Improved Stability Criteria for Discrete-time Delay Systems via Novel Summation Inequalities

Shen-Ping Xiao,Linxing Xu,Hong-Bing Zeng,Kok Lay Teo 제어·로봇·시스템학회 2018 International Journal of Control, Automation, and Vol.16 No.4

This paper is concerned with the stability analysis of linear discrete time-delay systems. New discrete inequalities for single summation and double summation are presented to estimate summation terms in the forward difference of Lyapunov-Krasovskii functional (LKF), which are more general than some commonly used summation inequalities. Through the construction of an augmented LKF, improved delay-dependent stability criteria for discrete time-delay systems are established. Based on this, a time-delayed controller is derived for linear discrete time-delay systems. Finally, the advantages of the proposed criteria are revealed from the solutions of the numerical examples.

Analysis on Robust Passivity of Uncertain Neural Networks with Time-Varying Delays via Free-Matrix-Based Integral Inequality

Shen-Ping Xiao,Hong-Hai Lian,Hong-Bing Zeng,Gang Chen,Wei-Hua Zheng 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.5

This paper investigates the robust delay-dependent passivity problem of neural networks (NNs) with time-varying delays and parameter uncertainties. A suitable augmented Lyapunov-Krasovskii functional (LKF) with triple integral term, which takes full use of the neuron activation function conditions and the information of time-delay in integral term, is constructed. Furthermore, by utilizing integral inequality proposed recently and the combining reciprocally convex method to estimate the derivative of the LKF, some less conservative robust passivity conditions are derived in terms of LMI. The superiority of presented approaches are demonstrated via two classic numerical examples.

대학생의 스마트폰 애플리케이션 이용동기와 이용행태

심효평(Xiao-Ping Shen),김도연(Doh-Yeon Kim) 부산울산경남언론학회 2013 지역과 커뮤니케이션 Vol.17 No.4

본 연구는 대학생 스마트폰 이용자들을 대상으로 스마트폰 애플리케이션의 이용동기를 조사하여 사회심리적 동기, 기능적 편의성 동기, 정보추구 동기, 오락 동기, 그리고 금융ㆍ쇼핑 동기 등 5개의 구체적 애플리케이션 이용동기를 발견하였다. 이 중 기능적 편의성 동기, 정보추구 동기, 오락 동기는 스마트폰 이용자들의 하루 이용시간과 무료 애플리케이션 설치 개수와 관련이 있었다. 스마트폰 이용자의 능동성은 스마트폰 애플리케이션 이용의 강력한 예측변인으로 나타나, 능동성이 높은 이용자일수록 더 일찍 스마트폰을 채택하여 더 오래 사용하며 더 자주 앱스토어를 방문하고 더 많은 애플리케이션을 설치하였다. 스마트폰을 더 일찍부터 채택한 사람일수록 더 많은 유료 애플리케이션을 설치한 것으로 나타났고, 이들은 경제활동 및 정보습득 관련 애플리케이션에 더 관심이 많았다. 아이폰 사용자들은 타 기종 사용자보다 더 많은 애플리케이션을 설치하고 자주 사용하는 애플리케이션도 더 많았다. Based on a survey of university students on their purposes for using smartphone apps, this study identifies five different motives: socio-psychological motive, functional convenience motive, information-seeking motive, entertainment motive, and banking/shopping motive. Among them, functional convenience, information-seeking, and entertainment motives are more closely connected with usage-hour and the number of apps loaded in their smartphones. Activeness of smartphone users is found to be a strong predictive variable for the usage of smartphones. Active users are likely to adopt the smartphone earlier, use smartphone more often, visit appstores more frequently, and load more apps onto their phones. On the other hand, early adopters have more paid apps on their smartphones, and are more interested in using the apps for economic activities and information-seeking purposes. Finally, iPhone users are more likely to load more appps and have more frequently-used apps than those of other brands.

