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도시공원 이용자들의 형태 분석 및 이용 만족도에 관한 연구
박장근(Jang Geun Park),임란희(Ran Hee Lim),지용범(Yong Beom Ji),신희진(Hee Jin Shin) 한국여가레크리에이션학회 2001 한국여가레크리에이션학회지 Vol.21 No.-
The purpose of this study was to investigate of form analysis and extent of Satisfaction of people using park. For this study, the population was the user Mansuck Park in Suwon City from 06.06.2001 to 06.07.2001. Sampling was made according to the self-administration method The participants in the questionnaire were 224. From the analysis of data, this study reached the following coclusions. 1. An analysis of form ; 1) A walking was 53.1 percent according to the analysis of using form in traffic means. There were some differences by age, job, education level, income. 2) The evening was 41.5 percent , and the afternoon was 28.6 percent according to the time period of using. There were some differences in all items as gender, age, job, education level, income. 3) The family or relative was 48.2 percent, and the friends (lover) was 32.6 percent according to the companion. There were some differences in all items as gender, age, job, education level, income. 4) The rest and walk 50.0 percent , and meeting, talk was 17.4 percent according to the using park. There were some differences by gender, age, job, income. 5) The shade of a tree, bench, grass was 55.4 percent, and the promenade was 23.7 percent according to the place and facilities for using. There were some differences by age. 2 And extent of satisfaction for using park ; The satisfaction in the location of facilities, the management and scene of the park was in high content degree. But, the satisfaction in the number of facilities and the staff was in low content degree.
Tae-Yang Noh,Beom-Hee Lee,Byeong-Mok Park1,Ah-Ran Cha,Hee-Chul Yang 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.2
Nuclear power plants in Korea stores approximately 3,800 drums of paraffin solidification products. Due to the lack of homogeneity, these solidification products are not allowed to be disposed of. There is therefore a need for the separation of paraffin from the solidification products. This work developed an equipment for a selective separation of paraffin from the solidification product using the vacuum evaporation and condensational recovery method in a closed system. The equipment mainly consists of a vacuum evaporator and a condensational deposition recovery chamber. Nonisothermal vacuum TGAs, kinetic analyses and kinetic predictions were conducted to set appropriate operation conditions. Its basic operability under the established conditions was first confirmed using pure paraffin solid. Simulated paraffin solidification product fixing dried boric acid waste including nonradioactive Co and Cs were then fabricated and tested for the capability of selective separation of paraffin from the simulated waste. Paraffin was selectively separated without entertainment of Co and Cs. It was confirmed that the developed equipment could separate and recover paraffin in the form of nonradioactive waste.
The identification of optimum condition for direct regeneration in black raspberry
Ran, Choi-Heh,Park, Pill-Jae,Lee, Hee-Kwon,Joong, Yun-Song,Lee, In-Sok The Korean Society of Plant Biotechnology 2008 식물생명공학회지 Vol.35 No.2
Adventitious buds appeared within 2 weeks on the base of the petiole explants and increased for two months. A maximum of regeneration (15.6%) was obtained on the medium containing $1.5\;{\mu}M$ TDZ in combination with $1\;{\mu}M$ IBA. To know which explants are the best for the induction of regeneration, three explants such as leaf, petiole and leaf-petiole were used. Among the explant types, the leaf-petiole explant was significantly more effective than leaf and petiole for promoting adventitious shoots, with leaf-petiole inducing at the highest regeneration frequency (33.7%). The regeneration frequency of adventitious shoots in the leaf-petiole explants was significantly affected by leaf size and the position of explants. The leaf-petiole smaller than 5 mm leaf in width was induced at the highest regeneration frequency (68.9%). The smaller leaf sizes, the greater regeneration frequency. Also when the leaves are nearer to the shoot tip, the regeneration frequency is higher. When the rooted micro-shoots were transferred to the soil after growing for 6 weeks in the media, the survival rate was 90%.
