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      • 詩經正變設考

        金時俊 서울대학교 동아문화연구소 1979 東亞文化 Vol.16 No.-

        It was written at the Mao Shi prefaces (毛詩序) that Shi Jing was divided into two groups; the Zheng Poem and the Bian Poem. According to this, many scholars published various assertions on how to distinguish the Zheng Poem from the Bian Poem in Shi Jing. Conseguently, these assertions were classified into four sorts. 1) Classification by the chronological order according to the political rise and fall 2) Distinction between eulogy and satire 3) Distinction the Poem which was accompanied by music from the poem which was not accompanied by it, 4) Classification by the style of the poem My study on each assertion leads to the following conclusion: 1) Although those scholars who made the first assertion defined that Shi Jing was published by the chronological order and they distinguished the Zheng Poem from the Bian poem by the table of contents, it is proved that Shi Jing was not published by the chronological order. 2) Those scholars who made the second assertion concluded that Shi-Jing was distinguished between eulogy and satiry at every prologue in Mao Shi and that the Zheng poem and the Bian Poem could be divided into eulogy or satire accordingly. But it is proved herein that the distinction eulogy from satire in Mao Shi prefaces was possible by the country and chronology without the definite standard even though the contents of the poem were the same. 3) Those scholars who made the third assertion divided Shi Jing into two parts. One that was accompanied by music was called the Zheng Poem and the other that was accompanied by music was called the Bian Poem. But it is proved that all of Shi Jing were accompanied by music 4) Those who made the fourth assertion distinguished between the Zheng Poem and the Bian Poem by the style of the Poem. But looking into the style, it is proved that the distinction between the Zheng Poem and the Bian Poem is the style itself. Thus, the above classifications seem to be unreasonable so far. Then, why did these assertions come to rise? These assertions were due to the Han scholars who regarded the poem as a remonstration. They attempted to classify the Zheng Poem as the poem of admonition and the Bian poem as that of warning. But they did not succeed in it.

      • Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps Sinensis in the Bronchoalveolar Lavage Fluids Cells

        Kuo, Yuh-Chi,Wu, Chia-Lin,Tasi, Wei-Jern,Wang, Jir-Yenn,Chang, Shi-Chung,Lin, Ching-Yuang,Shiao, Ming-Shi 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang₃,Ching-Yung Lin⁴,and Ming-Shi Shiao⁴¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang²,Ching-Yung Lin³,and Ming-Shi Shiao⁴.¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan. Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps sinensis in the Bronchoalveolar Lavage Fluids Cells. Proceedings of international Symposium on East-West Medicine, Seoul. 44-64, 1999.-Cordyceps sinensis is a major parasitic fungus on larva of Lepidoptera. It is one of the well know fungi used in traditional Chinese medicine for treatment asthma, lung and kideney diseases. Many fungi belonging to the genus Cordyceps have been demonstrated to produce natural products with various biological activities. Reported biological activities of genus cordyceps include:(a)inhibition of DNA and RNA synthesis;(b)enhancement of cell differentiation;(c)restruction of cytoskeleton;(d)inhibition of protein kinase activity;(e)antitumor activity on bladder, colon, lung carcinoma as well as fibroblastoma;(f)inhibition of the infection and revers transciptase activity of human immunodeficiency virus type 1; and(g) inhibition of methylation of nucleic acid. Thus, it is suggested that the extracts of Cordyceps sp. Contain antitumor, antiviral, and many other biological activities. In our previous studies, we proved that C. sinensis contains the antitumor and immunomodulatory agents. In the present studies, effects of C. sinensis on bronchoalveolar lavage fluids(BAL)cells were demonstrated. The crude methanolic extracts of C. sinensis were fractionated into 15 fractions by silica gel column chromatography. Effects of various fraction on BAL cells proliferation and lipopolysaccharide(LPS) stimulated interleukin-1β(IL-8),platelet activating factor(PAF), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α),and interleukin-8(IL-8) production on BAL cells were determined. The result indicated that the CS-19-22 fraction suppressed BAL cells proliferation activated by LPS. The median inhibitory concentration(IC50) was 6㎍/ml. The CS-19-22 fraction also decreased IL-1β,PAF,IL-6, TNF-αand IL-8 production.The results of revers transcription-polymerase chain reaction(RT-PCR) demonstrated that the CS-19-22 fraction did not affect IL-1β,PAF,IL-6, TNF-α,and IL-8 mRNAs expression in BAL cells activated by LPS. By contrast, it inhibited the IL-10 mRNA expression but enhanced IFN-γand IL-12 mRNAs expression in activated BAL cells. Moreover, the CS-19-22 fraction blocked PAF-induced platelet aggregation. It is unlikely that cytotoxicity was involved. Because no cell deths were observable. We hypothesize that inhibitory mechanisms of CS-19-22 on BAL cells proliferation may be related to the impairments of gene expression and production of cytokines in BAL cells. The explanation of C. sinensis antiasthma function may involved the following(1)C.sinenesis contained immunomodulatory agents that stimulated IFN-γand IL-12 expression in TH1cells.(2)Enhanced secretion of IFN-γand IL-12 will inhibit the Tγcells immune responses Ex. Decreasing of IL-6 and IL-10 production.(3) The impairments of cytokines production in TH2 cells suppressed th BAL cells proliferation then more cytokines production Ex.IL-1β,PAF,IL-6,TNF-αand IL-8 in activated BAL cells were decreased. (4)The suppression of TH2cells immune responses will inhibit the growth and differentiation of B cells then IgE production will be decreased. (5)Reduced production of IgE will decreased asthma attack occurring in individuals. However, the results of the present study suggested that C. sinensis may also have acted to treat asthma in part by inhibiting BAL cells proliferation and cytokine gene expression and production. Future, experiments with treatment of animals with asthma with C. sinensis will be necessary to defined whether C. sinensis can reduce asthma injury. Plans are underway for the isolation of pure principal growth inhibitors and their mechanisms of action are subjected for further study.

