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Kim, Hyeonjin,Thompson, Richard B.,Allen, Peter S. Elsevier 2012 Journal of magnetic resonance Vol.223 No.-
<P>The performance of multiple quantum filters (MQFs) can be disappointing when the background signal also arises from coupled spins. Moreover, at 3.0 T and even higher fields the majority of the spin systems of key brain metabolites fall into the strong-coupling regime. In this manuscript we address comprehensively, the importance of the phase of the multiple quantum coherence-generating pulse (MQ-pulse) in the design of MQFs, using both product operator and numerical analysis, in both zero and double quantum filter designs. The theoretical analyses were experimentally validated with the examples of myo-inositol editing and the separation of glutamate from glutamine. The results demonstrate that the phase of the MQ-pulse per se provides an additional spectral discrimination mechanism based on the degree of coupling beyond the conventional level-of-coherence approach of MQFs. To obtain the best spectral discrimination of strongly-coupled spin systems, therefore, the phase of the MQ-pulse must be included in the portfolio of the sequence parameters to be optimized.</P>
Intelligent Robust Base-Station Research in Harsh Outdoor Wilderness Environments for Wildsense
( Junho Ahn ),( Akshay Mysore ),( Kati Zybko ),( Caroline Krumm ),( Dohyeon Lee ),( Dahyeon Kim ),( Richard Han ),( Shivakant Mishra ),( Thompson Hobbs ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.3
Wildlife ecologists and biologists recapture deer to collect tracking data from deer collars or wait for a drop-off of a deer collar construction that is automatically detached and disconnected. The research teams need to manage a base camp with medical trailers, helicopters, and airplanes to capture deer or wait for several months until the deer collar drops off of the deer’s neck. We propose an intelligent robust base-station research with a low-cost and time saving method to obtain recording sensor data from their collars to a listener node, and readings are obtained without opening the weatherproof deer collar. We successfully designed the and implemented a robust base station system for automatically collecting data of the collars and listener motes in harsh wilderness environments. Intelligent solutions were also analyzed for improved data collections and pattern predictions with drone-based detection and tracking algorithms.
Jong S. Kim,Yeon-Jung Kim,Kyung Bok Lee,Jae-Kwan Cha,Jong-Moo Park,Yang-Ha Hwang,Eung-Gyu Kim,Joung-Ho Rha,Jaseong Koo,Jei Kim,Yong-Jae Kim,Woo-Keun Seo,김동억,Thompson G. Robinson,Richard I. Lindley,Xia 대한뇌졸중학회 2018 Journal of stroke Vol.20 No.1
Background and Purpose Following the positive results from recent trials on endovascular therapy (EVT), bridging therapy (intravenous alteplase plus EVT) is increasingly being used for the treatment of acute ischemic stroke. However, the optimal dose of intravenous alteplase remains unknown in centers where bridging therapy is actively performed. The optimal dose for eventual recanalization and positive clinical outcomes in patients receiving bridging therapy also remains unknown. Methods In this prospective Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED) sub-study, we explored the outcomes following treatment with two different doses (low- [0.6 mg/kg] or standard-dose [0.9 mg/kg]) of intravenous alteplase across 12 Korean centers where EVT is actively performed. The primary endpoint was a favorable outcome at 90 days (modified Rankin Scale scores 0 to 1). Secondary endpoints included symptomatic intracerebral hemorrhage (ICH) in all patients, and the recanalization rate and favorable outcome in patients who underwent cerebral angiography for EVT (ClinicalTrials.gov, number NCT01422616). Results Of 351 patients, the primary outcome occurred in 46% of patients in both the standard- (80/173) and low-dose (81/178) groups (odds ratio [OR], 1.14; 95% confidence interval [CI], 0.72 to 1.81; P=0.582), although ICHs tended to occur more frequently in the standard-dose group (8% vs.3%, P=0.056). Of the 67 patients who underwent cerebral angiography, there was no significant difference in favorable functional outcome between the standard- and low-dose groups (39% vs.21%; OR, 2.39; 95% CI, 0.73 to 7.78; P=0.149). Conclusions There was no difference in functional outcome between the patients receiving different doses of alteplase in centers actively performing bridging therapy.