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Sangsoo Han(한상수),Hee-Jun Shin(신희준) 한국산학기술학회 2018 한국산학기술학회논문지 Vol.19 No.11
본 메탄올은 공업용 용매로 흔히 사용되는 무색의 휘발성, 유독성 액체이다. 메탄올 중독에 의해서 시각 장애는 흔히 나타나는 증상 및 후유증의 하나지만, 흡입으로 인한 중독에서는 잘 나타나지 않는 것으로 알려져 있다. 그렇기 때문에 메탄올을 흡인한 이후에 시력저하가 생긴 증례는 잘 발표되어 있지 않다. 우리는 산업장에서 호흡기를 통해서 메탄올이 흡입된 이후에 시력손실이 발생한 케이스를 보고하고자 한다. 한국의 한 휴대폰 공장에서 일하던 28세 여자환자가 의식저하로 응급실로 내원하였다. 그녀는 이틀 전부터 시야가 흐릿하게 보였지만 대수롭지 않게 여겨 따로 병원을 찾아가지 않았고, 의식저하가 발생하여서야 병원에 오게 되었다. 내원시 환자는 글래스고혼수척도 9점의 의식저하를 보였으며, 혈액 검사 결과 심한 대사성 산증을 보이고 있었다. 중환자실에 입원하여 응급 투석을 비롯하여 메탄올 중독에 대한 치료를 시행하였다. 치료 후 의식이 회복되어 퇴원할 수 있었으나, 6개월 후까지 재활치료를 받고 있으며, 영구적으로 시력저하가 남았다. 흡입을 통해서도 메탄올 중독이 발생 할 수 있으며, 이는 초기에 알아차리기가 쉽지 않다. 하지만 메탄올 중독의 치료는 시간과의 싸움이 며, 초기에 빠르게 치료해야 예후가 좋다. 그러므로 흡입에 의한 중독 가능성을 항상 염두에 두어야 하며, 의심시에는 빠르게 치료를 해야만 한다. Methanol is a clear, colorless, volatile, and poisonous liquid that is commonly used as an industrial solvent. Visual impairment is a common symptom of methanol poisoning; however, visual impairment rarely occurs after exposure through inhalation. Therefore, visual loss after methanol intoxication via respiration has rarely been reported. We report a case of visual damage associated with methanol poisoning via respiratory exposure in an industrial setting. In this case in South Korea, a 28-year-old woman who worked at a cell phone factory was admitted to the emergency department with mental changes. She had blurred vision that began two days prior, but she did not come to the hospital until she experienced mental changes. She ranked 9 on the Glasgow Coma Scale and presented with severe metabolic acidosis. So, she was admitted to intensive care, and continuous renal replacement therapy was performed. Finally, she was discharged after recovery of her mental state, but had to undergo rehabilitation for six months. Also, her visual impairment was permanent. Methanol intoxication can occur through inhalation, which is difficult to detect initially. However, treatment of methanol poisoning is time-critical. Therefore, doctors should always keep in mind that methanol intoxication may occur via respiration. If in doubt, treatment should be given as soon as possible.
Development of bismuth-functionalized graphene oxide to remove radioactive iodine
Han, Sangsoo,Um, Wooyong,Kim, Won-Seok The Royal Society of Chemistry 2019 Dalton Transactions Vol.48 No.2
<P>Bismuth-functionalized graphene oxide (Bi-GO) was successfully synthesized and showed both high iodide and iodate removal efficiencies from radioactive wastewater. Batch experiments for kinetic and selectivity tests were performed, respectively. Additional SEM, XRD, FT-IR, and XPS analyses were performed for characterization of a sorbent and bismuth on the GO surface and this confirmed that bismuth on the GO surface reacted with iodine species by surface complexation (or precipitation). Dominant surface species are BiOI and Bi(IO3)3 for iodide and iodate removal, respectively. After the selectivity test using a KCl background solution with varying concentrations, Bi-GO still showed higher removal efficiencies (≥95%) for both iodide and iodate than the commercial silver-exchanged zeolite (≥95% for iodide and ≤25% for iodate). Our study suggests the potential application of Bi on graphene-based materials for selective removal of both iodide and iodate from radioactive wastewater.</P>
( Sangsoo Han ),( Miyoung Choi ),( Bora Lee ),( Hye-won Lee ),( Seong Hee Kang ),( Yuri Cho ),( Sang Bong Ahn ),( Do Seon Song ),( Dae Won Jun ),( Jieun Lee ),( Jeong-ju Yoo ) 대한소화기기능성질환·운동학회 2022 Gut and Liver Vol.16 No.6
