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        Synthesis and Characterization of Aqueous Chitosan-polyurethanes Dispersion for Textile Applications with Multipurpose Performance Profile

        Shazia Muzaffar,Ijaz Ahmad Bhatti,Mohammad Zuber,Haq Nawaz Bhatti,Muhammad Shahid 한국섬유공학회 2018 Fibers and polymers Vol.19 No.3

        As the use of high performance textiles has grown, the need for chemical finishes to provide the fabric properties required in the special applications has grown accordingly. In this project, a series of water dispersible polyurethanes dispersion (CS-PUs) with multipurpose performance profile was developed using isophorone diisocyanate (IPDI), polyethylene glycol (PEG), 2,2-dimethylol propionic acid (DMPA) and chitosan (CS) for textile applications. In two step synthesis process, NCO functional PU prepolymers prepared by reacting IPDI, PEG, and DMPA were extended with varying molar quantities of chitosan followed by structural characterization through FTIR. The prepared CS-PU dispersions were applied onto the dyed and printed poly-cotton blend fabrics. The performance behavior of the treated fabric in terms of crease recovery, tear strength, tensile strength, and antibacterial properties was evaluated by applying standard test methods. These investigations show that the CS-PU dispersions can be applied as antibacterial textile finishes with significant improvement in the physical and mechanical properties of poly-cotton fabrics.

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        Sargassum swartzii extracts ameliorate memory functions by neurochemical modulation in a rat model

        Pirzada Jamal Ahmed Siddiqui,Adnan Khan,Nizam Uddin,Saima Khaliq,Munawwer Rasheed,Shazia Nawaz,Ahsana Dar,Muhammad Hanif 한국식품과학회 2017 Food Science and Biotechnology Vol.26 No.4

        Recently, considerable attention has been paid to drug exploration from natural sources for treating memory loss, a major manifestation of various neurodegenerative diseases. Increasing evidences implicate brain serotonin metabolism in learning and memory, supporting the notion that targeting 5-HT (5-hydroxytryptamine) and its receptors would be beneficial in the treatment of cognitive disorders. In the present study, behavioral and neurochemical effects were examined following administration of Sargassum swartzii extracts in albino Wistar rats. Increase in spatial working memory and recognition memory was exhibited by the seaweed-treated rats as compared to controls. Plasma tryptophan, brain 5-HT, and 5-hydroxyindoleacetic acid levels were measured using HPLC–ECD, and a significant increase in brain 5-HT metabolism was observed in the seaweed-treated rats. The increase in memory functions following repeated administration of S. swartzii extracts is suggested to be due to the increased serotonergic neurotransmission in the brain of seaweed-treated rats.

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