Resistance to sliding in orthodontics: misconception or method error? A systematic review and a proposal of a test protocol

Fabio Savoldi,Aggeliki Papoutsi,Simona Dianiskova,Domenico Dalessandri,Stefano Bonetti,James K. H. Tsoi,Jukka P. Matinlinna,Corrado Paganelli 대한치과교정학회 2018 대한치과교정학회지 Vol.48 No.4

Resistance to sliding (RS) between the bracket, wire, and ligature has been largely debated in orthodontics. Despite the extensive number of published studies, the lack of discussion of the methods used has led to little understanding of this phenomenon. The aim of this study was to discuss variables affecting RS in orthodontics and to suggest an operative protocol. The search included PubMed©, Medline©, and the Cochrane Library©. References of full-text articles were manually analyzed. English-language articles published between January 2007 and January 2017 that performed an in vitro analysis of RS between the bracket, wire, and ligature were included. Study methods were analyzed based on the study design, description of materials, and experimental setup, and a protocol to standardize the testing methods was proposed. From 404 articles identified from the database search and 242 records selected from published references, 101 were eligible for the qualitative analysis, and six for the quantitative synthesis. One or more experimental parameters were incompatible and a meta-analysis was not performed. Major factors regarding the study design, materials, and experimental setup were not clearly described by most studies. The normal force, that is the force perpendicular to the sliding of the wire and one of the most relevant variable in RS, was not considered by most studies. Different variables were introduced, often acting as confounding factors. A protocol was suggested to standardize testing procedures and enhance the understanding of in vitro findings.[Korean J Orthod 2018;48(4):268-280]

Clinical effects of different prescriptions on the inclination of maxillary and mandibular incisors by using passive self-ligating brackets

Fabio Savoldi,Linda Sangalli,Luis T. Huanca Ghislanzoni,Domenico Dalessandri,Min Gu,Gualtiero Mandelli,Corrado Paganelli 대한치과교정학회 2022 대한치과교정학회지 Vol.52 No.6

Objective: Controlling the incisal inclination is fundamental in orthodontics. However, the relationship between the inclination prescription and its clinical outcome is not obvious, and the incisal inclination changes generated by different bracket prescriptions were investigated. Methods: Twenty-eight non-extraction dental Class II patients (15 females, 13 males; mean age = 12.9) were retrospectively analyzed. Patients were treated using passive self-ligating fixed appliances with three inclination prescriptions for maxillary incisors (high, standard, low), and two for mandibular incisors (standard, low). Clinical outcomes were compared among different prescriptions, and regression analysis was used to explain the effects of bracket prescriptions and to understand the prescription selection criteria (α = 0.05). Results: For maxillary central incisors, low and high prescriptions were related to linguoversion (p = 0.046) and labioversion (p = 0.005), respectively, while standard prescription maintained the initial dental inclination. Maxillary lateral incisors did not show significant changes. For mandibular incisors, low prescription led to linguoversion (p = 0.005 for central incisors, p = 0.010 for lateral incisors), while standard prescription led to labioversion (p = 0.045 for central incisors, p = 0.005 for lateral incisors). The factors affecting inclination changes were the imposed change and selected prescription, while prescription selection was influenced by the initial dental inclination and initial intercanine distance. Conclusions: The direction of correction of incisal inclination can be controlled by choosing a certain prescription, but the final inclination may show limited consistency with it. The amount of imposed inclination change was the most relevant predictor of the clinical outcome.

