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      • Density based Multiclass Support Vector Machine using IoT driven Service Oriented Architecture for Predicting Cervical Cancer

        Sakthi A,Rajaram M 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.11

        Cervical Cancer stands out among those deadliest diseases, which threatens women in an alarming rate causing approximately 2, 66,000 mortalities per annum worldwide. This cancer can be diagnosed early enough through Pap smear test; a cervical cancer screening program. Finding out the true positive rates of the Cervical Cancer cells with precision is more complex when identifying the same categories of the cancer disease. Various researchers have proposed many approaches over the past four decades and the solutions are pertinent to cervical cancer; however, the challenge remains partially unresolved. The significant contribution of this paper is in two folds, firstly discuss a cloud ready Adapter Driven Service Oriented Architecture (RESPRO 3.0), developed by us for automated screening of Pap Smear can be extended to any International Classification of Diseases (ICD). Secondly, present an Internet of Things (IoT) driven Cervical Cancer prediction adapter built for RESPRO 3.0 based on Density based Multiclass Support Vector Machines (MCSVM) in combination with Polynomial Kernel Trick. The density parameters provide unique space in identifying cervical cancer cell categories compared to exising researches. This cloud solution’s results are bench marked and verified against cyto technician’s ground truth results, found to be highly satisfactory with respect to 93% Sensitivity and 99% Specificity while minimizing test repeatability ratio for the supervised training set of images.

      • KCI등재

        Structural modeling of actuation of IPMC in dry environment: effect of water content and activity

        J. Sakthi Swarrup,Ganguli Ranjan,Madras Giridhar 국제구조공학회 2017 Smart Structures and Systems, An International Jou Vol.19 No.5

        Structural modeling of unencapsulated ionic polymer metal composite (u-IPMC) actuators that are used for flapping the insect scale-flapping wing of micro air vehicles (FMAV) in dry environmental conditions is carried out. Structural modeling for optimization of design parameters for retention of water, maximize actuation performance and to study the influence of water activity on the actuation characteristics of u-IPMC is explored for use in FMAV. The influence of equivalent weight of Nafion polymer, cations, concentration of cations, pre-treatment procedures on retention of water of u-IPMCs and on actuation parameters, flapping angle, flexural stiffness and actuation displacement are investigated. IPMC designed with Nafion having equivalent weight 900-1100, pre-heated at 300C and with sodium as the cations is promising for optimum retention of water and actuation performance. The actuation parameters while in operation in dry and humid environment with varying water activity can be tuned to desirable frequency, deflection, flap angle and flexural stiffness by changing the water activity and operational temperature of the environment.

      • KCI등재

        Effect of zinc oxide incorporation of poly (aniline)-titanium dioxide ternary nanocrystalline photo-anode for dye-sensitized solar cell applications

        Velu Kuppu Sakthi,Kamaraj Eswaran,Sadagopan Jayakumar,Sonaimuthu Mohandoss,Ahmad Naushad,Alagarasan Jagadeesh Kumar,Ravisankar Parkavi,Lee Yong Rok 한국물리학회 2024 Current Applied Physics Vol.58 No.-

        In this work, we have developed optically transparent zinc oxide nanoparticles doped with highly efficient of poly (aniline)-titanium dioxide (PANI/TiO2/ZnO) ternary composites were prepared by simple chemical oxidative polymerization method and its used as photo-anode for dye-sensitized solar cell (DSSC) applications. The as prepared PANI/TiO2/ZnO characterized by the various techniques such as FT-IR, XRD, HR-TEM, SAED, FE-SEM, AFM, and UV–Visible analysis. Morphological analysis was observed in the surface morphology of ZnO doped PANI/TiO2 in crystalline nature. The topographical AFM images were also observed in crystalline nature. Tauc plot analysis were examined the optical band-gap energy (2.95 eV) of PANI/TiO2/ZnO. The DSSCs assembled and as prepared PANI/TiO2, PANI/ZnO, TiO2/ZnO, PANI/TiO2/ZnO were used as photo-anode, 1- hexyl-3-methylimidazolium iodide containing the iodide/triiodide redox mediator used as the electrolyte, platinum paste used as a counter electrode. Among the devices, PANI/TiO2/ZnO photo-anode gives 8.31% efficiency.

