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RISS 인기검색어
- 검색키워드
- 저자 : Reza Torshizi (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
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Experimental and numerical investigations of radial flow compressor component losses
Mohammad Mojaddam,Ali Hajilouy-Benisi,S. Abolfazl Moussavi-Torshizi,Mohammad Reza Movahhedy,Mohammad Durali 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.6
This research numerically and experimentally investigates a small turbocharger radial flow compressor with a vane-less diffuser andvolute. The geometry of the compressor is obtained via component scanning, through which a 3D model is prepared. The flow inside thismodel is numerically analyzed by using a Navier-Stokes solver with a shear-stress transport turbulence model. The characteristic curvesof the compressor and the contributions of its components to total pressure drop are acquired by measuring the static and total pressuresat different cross sections of the compressor. Numerical results are verified with the experimental test results. The model results exhibitgood agreement with the experimental results. In particular, the results show that the losses related to the impeller are higher than thoserelated to the stationary components at different conditions, with the former causing a decline of at least 15% in compressor isentropicefficiency. The contribution of stationary components to efficiency decrease is approximately 4.8% at maximum efficiency mass flowrate and is limited to 7.1%. At low mass flow rates, the contribution of the diffuser to efficiency decline is higher than that of the volute. This finding is reversed at high mass flow rates. The performances of the diffuser and the volute are also studied by exploring total pressureand static pressure recovery coefficients, as well as the net radial force on the impeller shaft under a wide operating range.
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Evaluation of the role of TAX, HBZ, and HTLV-1 proviral load on the survival of ATLL patients
Mohammad Mehdi Akbarin,Abbas Shirdel,Alireza Bari,Seyedeh Tahereh Mohaddes,Houshang Rafatpanah,Ehsan Ghayour Karimani,Kobra Etminani,Amin Golabpour,Reza Torshizi 대한혈액학회 2017 Blood Research Vol.51 No.2
Background: Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy with very poor prog-nosis and short survival, caused by the human T-lymphotropic virus type-1 (HTLV-1). The HTLV-1 biomarkers trans-activator x (TAX) and HTLV-1 basic leucine zipper factor (HBZ) are main oncogenes and life-threatening elements. This study aimed to assess the role of the TAX and HBZ genes and HTLV-1 proviral load (PVL) in the survival of patients with ATLL. Methods: Forty-three HTLV-1-infected individuals, including 18 asymptomatic carriers (AC) and 25 ATLL patients (ATLL), were evaluated between 2011 and 2015. The mRNA expression of TAX and HBZ and the HTLV-1 PVL were measured by quantitative PCR. Results: Significant differences in the mean expression levels of TAX and HBZ were observed be-tween the two study groups (ATLL and AC, P=0.014 and P=0.000, respectively). In addi-tion, the ATLL group showed a significantly higher PVL than AC (P=0.000). There was a significant negative relationship between PVL and survival among all study groups (P=0.047). Conclusion: The HTLV-1 PVL and expression of TAX and HBZ were higher in the ATLL group than in the AC group. Moreover, a higher PVL was associated with shorter survival time among all ATLL subjects. Therefore, measurement of PVL, TAX, and HBZ may be beneficial for monitoring and predicting HTLV-1-infection outcomes, and PVL may be useful for prog-nosis assessment of ATLL patients. This research demonstrates the possible correlation between these virological markers and survival in ATLL patients.
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Evaluation of the role of TAX, HBZ, and HTLV-1 proviral load on the survival of ATLL patients
Mohammad Mehdi Akbarin,Abbas Shirdel,Alireza Bari,Seyedeh Tahereh Mohaddes,Houshang Rafatpanah,Ehsan Ghayour Karimani,Kobra Etminani,Amin Golabpour,Reza Torshizi 대한혈액학회 2017 Blood Research Vol.52 No.2
Background: Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy with very poor prog-nosis and short survival, caused by the human T-lymphotropic virus type-1 (HTLV-1). The HTLV-1 biomarkers trans-activator x (TAX) and HTLV-1 basic leucine zipper factor (HBZ) are main oncogenes and life-threatening elements. This study aimed to assess the role of the TAX and HBZ genes and HTLV-1 proviral load (PVL) in the survival of patients with ATLL. Methods: Forty-three HTLV-1-infected individuals, including 18 asymptomatic carriers (AC) and 25 ATLL patients (ATLL), were evaluated between 2011 and 2015. The mRNA expression of TAX and HBZ and the HTLV-1 PVL were measured by quantitative PCR. Results: Significant differences in the mean expression levels of TAX and HBZ were observed be-tween the two study groups (ATLL and AC, P=0.014 and P=0.000, respectively). In addi-tion, the ATLL group showed a significantly higher PVL than AC (P=0.000). There was a significant negative relationship between PVL and survival among all study groups (P=0.047). Conclusion: The HTLV-1 PVL and expression of TAX and HBZ were higher in the ATLL group than in the AC group. Moreover, a higher PVL was associated with shorter survival time among all ATLL subjects. Therefore, measurement of PVL, TAX, and HBZ may be beneficial for monitoring and predicting HTLV-1-infection outcomes, and PVL may be useful for prog-nosis assessment of ATLL patients. This research demonstrates the possible correlation between these virological markers and survival in ATLL patients.
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