http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Shirazy, Najmeh Hadizadeh,Ranjbar, Bijan,Hosseinkhani, Saman,Khalifeh, Khosrow,Madvar, Ali Riahi,Naderi-Manesh, Hossein Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.4
Bacterial luciferase is a heterodimeric enzyme, which catalyzes the light emission reaction, utilizing reduced FMN (FMNH2), a long chain aliphatic aldehyde and $O_2$, to produce green-blue light. This enzyme can be readily classed as slow or fast decay based on their rate of luminescence decay in a single turnover. Mutation of Glu175 in $\alpha$ subunit to Gly converted slow decay Xenorhabdus Luminescence luciferase to fast decay one. The following studies revealed that changing the luciferase flexibility and lake of Glu-flavin interactions are responsible for the unusual kinetic properties of mutant enzyme. Optical and thermodynamics studies have caused a decrease in free energy and anisotropy of mutant enzyme. Moreover, the role of Glu175 in transition state of folding pathway by use of stopped-flow fluorescence technique has been studied which suggesting that Glu175 is not involved in transition state of folding and appears as surface residue of the nucleus or as a member of one of a few alternative folding nuclei. These results suggest that mutation of Glu175 to Gly extended the structure of Xenorhabdus Luminescence luciferase, locally.
Diagnostic Accuracy of Magnetic Resonance Imaging versus Clinical Staging in Cervical Cancer
Shirazi, Ahmad Soltani,Razi, Taghi,Cheraghi, Fatemeh,Rahim, Fakher,Ehsani, Sara,Davoodi, Mohammad Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14
Background: Cervical cancer is the third most common gynecological cancer and a widespread malignancy in women, accounting for a large proportion of the cancer burden in developing countries. We compared accuracy of MRI staging with clinical staging and also concordance between the two methods for newly diagnosed patients with cervical cancer, using clinical staging as the reference. Materials and Methods: This prospective study was conducted on 27 newly diagnosed patients with cervical cancer from Imam Khomeini hospital from June 2012 to Feb 2014. New cases of cervical cancer with positive PAP test were staged separately with a clinical exam based on the FIGO system by a gynecologist, oncologist and also with MRI by an expert radiologist. Then we compared the predicted stage for each patient with the two methods. Results: Based on clinical staging 9 patients (33%) were observed at stage 1. MRI staging was in coordination with clinical staging in eight of them and for one patient MRI accorded stage 2B (88% concordance). Conclusions: MRI is a reliable noninvasive method with high accuracy for cervical cancer staging. Also presently it is easily obtainable, so we recommend using this technique along with clinical examination for staging cervical cancer patients. We also recommend to radiologists and residents of radiology to get experience with this method of staging.
Shirazi, Muhammad Faizan,Kim, Pilun,Jeon, Mansik,Kim, Chang-Seok,Kim, Jeehyun Elsevier 2018 Optics and laser technology Vol.101 No.-
<P><B>Abstract</B></P> <P>We developed a tunable laser diode for an optical coherence tomography system that can perform three-dimensional profile measurement using an area scanning technique. The tunable laser diode is designed using an Eagleyard tunable laser diode with a galvano filter. The Littman free space configuration is used to demonstrate laser operation. The line- and bandwidths of this source are 0.27 nm (∼110 GHz) and 43 nm, respectively, at the center wavelength of 860 nm. The output power is 20 mW at an operating current of 150 mA. A step height target is imaged using a wide-area scanning system to show the measurement accuracy of the proposed tunable laser diode. A TEM grid is also imaged to measure the topography and thickness of the sample by proposed tunable laser diode.</P> <P><B>Highlights</B></P> <P> <UL> <LI> High power free space broad-bandwidth tunable laser diode is developed. </LI> <LI> A simple Littman free space cavity is utilized with galvano-mirror scanner. </LI> <LI> Large field-of-view with no mechanical scanning can be imaged using the laser diode. </LI> <LI> A VLSI standard height target is imaged using the proposed tunable laser diode. </LI> <LI> Cross-sectional and three-dimensional images show the effectiveness of the system. </LI> </UL> </P>
Shirazi, Abolfazl,Mirshams, Mehran The Korean Society for Aeronautical and Space Scie 2014 International Journal of Aeronautical and Space Sc Vol.15 No.2
The pyramidal reaction wheel arrangement is one of the configurations that can be used in attitude control simulators for evaluation of attitude control performance in satellites. In this arrangement, the wheels are oriented in a pyramidal configuration with a tilt angle. In this paper, a study of pyramidal reaction wheel arrangement is carried out in order to find the optimum tilt angle that minimizes total power consumption of the system. The attitude control system is analyzed and the pyramidal configuration is implemented in numerical simulation. Optimization is carried out by using an iterative process and the optimum tilt angle that provides minimum system power consumption is obtained. Simulation results show that the system requires the least power by using optimum tilt angle in reaction wheels arrangement.