      • KCI등재

        Starch Content and Cassava Mosaic Disease Genetic Diversity with Relation to Yield in South Indian Cassava (Manihot esculenta Crantz) Germplasm

        Raghu Duraisamy,Senthil Natesan,Sakthi Ambothi Rathinasamy,Raveendran Muthurajan,Jana Jeevan Ramineni,Nageswari Karuppusamy,Pugalenthi Lakshmanan,Mohan Chokkappan,Karthikeyan Gandhi 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.3

        Cassava, family Euphorbiaceae, is the fifth most important staple food crop. The study of variability and diversity present in diverse cassava accessions maintained at the field genebank of TCRS, TNAU is essential to design the breeding program of cassava in TNAU. Hence, a study was carried out to assess the genetic diversity based on morphological traits and Simple Sequence Repeat (SSR) markers, identifying the SSR markers linked to a cassava mosaic disease-resistant QTL region. Genetic diversity among cassava germplasm accessions was estimated using 28 morphological traits and three SSR markers. The polymorphic information content (PIC) result gives high information for all the SSR markers. Morphological traits revealed 10 clusters and the SSR markers revealed 13 clusters at a similarity coefficient of 2.514 and 0.75, respectively. The SSR marker diversity revealed that the most promising clusters (II and XII) possessing accessions with yield attributing traits and cluster IX were grouped together due to low yield and CMD susceptibility. Morphological descriptors revealed variance for yield contributing traits. The first three principle components accounted for 10.8, 9.1, and 8.4%, respectively. Correlation studies showed significant correlation among yield and yield-attributing traits, which in turn influences yield. The morphological traits diversity reveals that cluster VI was the most promising cluster in which genotypes ME209 and ME460 possess higher yield and starch content with cassava mosaic disease (CMD) resistance. Most of the accessions grouped under cluster X belong to selection from International Centre for Tropical Agriculture (CIAT) collections and the cultivars under clusters I and II were true cassava seed (TCS) selections of India. The CMD-linked SSR marker which is reported in the previous studies have generated eight alleles and each were regressed with CMD resistance and resulted in non-significant linkage to CMD resistance.

      • KCI등재

        Starch Content and Cassava Mosaic Disease Genetic Diversity with Relation to Yield in South Indian Cassava (Manihot esculenta Crantz) Germplasm

        Duraisamy, Raghu,Rathinasamy, Sakthi Ambothi,Natesan, Senthil,Muthurajan, Raveendran,Ramineni, Jana Jeevan,Karuppusamy, Nageswari,Lakshmanan, Pugalenthi,Chokkappan, Mohan,Gandhi, Karthikeyan 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.3

        Cassava, family Euphorbiaceae, is the fifth most important staple food crop. The study of variability and diversity present in diverse cassava accessions maintained at the field genebank of TCRS, TNAU is essential to design the breeding program of cassava in TNAU. Hence, a study was carried out to assess the genetic diversity based on morphological traits and Simple Sequence Repeat (SSR) markers, identifying the SSR markers linked to a cassava mosaic disease-resistant QTL region. Genetic diversity among cassava germplasm accessions was estimated using 28 morphological traits and three SSR markers. The polymorphic information content (PIC) result gives high information for all the SSR markers. Morphological traits revealed 10 clusters and the SSR markers revealed 13 clusters at a similarity coefficient of 2.514 and 0.75, respectively. The SSR marker diversity revealed that the most promising clusters (II and XII) possessing accessions with yield attributing traits and cluster IX were grouped together due to low yield and CMD susceptibility. Morphological descriptors revealed variance for yield contributing traits. The first three principle components accounted for 10.8, 9.1, and 8.4%, respectively. Correlation studies showed significant correlation among yield and yield-attributing traits, which in turn influences yield. The morphological traits diversity reveals that cluster VI was the most promising cluster in which genotypes ME209 and ME460 possess higher yield and starch content with cassava mosaic disease (CMD) resistance. Most of the accessions grouped under cluster X belong to selection from International Centre for Tropical Agriculture (CIAT) collections and the cultivars under clusters I and II were true cassava seed (TCS) selections of India. The CMD-linked SSR marker which is reported in the previous studies have generated eight alleles and each were regressed with CMD resistance and resulted in non-significant linkage to CMD resistance

      • KCI등재

        A Dynamic QoS Model for improving the throughput of Wideband Spectrum Sharing in Cognitive Radio Networks

        ( K. Manivannan ),( C. G. Ravichandran ),( B. Sakthi Karthi Durai ) 한국인터넷정보학회 2014 KSII Transactions on Internet and Information Syst Vol.8 No.11

