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      • KCI등재

        Computed Diffusion-Weighted Imaging in Prostate Cancer: Basics, Advantages, Cautions, and Future Prospects

        Yoshiko Ramirez Ueno,Tsutomu Tamada,Satoru Takahashi,Utaru Tanaka,Keitaro Sofue,Tomonori Kanda,Munenobu Nogami,Yoshiharu Ohno,Nobuyuki Hinata,Masato Fujisawa,Takamichi Murakami 대한영상의학회 2018 Korean Journal of Radiology Vol.19 No.5

        Computed diffusion-weighted MRI is a recently proposed post-processing technique that produces b-value images from diffusion-weighted imaging (DWI), acquired using at least two different b-values. This article presents an argument for computed DWI for prostate cancer by viewing four aspects of DWI: fundamentals, image quality and diagnostic performance, computing procedures, and future uses.

      • KCI등재

        Prompt gamma detection for range verification in proton therapy

        Shunsuke Kurosawa,Hidetoshi Kubo,Kazuki Ueno,Shigeto Kabuki,Satoru Iwaki,Michiaki Takahashi,Kojiro Taniue,Naoki Higashi,Kentaro Miuchi,Toru Tanimori,김도균,김종원 한국물리학회 2012 Current Applied Physics Vol.12 No.2

        It is an on-going challenge to verify the proton range in situ during proton therapy. Since the protons stop in target tissue, measurement of gamma-rays emitted either promptly from nuclear de-excitation or in pair from positron annihilation is the feasible method to monitor the proton range in-vivo. Using the technique of gamma collimation, we empirically demonstrated that the proton range and prompt gamma distribution are well correlated in the therapy energy range, and that measuring prompt gammas is a viable method for the clinical application. However, this collimation technique appears not to be applicable to passively scattered proton beams. The device chosen for gamma imaging in 2D is an electron tracking Compton camera, which images single-emission photons employing a gas chamber to induce Compton scattering. Images of prompt gammas were attained at the proton beam energy of 140 MeV. Measurements showed that gamma image in the energy range of 800e2000 keV provides a better match with the proton range compared to the image by lower energy gammas.

      • Gelation of Solvate Ionic Liquid by Self-Assembly of Block Copolymer and Characterization as Polymer Electrolyte

        Kitazawa, Yuzo,Iwata, Kaori,Imaizumi, Satoru,Ahn, Hyungmin,Kim, Sung Yeon,Ueno, Kazuhide,Park, Moon Jeong,Watanabe, Masayoshi American Chemical Society 2014 Macromolecules Vol.47 No.17

        <P>We report a new class of polymer electrolytes that exhibit high Li<SUP>+</SUP>-ionic conductivity and thermal stability up to 200 °C. The polymer electrolyte consists of a solvate ionic liquid ([Li(G4)][TFSA]), comprising an equimolar mixture of lithium bis(trifluoromethanesulfonyl)amide (Li[TFSA]) and tetraglyme (G4), and a well-defined ABA-triblock copolymer, polystyrene-<I>b</I>-poly(methyl methacrylate)-<I>b</I>-polystyrene (PSt-<I>b</I>-PMMA-<I>b</I>-PSt, SMS). The electrolyte is formed by the self-assembly of SMS, where the solvatophobic PSt segments serves as physical cross-linking points, and the solvatophilic PMMA segment with preferentially dissolved [Li(G4)][TFSA] forms ion-conduction paths. In the electrolyte, the preservation of the complex cation [Li(G4)]<SUP>+</SUP> in the PMMA phase was demonstrated by pulsed-field gradient spin–echo (PGSE) NMR, Raman spectra, and thermogravimetric analysis. Because of the preservation of [Li(G4)]<SUP>+</SUP>, which hinders the direct interaction of Li<SUP>+</SUP> with the polymer segment and the coupling of the ionic transport from the segmental motion, the room temperature ionic conductivity of the electrolyte reached an appreciable level (10<SUP>–4</SUP>–10<SUP>–3</SUP> S cm<SUP>–1</SUP>).</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/mamobx/2014/mamobx.2014.47.issue-17/ma501296m/production/images/medium/ma-2014-01296m_0011.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ma501296m'>ACS Electronic Supporting Info</A></P>

