Inter- and Intra-Observer Variability of the Volume of Cervical Ossification of the Posterior Longitudinal Ligament Using Medical Image Processing Software

Shin, Dong Ah,Ji, Gyu Yeul,Oh, Chang Hyun,Kim, Keung Nyun,Yoon, Do Heum,Shin, Hyunchul The Korean Neurosurgical Society 2017 Journal of Korean neurosurgical society Vol.60 No.4

Objective : Computed tomography (CT)-based method of three dimensional (3D) analysis ($MIMICS^{(R)}$, Materialise, Leuven, Belgium) is reported as very useful software for evaluation of OPLL, but its reliability and reproducibility are obscure. This study was conducted to evaluate the accuracy of $MIMICS^{(R)}$ system, and inter- and intra-observer reliability in the measurement of OPLL. Methods : Three neurosurgeons independently analyzed the randomly selected 10 OPLL cases with medical image processing software ($MIMICS^{(R)}$) which create 3D model with Digital Imaging and Communication in Medicine (DICOM) data from CT images after brief explanation was given to examiners before the image construction steps. To assess the reliability of inter- and intra-examiner intraclass correlation coefficient (ICC), 3 examiners measured 4 parameters (volume, length, width, and length) in 10 cases 2 times with 1-week interval. Results : The inter-examiner ICCs among 3 examiners were 0.996 (95% confidence interval [CI], 0.987-0.999) for volume measurement, 0.973 (95% CI, 0.907-0.978) for thickness, 0.969 (95% CI, 0.895-0.993) for width, and 0.995 (95% CI, 0.983-0.999) for length. The intra-examiner ICCs were 0.994 (range, 0.991-0.996) for volume, 0.996 (range, 0.944-0.998) for length, 0.930 (range, 0.873-0.947) for width, and 0.987 (range, 0.985-0.995) for length. Conclusion : The medical image processing software ($MIMICS^{(R)}$) provided detailed quantification OPLL volume with minimal error of inter- and intra-observer reliability in the measurement of OPLL.

HFC 망에서 대용량 방송서비스를 위한 채널 결합 기반 전송 방식 및 시뮬레이터 개발

신현철(Hyunchul Shin),이동열(Dongyul Lee),유웅식(Woongshik You),최동준(Dongjoon Choi),이채우(Chaewoo Lee) 한국방송·미디어공학회 2011 방송공학회논문지 Vol.16 No.5

The Behavioral Effects of Combination Therapy of Memantine and Acetylcholinesterase Inhibitors Compared with Acetylcholinesterase Inhibitors Alone in Patients with Moderate Alzheimer’s Dementia: A Double-Blind Randomized Placebo-Controlled Trial

Youn HyunChul,Lee Kang Joon,Kim Shin-Gyeom,Cho Seong-Jin,Kim Woo Jung,Lee Won Joon,Hwang Jae Yeon,Han Changsu,Shin Cheolmin,Jung Han-yong 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.3

Objective This study aimed to investigate treatment effects of combination therapy of memantine and acetylcholinesterase inhibitors (AchEIs) compared with AchEIs alone on behavioral and psychological symptoms of dementia (BPSD) in patients with moderate Alzheimer’s dementia (AD).Methods This was a 12-week, double-blind, randomized, placebo-controlled trial. A total of 148 patients with moderate AD participated in this study. Mini-Mental State Examination, Neuropsychiatric Inventory (NPI), Clinician’s Interview-Based Impression of Change plus caregiver input, Gottfries–Bråne–Steen Scale, and Zarit Burden Interview were used as assessment scales.Results There were no significant differences in age, sex, or education between AChEIs alone and combination groups. The combination group showed significantly more improvement of NPI-disinhibition score (0.76±2.15) than the AChEIs alone group (-0.14±1.71) after 12 weeks.Conclusion Our findings suggest that the combination therapy of memantine and AchEIs might be a beneficial option for reducing disinhibition symptoms of patients with moderate AD compared with AchEIs alone. We believe that clinicians need to consider additional memantine treatment when patients with moderate AD complain disinhibition symptom. A larger clinical trial is needed to further determine the efficacy and advantages of such combination therapy of memantine and AchEIs for treating BPSD of patients with moderate AD.

