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김승재,박경호,김용이 한국운동역학회 1999 한국운동역학회지 Vol.9 No.1
Mammals, including human, store much of energy needed to run with elastic structures of foot and leg. The important structures to store the elastic strain energy in human body are Achilles tendon and foot arch, however, the foot arch is unique structure in human without the other mammals between the two. Therefore, the purposes of this study were firstly to review comprehensively the literatures on the studies on the functional roles, clinical results and practical applications of the foot arch, and secondly to propose the future directions of research on the foot arch based on the review. To do so, this review are described to divide into four categories; 1) deformity of the foot arch and injury,, 2) ligament, muscle and tendon to form the foot arch, 3) determination of arch height, 4) orthotics and sports shoe for the foot arch types. As a result of reviewing comprehensively the research on the foot arch on functional, clinical and practical aspects, abnormal feet such an low-arched foot and high-arched foot are shown to have significant relationship with injuries during walking and running. To overcome this it is required to understand the muscles and ligaments to form the foot arch throughly, and to be able to reconstruct the abnormal foot arch clinically based on the information. In the practical aspects, it is expected to perform healthy sports activities without any injury with making the proper orthotics and sports shoe according to the foot arch types by determining the arch height at dynamic situation rather than static situation. For the future directions it will need to develop an integrated model to explain both static and dynamic characteristics of the foot and to make theoretical study throughly on the foot arch using the model. Based on the integrated model proposed it will need to develop clinical treatment to prevent walking injury and to make practical study on the development of individualized orthotics and sports shoe according to foot characteristics.
Korean Translation and Linguistic Validation of Urgency and Overactive Bladder Questionnaires
Seung-Ee Kim,Hyo Serk Lee,Ha Na Lee,Seo Yeon Lee,Min Soo Choo,Min Gu Park,Ji Yun Chae,Seung-June Oh,Sung Yong Cho 대한배뇨장애요실금학회 2020 International Neurourology Journal Vol.24 No.1
Purpose: Given the importance of evaluating the severity of overactive bladder (OAB) symptoms and outcomes after treatment, several questionnaires have been developed to evaluate OAB patients. However, only limited questionnaires are available in Korea for use with Korean patients. Therefore, this study aimed to develop Korean versions of OAB questionnaires through a rigorous linguistic validation process. Methods: The Indevus Urgency Severity Scale, Urgency Perception Scale, Urgency Severity Scale, and Patient Perception of Intensity of Urgency Scale underwent translation and linguistic validation. The linguistic validation procedure consisted of permission for translation, forward translations, reconciliation, back-translation, cognitive debriefing, and proofreading. Two independent bilingual translators translated the original version of each questionnaire, and a panel then discussed and reconciled the 2 initial translations. Next, a third independent bilingual translator performed a backward translation of the reconciled version into English. Five Korean patients diagnosed with OAB were interviewed for cognitive debriefing. Results: Each item of the questionnaires was translated into 2 Korean versions in the forward translation process. Terms such as ‘urgency’ and ‘wetting’ were translated into ordinary language by the translators and adjusted by the panel members to more conceptually equivalent terms in a medical context. In the back-translation process, the panel made a few changes regarding details based on a comparison of the back-translated and original versions. During the cognitive debriefing process, 5 patients provided a few pieces of feedback on the naturalness of the wording of the questionnaires, but generally agreed on the translated terms. Conclusions: In this study, the panel produced a successful linguistic validation of Korean versions of multiple OAB questionnaires, which can be utilized to evaluate the severity and treatment outcomes of OAB.
A Korean Child with Schaaf-Yang Syndrome Presented with Hearing Impairment: A Case Report
Seung Hoon Lee,Seung Han Shin,Jung Min Ko,김보람,Hyeon Sae Oh,Man Jin Kim,Seul Gi Park,Ee Kyung Kim,Han Suk Kim 대한신생아학회 2022 Neonatal medicine Vol.29 No.3
Schaaf-Yang syndrome (SYS) is a rare genomic imprinting disorder caused by truncating mutations in the paternally derived MAGE family member L2 (MAGEL2) allele. It is also responsible for Prader-Willi syndrome, characterized by neonatal hypotonia, developmental delay, intellectual disability, respiratory distress in early infancy, and arthrogryposis. More than 250 individuals with approximately 57 different molecular variants have been reported since 2013, but the phenotype-genotype association in SYS is not yet fully understood. Here, we describe the case of a Korean patient diagnosed with SYS harboring a mutation in the paternal allele of MAGEL2: c.2895G>A, resulting in a protein change of p.Trp965*. The patient’s phenotype included respiratory distress, arthrogryposis, hypotonia, and feeding difficulty in the early neonatal period. Mild renal dysfunction and hearing impairment were observed during infancy.
