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Screening strategy for non-alcoholic fatty liver disease
Saisai Zhang,Lung-Yi Mak,Man-Fung Yuen,Wai-Kay Seto 대한간학회 2023 Clinical and Molecular Hepatology(대한간학회지) Vol.29 No.-
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, affecting approximately 25% of the general population worldwide, and is forecasted to increase global health burden in the 21st century. With the advancement of non-invasive tests for assessing and monitoring of steatosis and fibrosis, NAFLD screening is now feasible, and is increasingly highlighted in international guidelines related to hepatology, endocrinology, and pediatrics. Identifying high-risk populations (e.g., diabetes mellitus, obesity, metabolic syndrome) based on risk factors and metabolic characteristics for non-invasive screening is crucial and may aid in designing screening strategies to be more precise and effective. Many screening modalities are currently available, from serum-based methods to ultrasonography, transient elastography, and magnetic resonance imaging, although the diagnostic performance, cost, and accessibility of different methods may impact the actual implementation. A two-step assessment with serum-based fibrosis-4 index followed by imaging test vibration-controlled transient elastography can be an option to stratify the risk of liver-related complications in NAFLD. There is a need for fibrosis surveillance, as well as investigating the cost-effectiveness of different screening algorithms and engaging primary care for first-stage triage screening.
The Effect of Dipping Pretreatment on Ochratoxin A Accumulation in Sultanas and Currants
Xiaoxu Zhang,Jingming Li,Dong Wang,Saisai Feng,Liyan Ma 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.3
The dipping pretreatment on the occurrence of ochratoxin A (OTA) in sultanas and currants was investigated. Grape samples were divided into two groups before a drying process. One group was dipped with potassium carbonate-ethyl oleate, and the other group was left without treatment (the control). OTA were detected using solid-phase extraction clean-up and a high-performance liquid chromatography fluorescence detector. Results showed that OTA content was below the limit of detection in the fresh grapes of both varieties. OTA were not detected in dried vine fruits before storage. However, a real naturally environmental storage revealed that the dipping pretreated samples were contaminated with OTA earlier and to a greater extent than the control. The OTA concentration in the treated and control samples after one-year storage was 0.22 and 0.19 μg/kg for sultanas and 0.34 and 0.21 μg/kg for currants, respectively. These results indicated that dipping pretreatment might increase the toxin contamination and safety risk.
Li Shaoyi,Wang Xiaotian,Zhang Kai,Niu Saisai,Zou Yijun 제어로봇시스템학회 2019 제어로봇시스템학회 국제학술대회 논문집 Vol.2019 No.10
Small infrared moving target detection has an important role in the sea-based infrared search and tracking, maritime area surveillance and other applications. This method aims to detect the small infrared moving targets with the sea-sky background. The present study proposes a detection algorithm for small infrared targets based on the spatio-temporal saliency fusion. The contourlet analysis and edge extraction are carried out in the concurrent design. In order to effectively suppress the background and improve the target signal-clutter ratio, the spectral residual method is combined with the abovementioned methods to reconstruct the target fusion saliency image. Then the target motion region is estimated based on the optical flow method for the fusion saliency image and it is matched with the target area of interest to achieve the moving target detection. Moreover, the pipeline filtering is introduced to achieve the target confirmation by multi-frame judgment, reduce false alarm rate and complete the moving target detection for the infrared image sequence. Experimental results show that the proposed algorithm can achieve continuous target detection and have a higher detection precision via real long wave infrared image sequences.