      • KCI등재후보
      • KCI등재

        Hot Deformation Characteristics and Processing Map Analysis of Pre-Forged AZ80 Magnesium Alloy

        Shi‑quan Huang,Ming Lu,Sheng‑lan Luo,Hai‑lin He,You‑ping Yi 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5

        The hot deformation behavior of pre-forged AZ80 magnesium alloy is investigated by the isothermal compression tests attemperatures of 523–683 K and strain rates of 0.0001–0.1 s−1, and analyzed by the processing maps for guiding isothermaldie forging. Flow localization and even cracking occurs at low temperatures and high strain rates, where shear deformationdegree shows a positive correlation with the ��( ̇�� ) value. Two stability regions with high efficiency is found out by theprocessing maps. At common stability region with high temperatures and low strain rates, peak power dissipation efficiencydoes not represent optimum deformation condition as reported in other materials. A Z parameter criterion is introduced forparameters optimization. javascript:void(0); a new stability domain of 523–590 K and 0.0001–0.01 s−1 is observed, which istypical for fine microstructure composed of equiaxed clean α-Mg grains and big particles both about 1 μm (573 K/0.01 s−1).Super plasticity is speculated to occur at that condition.

      • SCOPUSKCI등재
      • 강직성 뇌성마비 환아를 위한 선택적 척수 후신경근 절단술

        송시헌 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2

        Cerebral palsy is a multifaceted disorder of which spasticity is only one aspect. Selective posterior rhizotomy(SPR) is a well-established treatment for spasticity associated with cerebral palsy and favorable results have been reported from a number of different centers. However, the techniques used in performing SPR to treat spastic cerebral palsy remains controversial. A review of the personal experience of the SPR performed at Chungnam National University Hospital(CNUH) for reduction of spasticity in children with cerebral palsy is presented. The SPR procedure performing in CNUH involves an L1 and L2 laminectomy, followed by the about 60.9% selective section of certain lumbosacral posterior spinal nerve rootlets(Ll-S1 or S2), based on the electromyographic responses to their electrical stimulation. All patients showed markedly relieved or disappeared spasticity on post-rhizotomy neurologic examination. Postoperative physical and occupational therapy are felt to be essential for regaining strength and improving motor function following the SPR.

