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      • 詩經正變設考

        金時俊 서울대학교 동아문화연구소 1979 東亞文化 Vol.16 No.-

        It was written at the Mao Shi prefaces (毛詩序) that Shi Jing was divided into two groups; the Zheng Poem and the Bian Poem. According to this, many scholars published various assertions on how to distinguish the Zheng Poem from the Bian Poem in Shi Jing. Conseguently, these assertions were classified into four sorts. 1) Classification by the chronological order according to the political rise and fall 2) Distinction between eulogy and satire 3) Distinction the Poem which was accompanied by music from the poem which was not accompanied by it, 4) Classification by the style of the poem My study on each assertion leads to the following conclusion: 1) Although those scholars who made the first assertion defined that Shi Jing was published by the chronological order and they distinguished the Zheng Poem from the Bian poem by the table of contents, it is proved that Shi Jing was not published by the chronological order. 2) Those scholars who made the second assertion concluded that Shi-Jing was distinguished between eulogy and satiry at every prologue in Mao Shi and that the Zheng poem and the Bian Poem could be divided into eulogy or satire accordingly. But it is proved herein that the distinction eulogy from satire in Mao Shi prefaces was possible by the country and chronology without the definite standard even though the contents of the poem were the same. 3) Those scholars who made the third assertion divided Shi Jing into two parts. One that was accompanied by music was called the Zheng Poem and the other that was accompanied by music was called the Bian Poem. But it is proved that all of Shi Jing were accompanied by music 4) Those who made the fourth assertion distinguished between the Zheng Poem and the Bian Poem by the style of the Poem. But looking into the style, it is proved that the distinction between the Zheng Poem and the Bian Poem is the style itself. Thus, the above classifications seem to be unreasonable so far. Then, why did these assertions come to rise? These assertions were due to the Han scholars who regarded the poem as a remonstration. They attempted to classify the Zheng Poem as the poem of admonition and the Bian poem as that of warning. But they did not succeed in it.

      • Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps Sinensis in the Bronchoalveolar Lavage Fluids Cells

