가자의 즉각형 알레르기 반응 억제 효과

엄용대,신민교,이영미,김형민,신태용,정종길,송호준 대한본초학회 2000 大韓本草學會誌 Vol.15 No.1

We investigated the effects of methanol extract of Fructus Chebula (MEFC) on local and systemic anaphylaxis. Passive cutaneous anaphylaxis inhibited to 61.42 12.8 % by oral administration of MEFC(I.0 glkg). MEFC inhibited compound 48/80-induced anaphylactic shock 100% with doses of 0.05-1.0 glkg . Administrations of MEFC (1.0 glkg) 60 min before, 5 min after, and 10 min after the compound 48/80 treatment were shown the mortality rates as 0%. MEFC (0.01-1.0 glkg) inhibited the histamine release significantly from the rat peritoneal mast cells by compound 48/80. These results indicate that MEFC inhibits mast cell mediated anaphylactic reactions by inhibition of mast cell degranulation in vivo and in vitro.

Casein micelle 의 조성에 관한 연구 : I. Micelle 크기 별에 따른 각 casein 의 구성비율 I. The relative amounts of individual caseins in the different casein micelles

김영교,신동철,전우민 한국낙농학회 1984 韓國酪農學會誌 Vol.6 No.1

本 實驗은 casein miceile의 크기에 따른 각종 casein의 構成成分을 究明하고자 超遠心分離機를 利用하여 casein micelle을 크기 別로 分類하고 DEAE-cellulose column chromatography를 이용하여 각 casein의 構成比率을 조사하였다. 그 結果를 要約하면 다음과 같다. 1. 脫脂乳를 100,000×g에서 각각 30分, 60分, 90分동안, 200,000×g에서 60分동안 遠心分離하였을 때 沈澱되는 casein micelle 量은 45.00%, 61.43%, 80.00% 및 95.00%였으며 沈澱되지 않는 serum casein量은 55.00%, 38.57%, 20.00% 및 5.00%였다. 2. 脫脂乳를 100,000×g에서 時間 差에 따라서 遠心分離하였을 때 각각 沈澱되는 casein micelle量은 10分間에는 全 casein量의 23.13%, 11∼30分間에는 30.26%, 31∼60分間에는 28.11%였으며, 60分問의 遠心分離에 의해서 沈澱되지 않는 serum casein은 17.79%였다. 3. 時問 差로 遠心分離하여 얻어진 casein micelle중 각 casein의 構成比率을 測定한 結果, α_s-casein, β-casein, κ-casein 및 γ-casein의 상대적인 量은 100,000×g, 10分의 pellet에서 각각 54%, 29%, 11% 및 6%였고, 100,000×g, 11∼30分의 pellet에서는 각각 54%, 28%, 13% 및 5%였고, 100,000×g, 31∼60分의 pellet에서는 각각 51%, 28%, 16% 및 5%로 나타났으며, serum casein은 44%, 29%, 19% 및 8%로 각각 나타났다. This experiment was carried out to study on the protein composition of casein micelles. Three micellar casein pellets and a serum casein were isolated at diferent time of ultracen trifugation. And the composition of individual caseins for the fractions was determined by DEAE-cellulose column chromatography. The results are summarized as follows: 1. When skimmilk was centrifuged for 30 min, 60 min and 90 min at 100,000g and for 60 min at 200,000g, the values for the sedimented casein micelles were 45.00%, 61.43%, 80.00% and 95.00% respectively and that of serum casein was 55.00%, 38.57%, 20.00% and 5.00% respectively. 2. When skimmilk was centrifuged for different time at 100,000g, the values for the sedimented casein micelles were 23.18% for 10 min.(pellet 1), 30.26% from 11 to 30 min.(pellet 2), 28.11% from 31 to 60 min.(pellet 3) and that of serum casein which was not sedimented at 60 min was 17.79% of the total casin. 3. The relative amounts of α_s-, β-, k- and γ-caseins in casein micelles obtained after different time of centrifugation were 54%, 29%, 11% and 8% in pellet 1, 54%, 28%, 13% and 5% in pellet 2, 51%, 28%, 16% and 5% in pellet 3,44%, 29%, 19% and 8% in serum casein respectively.