Remote digital monitoring during the retention phase of orthodontic treatment: A prospective feasibility study

Sangalli Linda,Savoldi Fabio,Dalessandri Domenico,Visconti Luca,Massetti Francesca,Bonetti Stefano 대한치과교정학회 2022 대한치과교정학회지 Vol.52 No.2

Objective: To evaluate if a remote digital monitoring system added at the end of orthodontic treatment could positively influence the retention phase by reducing the occurrence of misfit of removable appliances, number of emergency appointments (EA), and orthodontic relapse. Methods: Twenty-seven patients who completed active orthodontic treatment were divided into the study and control groups. In addition to the standard chairside follow-up appointments at month 1 (T1), month 3 (T2), month 6 (T3), the study group patients were monitored using Dental Monitoring® with monthly intra-oral scans. Occurrence of misfit of removable retainers, number of EAs, and intercanine width change were recorded for both groups. Differences in EAs and retainer fit were assessed using the chi-square test. Intra-group and inter-group differences in the intercanine width were assessed with Friedman test and Mann–Whitney U test, respectively (α = 0.05). Results: The study group showed a significantly lower occurrence of misfit of removable retainers (p = 0.027) compared to the control group. No significant inter- and intra-group difference was found in the EAs and intercanine width change at each time-point. Conclusions: Integrating remote monitoring systems, such as Dental Monitoring®, to the retention phase of the orthodontic treatment may lower the occurrence of misfit of removable retainers. However, a small sample size and a short observation period limit the strength of this evidence. These preliminary results tentatively suggest that remote monitoring technologies may be beneficial, especially during the COVID-19 pandemic, when the regularity of in-office visits might be disrupted.

Data Extraction from Damage Compressed File for Computer Forensic Purposes

Bora Park,Antonio Savoldi,Paolo Gubian,Jungheum Park,Seok Hee Lee,Sangjin Lee 보안공학연구지원센터 2008 International Journal of Hybrid Information Techno Vol.1 No.4

Nowadays compressed files are very widespread and can be considered, without any doubt, with regard to the Digital Forensic realm, an important and precious source of probatory data. This is especially true when in a digital investigation the examiner has to deal with corrupted compressed files, which have been gathered in the collection phase of the investigative process. Therefore, in the computer forensic field, data recovery technologies are very important for acquiring useful pieces of data which can become, in a court of low, digital evidence. This kind of technology is used not only by law enforcement, but also by the multitude of users in their daily activities, which justify the relevant presence of tools in the software market which are devoted to rescue data from damaged compressed files. However, state-of-the-art data recovery tools have many limitations with regard to the capability of recovering the original data, especially in the case of damaged compressed files. So far, such recovery tools have been based on a schema which controls the signature/header of the file and, thus, provides the offset to the raw compressed data block. As a result, they cannot recover the compressed files if the first part of the raw compressed data block, which pertains to the header, is damaged or the signature/header block is corrupted. Therefore, in order to deal with this issue, we have developed a new tool capable of rescuing damaged compressed files, according to the DEFLATE compression scheme, even though the header block is missing or corrupted. This represents a new interesting opportunity for the digital forensic discipline.

Two-fluid modelling for poly-disperse bubbly flows in vertical pipes: Analysis of the impact of geometrical parameters and heat transfer

Allio Andrea,Buffo Antonio,Marchisio Daniele,Savoldi Laura 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.3

The bubbly flow of air or steam in subcooled water are investigated here in several test cases, characterized by different pipe sizes, bubble dimensions and flow rates, by means of CFD using a Eulerian- Eulerian approach. The performance of models that differ for the turbulence closure in the continuous phase, as well as for the description of the lift force on the dispersed phase, are compared in detail. When air is considered, the space of the experimental parameters leading to a reasonable performance for the selected models are identified and discussed, while the issues left in the modelling of the concurrent condensation are highlighted for the cases where steam is used.

Proposed parameters of optimal central incisor positioning in orthodontic treatment planning: A systematic review

Linda Sangalli,Domenico Dalessandri,Stefano Bonetti,Gualtiero Mandelli,Luca Visconti,Fabio Savoldi 대한치과교정학회 2022 대한치과교정학회지 Vol.52 No.1