Shirazi, Muhammad Faizan,Wijesinghe, Ruchire Eranga,Ravichandran, Naresh Kumar,Kim, Pilun,Jeon, Mansik,Kim, Jeehyun Elsevier 2018 Optics and lasers in engineering Vol.110 No.-
<P>In this study, the industrial inspection of optical thin film on touch screen panels was demonstrated using line field spectral domain optical coherence tomography. The conventional Fourier domain optical coherence tomography system requires a single scanner for two-dimensional cross-sectional images and two scanners for volumetric images. Our developed line field spectral domain optical coherence tomography has the advantage of needing only a single scanner for volumetric images, while two-dimensional cross-sectional images are obtained by the parallel acquisition of an illuminated line on a sample using an area camera. Further, the image acquisition speed was enhanced by implementing a high speed camera (340 frames per seconds) with improved quantum efficiency at near infrared region enabling two-fold frame rate. Cross-sectional and volumetric images were acquired to detect the internal sublayer defects in the optical thin films, which are difficult to observe using visual or machine vision-based inspection methods. The developed pseudo code for defect identification in optical thin films was well-utilized here for the defect inspection. The system characterization is demonstrated using United State Air Force (USAF) resolution target. The results indicate the possible application of the proposed system in touch screen panel inspection for the quality assurance of products at the consumer end.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Quality assessment of the optical thin films used for touch screen panel. </LI> <LI> Line illumination is utilized to get the cross-sectional information without scanner. </LI> <LI> The sublayer defects are detected using line field optical coherence tomography. </LI> <LI> A defect detection algorithm is developed for the quality assurance of optical thin films. </LI> <LI> Cross-sectional and three-dimensional images show the effectiveness of the system. </LI> </UL> </P>
Shirazi, Rahau S.,Ewert, Kai K.,Silva, Bruno F. B.,Leal, Cecilia,Li, Youli,Safinya, Cyrus R. American Chemical Society 2012 Langmuir Vol.28 No.28
<P>Environmentally responsive materials (i.e., materials that respond to changes in their environment with a change in their properties or structure) are attracting increasing amounts of interest. We recently designed and synthesized a series of cleavable multivalent lipids (CMVLn, with <I>n</I> = 2–5 being the number of positive headgroup charges at full protonation) with a disulfide bond in the linker between their cationic headgroup and hydrophobic tails. The self-assembled complexes of the CMVLs and DNA are a prototypical environmentally responsive material, undergoing extensive structural rearrangement when exposed to reducing agents. We investigated the structural evolution of CMVL–DNA complexes at varied complex composition, temperature, and incubation time using small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS). A related lipid with a stable linker, TMVL4, was used as a control. In a nonreducing environment, CMVL–DNA complexes form the lamellar (L<SUB>α</SUB><SUP>C</SUP>) phase, with DNA rods sandwiched between lipid bilayers. However, new self-assembled phases form when the disulfide linker is cleaved by dithiothreitol or the biologically relevant reducing agent glutathione. The released DNA and cleaved CMVL headgroups form a loosely organized phase, giving rise to a characteristic broad SAXS correlation profile. CMVLs with high headgroup charge also form condensed DNA bundles. Intriguingly, the cleaved hydrophobic tails of the CMVLs reassemble into tilted chain-ordered L<SUB>β′</SUB> phases upon incubation at physiological temperature (37 °C), as indicated by characteristic WAXS peaks. X-ray scattering further reveals that two of the three phases (L<SUB>βF</SUB>, L<SUB>βL</SUB>, and L<SUB>βI</SUB>) constituting the L<SUB>β′</SUB> phase coexist in these samples. The described system may have applications in lipid-based nanotechnologies.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/langd5/2012/langd5.2012.28.issue-28/la301181b/production/images/medium/la-2012-01181b_0001.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/la301181b'>ACS Electronic Supporting Info</A></P>
Ayaz, Shirazi Muhammad,Kim, Min Young Informa UK (TaylorFrancis) 2017 International journal of optomechatronics Vol.11 No.1
<P>This article describes the 3D handheld profiling system composed of a stereo camera and an illumination projector to collect high-resolution data for close range of applications. Visual navigation approach is either based on feature matching or on accurate target, and the target-based approach was found to be more accurate if the 3D object has less texture on its surface. Block matching algorithm was used to render the single-view 3D reconstruction. For multiview 3D modeling, coarse registration and final refinement of the point clouds using iterative closest point algorithm were utilized. The proposed approach yields good accuracy for multiview registration as demonstrated in the results of this research.</P>
Abolfazl Shirazi,Mehran Mirshams 한국항공우주학회 2014 International Journal of Aeronautical and Space Sc Vol.15 No.2
The pyramidal reaction wheel arrangement is one of the configurations that can be used in attitude control simulators for evaluation of attitude control performance in satellites. In this arrangement, the wheels are oriented in a pyramidal configuration with a tilt angle. In this paper, a study of pyramidal reaction wheel arrangement is carried out in order to find the optimum tilt angle that minimizes total power consumption of the system. The attitude control system is analyzed and the pyramidal configuration is implemented in numerical simulation. Optimization is carried out by using an iterative process and the optimum tilt angle that provides minimum system power consumption is obtained. Simulation results show that the system requires the least power by using optimum tilt angle in reaction wheels arrangement.