國産漢方藥用植物에 關한 調査硏究(Ⅰ) : 蘭草科를 中心하여

辛民敎 圓光大學校 基礎自然科學硏究所 1982 基礎科學硏究誌 Vol.1 No.1

全北特産 韓藥材에 의한 農家所得增大 方案 硏究 (I) : 韓藥材 栽培의 適地 選定을 위한 群小都市의 土壤 調査

辛民敎 한국전통의학연구소 1998 한국전통의학지 Vol.8 No.2

Studied the size of soil by land category to select places suitable for cultivating oriental medicines, the speciaity of Chollabuk-do Provincial Government and property and size of the centering aroung topsoil. And the results are summarized as follows. 1. The total size of the soil of Kimje-City, Namwon-City, Iksan City, Chonju-City, Jeongup-City including Kunsan-City totaled adout 3,079,663.7㎢. 2. As for land category, forestry was 40% of a total size as about 1,224,513.7㎢. Rice field was 31% of a total size as about 960,723.1㎢. Dry field was 10% of a total size as about 293,448.7㎢. Though grassland and orchard did not amount to 1% as about 9,716.5㎢ and 228.6㎢, respectively other kinds of soil were 19% as about 588,853.3㎢. 3. As for the property of soil, loam was 46% as about 1,432,133.9㎢. Sandy loam was 24% as about 727,811㎢. Silty loam was 20% as about 608,486.6㎢. Sandy clay loam was 3% as about 82,139.3㎢. Sandy soil of good quality Anlehmiger sand did not amount to 1% as about 3,980.0㎢. While other kinds of soil were about 7% as about 234,104.6㎢.

전통식물(傳統食物)이 건강에 미치는 영향

신민교 동아시아식생활학회 1996 동아시아식생활학회지 Vol.6 No.2

The Traditional Food mean the plants which bear nutritional function and of which purpose is keeping health. However, when it is used for protection or cure of disease, we can call them medicinal substances. Therefore medicine and eating are ultimately same. Because of this point of a dietetic material medical foodstuff, if we obey Mother Nature and make a balanced diet, everyone will be able to enjoy a long life with keeping health.

韓醫學 敎育의 提高를 위한 韓醫科大學 敎科課程硏究

辛民敎 圓光大學校 韓醫學硏究所 1995 원광한의학 Vol.5 No.1

Recently, the internationalization and globalization is rapidly processed in the world and every field. With the trend, the education of Oriental Medicine is also reformed for the effective education and the current demand. In this paper, I suggested some opinions as a result of comparing the curriculum of Korea with that of China. 1. There are many subjects in the general course that has few relation with the major course. Accordingly, the unnecessary subjects should be substituted with the high-related subjects with the major. 2. The education of Chineses classics and classical literature of Korean Traditional Medicine should be strengthened for achieved the goal of education of Korean Traditional Medicine. 3. The education course should be established on the subjects suitable for the goal of education of Korean Traditional Medicine, not according to the faculty members. 4. The comparison of the education course between China and Korea suggested the necessity of establishing the characteristic education course peculiar to Orinetal Medicine. 5. The course of Keum-Guae-Yo-Raik, Pushing and pulling maneuver. Acute febrili disesase, and Bone and traumatology should be established. Also, the clinical base of modern medicine such as internal medicine, surgery, obstetrics and gynecology should be established for understanding generally modern medicine. 6. For the clinical training, now the theory and practice is carried out simultaneously. It is necessary to reform the course of clinical training like that of China. So at the last year of course, the collective practise is necessary and the time of clinical training should be increased.

대머리(白禿)의 豫防과 治療藥物에 關한 문헌적 연구

辛民敎 대한본초학회 1998 大韓本草學會誌 Vol.13 No.1

A bibliographical research on the herbal medicines used for treatment of baldheads found that there were 140 herbal medicines available for the treatment of hair loss; they included 75 vegetable medicines, 46 animal medicines, 10 mineral medicines, and 9 other medicines. The number of medicines that could treat baldheads with no new hair or with slow hair growth was found to be 24; they consisted of 18 vegetable medicines,5 animal medicines, I other medicine; but no mineral medicine was found for this type of treatment. In addition, the number of the medicines that could be applied to change the hair color from white to black was 12 and all of them were of vegetable nature. Overall, the study showed that there were a total of 159 herbal medicines related to the treatment of baldheads: they were classified into 97 vegetable medicines, 45 animal medicines, 10 mineral medicines, and 9 other medicines.

鄕藥集成方에 未收截된 鄕藥本草에 關한 調査硏究(植物編)