PRP for Arthroscopic Repair of Medium to Large Rotator Cuff Tears: Response

Jo, Chris Hyunchul,Shin, Ji Sun,Shin, Won Hyoung,Lee, Seung Yeon,Yoon, Kang Sup,Shin, Sue SAGE Publications 2016 AMERICAN JOURNAL OF SPORTS MEDICINE - Vol.44 No.2

Platelet-Rich Plasma for Arthroscopic Repair of Medium to Large Rotator Cuff Tears : A Randomized Controlled Trial

Jo, Chris Hyunchul,Shin, Ji Sun,Shin, Won Hyoung,Lee, Seung Yeon,Yoon, Kang Sup,Shin, Sue SAGE Publications 2015 AMERICAN JOURNAL OF SPORTS MEDICINE - Vol.43 No.9

<P><B>Background:</B></P><P>Two main questions about the use of platelet-rich plasma (PRP) for regeneration purposes are its effect on the speed of healing and the quality of healing. Despite recent numerous studies, evidence is still lacking in this area, especially in a representative patient population with medium to large rotator cuff tears.</P><P><B>Purpose:</B></P><P>To assess the efficacy of PRP augmentation on the speed and quality of healing in patients undergoing arthroscopic repair for medium to large rotator cuff tears.</P><P><B>Study Design:</B></P><P>Randomized controlled trial; Level of evidence, 1.</P><P><B>Methods:</B></P><P>A total of 74 patients scheduled for arthroscopic repair of medium to large rotator cuff tears were randomly assigned to undergo either PRP-augmented repair (PRP group) or conventional repair (conventional group). In the PRP group, 3 PRP gels (3 × 3 mL) were applied to each patient between the torn end and the greater tuberosity. The primary outcome was the Constant score at 3 months after surgery. Secondary outcome measures included the visual analog scale (VAS) for pain, range of motion (ROM), muscle strength, overall satisfaction and function, functional scores, retear rate, and change in the cross-sectional area (CSA) of the supraspinatus muscle.</P><P><B>Results:</B></P><P>There was no difference between the 2 groups in the Constant score at 3 months (<I>P</I> > .05). The 2 groups had similar results on the VAS for pain, ROM, muscle strength, overall satisfaction and function, and other functional scores (all <I>P</I> > .05) except for the VAS for worst pain (<I>P</I> = .043). The retear rate of the PRP group (3.0%) was significantly lower than that of the conventional group (20.0%) (<I>P</I> = .032). The change in 1-year postoperative and immediately postoperative CSAs was significantly different between the 2 groups: –36.76 ± 45.31 mm<SUP>2</SUP> in the PRP group versus −67.47 ± 47.26 mm<SUP>2</SUP> in the conventional group (<I>P</I> = .014).</P><P><B>Conclusion:</B></P><P>Compared with repairs without PRP augmentation, the current PRP preparation and application methods for medium to large rotator cuff repairs significantly improved the quality, as evidenced by a decreased retear rate and increased CSA of the supraspinatus, but not the speed of healing. However, further studies may be needed to investigate the effects of PRP on the speed of healing without risking the quality.</P>

A Single Camera Tracking System for 3D Position, Grasper Angle, and Rolling Angle of Laparoscopic Instruments

Shin, Sangkyun,Kim, Youngjun,Cho, Hyunchul,Lee, Deukhee,Park, Sehyung,Kim, Gerard Jounghyun,Kim, Laehyun Korean Society for Precision Engineering 2014 International Journal of Precision Engineering and Vol.15 No.10

Advances in computer vision technology and virtual reality technology have been achieved through improvements in camera performance and computability. Cost-effective simulation systems for laparoscopic surgery are proposed by combining such technologies. In this study, we propose a novel 3D instrument tracking technique using a single camera to obtain the 3D positions, roll angle, and grasper angle of a laparoscopic instrument. The 3D tracking of the instrument requires that all of the markers are collinear and that the actual distances between markers are known The results of our study show that the minimum uncertainty in the position was 0.237 mm and the maximum uncertainty in the position was 1.476 mm.

Neuropsychological Tests for Patients with Marchiafava-Bignami Disease: A Case Report

HyunChul Youn,Soyoung Irene Lee,Shin-Gyeom Kim,Jeewon Lee,Han-yong Jung 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.12

반도체 IP 개발 및 활용에 관한 연구

신현철 漢陽大學校 工學技術硏究所 1999 工學技術論文集 Vol.8 No.1

본 논문에서는 집적회로 설계에 있어서 지적 재산권 (Intellectual Property, IP)을 재사용하는 최근의 경향과 설계 기술을 설명한다 IP 재사용을 활성화시키기 위하여 VSIA, RAPID 및 VCX와 같은 여러 기관들이 설립되었으며, IP 산업을 위하여 CAD 업체들이 재구성되고 있다. IP는 소프트 IP, 펌 IP 및 하드 IP의 세 가지로 구분될 수 있다. 본 논문에서는 IP를 위한 설계 과정과 설계 기법들을 조사하였다. 효과적이고 효율적인 IP 재사용을 위해서는 설계 초기에서부터 DSM 영향을 고려할 수 있는 상위 수준의 floorplanning 틀을 개발하여야 한다. This paper describes recent trends and design technologies for Intellectual Property reuse in integrated circuit design. Several organizations, such as VSIA, RAPID and VCX, have been established to activate IP reuse, and CAD industries have been reorganized for IP business. IPs can be classified into 3 types: Soft IP, Firm IP, and Hard IP Design process for IPs and design technologies for IP reuse are studied. For efficient and effective IP reuse, high-level floorplanning tools which can consider DSM effects from the beginning of the design should be developed.

