http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Triamcinolone Acetonide가 배양 켈로이드 섬유아세포의 G1 세포주기 관련 유전자 발현에 미치는 영향
설정현,우상현,백원기,서성일,서민호 大韓成形外科學會 1998 Archives of Plastic Surgery Vol.25 No.2
The effect of triamcinolone acetonide(TA) on the expression of Gl related genes was investigated the cultured keloid fibroblast. The addition of TA to the culture medium resulted in growth inhibition of keloid fibroblast. TA reduced the expression of cyclin A, B, E and cyclin dependent kinase(CDK) 2 mRNA, but unexpectedly, the expression of cyclin C, Dl and CDK4 mRAN was not affected significantly as compared with those of normal fibroblast. Expressions of p16, p21 and p27, the wellestabilished CDK-inhibitors, were also investigated. The level of p16 was not detected in both normal and keloid fibroblasts and the expression of p27 was significantly decreased in keloid fibroblast. The expression of p21 was dramatically increased in keloid fibroblast but not significantly changed in normal fibroblast. Also the expressions of p53 and pRb, the well known tumor suppressor genes, were increased by the addition of TA. These data suggested that the observed growth inhibitory effect of TA may be related to transcriptional inactivation of cyclin A, B, E and CDK2 and to the transcriptional activation of p21, but the mechanisms of unchanged expression of cyclin C, Dl and CDK4 mRNA remain to be elucidated.
Missile Radome Error Compensation Using Modified Interacting Multiple Model Kalman Filter
Seul-Ki Han,Sejoon Ahn,Won-Sang Ra,Jin Bae Park 제어로봇시스템학회 2014 제어로봇시스템학회 국제학술대회 논문집 Vol.2014 No.10
This paper addresses the compensation problem of the missile radome aberration error using the interacting multiple model (IMM) algorithm. To compensate the radome error, the proposed method estimates the radome slope by applying the modified IMM algorithm. In the proposed approach, the mode probability update in the IMM algorithm is redefined for improving performance of the radome slope estimation by reflecting the recent tendency of the radome slope hypotheses. This is enabled by utilizing the new weighting function including previous information of likelihood function and mode probability during certain period. Besides, by designating boresight error and LOS rate as the state for the system model, the linear estimation technique is used instead of the nonlinear estimation method. Therefore, the proposed method is suitable for the real-time implementation due to the linear filter structure. Through the simulation results on the typical engagement missile-target scenario, the reliability and performance of the proposed radome slope estimator is evaluated.
Practical Direction of Arrival Estimator using Constrained Robust Kalman Filtering
Seul-Ki Han,Won-Sang Ra,Jin Bae Park 제어로봇시스템학회 2013 제어로봇시스템학회 국제학술대회 논문집 Vol.2013 No.10
This paper proposes a linear estimation theory based direction of arrival (DOA) estimator to guarantee highperformance and computational efficiency. To do this, state-space system is derived from the linear prediction relation of the sinusoidal acoustic signal. Since it contains uncertain measurement matrix, the recently developed non-conservative robust Kalman filter (NCRKF) can be applied to compensate the performance degradation by the uncertain measurement matrix. However, unfortunately, the statistical information used in NCRKF scheme may not be precise in actual situation and it leads to the performance degradation. Therefore, in this paper, constrained NCRKF (CNCRKF) is presented to develop practical DOA estimator. It adopts constraint condition derived from the relation between target states to solve the performance degradation problem by the incorrect statistical information. The performance of the proposed solution is demonstrated by the computer simulation.