        Kuo, Yuh-Chi,Wu, Chia-Lin,Tasi, Wei-Jern,Wang, Jir-Yenn,Chang, Shi-Chung,Lin, Ching-Yuang,Shiao, Ming-Shi 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang₃,Ching-Yung Lin⁴,and Ming-Shi Shiao⁴¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang²,Ching-Yung Lin³,and Ming-Shi Shiao⁴.¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan. Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps sinensis in the Bronchoalveolar Lavage Fluids Cells. Proceedings of international Symposium on East-West Medicine, Seoul. 44-64, 1999.-Cordyceps sinensis is a major parasitic fungus on larva of Lepidoptera. It is one of the well know fungi used in traditional Chinese medicine for treatment asthma, lung and kideney diseases. Many fungi belonging to the genus Cordyceps have been demonstrated to produce natural products with various biological activities. Reported biological activities of genus cordyceps include:(a)inhibition of DNA and RNA synthesis;(b)enhancement of cell differentiation;(c)restruction of cytoskeleton;(d)inhibition of protein kinase activity;(e)antitumor activity on bladder, colon, lung carcinoma as well as fibroblastoma;(f)inhibition of the infection and revers transciptase activity of human immunodeficiency virus type 1; and(g) inhibition of methylation of nucleic acid. Thus, it is suggested that the extracts of Cordyceps sp. Contain antitumor, antiviral, and many other biological activities. In our previous studies, we proved that C. sinensis contains the antitumor and immunomodulatory agents. In the present studies, effects of C. sinensis on bronchoalveolar lavage fluids(BAL)cells were demonstrated. The crude methanolic extracts of C. sinensis were fractionated into 15 fractions by silica gel column chromatography. Effects of various fraction on BAL cells proliferation and lipopolysaccharide(LPS) stimulated interleukin-1β(IL-8),platelet activating factor(PAF), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α),and interleukin-8(IL-8) production on BAL cells were determined. The result indicated that the CS-19-22 fraction suppressed BAL cells proliferation activated by LPS. The median inhibitory concentration(IC50) was 6㎍/ml. The CS-19-22 fraction also decreased IL-1β,PAF,IL-6, TNF-αand IL-8 production.The results of revers transcription-polymerase chain reaction(RT-PCR) demonstrated that the CS-19-22 fraction did not affect IL-1β,PAF,IL-6, TNF-α,and IL-8 mRNAs expression in BAL cells activated by LPS. By contrast, it inhibited the IL-10 mRNA expression but enhanced IFN-γand IL-12 mRNAs expression in activated BAL cells. Moreover, the CS-19-22 fraction blocked PAF-induced platelet aggregation. It is unlikely that cytotoxicity was involved. Because no cell deths were observable. We hypothesize that inhibitory mechanisms of CS-19-22 on BAL cells proliferation may be related to the impairments of gene expression and production of cytokines in BAL cells. The explanation of C. sinensis antiasthma function may involved the following(1)C.sinenesis contained immunomodulatory agents that stimulated IFN-γand IL-12 expression in TH1cells.(2)Enhanced secretion of IFN-γand IL-12 will inhibit the Tγcells immune responses Ex. Decreasing of IL-6 and IL-10 production.(3) The impairments of cytokines production in TH2 cells suppressed th BAL cells proliferation then more cytokines production Ex.IL-1β,PAF,IL-6,TNF-αand IL-8 in activated BAL cells were decreased. (4)The suppression of TH2cells immune responses will inhibit the growth and differentiation of B cells then IgE production will be decreased. (5)Reduced production of IgE will decreased asthma attack occurring in individuals. However, the results of the present study suggested that C. sinensis may also have acted to treat asthma in part by inhibiting BAL cells proliferation and cytokine gene expression and production. Future, experiments with treatment of animals with asthma with C. sinensis will be necessary to defined whether C. sinensis can reduce asthma injury. Plans are underway for the isolation of pure principal growth inhibitors and their mechanisms of action are subjected for further study.

      • KCI등재

        Hot Deformation Characteristics and Processing Map Analysis of Pre-Forged AZ80 Magnesium Alloy

        Shi‑quan Huang,Ming Lu,Sheng‑lan Luo,Hai‑lin He,You‑ping Yi 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5

        The hot deformation behavior of pre-forged AZ80 magnesium alloy is investigated by the isothermal compression tests attemperatures of 523–683 K and strain rates of 0.0001–0.1 s−1, and analyzed by the processing maps for guiding isothermaldie forging. Flow localization and even cracking occurs at low temperatures and high strain rates, where shear deformationdegree shows a positive correlation with the ��( ̇�� ) value. Two stability regions with high efficiency is found out by theprocessing maps. At common stability region with high temperatures and low strain rates, peak power dissipation efficiencydoes not represent optimum deformation condition as reported in other materials. A Z parameter criterion is introduced forparameters optimization. javascript:void(0); a new stability domain of 523–590 K and 0.0001–0.01 s−1 is observed, which istypical for fine microstructure composed of equiaxed clean α-Mg grains and big particles both about 1 μm (573 K/0.01 s−1).Super plasticity is speculated to occur at that condition.

      • KCI등재후보
      • SCOPUSKCI등재
      • 最大乾燥密度와 最適含水比에 對하여 : 남부지방을 중심으로 At the southern District

        柳時昶,李裕根 진주산업대학교 1972 論文集 Vol.10 No.-

        It is one of the most economical method of Soil stabilization works to compact soil, which increases soil density artificially. The result obtained in this study on the effect that optimum moisture content and plastic Linit, natural moisture content, influence upon the maximum dry density effort 36 Samples are Summarized as follows. 1. The bigger the maximum dry density is, the smaller the optimum moisture content is, on the other hand, the smaller the maximum dry density is, the bigger the optimum moisture content is, ingeneral. 2. There is a relation which is rdmax=1/[0.00895(OMC+44.73)] between the maximum dry density and the optimum moisture content, namely, the maximum dry density is increased in propertion to decrease of the optimum moisture content. 3. There is a relation which is OMC=0.438+0.395 PL and OMC=42.30-1.20Wn 4. There are relation to be the straightline which the maximum dry density decrease, on the other hand, The optimum moisture content increase in accordance with enlargement of Atter berg Limit (LL.PL.PI) in compacted soils.