      • 정치경제학 이론의 적용

        이시영,이효찬 중앙대학교 산업경영연구소 1999 산업경영연구 Vol.8 No.1

        본 연구의 목적은 최근에 관심을 끌고 있는 정치경제학적 이론을 간략히 소개하고 실질적인 졍재정책의 적용사례를 제시하는데 있다. 기존 전통경제학에서 정부의 역할은 지극히 제한되어 정부의 개입은 시장의 실패가 발생하였을 때만 정당화되었다. 반면 정치경제학적 접근은 기본적으로 경제정책의 결정은 정치집단의 상호작용의 결과로 가정하고 있다. 그리고 정치적 이해의 상호작용에 의하여결정된 경제정책은 (경제학적 관점에서 보면) 비효율적일 수 있다는 점을 강조하고 있다. 실질적인 사례를 통하여 정부 경제정책의 형성과정을 설명하고 그러한 정책들이 정치적 거래비용을 최소화하는 정책임을 보여주는데 본 논문의 의의가 있다고 할 수 있다. This paper introduces the recent developments of political economic approach and provides some applications. The traditional economic approach has failed to successfully explain the emergence of the existing economic policies. On the other hand, the political economy approach that we adopt here provides some realistic insights to the making of economic policy. The first application deals with the amendments of the U.S. anti-dumping laws. We claim that the main motivation behind these amendments aimed to delay the exits of (politically important) declining industries. The second application concerns with ″big deal″ (swap of subsidiaries among Chaebols) scheme. The existing Korean government selected this particular scheme to minimize its political costs (rather than enhance economic efficiency). The antagonistic mood toward foreign ownerships of domestic firms coupled with the high unemployment were responsible for this selection. The third application explains ″the wind from the North″. It explicitly provides the motive of the incumbent government to form the coalition with a ″potential″ enemy. When the incumbent government suffers from the credibility problem, the coalition with the enemy may temporarily create ″potential threat″ to its own citizens and help to win the re-election bid. The fourth application explains how implicit government guarantees had been concerns with conflicts of interests between the federal and local governments and may generate economically inefficient delay of investment in social infrastructures.

      • 절벽의 보호재로 사용하는 철근의 부식에 따른 안정성 평가

        차시환 ; 권창오 김천대학교 1994 김천대학교 논문집 Vol.15 No.-

        The corrosion of metals is understood to be the degradation of the metallic structure at its surface through chemical reactions of the meal with species of the environment. From the standpoint of physical chemistry, corrosion processes belong to the general class of the phase boundary reactions. The subject of principal interest in this context is corrosion in the soil. Thus, the corrosion of steel by soil is the essential subject here. In many respects, similar basic principles apply for corrosion by pH, Temperature and rainfall : However, such special cases remain outside our consideration here. Evey study of corrosion processes has as its principal goal, if not to achieve apredictive calculation of the corrosion, at least to understand the data on the basic of a theory anal-ysis. if possible, then the corrosion rate much be quantitatively established as a function of the assential influencing parameters.

      • KCI등재후보

        해남유적지를 사례로 살펴본 문화ㆍ역사유적지를 테마로 하는 주제공원의 특징

        이시영,심준영 경희대학교 디자인연구원 2000 예술· 디자인학연구 Vol.3 No.1

        At the time of increasing of tourist demand, this study suggests the theme park which has the theme of historical and cultural relics, as the way that could solve the problems of historical and cultural tour and diverse tourist desire. Before that, this study examines the cases over domestic and overseas which have the theme of historical and cultural relics as the concept of the theme park. Than, as an internal case study, this study also presents the Proposal for the HaeNam Natural Historic Park which was planned at Haenam on 1998 by using dinosaur fossils as the main source of its concept. By doing so, this study aims at finding out the possibilities of The theme park which has the cultural tourist relics of Korea preserving the her own distinctive cultural heritage in the world.

      • 용해분산법에 의해 제조된 microcapsule의 방출 성능에 미치는 영향에 관한 연구

        차시환,김용욱 慶熙大學校 材料科學技術硏究所 1992 材料科學技術硏究論集 Vol.5 No.-

        Biodegradation of cruid oil at sea surface is limited with nutrients(N,P) concentration. Theoretically, cruid oil can be cleaned up by various skimming devices, but conditions seldem allow to succeed, our studies on the limiting factors of cruid oil biodegradation in natural seawater is responsetothe addition of nutrient(N,P). Nutrient, Consist of the ratio of 10 part ammonium chloride and 1 part of potassium phosphate, were encapsuled with waxes of n-paraffin and bees wax as the wall material. the improved way of preparation of microcapsules by hat methanol for high speed mixing with impeller could decrease the rate of nutrient release from the microcapsules and enhance the maximum amount of nutrient release. We confirm that enhancement of biodegradation by the addition of improved microcapsules. The materials used in the work as well as method of preparation of the spherical microcapsule(melting spray congealing method). For this purpose, the first objective is to obtain some sample(microcapsule) able to deliver the nutrient with a constant or a controlled rate. As a result, the release of nutrient salt in seawater shows interesting kinetics of release : the rate of nutrient salt delivery increases with a positive acceleration when an improved model of the microcapsule(I.M.C) is preparation.

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