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L. Feroz Ali,N. Kuppuswamy,R. Soundararajan,K. R. Ramkumar,S. Sivasankaran 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.12
The goal of the present research is to introduce the Tungsten (W) nanoparticles as reinforcement into Al 6063 alloy to produceAl–W nanocomposites by the FSP technique. The vol% of the reinforcement was varied from 3 to 12 with a step of 3,besides the unreinforced Al matrix was considered as 0 vol% for comparison. The role of W nanoparticles in the Al 6063matrix has been exhaustively investigated using advanced characterization techniques such as XRD analysis to observe thephases, FESEM to detect the distribution of reinforcements with their interparticle spacing and the average grain sizes, TEManalysis to study the strengthening factors, new phase formation at the interface between AA 6063 matrix and W particles,the morphology of the W nanoparticles. The achieved average matrix grains size was 42, 2, and 0.9 μm for 0, 6, and 12vol% W nanocomposites, respectively. The obtained results disclosed the uniform dispersion of W nanoparticles, withoutany agglomeration, and with the absence of intermetallic compounds. The hardness and wear resistance of the fabricatednanocomposites were increased incommensurate with the incorporation of heavy metallic W element as reinforcementparticle; which was due to the proper dispersion of W nanoparticles, refinement of matrix grains to ultrafine level, generationof dislocations, and clear interface between Al 6063 matrix and W nanoparticles. In a nutshell, AA 6063–12 vol% Wnanocomposite has achieved the higher hardness (120 HV), lower wear rate (0.13 mm3/m), and friction coefficient (0.33)than other nanocomposites.
Effect of Butyrophilin Gene Polymorphism on Milk Quality Traits in Crossbred Cattle
Bhattacharya, T.K.,Misra, S.S.,Sheikh, Feroz D.,Sukla, Soumi,Kumar, Pushpendra,Sharma, Arjava Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.7
A genetic polymorphism study on butyrophilin gene was carried out to explore variability of this gene and to estimate effects of such variability on milk quality traits in crossbred cattle. Polymorphism was unraveled by conducting Hae III PCR-RFLP of this gene. Three genotypes such as AA, BB and AB and two alleles namely A and B were observed in crossbred population. The frequencies of genotypes and alleles were 0.78, 0.17 and 0.04 for AA, AB and BB genotypes, respectively, and 0.87 and 0.13 for A and B alleles, respectively. The nucleotides, which have been substituted from allele A to B, were observed as C to G ($71^{st}$ nucleotide), C to T ($86^{th}$ nucleotide), A to T ($217^{th}$ nucleotide), G to A ($258^{th}$ nucleotide), A to C ($371^{st}$ nucleotide) and C to T ($377^{th}$ nucleotide). The nucleotide substitutions at $71^{st}$, $86^{th}$ and $377^{th}$ position of the fragment were found as silent mutations whereas nucleotide changes at $217^{th}$, $258^{th}$ and $371^{st}$ positions were detected as substitution of amino acid lysine with arginine, valine with isoleucine, and leucine with proline from allele A to B. The genotypes had significant effects ($p{\leq}0.05$) on total milk solid%, fat%, SNF%, while showing nonsignificant impact on total protein%. AA genotype produced highest average yield for all the traits.
Studies on encapsulation of Rifampicin and its release from chitosan-dextran sulfate capsules
M. Geetha Devi,Susmita Dutta,Ashraf Talib Al Hinai,S. Feroz 한국화학공학회 2015 Korean Journal of Chemical Engineering Vol.32 No.1
Biodegradable capsules of size around 350 nm were prepared by layer-by-layer (L-b-L) assembly of oppo-sitely charged chitosan and dextran sulfate on silica particles and the subsequent removal of template. The resultingcapsules were loaded with rifampicin, an anti-tuberculosis drug under modest conditions, as demonstrated by scan-ning electron microscopy (SEM). Maximum encapsulation of rifampicin was found to be about 82 µg at 25 oC and pHof 3. Release studies were done in-vitro mode by semiautomatic release protocol, with different pH solutions in waterand phosphate buffered saline (PBS). The microcapsules exhibited a slow and sustained release over 72 hours and max-imum release was obtained at a pH of 1.2 in water and a pH of 7.4 in PBS. The size of silica particle was analyzed bydynamic light scattering method. Scanning electron microscopy (SEM) measurements showed the surface morphol-ogy of the hollow capsules. UV spectroscopy was employed to monitor the drug release processes in both solutions. The kinetics of drug release mechanism was studied using Ritger-Peppas and Higuchi models.