양주 노고산(老姑山) 독재동(篤才洞)의 장소성과 역사문화경관 해석

노재현 ( Jae Hyun Rho ),김화옥 ( Hwa Ok Kim ),이정한 ( Jung Han Lee ),박주성 ( Joo Sung Park ) 한국전통조경학회 2015 한국전통조경학회지 Vol.33 No.1

본 연구는 경기도 양주시 장흥면 삼하리 독재동 바위글씨와 노고산의 장소성에 주목하여, 이곳의 경관 및 장소특질을 고찰하고 바위글씨에 담긴 경관의미를 추론함으로써 노고산과 독재동 계곡의 역사문화경관적 함의를 밝히고자 한 것으로 연구 결과는 다음과 같다. 삼각산은 조선왕조 6백년 도읍지의 주산(主山)이며 오악(五嶽)을 이루는 중앙의 성산(聖山)으로, 노고산은 삼봉산(三峰山)즉 삼각산의 우람한 세봉우리를 향배하는 의미공간으로서 그 장소성이 획득된다. 더불어 노고산은 조선의 정기를 상징하는 삼각산을 가장 완벽하게 조망할 수 있는 ‘망삼각산(望三角山)’의 절대 시점장이다. 독재동 계곡에 산포(散布)된 다수의 바위글씨는 미수 허목의『고양산수기』의 내용을 현현(顯現)하기 위한 행위이자 경물로 재생산된 산물이다. 그리고 추사 필적의 몽재(夢齋)는 중의적(衆意的) 표현이 읽혀지는 바위글씨로, 먼저 글자 그대로의 뜻인 ‘꿈꾸는 집’ 이지만 내면적 의미는 “한낮 몽상(夢想)도 바탕을 깊이 헤아려 보면 정당성이 확보된다.”는 의미로 ‘몽재거사’로 알려진 성재(性齋) 허전(許傳)의 『몽재집(夢齋集)』서(序)의 내용으로 보아 성재의 독재동 거주와 관련된 징표로 추정된다. 또한 몽재라 쓴 바위 하단의 갑자(甲子)·경오(庚午)·무술(戊戌)·갑인(甲寅) 등의 간지(干支)는 추사와의 교유관계가 있는 1804년 5월생 유생(儒生)의 사주팔자로 판단된다. 노고산과 독재동 계곡은 삼각산을 조망하는 장소일 뿐 아니라 송월재·성재 등 미수의 학통을 계승한 기호지역의 남인학자의 공통된 장구지소로써의 응집력을 보여준다. 또한 이곳에 각자(刻字)된 추사체와 미수체(전서체) 바위글씨는 우리나라 서예사의 큰 흐름을 함축적으로 보여준다는 측면에서도 매우 의미 깊은 역사문화경관이다. This study was focused on the placeness of Nogosan Dokjae-dong and rock inscription located in Jangheung-myeon, Yangju-si, Gyeonggi-do. The purpose was to reveal the implication of Nogosan and Dokjae-dong Valley in terms of Historic cultural landscape by considering the characteristics of the place and its landscape, and inferring the significance of the letters engraved on the rock. The result is as follows.10)Samgaksan is one of the five famous mountains in Korea. It is the sacred mountain that stands behind the capital city of the Joseon Dynasty that lasted for 600 years. On the other hand, the placeness of Nogosan is significant since it was the place where people used to bow low to the three great summits of Samgaksan. Furthermore, Nogosan was the perfect place to view Samgaksan that represented the Joseon spirit.Many letters were engraved on the rocks around Dokjae-dong Valley by Misu(眉수) Heo Mok(許穆) as part of his memories to describe his experience in the mountain and became a scenery. Chusa(秋史) Kim Jung-Hee(金正喜) also engraved letters of ``Mongjae`` on the rock that contains a double meaning. Literally, it means ‘a dreaming house’ However, it also implies that even just a daydream is significant in a way. These letters are presumed to be the signs that are related to Sung-Jae(性齋) Heo Jeon(許傳)’s experience in Dokjae-dong since the letters were part of his famous book title. Below these two letters, Chusa also engraved letters that describe the sexagenary cycle including the year of the rat, horse, dog, and tiger. They are regarded as the letters that describe the fate of Chusa’s friend, a scholar born in May 1804. Nogosan and Dongjae-dong Valley are very significant in terms of historic cultural landscape as a viewpoint to see Samgaksan; and a place that cherishes the traces of Misu and shows common values and cohesiveness of well-known scholars of the Joseon Dynasty including Song Wol-Jae(松月齋) and Sung-Jae as a of Gihonamin(畿湖南人). The engraved letters of Chusa and Misu also implicitly demonstrates the major trends of Korea’s calligraphy history.

