Protective Effects of Sea Spaghetti-Enriched Restructured Pork Against Dietary Cholesterol: Effects on Arylesterase and Lipoprotein Profile and Composition of Growing Rats

Adriana R. Schultz Moreira,Raúl Olivero-David,Miguel Vázquez-Velasco,Laura González-Torres,Juana Benedí,Sara Bastida,Francisco J. Sánchez-Muniz 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.8

There is a general assumption that seaweeds are hypocholesterolemics and antioxidants. However, controversial results suggest specific properties for each individual alga. This study aims to assess the effect of including Sea Spaghetti alga (S) in a restructured-pork (RP) diet, both enriched and not enriched with dietary cholesterol, on arylesterase (AE) activity and lipoprotein concentration and composition of Wistar rats. Four groups of 10 growing male Wistar rats were each fed a mix of 85% AIN-93M diet and 15% freeze-dried RP for 5 weeks. The control group (C) consumed control RP-C; the S group consumed RP-S with 5% seaweeds; the Chol-C group consumed the C diet but enriched with cholesterol (2.43%) and cholic acid (0.49%); the Chol-S group consumed the S diet but enriched with cholesterol and cholic acid. AE activity was five times higher (P < .01) in S compared with C rats, but three times lower in Chol-S compared with Chol-C rats (P < .01). The Chol-C diet induced hypercholesterolemia but reduced triglycerides (TG), giving rise to the presence of very low-density lipoprotein (VLDL) that was enriched in cholesterol. The Chol-S diet partially blocked (P < .001) the hypercholesterolemic induction of the Chol-C diet, and reduced TG levels (P < .05) with respect to S rats. The cholesterol supplementation increased total cholesterol, VLDL-cholesterol, and intermediate-density lipoprotein + LDL-cholesterol (IDL + LDL)-cholesterol (P < .001) in Chol-C rats, but the effect was lower in the Chol-S diet. In conclusion, RP-S increases the antioxidant capacity within a noncholesterol enriched diet while improving the lipoprotein profile within a cholesterol-enriched diet.

The United States and Asia : A New Strategic Framework for the 1990s

Bell, David S. 동국대학교 행정대학원 1993 행정논집 Vol.21 No.-

For over forty-five years, U.S. involvement in the Asia-Pacific arena was predicated on : (1) a Cold War commitment to Asia-Pacific security with Japn as the critical linchpin: and (2) the extraordinary economic power of the United States. However, as all of us have witnessed in the closing years of the previous decade and the opening years of the current one, these two foreign policy premises are no longer viable in the new Asia-Pacific era. Superpower rapprochement began the process of enormous change in the security environment, and this culminated in the end of the Cold War with the sudden and dramatic dissolution of the Soviet Union December 1991. An expansionist revolutionary¸ global power, a once eminent threat to the world no longer existed. Less suddenly, but equally dramatic in consequences, was the sapping of American economic strength by excessively bloated defense budgets as essential to Cold War strategy, especially under President Reagan and continued in part by his successor President Bush. From economic supremacy as the world’s number one creditor, the Uuited States became the world’s number one debtor nation in the course of approximately ten years, Now with a changing security environment in the Asia-Pacific arena, containment is obviously not a pressing requirement, and with the decline of American economic power there has been a phenomenal growth of Asia-Pacific economic power led by japan and the four tigers(dragons or gang of four) namely S. Korea, Hong Kong, Singapore and Taiwan and two cubs, Malaysia and Thailand and this requires that the U.S. must now come to terms with the changing reality of new security objectives.

Strongly modulated transmission of a spin-split quantum wire with local Rashba interaction

Sá,nchez, David,Serra, Llorenç,Choi, Mahn-Soo American Physical Society 2008 Physical review. B, Condensed matter and materials Vol.77 No.3

Antibacterial Properties of Honey Produced by Melipona beecheii and Apis mellifera against Foodborn Microorganisms

David Chan-Rodríguez,Jesús Ramón-Sierra,Jorge Lope-Ayora,Enrique Sauri-Duch,Luis Cuevas-Glory,Elizabeth Ortiz-Vázquez 한국식품과학회 2012 Food Science and Biotechnology Vol.21 No.3

The aim of this study was to determine the antibacterial activity in vitro of Melipona and Apis honey against various foodborne microorganisms. The results of qualitative test showed that Melipona honey inhibited both Staphylococcus aureus ATCC25923 and H08M06 strains and both Escherichia coli ATCC35922 and H12K06 strains. Apis honey inhibited both E. coli ATCC35922 and H12K06strains and S. aureus ATCC25923 strain. Minimum inhibitory concentrations of Melipona honey (5-16%, w/v) were lower than those of Apis honey (15-31%, w/v). This study demonstrated that the antibacterial potency of Melipona honey could be a new alternative for controlling foodborne illness.

