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salman,파잘 아카람,김준찬,송태권,김명호,이순일,Rizwan Ahmed Malik,Ali Hussain,김원정,성연수 한국물리학회 2019 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.75 No.10
In the present work, lead-free piezoelectric ceramics 0.65Bi1.05Fe1−xTixO3-0.35BaTi1−yNbyO3, where x = y = 0, 0.01, 0.015, 0.02, and 0.025, abbreviated as BFT-BTNb, were successfully synthesized by a solid-state reaction method and an air quenching method. The effects of B-Site donor modifications (Nb5+ and Ti4+) on the crystal structure, the morphology and the electrical properties of the 0.65BF-0.35BT ceramics were studied. X-ray diffraction patterns showed the formation of a pure perovskite structure, without any secondary phases. Scanning electron microscope (SEM) micrographs revealed that the average grain size of the BF-BT ceramics decreased with the addition of B-Site donors. Improvements in the ferroelectric properties (P-E loops) and the electric fieldinduced strain properties (S-E loops) were obtained at the optimum composition of the BFT-BTN ceramics. In addition, the dynamic piezoelectric coefficient (d ∗ 33) was enhanced from 265 pm/V for (BFT-BTNb-0) to 360 pm/V for (BFT-BTNb-1) with high working temperature, Tm = 320 ◦ C.
Salman Ali Khan,Tauseef Ahmed,Fazli Akram,Jihee Bae,Soo Yong Choi,Tran Thi Thanh,Mingyu Kim,송태권,성연수,Myong‑Ho Kim,Soonil Lee 한국세라믹학회 2020 한국세라믹학회지 Vol.57 No.3
In this study, 0.65Bi1.05FeO3–0.35BaTiO3 (BF-35BT) lead-free piezoelectric ceramics were prepared using a conventional solid-state method to determine the effects of sintering temperature on their microstructures and electrical properties. The average grain size increased with sintering temperature, but not significantly, and the relative density of the ceramics increased and then decreased at high sintering temperatures due to the volatilization of Bi2O3. At the optimal sintering temperature (1030 °C), BF-35BT ceramics showed minimum coercive field (Ec) with enhanced remanent polarization (Pr) and consequently resulted in a high converse piezoelectric coefficient (d* 33) value of 305 pm/V. The results indicate that the optimum sintering temperature, maximum relative density, and appropriate grain size, which are significantly related to the domain size and configuration, as well as the minimum concentration of associated charged defects, are critical factors that influence the piezoelectric performance of BF-35BT ceramics.
( Faiza Ahmed ),( Israr Khan ),( Nazma Hanif ),( Alaa Hamdan ),( Mohammad Ali Zaidi ),( Zeynep Yukselen ),( Umer Salman ),( Sakshi Mishra ),( Jack Michel ),( Muhammad Haris Khan ),( Andre Thompson ),( 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Background Pralsetinib and selpercatinib are anticancer drugs targeting RET fusions (oncogenic drivers) in non-small cell lung cancer (NSCLC). The US FDA approved both drugs in 2020 for the treatment of RET-fusion positive NSCLC. Methods We assessed the efficacy & safety of pralsetinib versus selpercatinib in RET fusion-positive NSCLC in two clinical trials: phase1/2 ARROW trial (n=354) and phase 1/2 LIBRETTO-001 trial (n=144). Results In patients who had previously received platinum-based therapy (n=105), Drilon et al., 2020 showed an overall response rate (ORR) of 64% (95% CI, 54-73) and a median duration of response (mDOR) of 17.5 months (95% CI, 12.0-NE) with selpercatinib in phase 1/2 LIBRETTO-001 trial. Furthermore, a complete response (CR) of 2%, partial response (PR) of 62%, stable disease (SD) of 29%, and median progression-free survival (mPFS) of 16.5 months ( 95% CI, 13.7 - NE) were reported. Treatment naive patients (n=39) demonstrated an ORR of 85% (95% CI, 70-94) and PR of 85%. The responses were determined by the independent review committee. Lee et al., 2019 (n=111) demonstrated a rapid lowering of RET circulating tumor DNA (ctDNA) in 81% of NSCLC patients with pralsetinib therapy. A phase 1/2 ARROW trial (n= 116) exhibited a median follow-up of 8.8 months in patients who received pralsetinib 400 mg daily. Additionally, ORR was 65%, CR 6%, disease control rate 93 (95% CI, 87 - 97), and resulted in overall tumor size reduction in 96% of patients. Refer to (Table 1) for further details. Conclusion Pralsetinib and Selpercatinib have shown promising anti-tumor activity and an acceptable safety profile in RET fusion-positive NSCLC. However, we cannot draw a firm conclusion regarding which one is better due to insufficient data. Clinical trials, including AcceleRET, are still ongoing, and data is pending. Further comparative studies are needed to derive meaningful survival outcomes.
Electromechanical properties of ternary BiFeO3−0.35BaTiO3-BiGaO3 piezoelectric ceramics
Akram, Fazli,Malik, Rizwan Ahmed,Khan, Salman Ali,Hussain, Ali,Lee, Soonil,Lee, Myang-Hwan,In, Choi Hai,Song, Tae-Kwon,Kim, Won-Jeong,Sung, Yeon Soo,Kim, Myong-Ho Springer-Verlag 2018 JOURNAL OF ELECTROCERAMICS Vol.41 No.1
Sivaramakrishnan Gowri,Abawi Deena,Shoaib Fatima Mohammad,Bucheery Fatema,Salman Ahmed Ali,Kadhem Majeed Jasim,AlSulaiti Fatema,Alsobaiei Muneera,AlSalihi Leena 대한외상학회 2023 大韓外傷學會誌 Vol.36 No.1
Purpose: Dental avulsion injuries have a poor prognosis that largely depends on the immediate steps taken to manage the avulsed tooth. A lack of knowledge about the initial management can lead to tooth loss, with further adverse implications for esthetics, phonetics, and overall growth and function. Hence, the present study aimed to assess parents’ knowledge regarding dental avulsion and the variables associated with their knowledge of avulsion injuries. Methods: A series of closed-ended questions on parents’ knowledge regarding avulsion, such as immediate management, storage media, handling, and urgency of visiting the dentist, was asked. Univariate associations between the outcomes were assessed using the Pearson chi-square test. The chi-square goodness-of-fit test was used to check whether the sample data were representative of the population. Results: In total, 211 mothers and 149 fathers were included, of whom 46.7% had experienced dental trauma during their own childhood. Sixty-one percent of mothers believed that they knew everything necessary about tooth avulsion and its management. A significant number of participants who thought that they had a good level of knowledge about avulsion chose water, tissue, or paper wrap to transport the tooth, and preferred tap water, alcohol, or antiseptic to clean the avulsed tooth.Conclusions: Both mothers and fathers had poor knowledge about tooth avulsion, indicating that there is an immediate need for educational programs focusing on this issue. Since a substantial proportion of participants believed incorrect information, it is vital to disseminate accurate information.