Halothane 마취중 Vecuronium과 Pancuronium 투여가 심혈관계 및 회복시간에 미치는 영향

길기진,김종열,이정은,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

This study was taken to abserve the effect on cardiovascular response and recovery time with pancuronium and vecuronium. The patients was composed of 20 healthly both sex adults who belong to class I of ASA physical status. Vecuronium 0.1mg/kg(N=10) and pancuronium 0.1mg/kg(N=10) was injected independently at 20 minutes after intubation by succinylcholine 1mg/kg and thiopental sodium. The results were as follow. 1. There were not a significant difference in arterial blood pressure and pulse rate before and after vecuronium injection. 2. After pancuronium administration, arterial blood pressure was not significant change but pulse rate showed significant increasing. 3. In the recovery time when T_1 was recovered to 25% after administration of muscle relaxants respectively, there were 26±7.2 min, vecuronium and 67±11.2 min, in pancuronium. 3. EKG was not change before and after vecuronium.

흡연 및 비흡연 정신분열증 환자간의 인지 기능과 치료 반응의 차이

남궁기,민성길,이희상,조현상,김세주 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.4

연구 배경 : 본 연구는 정신분열증 환자에서 흡연 여부에 따라 정신분열증 환자군의 정신과적 과거력 및 현재 증상, 치료 반응과 인지 기능 등에 어떤 차이가 있는 지를 알아보려는 것이다. 연구 방법 : 정신분열증 환자 중 36명의 흡연군과 31명의 비흡연군을 연구 대상으로 하였다. 현재의 증상을 평가하기 위해서 양성 및 음성 증상 척도(Positive & Negative Syndrome Scale) 및 전반적 기능 평가 척도(Global Assessment Scale)를 상용하였고, 추체외로계 부작용을 추체외로계 부장용 평가척도(Rating Scale for Extrapyramidal Side Effects)로 측정하였다. 흡연군과 비흡연군의 인지 기능을 평가하기 위해 비엔나 검사 중 SPM(Standard Progressive Matrices), Cognitron 및 FFA(Flicker Fusion Analyzer) 검사를 실시하였다. 연구 결과 : 1) 흡연군과 비흡연군에 비해 유병 기간이 유의하게 길었음에도 불구하고, 입원 시의 증상 정도(PANSS 총점)가 유의하게 낮았고, 기능 정도(GAS 점수) 역시 유의하게 높았다. 2) 정신분열증의 치료 반응에 영향을 미칠 것으로 생각되는 나이와 유병 기간을 통제한 상태에서 흡연여부에 따른 치료 반응의 차이를 검증해 본 결과, 흡연 여부에 따른 일일 약물 사용량, 추체외로계 부작용 및 증상 호전율(PANSS 호전율)이나 기능 호전율(GAS 호전율)에 유의한 차이는 없었다. 또한 인지 기능에 영향을 미칠 것으로 생각되는 나이, 유병 기간, 항전신병약물 용량 및 증상의 정도를 통제한 상태에서 흡연 여부에 따른 인지 기능의 차이를 검증해 본 결과, 흡연 여부에 따른 SPM 값, COG-R 및 FFA 갑의 차이는 없었다. 3) 흡연군 내에서 흡연 정도와 치료 반응 및 인지 검사 점수와의 관계를 알아보기 위해, 나이와 유병 기간 요인을 통제한 상태에서 일일 평균 흡연량과 여러 임상 척도와의 상관 관계를 분석해 보았다. 그 결과 일일 흡연량과 증상 호전율(PANSS 호전율) 이나 기능 호전율(GAG 호전율) 사이에 통계적으로 유의한 상관 관계를 보였다. 그러나 총 흡연 기간은 치료 반응 및 인지 기능과는 통계적으로 유의한 상관 관계를 보이지 않았다. 결 론 : 이상의 결과를 종합해 보면 흡연 정신분열증군은 비흡연 정신분열증군에 비해 입원 시 증상이 경미하고 기능이 좋으며, 흡연 정신분열증군에서는 흡연량이 많을수록 치료 시 증상 및 기능이 호전율이 높다고 할 수 있다. 그러나 흡연군에서 일일 약물 사용량이 높다거나, 추체외로계 부작용이 덜 나타난다거나 지능 저하가 덜하다는 이전의 연구 결과들은 입증되지 않았다. Objectives : The purpose of this study was to examine the differences of past histories, current symptoms, treatment responses and cognitive and functions between smoking and nonsmoking schizophrenic patients. Methods : The subjects were composed of 67 schizophrenic patients including 36 smokers and 31 non-smokers. They were examined by psychiatric history checklist, Simpson and Angus's rating scale for extrapyramidal side effects, positive & negative syndromes scale(PANSS), global assessment scale(GAS), and Vienna test including Standard Progressive Matrices(SPM), Cognitron, and Flicker Fusion Analyzer(FFA). Results : The results were as follows : 1) Although the duration of illness of smokers was longer than that of non-smokers, the smokers had significantly higher score of GAS and significantly lower score of PANSS than non-smokers at admission. 2) With effects of age and duration of illness controlled, there were no differences of mean dosage of neuroleptics, extrapyramidal side effects, PANSS improvement rate and GAS improvement rate between both groups. 3) With effect of age, duration of illness, and total PANSS score controlled, there were no differences of score of SPM, cognitron, and FFA. 4) In smokers, the PANSS improvement rate and the GAS improvement rate were positively correlated with mean number of daily smoked cigarettes, with effects of age and duration of illness controlled. Conclusions : In schizophrenic patients, smokers had less severe symptoms than non-smokers. In smokers, the PANSS improvement rate and the GAS improvement rate were positively correlated with mean number of daily smoked cigarettes. But Smokers were not proven to have received higher dosage of neuroleptics, to have lower extrapyramidal side effects, or to have less severe impairment of cognitive function.