One-pot Production of Adipic Acid from Syngas by Using Clostridium sp. JS66 and Escherichia coli

Sang Min KIM,Kweon Hwan JUNG,Youngsoon UM,Sun-Mi LEE,Gyeongtaek GONG,Ja Kyong KO,Sung Ok HAN,Jung Ho AHN 한국생물공학회 2023 한국생물공학회 학술대회 Vol.2023 No.10

The Mechanism of Anti-inflammation Effects of Propolis Components in Raw264.7 Macrophage Cell

Sung-Kuk Kim,Sang Mi Han,Se Gun Kim,Hyo Young Kim,Sik Ryu,Soon Ok Woo 한국양봉학회 2021 韓國養蜂學會誌 Vol.36 No.4

Overexpression of an Arabidopsis 관-glucosidase gene enhances drought resistance with dwarf phenotype in creeping bentgrass.

Han, Yun-Jeong,Cho, Kyu-Chang,Hwang, Ok-Jin,Choi, Yun-Sung,Shin, Ah-Young,Hwang, Inhwan,Kim, Jeong-Il Springer 2012 Plant cell reports Vol.31 No.9

<P>An Arabidopsis 관-glucosidase, AtBG1 is known to hydrolyze glucose-conjugated, biologically inactive abscisic acid (ABA) to produce active ABA, which increases the level of ABA in plants. Since an increase of ABA in plants confers tolerance against abiotic stress such as drought, we introduced the pCAMBIA3301 vector harboring the AtBG1 gene into creeping bentgrass through Agrobacterium-mediated transformation. After transformation, putative transgenic plants were selected using the BASTA resistance assay at a concentration of 0.8%. Genomic integration of the AtBG1 gene was confirmed by genomic PCR and Southern blot analysis, and gene expression was validated by Northern blot and Western blot analyses. Interestingly, the transgenic bentgrass plants overexpressing AtBG1 had a dwarf phenotype with reduced growth rates when compared to wild-type creeping bentgrass. In addition, the transgenic plants accumulated higher ABA levels and displayed enhanced drought tolerance. These results suggest that the expression of AtBG1 in plants induces the accumulation of higher ABA levels, which results in the formation of dwarf creeping bentgrass and enhances the survival in water-limiting environments.</P>

Analysis of the Physicochemical Properties of Beeswax of Apis mellifera Linnaeus and Apis cerana Fabricius

Sung-Kuk Kim,Sang Mi Han,Se Gun Kim,Hyo Young Kim,Hong Min Choi,Hye Jin Lee,Hyo Jung Moon,Soon Ok Woo 한국양봉학회 2022 韓國養蜂學會誌 Vol.37 No.4

To evaluate the physicochemical properties of beeswax produced by Apis mellifera Linnaeus (Am) and Apis cerana Fabricius (Ac), we collected and extracted pure beeswax from a bee hive. Detailed analysis of the physicochemical properties was then performed at the Korean Health Supplement Institute. We tested eight characteristics of the beeswax, including the levels of lead, arsenic, and mercury; melting point; acid value; saponification value; esterification value; and peroxide value of both Am and Ac beeswax. The levels of all heavy metals were below safety values, and melting points at 64.5°C were the same for the two beeswax samples. The esterification value of Ac beeswax (79.94) was higher than that of Am beeswax (73.73). However, the saponification, peroxide, and acid values of Am beeswax were higher than those of Ac beeswax. The saponification values for Ac and Am beeswax were 87.41 and 95.44, respectively. Notably, there was a significant difference in peroxide values and acid values between Ac and Am beeswax. The acid value and peroxide value of Am beeswax were more than 3-times and 45-times higher, respectively. Based on these results, beeswax can safely be used as a food additive.

Case Reports : A primo vessel-Like structure in a dog with inflammatory pseudotumor

( Sung Jin Cho ),( Sun Hwa Hong ),( Sang Jun Han ),( Ok Jin Kim ) 한국가축위생학회 2012 韓國家畜衛生學會誌 Vol.35 No.1

Inflammatory pseudotumor (IPT) is a term defining a mass characterized microscopically by a proliferation of bland mesenchymal spindle cells infiltrated by diffuse mixed inflammatory cells with a predominance of plasma cells and lymphocytes. Here, we show the primo vessel-like structure of the primo-vascular system (PVS) in a dog with IPT. A 6-years old male Mongrel dog was diagnosed with an abnormal mass (diameter 5.5 cm, weight 22 g) near left preputial area. The dog was submitted to the surgical detectomy of the mass. During the surgical operation, we observed primo vessel-like material. After fixations, the masses appeared macroscopically as lipoid-like, firm, white to grey masses, measuring 5×8 cm. Histologically, cellular infiltration into the muscular layers was frequently seen. The mesenchymal proliferation remained the main component of the mass and was composed of myofibroblastic- like spindle cells characterized by globular, irregular nuclei containing open chromatin and a prominent nucleolus. On the basis of the histopathologic lesions, the subcutaneous mass was diagnosed as IPT. Also, we detected a primo vessel-like structures in some areas of the IPT tissues. These were observed as novel thread-like structures and bundle of tubular structures. To our knowledge, this report is the first case of primo vessel-like structure in a dog with IPT.