Park, Sang-Hoon,Lee, Mi-Ran,Kim, Tae-Suk,Baek, Sang-Ki,Jin, Sang-Jin,Kim, Jin-Wook,Jeon, Sang-Gon,Yoon, Ho-Baek,Lee, Joon-Hee The Korean Society of Animal Reproduction 2014 Reproductive & developmental biology Vol.38 No.4
Differentiated nuclei can experimentally be returned to an undifferentiated embryonic status after nuclear transfer (NT) to unfertilized metaphase II (MII) oocytes. Nuclear reprogramming is triggered immediately after somatic cell nucleus transfer (SCNT) into recipient cytoplasm and this period is regarded as a key stage for optimizing reprogramming. In a recent study (Dai et al., 2010), use of m-carboxycinnamic acid bishydroxamide (CBHA) as a histone deacetylase inhibitor during the in vitro early culture of murine cloned embryos modifies the acetylation status of somatic nuclei and increases the developmental competence of SCNT embryos. Thus, we examined the effects of CBHA treatment on the in vitro preimplantation development of porcine SCNT embryos and on the acetylated status of histone H3K9 on cloned embryos at the zygote stage. We performed the three groups SCNT: SCNT (NT), CBHA treatment at the porcine fetus fibroblast cells (PFFs) used as donor cells prior to SCNT (CBHA-C) and CBHA treatment at the porcine SCNT embryos during the in vitro early culture after oocyte activation (CBHA-Z). The PFFs were treated with a $15{\mu}M$ of CBHA (8 h) for the early culture and the porcine cloned embryos were treated with a $100{\mu}M$ concentration of CBHA during the in vitro early culture (10 h). Cleavage rates and development to the blastocyst stage were assessed. No significant difference was observed the cleavage rate among the groups (82.6%, 76.4% and 82.2%, respectively). However, the development competence to the blastocyst stage was significantly increased in CBHA-Z embryos (22.7%) as compared to SCNT and CBHA-C embryos (8.6% and 4.1%)(p<0.05). Total cell numbers and viable cell numbers at the blastocyst stage of porcine SCNT embryos were increased in CBHA-Z embryos as compared to those in CBHA-C embryos (p<0.05). Signal level of histone acetylation (H3K9ac) at the zygote stage of SCNT was increased in CBHA-Z embryos as compared to SCNT and CBHA-C embryos. The results of the present study suggested that treatment with CBHA during the in vitro early culture (10 h) had significantly increased the developmental competence and histone acetylation level at the zygote stage.
( Hee Seung Hong ),( Jiwon Baek ),( Jae Chul Park ),( Ho-su Lee ),( Dohoon Park ),( A-ran Yoon ),( Soo Jung Park ),( Sung Noh Hong ),( Seong-joon Koh ),( Chang Kyun Lee ),( Bo-in Lee ),( Sung Wook Hwa 대한소화기기능성질환·운동학회 2022 Gut and Liver Vol.16 No.6
Background/Aims: Chronic enteropathy associated with SLCO2A1 gene (CEAS), an inherited disease characterized by nonspecific intestinal ulcers, has emerged in the Japanese population via loss-of-function mutations in the SLCO2A1 gene. We aimed to investigate the clinical and genetic characteristics of Korean patients diagnosed with CEAS. Methods: From July 2018 to July 2021, we performed Sanger sequencing of the SLCO2A1 gene in 46 patients with chronic intestinal ulcers. CEAS was confirmed based on known SLCO2A1 mutations. We summarized the clinical characteristics of patients with confirmed CEAS. Results: Fourteen out of 46 patients (30.4%) had genetically confirmed CEAS, and two SLCO2A1 variants were detected (splicing site variant c.940+1G>A and nonsense mutation [p.R603X] in SLCO2A1). Twelve patients (85.7%) were females and the median age at diagnosis of CEAS was 44.5 years. All patients presented with abdominal pain, and 13 patients (92.9%) presented with anemia (median hemoglobin, 9.6 g/dL). Ten patients (71.4%) had hypoalbuminemia (median, 2.7 g/dL). The most commonly involved site was the ileum (13/14, 92.9%). Manifestations of primary hypertrophic osteoarthropathy (PHO), such as digital clubbing, pachydermia, and periostosis were observed in five patients (28.6%) and two male patients and one female patient satisfied all major PHO diagnostic criteria. Conclusions: The clinical and genetic characteristics of Korean patients with confirmed CEAS were similar to those reported in the literature. CEAS should be considered in the differential diagnosis for patients with unexplained chronic nonspecific ulcers of the small intestine. (Gut Liver 2022;16:942-951)
Improvement of Spatial Resolution in Nano-Stereolithography Using Radical Quencher
Park, Sang-Hu,Lim, Tae-Woo,Yang, Dong-Yol,Kim, Ran-Hee,Lee, Kwang-Sup The Polymer Society of Korea 2006 Macromolecular Research Vol.14 No.5
The improvement of spatial resolution is a fundamental issue in the two-photon, polymerization-based, laser writing. In this study, a voxel tuning method using a radical quencher was proposed to increase the resolution, and the quenching effect according to the amount of radical quencher was experimentally investigated. Employing the proposed method, the lateral resolution of the line patterns was improved almost to 100 nm. However, a shortcoming of the quenching effect was the low mechanical strength of polymerized structures due to their short chain lengths. Nano-indentation tests were conducted to evaluate quantitatively the relationship between mechanical strength and the mixture ratio of the radical quencher into the resins. The elastic modulus was dramatically reduced from an average value of 3.015 to 2.078 GPa when 5 wt% of radical quencher was mixed into the resin. Three-dimensional woodpile structures were fabricated to compare the strength between the resin containing radical quencher and the original resin.
