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      • KCI등재

        Double versus single cartridge of 4% articaine infiltration into the retro-molar area for lower third molar surgery

        Sawang, Kamonpun,Chaiyasamut, Teeranut,Kiattavornchareon, Sirichai,Pairuchvej, Verasak,Bhattarai, Bishwa Prakash,Wongsirichat, Natthamet The Korean Dental Society of Anesthsiology 2017 Journal of Dental Anesthesia and Pain Medicine Vol.17 No.2

        Background: There are no studies regarding 4% articaine infiltration injection into the retro-molar area for an impacted lower third molar (LITM) surgery. This study aimed to evaluate the efficacy of infiltration using 1.7 ml (single cartridge: SC) of 4% articaine versus 3.4 ml (double cartridges: DC) of 4% articaine with 1:100,000 epinephrine in LITM surgery. Method: This study involved 30 healthy patients with symmetrical LITM. The patients were assigned to receive either a DC or SC of 4% articaine with 1:100,000 epinephrine as a local anesthetic for each operation. Onset, duration, profoundness, need for additional anesthetic administration, total volume of anesthetic used, vitality of the tooth, and pain score during operation were recorded. Results: The DC of 4 % articaine had a significantly higher success rate (83.3%) than did the SC (53.3%; P<0.05). The duration of soft tissue anesthesia was longer in the DC group. The intra-operative pain was higher in the SC group with a significant (P < 0.05) requirement for a supplementary local anesthetic. Conclusion: We concluded that using DC for the infiltration injection had a higher success rate, longer duration of anesthesia, less intra-operative pain, and a lower amount of additional anesthesia than SC in the surgical removal of LITM. We recommend that a DC of 4% articaine and a 1:100,000 epinephrine infiltration in the retro-molar region can be an alternative anesthetic for LITM surgery.

      • KCI등재

        Pain measurement in oral and maxillofacial surgery

        Sirintawat, Nattapong,Sawang, Kamonpun,Chaiyasamut, Teeranut,Wongsirichat, Natthamet The Korean Dental Society of Anesthsiology 2017 Journal of Dental Anesthesia and Pain Medicine Vol.17 No.4

        Regardless of whether it is acute or chronic, the assessment of pain should be simple and practical. Since the intensity of pain is thought to be one of the primary factors that determine its effect on a human's overall function and sense, there are many scales to assess pain. The aim of the current article was to review pain intensity scales that are commonly used in dental and oral and maxillofacial surgery (OMFS). Previous studies demonstrated that multidimensional scales, such as the McGill Pain Questionnaire, Short form of the McGill Pain Questionnaire, and Wisconsin Brief Pain Questionnaire were suitable for assessing chronic pain, while unidimensional scales, like the Visual Analogue Scales (VAS), Verbal descriptor scale, Verbal rating scale, Numerical rating Scale, Faces Pain Scale, Wong-Baker Faces Pain Rating Scale (WBS), and Full Cup Test, were used to evaluate acute pain. The WBS is widely used to assess pain in children and elderly because other scales are often difficult to understand, which could consequently lead to an overestimation of the pain intensity. In dental or OMFS research, the use of the VAS is more common because it is more reliable, valid, sensitive, and appropriate. However, some researchers use NRS to evaluate OMFS pain in adults because this scale is easier to use than VAS and yields relatively similar pain scores. This review only assessed pain scales used for post-operative OMFS or dental pain.

      • KCI등재

        Flow-Cytometric Analysis of HNA-2 Expression and Phenotypes Among Thai Blood Donors

        Oytip Nathalang,Kanokpol Siriphanthong,Sawang Petvises,Nichapa Jeumjanya 대한진단검사의학회 2018 Annals of Laboratory Medicine Vol.38 No.4

        Background: Antibodies specific to human neutrophil antigen (HNA), especially HNA-2, are implicated in various conditions, including neonatal alloimmune neutropenia, febrile non-hemolytic transfusion reactions, and transfusion-related acute lung injury. The distribution of the HNA-2 phenotype frequencies in the Thai population remains unknown. This study aimed to investigate HNA-2 phenotype frequencies in Thai blood donors and to compare the relationships of sex and age with HNA-2 expression. Methods: EDTA blood samples were collected from 220 unrelated healthy Thai blood donors, including 150 males and 70 females, with ages ranging from 20 to 57 years. Polymorphonuclear cells were isolated and stained with monoclonal antibodies clone MEM- 166 and clone 2D1, which are specific to human CD177 (HNA-2) and CD45, respectively. HNA-2 expression according to sex and age was analyzed by flow cytometry. Results: Among the 220 donors, HNA-2-positive and HNA-2-null-phenotype frequencies were 0.995 and 0.005, respectively. Mean antigen expression was significantly higher in women (71.01±15.46%) than in men (64.59±18.85%; P <0.05). No significant differences in HNA-2 expression were found between different age groups. HNA-2 phenotype frequencies were similar to those in Asian, African, American, and Brazilian populations, but were significantly different from those in eastern Japanese, Korean, and French populations (P <0.001). Conclusions: This is the first report of HNA-2 phenotype frequencies in a Thai population, and the data will be helpful in predicting the risk of HNA-2 alloimmunization and in recruiting granulocyte panel donors.

      • KCI등재

        High levels of soluble herpes virus entry mediator in sera of patients with allergic and autoimmune diseases

        HyoWonJung,SuJinLa,JiYoungKim,SukKyeungHeo,JuYangKim,SaWang,KackKyunKim,KiManLee,HongRaeCho,HyeonWooLee,ByungsukKwon,ByungSamKim,ByoungSeKwon 생화학분자생물학회 2003 Experimental and molecular medicine Vol.35 No.6

        Herpes virus entry mediator (HVEM) is a newly discovered member of the tumor necrosis factor herpes simplex virus entry, in T cell activation and in tumor imunity. We generated mAb against HVEM and detected soluble HVEM (SHVEM) in the sera of patients with various autoimune diseases. HVEM was constitutively expresed on CD4+ and CD8+T cels, CD19+B cels, CD14+monocytes, neutrophils and dendritic cels. In thre-way MLR, mAb 122 and 139 were agonists and mAb 108 had blocking activity. An ELISA was developed to detect sHVEM in patient sera. sHVEM levels were elevated dermatitis and rheumatoid arthritis. The mAbs dis-cussed here may be useful for studies of the role of HVEM in imune responses. Detection of soluble HVEM might have diagnostic and prognostic value in certain imunological disorders.

      • KCI등재

        Trans-free Margarine Fat Produced Using Enzymatic Interesterification of Rice Bran Oil and Hard Palm Stearin

        Pimwalan Ornla-ied,Sopark Sonwai,Sawang Lertthirasuntorn 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.3

        Trans-free interesterified fats were prepared from blends of hard palm stearin (hPS) and rice bran oil (RBO) at 20:80, 30:70, 40:60, 50:50, 60:40, 70:30, and 80:20 weight % using immobilized Mucor miehei lipase at 60oC for 6 h with a mixing speed of 300 rpm. Physical properties and crystallization and melting behaviors of interesterified blends were investigated and compared with commercial margarine fats. Lipase-catalyzed interesterification modified triacylglycerol compositions and physical and thermal properties of hPS:RBO blends. Slip melting point and solid fat contents (SFC) of all blends decreased after interesterification. Small, mostly β' form, needle-shaped crystals, desirable for margarines were observed in interesterified fats. Interesterified blend 40:60 exhibited an SFC profile and crystallization and melting characteristics most similar to commercial margarine fats and also had small needle-like β' crystals. Interesterified blend 40:60 was suitable for use as a transfree margarine fat.

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