Annual Financial Impact of Thyroidectomies for Nodular Thyroid Disease in China

Liu, Xiao-Yun,Zhu, Li-Jun,Cui, Dai,Wang, Zhi-Xiao,Chen, Huan-Huan,Duan, Yu,Shen, Mei-Ping,Zhang, Zhi-Hong,Wang, Xiao-Dong,Chen, Jia-Wei,Alexander, Erik Karl,Yang, Tao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14

A large proportion of patients with thyroid nodules in China undergo thyroidectomy in order to get confirmatory histology diagnosis. The financial impact of this modality remains to be investigated. To evaluate rationality of performing thyroidectomy without a routine FNA preoperatively from the economic perspective, we conducted a retrospective, observational study of all archival thyroidectomies with records of cost per stay (CPS), cost per day (CPD) and length of stay (LOS) from 2008 to 2013 in the First Affiliated Hospital of Nanjing Medical University. We compared all the parameters between cancer and non-cancer thyroidectomies. We recruited 6, 140 thyroidectomies with valid records of CPS, CPD and LOS in this period. The CPS of cancer thyroidectomy was significantly higher than non-cancer thyroidectomy. The percentage of cancer thyroidectomy increased from 26.5% to 41.6%. The percentage of annual cost of cancer thyroidectomies rose from 30.2% to 45.2%. The LOS for cancer and non-cancer thyroidectomy decreased while the CPD increased in the past six years. The estimated national cost in 2012 for all thyroidectomies would be USD 1.86 billion with USD 1.09 billion for non-cancer thyroidectomies. We have witnessed great improvement in the healthcare for patients with thyroid nodules in China. However, given limited healthcare resources, currently thyroid FNA for more precise preoperative diagnosis may help to curb the rapidly increasing demand in healthcare costs in the future for nodular thyroid disease in China.

A Topic Community Detection Method for Information Network based on Improved Label Propagation

SHEN Gui-Lan,YANG Xiao-Ping 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.2

A large number of emerging information networks brings new challenges to the community detection. The meaningful community should be topic-oriented. However, the topology-based methods only reflect the strength of connection, and ignore the consistency of the topics; the content-based methods focus on the contents and completely ignore the links. This paper explores a topic oriented community detection method simLPA based on label propagation for information work. The method utilizes Latent Dirichlet Allocation topic model to represent the node content, and calculate the content similarity by the normalized Kullback–Leibler divergence. simLPA extended by LabelRank fuses the links and the contents naturally to detect the topic community. Extensive experiments on nine real-world datasets with varying sizes and characteristics validate the proposed method outperforms other baseline algorithms in quality. Additionally simLPA integrated into the content is equivalent to LabelRank in efficiency, which is easy to handle large-scale information networks.

Changes of Plasma Tumor Necrosis Factor α and C-Reactive Protein Levels in Patients with Hypertension Accompanied by Impaired Glucose Tolerance and their Clinical Significance

Xiao, Qiang,Wang, Lan-Ping,Ran, Zhang-Shen,Zhang, Xin-Huan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8

Background: Chronic inflammation could affect the occurrence and development of malignant tumors. To explore the levels of tumor necrosis factor ${\alpha}$ (TNF-${\alpha}$) and C-reactive protein (CRP) in patients accompanied by impaired glucose tolerance (IGT) and their clinical significance. Materials and Methods: A total of 210 patients hospitalized in Affiliated Hospital of Taishan Medical University from Jun., 2013 to Dec., 2014 were selected, in which 92 cases were accompanied by IGT. Meanwhile, 80 randomly-selected healthy people by physical examination were as the control. The levels of routine biochemical indexes, plasma TNF-${\alpha}$ and CRP in all subjects were measured. Results: Both systolic and diastolic pressures in hypertension group and hypertension plus IGT group were significantly higher than in control group (p<0.01), but there was no statistical significance between these two groups (p>0.05). The levels of fasting plasma glucose (FPG) and blood glucose 2 h after taking glucose in hypertension plus IGT group were markedly higher than other groups (p<0.01). Homeostasis model assessment-insulin resistance (HOMA-IR), TNF-${\alpha}$ and CRP contents were on the progressive increase in control, hypertension and hypertension plus IGT groups, but significant differences were presented among each group (P<0.01). Hypertension accompanied by IGT had a significantly-positive association with CRP, TNF-${\alpha}$, FPG and blood glucose 2h after taking glucose. Conclusions: The levels of plasma TNF-${\alpha}$ and CPR in patients with hypertension accompanied by IGT increase significantly, indicating that inflammatory reaction in these patient increases, thus suggesting that these patients should be focused regarding cancer prevention.