Electronic properties of carbon nanotube/fabric composites

David S. Hecht,Liangbing Hu,George Gr?ner 한국물리학회 2007 Current Applied Physics Vol.7 No.1

Single walled carbon nanotube (SWNT)/fabric composite materials were manufactured using two simple manufacturing processes. Thetransfer technique. The composite retains high mechanical strength (governed by the fabric), and good electrical properties (determinedby the nanotubes). We measure the DC electrical conductivity of the composite fabric to be 5.33 S/cm for the sprayed tubes, 13.8 S/cmfor the incubated SWNTs, and 8 S/cm for the QLB transferred tubes; these values are limited not by the nanotube network, but by thesurface roughness of the fabric itself. Measurements of the conductivity up to 1 MHz reveal a transport process that proceeds along a ran-.C)andmechanicaldeformations.Theconductivityofthecompositedecreasesbylessthan10%whenbentaroundacylinder of1 cmdiameter.

Extracorporeal Shock Wave Therapy Combined with Vascular Endothelial Growth Factor-C Hydrogel for Lymphangiogenesis

Kim, In Gul,Lee, Ji Youl,Lee, David S.,Kwon, Jeong Yi,Hwang, Ji Hye S. Karger AG 2013 Journal of vascular research Vol.50 No.2

<P>Abstract</P><P><B><I>Background/Aims:</I></B> Lymphedema is a clinically incurable disease that occurs commonly after lymph node dissection and/or irradiation. Several studies have recently demonstrated that extracorporeal shock wave therapy (ESWT) could promote lymphangiogenesis associated with expression of vascular endothelial growth factor (VEGF)-C. This research concerned primarily the synergistic effect of ESWT combined with VEGF-C incorporated hydrogel (VEGF-C hydrogel) combination therapy for promoting lymphangiogenesis and ultimately alleviating lymphedema. <B><I>Methods:</I></B> The VEGF-C hydrogel was applied to the injury site in a mouse model of lymphedema and then regularly underwent ESWT (0.05 mJ/mm<SUP>2</SUP>, 500 shots) every 3 days for 4 weeks. <B><I>Results:</I></B> Four weeks after the treatment, mice treated with VEGF-C hydrogel and ESWT showed signs of the greatest decrease in edema/collagenous deposits when compared with the other experimental group. LYVE-1-positive vessels also revealed that the VEGF-C/ESWT group had significantly induced the growth of new lymphatic vessels compared to the other groups. Western blot analysis showed that expression of VEGF-C (1.24-fold) and VEGF receptor-3 (1.41-fold) was significantly increased in the VEGF-C/ESWT group compared to the normal group. <B><I>Conclusion:</I></B> These results suggested that VEGF-C and ESWT had a synergistic effect and were very effective in alleviating the symptoms of lymphedema and promoting lymphangiogenesis.</P><P>Copyright © 2012 S. Karger AG, Basel</P>

Effect of a Soluble Cocoa Fiber-Enriched Diet in Zucker Fatty Rats

David Sánchez,Leila Moulay,Begon˜a Muguerza,Mar Quin˜ones,,Amaya Aleixandre 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.3

The effects of a soluble cocoa fiber (SCF) were studied in Zucker fatty rats. Two groups of Zucker fatty rats were fed the following diets: standard diet and 5% SCF-enriched diet. A group of Zucker lean rats fed the standard diet was used for results comparison with obese Zucker animals. Solid and liquid intakes, body weight, plasma glucose, lipid profile, and systolic (SBP) and diastolic (DBP) blood pressure were recorded weekly. At the end of the experimental period insulin was determined, and fat apparent digestibility (FAD) and insulin resistance were calculated. The Zucker fatty rats fed 5% SCF-enriched diet showed less weight gain and food intake than those fed the standard diet. The group fed the fiber-enriched diet showed lower values of the total cholesterol/high-density lipoprotein cholesterol ratio and triglyceride levels than the standard group. FAD was also lower in the fiber group. Both SBP and DBP were decreased. In addition, SCF reduced plasma glucose and insulin, and as a consequence the insulin resistance was also decreased. Our data demonstrate that SCF resulted in an improvement of the studied risk factors associated with cardiometabolic disorders.