        This paper considers a wideband cognitive radio network (WCRN) which can simultaneously sense multiple narrowband channels and thus aggregate the detected available channels for transmission and studies the ergodic throughput of the WCRN that operated under: the wideband sensing-based spectrum sharing (WSSS) scheme and the wideband opportunistic spectrum access (WOSA) scheme. In our analysis, besides the average interference power constraint at PU, the average transmit power constraint of SU is also considered for the two schemes and a novel cognitive radio sensing frame that allows data transmission and spectrum sensing at the same time is utilized, and then the maximization throughput problem is solved by developing a gradient projection method. Finally, numerical simulations are presented to verify the performance of the two proposed schemes.

      • SCOPUSKCI등재

        External Beau Radiation Therapy of Adenocarcinoma of the Prostate

        Han Ihn H.,Kanellitsas Christos,Rouere Janice La,Vadivel Sakthi P. The Korean Society for Radiation Oncology 1984 Radiation Oncology Journal Vol.2 No.2

        The record of radiation therapy cases during a five year period at the University of Michigan Hospitals has been analyzed. Of a total of 73 adenocarcinoma of prostate, the majority belonged to Stage B and C which represented 49 and 20 cases, respectively. The mortality rate after irradiation was clearly related to the tumor stage. Local irradiation resulted in $88\%$ of the local control of well·differentiated adenocarcinomas. Stage C cases had $50\%$ mortality, whereas that of Stage B patients was $14\%$. Results of this study are in general agreement with previous data in terms of the local disease control after irradiation and provide a basis for conservative radiotherapy regimen as an approach in the treatment of localized prostatic carcinomas.

      • KCI등재후보

        Superficial brachioulnar artery and its clinical significance

        Jacob Sieger,Lajja Patel,Kabir Sheikh,Emily Parker,Max Sheng,Sumathilatha Sakthi-Velavan 대한해부학회 2019 Anatomy & Cell Biology Vol.52 No.3

        The authors report a rare variation of the vasculature in the upper limbs of an 84-year-old male cadaver. A high bifurcation of the brachial artery occurred bilaterally at the proximal one-third of each arm. The radial arteries were larger than the ulnar arteries and gave origin to the common interosseous arteries. At the cubital fossa, the ulnar arteries traversed medial to the median nerves, continuing superficial to all forearm muscles except the palmaris longus tendon, characteristic of superficial brachioulnar arteries. The aforementioned variations have rarely been reported in previous literature and demonstrate important clinical significance in relation to accidental intra-arterial injections, errors in blood pressure readings, as well as orthopedic, plastic, and vascular surgeries of the upper limbs.

      • KCI등재

        An insight into in vitro strategies for bioproduction of isoflavones

        Vidya Nandakumar,Saravanan Krishnagowdu,Halka Jayachandran,Kowsalya Kumaresan,Preetha Jaganathan Sakthi Yazhini,Gurusaravanan Packiaraj,Radhakrishnan Ramalingam,Nanthini A. Usha Raja,Arun Muthukrishna 한국식물생명공학회 2021 Plant biotechnology reports Vol.15 No.6

        Isoflavones (ISF) are potent secondary metabolites, widely distributed among the members of the Fabaceae family. They have a multitude of biological functions in plants, animals, and humans. Most of the functions exhibited by isoflavones are highly beneficial to human beings. Benefits mainly include lowering cardiovascular diseases, reducing menopausal symptoms, and decreasing the risk of hormone-related cancers. Therefore, this potent compound has emerged as a promising possibility for making medicines and has grabbed the pharmaceutical industry's attention. Nowadays, many isoflavone-based products are manufactured commercially as food supplements, and their demand is drastically increasing globally. Numerous in vitro stud- ies have successfully synthesized value-added metabolites that possess a vast number of industrial applications. Production of isoflavones within the plants depends on several biological and environmental conditions. Hence, in vitro cultures pro- vide an alternate source to recover these compounds independent of environmental factors and limited bio-resources. Plant organ cultures could be highly recommended as a reliable platform for synthesizing plant-based pharmaceutically active isoflavones. Moreover, biotechnological approaches, such as elicitation and precursor feeding, can eventually promote the yield and increase these metabolites' production. This review initially outlines information regarding the source, structure, synthesis, and diverse roles of isoflavones. Later, this paper describes different plant organ cultures for the in vitro production of isoflavones and highlights elicitation strategies as well as metabolic engineering work to enhance production.

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