Background/Aims: Several noninvasive scoring systems have been developed to determine the risk of advanced fibrosis in nonalcoholic fatty liver disease (NAFLD). We examined the diagnostic accuracy of the fibrosis-4 (FIB-4) score and NAFLD fibrosis score (NFS) in patients with biopsy-proven NAFLD. Methods: For this meta-analysis, various databases including PubMed (MEDLINE), EMBASE, OVID Medline and the Cochrane Library were systematically searched. After the acquired abstracts were reviewed by two investigators, manuscripts were chosen for a full-text examination. Results: Thirty-six studies evaluating biopsy-proven NAFLD were selected for meta-analysis. A total of 14,992 patients were analyzed. The lower cutoff sensitivity of the FIB-4 score predicting histological fibrosis stage 3 or more (≥F3) was 69%, with specificity of 64%, positive likelihood ratio (LR+) of 1.96, and negative likelihood ratio (LR-) of 0.47. The low baseline sensitivity of the NFS score predicting ≥F3 was 70%, with a specificity of 61%, LR+ of 1.83, and LR- of 0.48. The area under the receiver operating characteristic curve (AUC) values of the FIB-4 score predicting ≥F3 and ≥F2 were 76% and 68%, respectively. The AUC values of the NFS score predicting ≥F3 and ≥F2 were 74% and 60%, respectively. Conclusions: The FIB-4 or NFS test can be used to predict the degree of liver fibrosis in NAFLD, and the diagnostic accuracy resulted as relatively high in fibrosis stages of F3 or higher. (Gut Liver 2022;16:952-963)
Emergent use of a King laryngeal tube for traumatic intraoral bleeding: two case reports
Kim Han Bit,최성우,Min Seung June,Han Sangsoo,강보라,Kim Giwoon 대한응급의학회 2022 Clinical and Experimental Emergency Medicine Vol.9 No.3
Maxillofacial trauma occasionally presents a serious challenge for physicians, and an orofacial injury can be considered life-threatening. It is difficult to control the bleeding and prevent airway obstruction simultaneously with conventional treatment. Herein, we share two cases in which we managed massive orofacial bleeding using a King laryngeal tube, a supraglottic airway device equipped with an inflatable balloon. Both patients had uncontrolled orofacial bleeding. In one of the patients, endotracheal intubation was possible; however, bleeding continued, and vital signs became unstable. The second patient had failed endotracheal intubation due to uncontrolled bleeding. We deployed the King laryngeal tube in both patients and achieved bleeding control and airway maintenance. Both patients were discharged without complications after 3 to 4 weeks. The King laryngeal tube method can be considered a useful management option for addressing massive orofacial bleeding that is uncontrollable with conventional treatment.
한상수(Sangsoo Han),정선태(Suntae Jung),이진형(Jinhyung Lee),김보경(Bokyoung Kim),김경민(Kyungmin Kim) 한국지반환경공학회 2016 한국지반환경공학회논문집 Vol.17 No.3
쇄석말뚝공법은 비교적 강성이 크고 압축성이 작은 쇄석을 연약한 점성토 지반 및 느슨한 사질토 지반에 치환 후 다져 시공함으로써 연약한 지반의 지지력 증가와 침하량 감소, 압밀배수에 의한 지반개량 효과에 더불어 사질토 지반에서는 지진 발생시 액상화 방지에 효과적인 공법이다. 쇄석말뚝공법은 여러 토목분야에서 활용되고 국제적으로 상당히 많은 시공실적을 보이고 있으나, 아직까지 정형화된 침하량 산정방법은 없다. 따라서 본 연구에서는 쇄석말뚝공법의 합리적인 침하량을 예측하기 위하여 기존에 제안되어 사용되고 있는 침하량 이론식들을 비교・분석하여 적용성을 평가하였다. 그 결과 Hook’s law 식이 수치해석과 가장 근접하는 것으로 확인되었다. Stone column is the method that replace soft ground such as weak clay and loose sand with gravel or crushed stone which has relatively high stiffness and low compressive. Stone column increases bearing capacity of the soft ground, reduces settlement, produces ground improvement effect by consolidation drain, and is effective to prevent soil liquefaction in sandy ground during an earthquake. Stone column has been used in many civil works, and has recorded quite a lot of construction achievement internationally, but there is no standardized settlement calculation method yet. Therefore, in this study, the applicability of the existing theoretical equations were evaluated through comparison and analysis to predict a reasonable settlement of the Stone column. Consequently, Hook’s law formula was verified to be the most close to numerical analysis.