Mesoporous Carbon Nanorod from Direct Templating Method and Its Application to Electric Double-layer Capacitor (EDLC) Electrodes

Hyunchul Kang(강현철),Kibum Hwang(황기범),Eunseon Shin(신은선),Jaekwang Kim(김재광),Sung Gyu Pyo(표성규),Songhun Yoon(윤성훈) 한국고분자학회 2021 폴리머 Vol.45 No.3

양이온계 계면활성제와 실리케이트 용액의 자기조립 반응을 이용하여 기공 형성의 주형으로 이용하고 여기에 레소시놀-포름알데하이드를 투여한 후 고분자화 반응을 통하여 계면활성제/실리케이트/고분자 나노 복합체를 제조하였다. 제조된 나노 복합체를 고온에서 탄화하고 이를 불산으로 에칭하여 메조다공성 나노막대형 탄소 재료를 성공적으로 제조하였다. 제조된 메조다공성 나노 막대 탄소 재료를 전기이중층 캐패시터 전극으로 적용하였으며, 다양한 전기화학 실험을 통하여 그 성능을 평가하였다. 이 결과 잘 발달된 메조 기공 내부의 원활한 이온 전달 특성 및 나노 막대에서의 최적화된 기공 길이로 인해, 기존의 활성탄 재료보다 매우 우수한 속도 특성(낮은 기공 저항) 및 높은 면적당 캐패시턴스(17.4 μF cm<SUP>-2</SUP>)를 갖는 전기이충층 캐패시터 전극 재료를 제조할 수 있었다. Using the self-assembly reaction between cationic surfactant and silicate solution, a direct templating method was investigated. After the addition of resorcinol and formaldehyde into the solution, the polymerization reaction was conducted and surfactant/silicate/polymer nanocomposite was prepared. After carbonization and following hydrofluoric acid etching, mesoporous carbon nanorod (MPCNR) particles were prepared. As-prepared material was applied into electrode in electric double-layer capacitors and various electrochemical analysis was carried out using the electrodes. Due to the well-developed mesoporosity and nanosized rod particles, a highly improved rate performance (low resistance in pores) and large double layer capacitance per area (17.4 μF cm<SUP>-2</SUP>) than the commercialized activated carbon electrode were observed, which was attributed to easy penetration through mesopores and optimized pore length for electrolyte transport.

Anterior Cable Reconstruction using the Biceps Tendon in Retracted Anterior L-shaped Rotator Cuff Tears

Hyunchul Yang,Inwoo Kim,Min-su Kim,Sanghyeon Lee,Sang-Jin Shin 대한견주관절의학회 2021 대한견주관절학회 학술대회논문집 Vol.2021 No.3

Introduction and Background The characteristic of anterior L-shaped rotator cuff tear is a retracted supraspinatus to the glenoid level combined with a relatively preserved infraspinatus tendon. A degenerated anterior margin of the supraspinatus tendon and frayed tissue involving the rotator interval induce lack of mobilization and hinder stable anatomic reduction without tension. The purpose of this study was to evaluate clinical outcomes and tendon integrity in patients those who underwent anterior cable reconstruction using the biceps tendon in retracted anterior L-shaped rotator cuff tears. Material and Method A total of 43 consecutive patients with symptomatic full-thickness rotator cuff tears with anterior L-shaped tear who underwent arthroscopic rotator cuff repair between May 2018 and August 2020 were retrospectively reviewed Patients with severe biceps tendon tear those who cannot underwent anterior cable reconstruction were excluded from this study. Patients who were not followed up for more than 6 months postoperatively were also excluded. Results Consequently, a total of 37 patients were analyzed in this study. The mean sizes of the preoperative anterior L-shaped tear were 22.9±5.7 mm in the anterior-to-posterior direction and 30.1±5.0 mm in the medial-to-lateral direction. Postoperative functional outcomes improved significantly in terms of mean VAS, ASES, Constant scores and SANE score compared with preoperative values and improved significantly after repair. Complete structural integrity of the repaired tendon was observed on postoperative MRI in 23 patients. At final follow-up, popeye sign was observed in 4 patients. No major complications such as infection or neurovascular injury were observed. Conclusions The tenodesed proximal biceps tendon can act as the anterior part of the rotator cable and reinforce rotator cuff repair by suturing the torn cuff together. Anterior cable reconstruction using the biceps tendon is considered as one of the surgical options for patients with retracted anterior L-shaped rotator cuff tears.