      • 소아 중증 두뇌손상환자에 대한 임상적 고찰

        송시헌 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

        The purpose of this study is to report the outcomes of 73 children, 15 years of age or younger, who were consecutively admitted to Chungnam National University Hospital over a 5-year period with nonpenetrating severe brain injury and to compare these results with reports from other centers in a community with well trained paramedic care and an excellent transfer system. In addition, clinical analysis of the relationship between age, initial GCS score, coma duration, clinical findings, intracranial lesions and outcome have been studied. The results were as follows : 1. The average age was 8.7 years and occured predominantly in males(2.3 : 1 ratio). 2. The most common cause of brain injury was motor vehicle accident (84.9%). 3. The number of patients with intracranial hematoma was 25(34.2%) and patients with acute subdural hematoma showed the poorest outcome. 4. Seventeen patients(23.3%) died, fourty-six patients(63%) recovered functionally and ten patients (13.7%) showed a nonfunctional outcome. 5. A significant relationship was found between outcome, initial GCS score and bilateral pupillary abnormalities. However, the age, duration of coma, other clinical findings and intracranial lesions, except acute subdural hematoma, did not relate to the outcome.

      • 韓國에 있어서의 最大降雨量에 對한 硏究

        柳時昶 진주산업대학교 1970 論文集 Vol.4 No.-

        The purpose of this research is to obtain the design basins for various hydrologic construction with the specific system which suits the natural environmental condition in Korea. Ⅰ) Maximum rainfall per minute is correlated in certain degree with the daily rainfall, and following formular is obtained empirically. Y=19.1 T^0.45 T≤73.5hr Y=108.5 T^0.45 T≥73.5hr Ⅱ) The influence of the missed number of observed years is such that 60 years at the Maximum are allowable with a certain risk, and one year is negligible.

      • 우리나라의 耕地汎用化 事業動向과 그 問題點의 解決方案 模索

        金始源,呂運植,金瀅中,金善柱 建國大學校 附設 農業資源開發硏究所 1993 農資源開發論集 Vol.18 No.-

        To make a smooth progress in the multi-utilization undertaking of paddy land, land consolidation is the most important task among the various countermeasures. This study discusses the types and efficiency of subsurface drainage systems, and suggestes their maintenance and management schemes. The results are summarized as follows: 1) Recently an introduction of subsurface drainage systems has been employed. Especially the necessity of subsurface drainage systems has been widely recognized at farms in the suburban districts, however, the undertaking itself cannot overcome an experimental stage. Therefore, studies on the selection of project areas and operation systems should be executed together with the technical establishment. 2) To drive forward the land improvement project reasonably and efficiently, the realities of regional farmings and the natural conditions should be considered, so it is desirable to establish a longterm land improvement plan based on the nation-wide angle of view. 3) To create the multi-utilization paddy land from the single cropping paddy land, the following items should be consolidated. First, reorganize the utilization pattern of paddy land possible to adopt multi-utilization system. Second, land should be consolidated as a large size possible to operate big agricultural machines. Third, develop fundamental techniques for the multi-utilization system. Fourth, collectivization of agricultural land. Fifth, environmental consolidation of the rural community. 4) The maintenance and management technique of the subsurface drainage system should be studied. Since the function of system could be lost by the clog up of drainage pipe, the efficiency and function of system should be recognized for the smooth maintenance and management.

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