Development of Origanum vulgare Cell Suspension Culture to Produce Polyphenols and the Stimulation Effect of Salicylic Acid Elicitation and Phenylalanine Feeding

Yan-Ping Li,Dao-Bang Tang,Xiao-Qiang Wang,Meng Wang,Qing-Feng Zhang,Yuan Liu,Bei-Yun Shen,Jiguang Chen,Zhongping Yin 한국생물공학회 2021 Biotechnology and Bioprocess Engineering Vol.26 No.3

Three types of calli were induced from Origanum vulgare (O. vulgare) aseptic seedlings, and the friable calli with white appearance and high growth rate were further screened and used to develop cell suspension culture to produce polyphenols. Murashige and Skoog (MS) medium with 3.0 mg/L Kinetin (KT) and 0.5 mg/L 2,4-dichlorophenoxy acetic acid (2,4-D) was suitable for both O. vulgare cells growth and polyphenols accumulation. To further enhance the polyphenols accumulation, O. vulgare cells were treated by phenylalanine (Phe) feeding and salicylic acid (SA) elicitation. Compared with the individual Phe feeding and SA elicitation, SA elicitation combined with Phe feeding showed a much better promotion effect on the polyphenols synthesis in O. vulgare cells, especially rosmarinic acid (RosA) accumulation. With the combined treatment of 200 μM SA and 100 μM Phe, total polyphenols content and yield were 41.36 mg/g and 752.93 mg/L, respectively. RosA content and yield reached 31.25 mg/g and 570.37 mg/L, which were 5.44 and 5.47 times that of the control. Furthermore, the total polyphenols extracted from the cultured cells treated by SA elicitation combined with Phe feeding displayed a much higher antioxidant capacity than that of untreated cells, meanwhile its 1,1-diphenyl-2- trinitrophenyl hydrazine (DPPH) and superoxide anion radical-scavenging activity were much stronger than that of vitamin C. What’s more, our results also showed that RosA was the principal contributor to the fine antioxidant capacity of the total polyphenols extracted from the SA and Phe treated cells. Our research indicated that SA elicitation combined with Phe feeding significantly improved the polyphenols yield and antioxidant capacity of the cultured O. vulgare cells, and therefore has a promising application prospect in natural polyphenols production.

Chinese herbal medicine for drug-induced liver injury in patients with HIV/AIDS: A systematic review of randomized controlled trials

Zhang Xiao-wen,Li Jing,Hou Wen-Bin,Jiang Yue,Zheng Ruo-Xiang,Xu De-hao,Shen Chen,Robinson Nicola,Liu Jian-Ping 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.1

Background: To explore the effectiveness and safety of Chinese herbal medicine (CHM) for drug-induced liver injury (DILI) in patients with human immunodeficiency virus (HIV)/acquired immunodeficiency syn- drome (AIDS). Methods: A systematic search was made of eight databases (Pubmed, Cochrane Library, Web of Science, Embase, CNKI, Wanfang, VIP, Sinomed) and two trial registries (WHO ICTRP, ClinicalTrials.gov) from in- ception to September 2022. The effect size was presented as risk ratio (RR) or mean difference (MD) with their 95% confidence interval (CI). The Cochrane Risk of Bias and Grading of Recommendations, Assess- ment, Development and Evaluations (GRADE) tools were used for quality appraisal. Results: Ten randomized controlled trials (RCTs) involving 732 participants were included. Comparing CHM alone with routine treatment, the CHM group showed lower aspartate aminotransferase (MD = -11.47 U/L, 95%CI[-13.05, -9.89], low certainty), lower alanine aminotransferase (MD = -2.68 U/L, 95%CI[-4.27, - 1.08], low certainty), lower total bilirubin (MD = -4.31 mmol/L, 95%CI[-5.66, -2.96], low certainty), lower bilirubin direct (MD = -3.19 mmol/L, 95%CI[-3.87, -2.51], low certainty), and higher effective rate (assessed by symptoms and liver indicators) (RR = 1.13, 95%CI[1.06, 1.20], low certainty). A significant difference was also found in CHM plus routine treatment versus routine treatment in the previous outcomes. No signif- icant difference was found on helper T cells among these comparisons. Only one RCT reported safety of CHM and found no adverse reaction during the trial. Conclusions: CHM may improve the liver function indices and effective rate for HIV/AIDS patients with DILI. However, the sample size was small and quality was low. Larger-samples of high-quality trials are needed.

