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Optogenetics Applications for Treating Spinal Cord Injury
Aftab Ahmad,Sadia Ashraf,Shoji Komai 대한척추외과학회 2015 Asian Spine Journal Vol.9 No.2
Cases of spinal cord injury (SCI) are increasing all over the world; and in USA alone, there are 273,000 patients, which not only leads to morbidity and mortality but also results in a great economic burden. Many approaches are being used at the pre-clinical and clinical level to treat SCI including therapeutic agents, surgical decompression, stem cell therapy etc. Recently, a new approach called optogenetics has emerged in which light sensitive proteins are used to switch neurons on and off, and this approach has great potential to be used as therapy due to its specificity and rapid response in milliseconds. Few animal studies have been performed so far in which the respiratory and bladder function of rats was restored through the use of optogenetics. On the basis of promising results obtained, in the future, this approach can prove to be a valuable tool to treat patients with SCI.
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Perceptions of Research Excellence in Thailand and Japan
Kasama Kongsmak,Punchalee Pungpit,Mitsunobu R. Kano,Shoji Komai,Wibool Piyawattanametha,Orakanoke Phanraksa 과학기술정책연구원 2013 STI Policy Review Vol.4 No.2
This paper explores how research excellence is perceived among researchers in Thailand and Japan with an aim to explore whether there are any new indicators that could later be proposed and adopted as criteria of excellence. Based on a questionnaire survey, the findings reflect ideas and viewpoints that could be found among researchers in both countries. Creative researchers are crucial to a strong national research and innovation system. Institutions should provide an environment or incentives based on research performance for their researchers to flourish and be productive. For decades, bibliometrics have been used to evaluate individual research performance for its easy approach and faster speed than a qualitative assessment would warrant. Nonetheless, there have been a number of studies on research performance evaluating systems that point out how a purely bibliometric approach is inadequate in summarizing the quality of the scientific performance. The pressures on researchers today influence their thinking and oppose their creativity. To investigate the perception of research excellence, three key research questions were set in this study: what counts as excellence, how to measure excellence, and how to support excellence. The findings confirm that traditional granting criteria that frames an idea of excellence remain valid, but they also suggest novel criteria be considered and prioritized. This paper argues that the existing evaluating system is insufficient for unleashing the curiosity and creativity of researchers and fostering excellence. In the final section, the paper discusses factors that contribute to scientific creativity that we should not overlook.
ScienceON
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