Antimicrobial Activity of Propolis Extracts against Skin Flora

Sang Mi Han,In Pyo Hong,Soon Ok Woo,Hye Ri Jang,Se Gun Kim 한국양봉학회 2015 한국양봉학회 학술대회 자료집 Vol.2015 No.3

Ethanol extracts of <i>Aster yomena</i> (Kitam.) Honda inhibit adipogenesis through the activation of the AMPK signaling pathway in 3T3-L1 preadipocytes

Han, Min Ho,Jeong, Ji-Suk,Jeong, Jin-Woo,Choi, Sung Hyun,Kim, Sung Ok,Hong, Su Hyun,Park, Cheol,Kim, Byung Woo,Choi, Yung Hyun International Research and Cooperation Association 2017 Drug discoveries & therapeutics Vol.11 No.5

A study of the relationship between clinical phenotypes and plasma iduronate-2-sulfatase enzyme activities in Hunter syndrome patients

Ok Jeong Lee,Su-Jin Kim,박형두,이수연,Chi-Hwa Kim,Ah-Ra Ko,Yeon-Joo Yook,Su-Jin Lee,박성원,Se-Hwa Kim,Sung-Yoon Cho,Eun-Kyung Kwon,Sun Ju Han,진동규,Young Bae Sohn 대한소아청소년과학회 2012 Clinical and Experimental Pediatrics (CEP) Vol.55 No.3

Purpose: Mucopolysaccharidosis type II (MPS II or Hunter syndrome)is a rare lysosomal storage disorder caused by iduronate-2-sulfatase (IDS) deficiency. MPS II causes a wide phenotypic spectrum of symptoms ranging from mild to severe. IDS activity, which is measured in leukocyte pellets or fibroblasts, was reported to be related to clinical phenotype by Sukegawa-Hayasaka et al. Measurement of residual plasma IDS activity using a fluorometric assay is simpler than conventional measurements using skin fibroblasts or peripheral blood mononuclear cells. This is the first study to describe the relationship between plasma IDS activity and clinical phenotype of MPS II. Methods: We hypothesized that residual plasma IDS activity is related to clinical phenotype. We classified 43 Hunter syndrome patients as having attenuated or severe disease types based on clinical characteristics,especially intellectual and cognitive status. There were 27 patients with the severe type and 16 with the attenuated type. Plasma IDS activity was measured by a fluorometric enzyme assay using 4-methylumbelliferyl-α-iduronate 2-sulphate. Results: Plasma IDS activity in patients with the severe type was significantly lower than that in patients with the attenuated type (P=0.006). The optimal cut-off value of plasma IDS activity for distinguishing the severe type from the attenuated type was 0.63 nmol·4 hr-1·mL-1. This value had 88.2% sensitivity, 65.4% specificity, and an area under receiver-operator characteristics (ROC) curve of 0.768 (ROC curve analysis; P=0.003). Conclusion: These results show that the mild phenotype may be related to residual lysosomal enzyme activity.

Novel CIPK1-associated proteins in Arabidopsis contain an evolutionarily conserved C-terminal region that mediates nuclear localization.

Ok, Sung Han,Jeong, Hye Jin,Bae, Jung Myung,Shin, Jeong-Sheop,Luan, Sheng,Kim, Kyung-Nam American Society of Plant Physiologists 2005 PLANT PHYSIOLOGY - Vol.139 No.1

<P>Environmental stimuli, including light, pathogens, hormones, and abiotic stresses, elicit changes in the cytosolic Ca(2+) signatures of plant cells. However, little is known about the molecular mechanisms by which plants sense and transmit the specific cytoplasmic Ca(2+) signal into the nucleus, where gene regulation occurs to respond appropriately to the stress. In this study, we have identified two novel Arabidopsis (Arabidopsis thaliana) proteins specifically associated with Calcineurin B-Like-Interacting Protein Kinase1 (CIPK1), a member of Ser/Thr protein kinases that interact with the calcineurin B-like Ca(2+)-binding proteins. These two proteins contain a very similar C-terminal region (180 amino acids in length, 81% similarity), which is required and sufficient for both interaction with CIPK1 and translocation to the nucleus. Interestingly, the conserved C-terminal region was also found in many proteins from various eukaryotic organisms, including humans. However, none of them have been characterized so far. Taken together, these findings suggest that the two proteins containing the evolutionarily conserved C-terminal region (ECT1 and ECT2) may play a critical role in relaying the cytosolic Ca(2+) signals to the nucleus, thereby regulating gene expression.</P>