Objective: Planning of incisal position is crucial for optimal orthodontic treatment outcomes due to its consequences on facial esthetics and occlusion. A systematic summary of the proposed parameters is presented. Methods: Studies on Google Scholar©, PubMed©, and Cochrane Library, providing quantitative information on optimal central incisor position were included. Results: Upper incisors supero-inferior position (4–5 mm to upper lip, 67–73 mm to axial plane through pupils), antero-posterior position (3–4 mm to Nasion-A, 3–6 mm to A-Pogonion, 9–12 mm to true vertical line, 5 mm to A-projection, 9–10 mm to coronal plane through pupils), bucco-lingual angulation (4–7° to occlusal plane perpendicular on models, 20–22° to Nasion-A, 57–58° to upper occlusal plane, 16–20° to coronal plane through pupils, 108–110° to anterior-posterior nasal spine), mesio-distal angulation (5° to occlusal plane perpendicular on models). Lower incisors supero-inferior position (41–48 mm to soft-tissue mandibular plane), antero-posterior position (3–4 mm to Nasion-B, 1–3 mm to A-Pogonion, 12–15 mm to true vertical line, 6–8 mm to coronal plane through pupils), bucco-lingual angulation (1-4° to occlusal plane perpendicular on models, 87–94° to mandibular plane, 68° to Frankfurt plane, 22–25° to Nasion-B, 105° to occlusal plane, 64° to lower occlusal plane, 21° to A-Pogonion), mesiodistal angulation (2° to occlusal plane perpendicular on models). Conclusions: Although these findings can provide clinical guideline, they derive from heterogeneous studies in terms of subject characteristics and reference methods. Therefore, the optimal incisal position remains debatable.

The conserved and divergent roles of carbonic anhydrases in the filamentous fungi <i>Aspergillus fumigatus</i> and <i>Aspergillus nidulans</i>

Han, Kap-Hoon,Chun, Yoon-Hee,de Castro Pimentel Figueiredo, Bá,rbara,Soriani, Frederico Marianetti,Savoldi, Marcela,Almeida, Agostinho,Rodrigues, Fernando,Cairns, Charlie Timothy,Bignell, Elaine Blackwell Publishing Ltd 2010 Molecular microbiology Vol.75 No.6

<P>Summary</P><P>Carbon dioxide (CO<SUB>2</SUB>) and its hydration product bicarbonate (HCO<SUB>3</SUB><SUP>-</SUP>) are essential molecules in various physiological processes of all living organisms. The reversible interconversion between CO<SUB>2</SUB> and HCO<SUB>3</SUB><SUP>-</SUP> is in equilibrium. This reaction is slow without catalyst, but can be rapidly facilitated by Zn<SUP>2+</SUP>-metalloenzymes named carbonic anhydrases (CAs). To gain an insight into the function of multiple clades of fungal CA, we chose to investigate the filamentous fungi <I>Aspergillus fumigatus</I> and <I>A. nidulans</I>. We identified four and two CAs in <I>A. fumigatus</I> and <I>A. nidulans</I>, respectively, named <I>cafA-D</I> and <I>canA-B</I>. The <I>cafA</I> and <I>cafB</I> genes are constitutively, strongly expressed whereas <I>cafC</I> and <I>cafD</I> genes are weakly expressed but CO<SUB>2</SUB>-inducible. Heterologous expression of the <I>A. fumigatus cafB</I>, and <I>A. nidulans canA</I> and <I>canB</I> genes completely rescued the high CO<SUB>2</SUB>-requiring phenotype of a <I>Saccharomyces cerevisiae</I>&Dgr;<I>nce103</I> mutant. Only the &Dgr;<I>cafA</I>&Dgr;<I>cafB</I> and &Dgr;<I>canB</I> deletion mutants were unable to grow at 0.033% CO<SUB>2</SUB>, of which growth defects can be restored by high CO<SUB>2</SUB>. Defects in the CAs can affect <I>Aspergilli</I> conidiation. Furthermore, <I>A. fumigatus</I>&Dgr;<I>cafA</I>, &Dgr;<I>cafB</I>, &Dgr;<I>cafC</I>, &Dgr;<I>cafD</I> and &Dgr;<I>cafA</I>&Dgr;<I>cafB</I> mutant strains are fully virulent in a low-dose murine infection.</P>