Seung-Hyun Shin,Hyo-Won Kim,Younghwa Jung,Seung Han Shin,Ee Kyung Kim,Han Suk Kim 대한신생아학회 2016 Neonatal medicine Vol.23 No.4
Purpose: The prevalence of antibiotics resistant bacterial infection among preterm infants has been increased due to indeliberate use of prophylactic broad spectrum antibiotics. The objective of this study was to assess the effectiveness of restricted usage of prophylactic antibiotics by comparing the incidence of culture proven early onset sepsis (EOS). Methods: This was a retrospective cohort study for extremely low birth weight infants who were born in Seoul National University Children’s Hospital during 2009-2014. The groups were divided into two periods, from 2009 to 2011 (period I) and from 2012 to 2014 (period II) based on the implementation on quality improvement activity since 2012. The indication of prophylactic antibiotics were; 1) umbilical vein catheter (UVC) insertion for resuscitation in delivery room, 2) prolonged preterm premature rupture of membrane >18 hours, 3) maternal fever during labor or sustained septic amniotic fluid. The incidence of EOS and the rate of empirical antibiotics usage were compared between two periods. Results: A total of 245 infants were admitted to the neonatal intensive care unit during the study period. Baseline demographics and clinical characteristics were similar between two periods except UVC insertion rate. The rate of empirical antibio- tics usage significantly decreased in period II (71.1% for period I vs. 56.4% for period 2, P=0.022). Incidence of EOS was not different between two periods whether pro- phylactic antibiotics use or not. Conclusion: Quality improvement for reducing prophylactic antibiotics use may be effective to reduce a use of antibiotics without increasing EOS.
30Nm³/h급 합성가스 초고순도 정제시스템 개발 현황
이승종(Seung Jong 1ee),윤덕규(Deok-Kyu Youn),김혜수(Hye Soo Kim),이철호(Chul-ho Lee),이재영(Jae Young Lee),김미정(Mi Jeong Kim) 한국환경에너지공학회 2022 한국열환경공학회 학술대회지 Vol.2022 No.2
합성가스 기반 수소생산 기술은 석유 코크스, 석탄, 폐기물 동의 저급자원을 가스화하여 합성가스를 생산하고 이를 정제, 전환 및 분리하여 수소를 생산하는 기술로, 원유 정제 후 남는 부산물인 석유 코크스롤 가스화하여 수소를 생산하기 위한 일환으로 기 술개발을 수행하고 있다. 석유 코크스를 이용하여 안정적으로 수소를 생산하기 위해서는 가스화룔 통해 생산된 합성가스에 함유된 H2S, COS, NHa 둥과 같은 산성가스 및 염기성 가스를 0.1 ppm 이하로 제거하는 초고순도 정제가 필요하다. 본 연구팀에서는 석유 코크스 가스화를 통해 수백~수천 ppm으로 발생되는 H2S와 COS를 제거하는 설비와 수~수십 ppm 이 하로 발생되는 NH3 동의 미 량가스몰 제거하는 30Nm³/h 규모의 설비를 설계하였으며, 석유 코크스 가스화를 통해 생산된 합성가스를 초고순도로 정제하기 위한 시스템을 구축하여 운전 중에 있다.
( Seung-ju Lee ),( Dae San Yoo ),( Song-ee Kim ),( Sang Eun Lee ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1
Background: Excess sebum production contributes to the development of several skin diseases including acne vulgaris. Argon and nitrogen plasma pulses have been shown to induce coagulation of sebaceous glands in rat skin. Objectives: To evaluate the effect of argon and nitrogen plasma pulses on sebum production in oily human skin in vivo and in human sebocytes in vitro. Methods: Fifteen healthy individuals (aged 19-40 years) who were determined to have oily skin by Sebumeter measurement were treated with argon and nitrogen plasma pulses 3 sessions in a 1-week interval. UV images and objective measurements of sebum level and sebum excretion were performed at baseline and 2, 4, 8 weeks post-treatment. In two volunteered individuals, 2 mm skin biopsies were performed before and after treatments. Effects of argon and nitrogen plasma pulses on lipogenesis and proliferation of human SZ95 sebaceous were evaluated. Results: Argon and nitrogen plasma pulses induced a significant reduction of casual sebum level (29% at forehead and 53% at zygoma) and sebum excretion rate (25% at forehead and 40% at zygoma) at week 8. Biopsy samples revealed the reduction of Ki67 in basal sebaceous gland cell and epithelial duct at week 2. Adverse effects were minimal. Argon and nitrogen plasma pulses suppressed testosterone and linoleic acid treatment-induced lipogenesis and proliferative ability in cultured sebocytes. Conclusion: Argon and nitrogen plasma pulses can suppress sebaceous lipogenesis in vivo and in vitro.