Succinylcholine으로 유발된 Fasciculation과 Myalgia에 대한 Diazepam과 d-tubocurarine 전처치의 비교효과

최세진,길기진,이정은 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.2

Succinylcholine-induced muscle pain well documented. It is common to use subparalyzing dose of a non-depolarizing muscle relaxant before succinylcholine and accepted in clinical practice forpreventing of succinylcholine-induced fasciculation and it's associated sequalae. But it is needed to give large dose of succinylchcline to offer adeguate relaxation for tracheal intubation in these pretreated cases. This present study was undertaken to compare the effect of diazepam with d-tubocurarine on succinylcholine induced side effects. Sixty cases were studied if four different groups. In 1st group : no pretreatment, 2nd group : diazepam(0.05mg./kg.), 3rd group : diazepam(0.1 mg./kg.), 4th group : d-Tc.(0.05mg./kg.). The following results were obtained : 1. Diazepam pretreatment groups had no significant changes for the prevention of muscle fasciculation following succinylcholine compare to control group, but prevention of muscle fasciculation by d-Tc. pretreatment were significant. 2. Conditions for intubation were excellent in all groups. 3. In the prevention of muscle pain, there was no significant difference between the control and diazepam pretreatment group but significant difference between the control and d-Tc. prtreatment. 4) There was no specific relationship between muscle fasciculation and muscle pain.

지주막하강내에 각종 진통제 주입이 수술후 진통효과에 미치는 영향

최세진,길기진 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

Intrathecal administration of opioid for pain relief became popular since Pert, et al (1973) reported the opioid receptor in spinal cord. It is obious now morphine has prolonged and profound analgesic effect with few complication but Meperidine has relatively shorted and profound analgesic effect. This study was taken to observe on effect of postoperative pain relief after intrathecal morphine (0.3mg) and meperidine (3mg) injection. We selected 40 patients, divided into 2 group to compare the effects respectively. Group Ⅰ : 20 patient receiving 0. 3mg intrathecal morphine. Group Ⅱ : 20 patient receiving 3mg intrathecal meperidine The results are as follow. 1) Duration of analgesia of group I was 23.5±5.6 hrs. and group Ⅱ 8.1±2.3 hrs. 2) The side effects of group I and Ⅱ were similar, but pruritis was noted twice as much group I than in group Ⅱ.