Photorhabdus luminescens subsp. akhurstii SL0708 pathogenicity in Spodoptera frugiperda (Lepidoptera: Noctuidae) and Galleria mellonella (Lepidoptera: Pyralidae)

Julián David Salazar-Gutiérrez,Andrés Castelblanco,María Ximena Rodríguez-Bocanegrab,Wilson Teran,Adriana Sáenz-Aponte 한국응용곤충학회 2017 Journal of Asia-Pacific Entomology Vol.20 No.4

Entomopathogenic nematodes are key players for insect pest control and constitute an environmentally friendly alternative for crop protection. The insecticidal activity of the family Heterorhabditidae relies on a tight symbiotic relationship with enterobacteria of the genus Photorhabdus, where the bacterial contribution towards the death of the host has been highlighted. In the present work, we report the identification and pathogenic characterization of Photorhabdus luminescens strain SL0708, which is the natural symbiont of Heterorhabditis indica SL0708. We evaluated the pathogenicity of whole bacterial cells and acellular extracts against both Spodoptera frugiperda larvae and Galleria mellonella. Phylogenetic analyses using a polygenic sequencing approach assigned the bacterial strain to Photorhabdus luminescens subsp. akhurstii and bioassays showed it is highly pathogenic for both insects. After 48 h of treatment with 1× 103 −1 × 104 CFU/larva, 100% mortality was attained. Furthermore, when intra- or extracellular bacterial extracts were injected into G. mellonella, a cumulative percent mortality of 63% and 100% was respectively obtained after 72 h. In contrast, a 10% and 93% mortality was achieved for S. frugiperda with intra and extracellular extracts, respectively highlighting the role of extracellular factors in pathogenicity. We detected extracellular activities potentially accounting for the high pathogenicity observed and these included; proteases, esterases, ureases, hemolysins and siderophores. Interestingly, S. frugiperda was more susceptible to P. luminescens SL0708 cells than G. mellonella, which contrasted to its higher resistance to H. indica SL0708 nematodes, which suggests that EPN biological control potential should also be evaluated based on bacterial symbiont pathogenicity

Most Rev. Pablo Virgilio S. David

Pablo Virgilio S,David 신학과사상학회 2018 가톨릭 신학과 사상 Vol.- No.81

관찰대상중심적(person - centered) 접근을 통한 청소년비행의 발달궤적 연구

정익중,Daniel S. Nagin,J. David Hawkins,Karl G. Hill 한국사회복지연구회(서울대학교 사회복지연구소) 2001 사회복지연구 Vol.17 No.1

본 연구의 목적은 관찰대상중심적 (person-centered) 접근중의 하나인 혼합형 모형 (mixture modeling)을 적용하여 청소년비행의 발달궤적(developmental trajectories)을 분석하는 것이다. 본 연구는 1985년부터 현재까지 진행중인 Seattle Development Project에서 수집된 15년간의 종단적 패널자료를 이용하였다. 기존 연구의 주류를 이루는 관찰변수중심적(variable-centered) 접근에서는 모든 청소년들에게 일률적으로 적용되는 평균 발달경로를 밝히는데 중점을 두는데 반하여, 이 연구는 혼합형 모형의 일종인 준모수적 집단중심모형(semi-parametric group-based modeling)을 사용하여 청소년비행의 다양한 발달궤적을 제시하였다. 본 연구결과 청소년비행에는 5가지 형태의 발달궤적-만성형 비행청소년(chronic offender), 점증형 비행청소년(escalator), 중단형 비행청소년(desister), 후발형 비행청소년(late onsetter), 비(非)비행청소년(non offender)-이 존재하는 것으로 밝혀졌다. 이 관찰대상중심적 발달궤적 연구는 다음과 같은 실천적 함의를 제공한다. 첫째, 성인기에 심각한 범죄를 유발하기 쉬운 환경에 노출되어 있는 청소년들을 사전에 발견할 수 있도록 도와준다. 둘째, 청소년비행의 상이한 발달궤적에 영향을 미치는 독특한 보호 및 위험요소들이 무엇인지 분석할 수 있다. 따라서 본 연구결과는 청소년들의 상이한 발달궤적에 따른 적절한 비행예방 프로그램 개발에 적극적으로 활용될 수 있는 사회사업적 실천지침을 제공한다.