
Shugang Xi,Guihua Zhou,Xuexin Zhang,Wenjie Zhang,Lu Cai,Chunyan Zhao 생화학분자생물학회 2009 Experimental and molecular medicine Vol.41 No.8
Total aralosides of Aralia elata (Miq) Seem (TASAES) from Chinese traditional herb Longya Aralia chinensis L was found to improve cardiac function. The present study was to determine the protective effects of TASAES on diabetic cardiomyopathy, and the possible mechanisms. Therefore, a single dose of streptozotocin was used to induce diabetes in Wister rats. Diabetic rats were immediately treated with low, medium and high doses of TASAES at 4.9, 9.8 mg/kg and 19.6 mg/kg body weight by gavage, respectively, for eight weeks. Cardiac function was evaluated by in situ hemodynamic measurements, and patch clamp for the L-type Ca2+ channel current (ICa2+-L) and transient outward K+ channel current (Ito). Histopathological changes were observed under light and electron microscope. The expression of pro-fibrotic factor, connective tissue growth factor (CTGF) was monitored using immunohistochemistry staining. Compared with diabetic group, medium and high doses, but not low dose, of TASAES showed a significant protection against diabetes-induced cardiac dysfunction, shown by increased absolute value of left ventricular systolic pressure (LVSP) and maximum rates of pressure development (±dp/dtmax), and enhanced amplitude of ICa2+-L (P < 0.05). Histological staining indicated a significant inhibition of diabetes-caused pathological changes and up-regulation of CTGF expression (P < 0.05). The results suggest that TASAES prevents diabetes- induced cardiac dysfunction and pathological damage through up-regulating ICa2+-L in cardiac cells and decreasing CTGF expression. Total aralosides of Aralia elata (Miq) Seem (TASAES) from Chinese traditional herb Longya Aralia chinensis L was found to improve cardiac function. The present study was to determine the protective effects of TASAES on diabetic cardiomyopathy, and the possible mechanisms. Therefore, a single dose of streptozotocin was used to induce diabetes in Wister rats. Diabetic rats were immediately treated with low, medium and high doses of TASAES at 4.9, 9.8 mg/kg and 19.6 mg/kg body weight by gavage, respectively, for eight weeks. Cardiac function was evaluated by in situ hemodynamic measurements, and patch clamp for the L-type Ca2+ channel current (ICa2+-L) and transient outward K+ channel current (Ito). Histopathological changes were observed under light and electron microscope. The expression of pro-fibrotic factor, connective tissue growth factor (CTGF) was monitored using immunohistochemistry staining. Compared with diabetic group, medium and high doses, but not low dose, of TASAES showed a significant protection against diabetes-induced cardiac dysfunction, shown by increased absolute value of left ventricular systolic pressure (LVSP) and maximum rates of pressure development (±dp/dtmax), and enhanced amplitude of ICa2+-L (P < 0.05). Histological staining indicated a significant inhibition of diabetes-caused pathological changes and up-regulation of CTGF expression (P < 0.05). The results suggest that TASAES prevents diabetes- induced cardiac dysfunction and pathological damage through up-regulating ICa2+-L in cardiac cells and decreasing CTGF expression.
Shugang Pan,Ning Zhang,Yongsheng Fu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.3
In this paper, we report a facile strategy to design and prepare reduced graphene oxide (rGO) supported MoS2 nanoplatelet (MoS2/rGO) via a solvothermal co-assembly process. It is found that in the as-obtained MoS2/rGO nanocomposite, MoS2 possesses unique platelet structure and rGO is exfoliated due to the in situ growth of MoS2 nanoplatelet, leading to a large specific surface area, facilitating rapid diffusion of lithium ions. The nanocomposite is used as a promising anode material for lithium-ion batteries and displays a high initial charge capacity (1382 mA h g -1), excellent rate capability and cycling stability. The remarkable lithium storage performance of MoS2/rGO nanocomposite is mainly ascribed to the inherent nanostructure of the MoS2, and the synergistic effect between rGO nanosheets and MoS2 nanoplatelets.
Evolution Mechanism of Information Industry Ecological Security
Xiaolan Guan,Menggang Li,Shugang Zhang 보안공학연구지원센터 2015 International Journal of Security and Its Applicat Vol.9 No.8
The Information Industry Ecological Security is a combination of security and dynamic development. This paper analyzes the evolution mechanism of Information Industry Ecological Security from the perspective of evolution driving force, evolution process and so on using the theories and methods of Ecology and Synergetics systematically, and take China’s Information Industry Ecological Security as an example of empirical research, then provided a range of effective policy suggestions for relevant Chinese government departments to control and guide China's Information Industry Ecological Security.