辛民敎 圓光大學校 1986 論文集 Vol.20 No.2

이 論文은 점차로 확대되는 韓方醫療需要에 따라서 이에 대한 韓藥材의 원만한 需給이 要請되고 있는 바, 우리나라에서 생산되고 있는 一定한 韓藥材를 除外하고는 많은 品種과 量을 輸入에 依存하는 관계로 外貨의 損失 및 藥價上昇으로 因한 國民保健向上에 莫大한 지장을 초래하고 있다. 그러므로 著者는 1433年 世宗命에 依해 集成出刊된바 있는 <鄕藥集成方> 中 鄕藥本草編의 植物藥 314種인 것을 현재까지 국내외로 硏究發明된 우리나라産 1,039種을 增補하므로서 總 1,353種을 臨床에 應用토록 하였다. The harmonious demand and supply of Oriental medicinal stuff is deeply required as the demand of Oriental medicine is gradually increasing. Recently, since many kinds and large quantity of Oriental medicinal stuff depend on imports except the small-scale production in our country, not only the heavy loss of foreign currency but also the rise in the price of Oriental stuff constitute obstacles to the elevation of national health. So, I intended the improvement of traditional medicine as a substitute the indigenous medicinal stuff for the imported Oriental medicinal stuff, supplementing the 1039 kinds proved as the indigenous herbs to the 314 kinds from the section of indigenous herbs in the Hyang-yak-jib-song-bang published by the order of Sejong the Great in 1433.

汚證 病因의 文獻的 考察

辛民敎 圓光大學校大學院 1981 學位論叢 Vol.7 No.-

In order to study "sweat-symptoms" I have covered 134 Oriental medical books as materials describing the symptoms. The result are as follows; (1) The first pathologic explanations about "sweat-symptoms" are written in The Yellow Emperor's Classic of Internal Medicine(黃帝內經) many times. (2) From the viewpoint of oriental medicine, sweat-symptoms are classified into 35 kinds. Among them, sweat, night-sweat, anhidrosis, forehead-sweat and sternum-sweat are important kinds. (3) Generally, yellowish and reddish-sweat are contained in sweat-symptoms. But I think it better for yellowish and reddish-sweat to be included in jaundice and blood part respectively according to Heuh-June's theory. (4) Abnormal Sweat, bed-sweat, anhidrosis, forehead-sweat can be found in feverish disease and various diseases. This explains that sweat is important symptoms. (5) The pathologic agents of sweat are generally due to 8 oriental diagnosis criteria, Ki and blood, 6 external evils, 7 excessive emotions and weakness-fullness of visera and bowls. (6) The causes of sweat are due to Yang-weakness, Ki-weakness in sequence. (7) The causes of bed-sweat are due to Yin-weakness, Ki-weakness, Blood-weakness and Kidney-weakness in sequence. (8) The origins of anhidrosis are due to External-fullness, Yang-fullness, Coldness-evil, Yin-fullness and Internal-fullness in sequence. Therefore, the anhidrosis is due to Fullness-symptoms. (9) The causes of forehead sweat are due to Heat-fullness, Moisture-evil, and Yang-weakness in sequence. (10) The origins of extreme ties sweat are due to spleen-stomach-fullness, Heatfullness and Coldness-evil in sequence. The Fullness-heat of spleen-stomach is most important cause of palmar sweat. (11) The causes of sternum sweat are due to excessive thinking and amazement in sequence. The fore 7 excessive emotions are important causes by sternum sweat. (12) The feverish sweat due to Dryness-evil Moisture-evil, Heat-evil and Wind-evil may well be included in endemic diseses.

漢方治療用 藥材의 地域特産性 調査硏究 : 生産 및 消費構造를 中心으로

辛民敎,柳聖圭,柳熙英 圓光大學校 1980 論文集 Vol.14 No.2

According to my research on the subject the followings are the conclusions: (Ⅰ)We should study regional characteristics of productions. (Ⅱ)We need the investigation and analysis of the soil and herb's qualities. (Ⅲ)And also we should study the comparative research on the subject of fertilization and herb's qualities. (Ⅳ)The fact that time of partial harvest of each herbs is how effective on qualities should be investigated. (Ⅴ)The improvements of herb's storage and market system form should be considered seriously. (Ⅵ)For the purposes of the analysis of essential efficacies and economic circumstances about oriental medical herbs, I would like summarize as follows as my conclusions. 1. I proposed, already, introduced synthetically established larger planting areas according to the studies of environmental biology and its medical plnats and economics, constituting 91 kinds including Ostericum Koreana. 2. According to the conclusion that 87 kinds of Korean products and 157 foreign products under comparative researches, I found out that producing of other many medical herbs could be productive in Korean wasted lands considering those herbs can grow even on the sandy lands in foreign countries which are successful in prod-ucing fruitful plants. 3. It is well-known fact that the efficacies of every medical herbs are depend upon temperature, water permeabilty, basic fertilization and after-fertilization. Skin groups should be collected at June or July, medical groups full-bloom or little bit later, flower groups full-bloom or after that, all herbal medicine full-bloom time, the roots in March or September, the fruits or seeds in September or October. 4. All medical herb products should be controlled under the sponsor of Monopoly Bureau just as ginseng. 5. According to the reports of WHO it is learned that oriental medicines have impricated and natural meanings, and after the early 1970 the exports of Korean medical herbs to foreign countries showed very encouraging. 6. At any rate, above mentioned facts must be handled at the government(ROK) level.