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Sevil Albayrak,Nurcan Silahtarlıoğlu 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.1
In this study evaluated the phenolic, flavonoid contents, antioxidant, antimicrobial and cytotoxic activities of Achillea coarctata extract. Also, chemical compositions of the extract and essential oil were analyzed by HPLC and GC–MS. The antioxidant activity of the extract was determined with phosphomolybdenum, DPPH (2,2-diphenyl-1-picrylhydrazyl radical scavenging), hydrogen peroxide scavenging, β-carotene bleaching activity, Fe+2-ion reducing power (FRAP) and cupric ion (Cu2+) reducing antioxidant capacity (CUPRAC) assays. The extract and essential oil were investigated for antimicrobial activities against 15 species of microorganisms. The extract has been only found to be effective against Klebsiella pneumoniae, while essential oil was effective against Listeria monocytogenes, K. pneumoniae, Bacillus cereus, Streptococcus pneumoniae and Candida albicans. The cytotoxic activity of the extract on MCF7 (human breast cancer cell line, ATCC HTB-22) and NIH/3T3 (mouse embryo fibroblast cells, ATCC CRL-1658) was studied by MTT assay. The extract showed cytotoxic activity on MCF-7 cell line.
Sevil Albayrak,Biriz Çakır,Fatma Nisancı Kılınç,Ozge Vergili,Yurdagül Erdem 한국간호과학회 2018 Asian Nursing Research Vol.12 No.4
Purpose: The purpose of this study is to investigate adaptation, validity, and reliability of the Turkish version of the Child and Adolescent Social Support Scale for Healthy Behaviors (CASSS-HB). Methods: The CASSS-HB was translated using translation and back-translation. This was a methodological study conducted with 860 students (11-14 years old). Content and construct validity were assessed to test the validity of the CASSS-HB. Exploratory and confirmatory factor analysis of the scale was performed and the reliability of the scale over time (the test-retest method) was examined. Results: Psychometric analyses of the Turkish version of the CASSS-HB indicate high reliability and good content and construct validity. Conclusions: It can be seen that the items comprising the scale appear to be acceptably capable of measuring the variable of social support in terms of healthy behavior in children and adolescents. Healthcare professionals can thus use the scale for determining the degree of social support students of the ages 11-14 receive in terms of developing healthy behavior.