사상체질론의 정신의학적 타당성에 대한 연구

민성길,김동기,박진균,전세일 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.3

연구목적 : 건간한 의대상 312명과 신경증적 장애를 가진 환자 288명을 대상으로 하였다. 사상체질의 구별은 노정우 및 김달래 두 전문가에 의한 판정, 그리고 경희의대 사상체질 설문지(QSCC Ⅱ)에 의한 판정 등 3가지 방법에 의하였다. 연구 대상에게 정신과적 증상척도(SCL-90), 체질특성척도 및 성격척도를 사용하여 자가 평가하게 하였다. 각종 척도들의 타당도와 신뢰도는 입증되었다. 이 척도들을 통계적으로 분석하고 고전적 설명과 어느 정도 일치하는 지를 검토하였다. 연구결과 : 1) 3가지 분류방법간에 차이가 컸었다. 그 중 전문가의 직접적 면담에 의한 감별보다 QSCCⅡ 설문지형이 비교적 감별력이 컸다. 3) QSCCⅡ가 감별력이 비교적 크다고 하더라도 그 결과가 소음군의 대인공포-강박증, 불면-식용상실, 무력-예민-소화기-한기-피부증후군 그리고 정력부족등 신경증적 증상과 소극-비사교적, 내향형 성격 및 이성적 성격특징 등 몇가지 특징을 감별하는 데에만 비교적 유의하였고, 태음군의 특정인 독특한 신념, 온기, 활달-사교적 성격에 대해서는 부분적으로 그 특징을 감별하였다. 또한 소양군의 활달-사교형 성격과 감정형 성격의 특징 등은 극히 부분적으로 감별하였다. 결 론 : 이러한 결과는 현존하는 사상체질 구분방법에 일치점이 결여되어 있다는 것, 각종척도를 사용한 결과는 사상체질에 관한 고전적 설명을 부분적으로만 입증하고 있다는 것, 따라서 사상체질구분에 대한 향후보다 객관적인 연구가 필요하다는 것을 시사한다. Object : This study is to examine the validity of constitutional classification of Sa-sang medical theory. This theory classifies the human constitution to 4 types according to classical oriental philosophy on yin and yang. Subjects and Method : Subjects were 312 medical students and 288 neurotic patients with diagnosis of neurotic, stress related and somatoform disorders and minor depressive episodes according to ICD-10. Medical students were classified to 4 Sa-sang Constitution Classification(QSCCⅡ). For assessmnent of symptoms and signs, Korean version of SCL-90, a constitution scale and personality scale which were designed for this study were used. These instruments were found to be reliable and valid through statistical analysis. Subjects were asked to rate these scales. The data were analysed with factor analysis and factor scores were compared among 4 Sa-sang constitutions by ANOVA and t-test. The data from patient group were analysed with factor analysis and the results were compared with the Sa-sang medical theory. Results : Results of classification by 3 ways were inconsistent showing a significant difference among them. Among them, QSCCⅡ was most reliable. In QSCC Ⅱ, only the factor scores of factors of homophobia-obsession, weakness-sensitiveness-indigestion-chillness-skin syndrome, sexual weakness, passive-unsociable personality, introverted personality and rational, personality, were significantly high in So-um (small yin) group of medical students. A factor of warmnes and active-sociable personality were significantly high in Tae-um(big yin)group. Also active-sociable and effective pesonality was partly related with So-yang(small yang)group. Conclusion : These results suggest that those present classification methods inconsistent, that these methods are proving only parts of Sa-sang medical theory, and that objective and scientific studies are needed for reliability and validity of Sa-sang medical theory.

A Study on the State of EEG in high Macrate Using Wavelet Transform and Power Spectrum Analysis

Se-Kee Kil,Dong Fan Shen,Eung-Hyuk Lee,Young-Sear Kim,Hong-Ki Min,Young-Bae Park,Toshi-Hiro Nishimura,Seung-Hong Hong 대한전자공학회 2006 ICEIC:International Conference on Electronics, Inf Vol.2006 No.6

Measurement of Arterial Pulse Wave at the Temple Using PZT Piezo Sensor

Se Kee Kil,Young Hwan Han,Eung Hyuk Lee,Young Bae Park,heung Ho Choi,Hong Ki Min,Seung Hong Hong 대한전자공학회 2004 ICEIC:International Conference on Electronics, Inf Vol.2004 No.8

A Study on the Measurement of Diagnosis Parameter by Feature Point Recognition of Radial Pulse

Se Kee Kil,Seong Hyun Han,O Sang Kwon,Seung Hwan Park,홍승홍 대한전자공학회 1998 ICEIC:International Conference on Electronics, Inf Vol.1 No.1

Recognition of Power Spectrum Rate of Alpha Wave in EEG using Wavelet Transform

Se-Kee Kil,Young-Seo Kim,Eung-Hyuk Lee,Hong-Ki Min,Toshi-Hiro Nishimura,Seung-Hong Hong 대한전자공학회 2006 ITC-CSCC :International Technical Conference on Ci Vol.2006 No.3

Arterial Pulse and ECG Measurement System Using IEEE 802.15.4/Zigbee Wireless Network and PDA

Se Kee Kil,Dong Fan Shen,Eung Hyuk Lee,Hong Ki Min,Young Bae Park,Seung Hong Hong 대한전자공학회 2005 ITC-CSCC :International Technical Conference on Ci Vol.2005 No.3