      • KCI등재

        Dual-Energy Subtraction Imaging for Diagnosing Vocal Cord Paralysis with Flat Panel Detector Radiography

        Haruhiko Machida,Keiko Yoda,Yasuko Arai,Suguru Nishida,Ai Masukawa,Masayasu Asanuma,Toshiyuki Yuhara,Satoru Morita,Kazufumi Suzuki,Eiko Ueno,John M Sabol 대한영상의학회 2010 Korean Journal of Radiology Vol.11 No.3

        Objective: To investigate the clinical feasibility of dual energy subtraction (DES) imaging to improve the delineation of the vocal cord and diagnostic accuracy of vocal cord paralysis as compared with the anterior-posterior view of flat panel detector (FPD) neck radiography. Materials and Methods: For 122 consecutive patients who underwent both a flexible laryngoscopy and conventional/DES FPD radiography, three blinded readers retrospectively graded the radiographs during phonation and inspiration on a scale of 1 (poor) to 5 (excellent) for the delineation of the vocal cord, and in consensus, reviewed the diagnostic accuracy of vocal cord paralysis employing the laryngoscopy as the reference. We compared vocal cord delineation scores and accuracy of vocal cord paralysis diagnosis by both conventional and DES techniques using κstatistics and assessing the area under the receiver operating characteristic curve (AUC). Results: Vocal cord delineation scores by DES (mean, 4.2 ± 0.4) were significantly higher than those by conventional imaging (mean, 3.3 ± 0.5) (p < 0.0001). Sensitivity for diagnosing vocal cord paralysis by the conventional technique was 25%, whereas the specificity was 94%. Sensitivity by DES was 75%, whereas the specificity was 96%. The diagnostic accuracy by DES was significantly superior (κ= 0.60, AUC = 0.909) to that by conventional technique (κ= 0.18, AUC = 0.852) (p = 0.038). Conclusion: Dual energy subtraction is a superior method compared to the conventional FPD radiography for delineating the vocal cord and accurately diagnosing vocal cord paralysis. Objective: To investigate the clinical feasibility of dual energy subtraction (DES) imaging to improve the delineation of the vocal cord and diagnostic accuracy of vocal cord paralysis as compared with the anterior-posterior view of flat panel detector (FPD) neck radiography. Materials and Methods: For 122 consecutive patients who underwent both a flexible laryngoscopy and conventional/DES FPD radiography, three blinded readers retrospectively graded the radiographs during phonation and inspiration on a scale of 1 (poor) to 5 (excellent) for the delineation of the vocal cord, and in consensus, reviewed the diagnostic accuracy of vocal cord paralysis employing the laryngoscopy as the reference. We compared vocal cord delineation scores and accuracy of vocal cord paralysis diagnosis by both conventional and DES techniques using κstatistics and assessing the area under the receiver operating characteristic curve (AUC). Results: Vocal cord delineation scores by DES (mean, 4.2 ± 0.4) were significantly higher than those by conventional imaging (mean, 3.3 ± 0.5) (p < 0.0001). Sensitivity for diagnosing vocal cord paralysis by the conventional technique was 25%, whereas the specificity was 94%. Sensitivity by DES was 75%, whereas the specificity was 96%. The diagnostic accuracy by DES was significantly superior (κ= 0.60, AUC = 0.909) to that by conventional technique (κ= 0.18, AUC = 0.852) (p = 0.038). Conclusion: Dual energy subtraction is a superior method compared to the conventional FPD radiography for delineating the vocal cord and accurately diagnosing vocal cord paralysis.

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