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        Prospective experimental studies of some herbs used in urinary disorders in Unani medicine

        Anjan Adhikari,Sangita Bhattacharya,Sankhadip Bose,Moumita Ray,Rania Indu,Sabyasachi Banerjee 경희대학교 융합한의과학연구소 2023 Oriental Pharmacy and Experimental Medicine Vol.23 No.3

        Diseases of the kidney and urinary tract including urolithiasis became a major cause of global illness and death. There are approximately 7.85 million people suffering from chronic renal failure in India. Further, urolithiasis is also a common global phenomenon of renal disorders. Unani Medicine (UM) is a famous kind of conventional medicine practised throughout South Asia that relies on the ancient conventional medicinal systems of India, Egypt, China, Iraq, Syria, and Persia. Berberis vulgaris (BV), Physalis alkekengi (PA) and Boswellia serrata (BS) are very common drugs against urinary disorders in Unani medicine. But, to establish their role to treat in urinary disorders are still obscure. HPTLC fingerprints confirmed the presence of signature compounds according to pharmacopeia. Polyphenolic acids and flavonoids in the test drugs have been quantified by HPLC. BS showed maximum inhibitory action on DPPH (2,2-diphenyl-1-picrylhydrazyl) radicals, nitric oxide and superoxide scavenging than other two test drugs, while, PA have highest hydrogen peroxide scavenging action. In diuretic activity, maximum urination occurred in BS group than other two test drugs BV and PA. The highest excretion of sodium–potassium ratio was noted in PA groups followed by BS and BV. BV showed maximum efficacy in crystal formation in test tubes followed by BS and PA.

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