The Effect of Postural Correction and Subsequent Balloon Inflation in Deformity Correction of Acute Osteoporotic Vertebral Fractures

Liu, Hai-Xiao,Xu, Cong,Shang, Ping,Shen, Yue,Xu, Hua-Zi The Korean Neurosurgical Society 2014 Journal of Korean neurosurgical society Vol.55 No.6

Objective : To determine deformity correction by postural correction and subsequent balloon inflation in acute vertebral compression fractures (OVCFs) and to examine the effect of bone mineral density on deformity correction. Methods : A totol of 50 acute OVCFs received balloon kyphoplasty. Lateral radiographs were taken and analyzed at five different time points : 1) preoperative, 2) after placing the patient in prone hyperextended position, 3) after balloon inflation, 4) after deposition of the cement, and 5) postoperative. All fractures were analyzed for height restoration of anterior (Ha), middle (Hm) and posterior (Hp) vertebra as well as Cobb angle and Kyphotic angle. The bone mineral density (BMD) of lumbar spine was measured by dual-energy X-ray absorptiometry. According to the T-score, the patients were divided into two groups which were osteoporosis group and osteopenia group. Results : Postoperative measurements of Ha, Hm and the Cobb angle demonstrated significant reduction of 4.62 mm, 3.66 mm and $5.34^{\circ}$ compared with the preoperative measurements, respectively (each p<0.05). Postural correction significantly increased Ha by 5.51 mm, Hm by 4.35 mm and improved the Cobb angle by $8.32^{\circ}$ (each p<0.05). Balloon inflation did not demonstrate a significant improvement of Ha, Hm or the Cobb angle compared with baseline prone hyperextended. Postural correction led to greater improvements of Ha, Hm and Cobb angle in osteoporosis group than osteopenia group (each p<0.05). Conclusion : In acute OVCFs, the height restoration was mainly attributed to postural correction rather than deformity correction by balloon inflation. BMD affected deformity correction in the process of postural correction.

A Survey of the Geographic Distribution of Ophiocordyceps sinensis

Yi Li,Xiao-Liang Wang,Lei Jiao,Yi Jiang,Hui Li,Si-Ping Jiang,Ngarong Lhosumtseiring,Shen-Zhan Fu,Cai-Hong Dong,Yu Zhan,Yi-Jian Yao 한국미생물학회 2011 The journal of microbiology Vol.49 No.6

Ophiocordyceps sinensis is one of the best known fungi in Traditional Chinese Medicine. Many efforts have been devoted to locating the production areas of this species resulting in various reports; however, its geographic distribution remains incompletely understood. Distribution of O. sinensis at the county level is clarified in this work based on both a literature search and fieldwork. More than 3600 publications related to O. sinensis were investigated, including scientific papers, books, and online information. Herbarium specimens of O. sinensis and field collections made by this research group during the years 2000-2010 were examined to verify the distribution sites. A total of 203 localities for O. sinensis have been found, of which 106 are considered as confirmed distribution sites, 65 as possible distribution sites, 29 as excluded distribution sites and three as suspicious distribution sites. The results show that O. sinensis is confined to the Tibetan Plateau and its surrounding regions, including Tibet, Gansu, Qinghai, Sichuan, and Yunnan provinces in China and in certain areas of the southern flank of the Himalayas, in the countries of Bhutan, India and Nepal, with 3,000 m as the lowest altitude for the distribution. The fungus is distributed from the southernmost site in Yulong Naxi Autonomous County in northwestern Yunnan Province to the northernmost site in the Qilian Mountains in Qilian County, Qinghai Province, and from the east edge of the Tibetan Plateau in Wudu County, Gansu Province to the westernmost site in Uttarakhand, India. The clarification of the geographic distribution of O. sinensis will lay the foundation for conservation and sustainable use of the species.