Park, Chi-Min,Lee, Woo Yong,Chun, Ho-Kyung,Cho, Yong Beom,Yun, Hae Ran,Heo, Jin Seok,Yun, Seong Hyeon,Kim, Hee Cheol Wiley Subscription Services, Inc., A Wiley Company 2010 Journal of surgical oncology Vol.101 No.1
<B>Background</B><P>The aim of this study was to determine whether the different polymorphisms in the thymidylate synthase (TS) gene, novel G>C single nucleotide polymorphism (SNP) and variable number of tandem repeat (VNTR), may be related with disease-free survival (DFS) in patients with stage III colorectal cancer receiving adjuvant chemotherapy.</P><B>Methods</B><P>The study included 201 patients with pathologic TNM stage III colon cancer who received adjuvant 5-fluorouracil (5-FU)-based chemotherapy after surgery. DNA was extracted from fresh tumor tissue and sequenced. Patients with TS genotypes of 2R3G, 3C3G, or 3G3G were assigned to a high expression group, and those with 2R2R, 2R3C, or 3C3C, to a low expression group.</P><B>Results</B><P>Frequencies of the TS tandem repeat polymorphisms among the tumor genotypes were 6.0% in 2R2R, 25.4% in 2R3R, and 68.7% in 3R3R. The low expression group included 52 patients (25.9%), and the high expression group included 149 patients (74.1%). Groups classified according to possession of VNTR, SNP, and low- or high-expression genotypes did not differ significantly in DFS. In multivariate analysis, only tumor stage showed significant prognostic value (hazard ratio (HR) 2.05, 95% CI = 1.24–3.37, P = 0.005).</P><B>Conclusions</B><P>TS polymorphisms do not predict clinical outcome of colorectal cancer patients treated with adjuvant 5-FU-based chemotherapy. J. Surg. Oncol. 2010;101:22–27. © 2009 Wiley-Liss, Inc.</P>
Park, Chung-Hwa,Kim, Hee Yeon,Lee, Sung Won,Song, Do Seon,Song, Myeong Jun,Kwon, Jung Hyun,You, Chan Ran,Jang, Jeong Won,Kim, Chang Wook,Choi, Sang Wook,Bae, Si Hyun,Choi, Jong Young,Yoon, Seung Kew Wolters Kluwer Health, Inc. All rights reserved. 2016 European journal of gastroenterology & hepatology Vol.28 No.10
<P>Background and aimsEntecavir (ETV) is a potent nucleoside analogue with high genetic barrier to resistance. In this study, real-life clinical experiences in the long-term use of ETV and the durability of its off-treatment effectiveness were analyzed.Materials and methodsThis study was based on a large real-life cohort of 2240 chronic hepatitis B patients treated with ETV between January 2006 and December 2012 using a centralized electronic data repository.ResultsAmong 2240 patients, 804 patients were treatment naive and underwent ETV monotherapy. Their mean treatment duration was 712493 days, with a cumulative proportion of patients achieving HBV DNA less than 300copies/ml in 85.8, 95.7, and 97.6% at years 1, 2, and 3, respectively. Predictors for earlier virologic response were female sex, lower HBV DNA, higher alanine transaminase, lower platelet count, and HBeAg negativity at baseline. In patients who achieved virologic response and HBeAg loss, the cumulative relapse rate was 91.3% in 2 years after the cessation of treatment. During the treatment, 34 patients developed hepatocellular carcinoma, among whom 30 patients had cirrhosis before treatment initiation. ETV treatment showed efficient virologic response as the treatment duration was extended, but off-treatment efficacy was not durable, and the antiviral treatment showed some limitation in preventing hepatocellular carcinoma among liver cirrhosis patients, implying that treatment cessation should be taken into consideration more carefully.ConclusionThis study from a real-life cohort may provide data on treating chronic hepatitis B patients more close to everyday clinical practice.</P>