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Ramazan Asmatulu,Zeinab Veisi,Md. Nizam Uddin,Anil Mahapatro 한국섬유공학회 2019 Fibers and polymers Vol.20 No.5
Highly sensitive, reliable and practical detection of Cyclooxygenase-2 (COX-2) as an important enzyme in painbiomarkers, inflammation, and cancer cell proliferation is of great importance. This study demonstrates the feasibility ofdeveloping nanobiosensor (or biosensor) platforms for sensitive COX-2 biomarker detection from phosphate buffer saline(PBS) and human serum samples. Highly porous polyaniline nanofibers were fabricated in four different average diametersusing electrospinning process. They were then integrated as the main sensing component into interdigitated goldmicroelectrodes to develop label-free electrochemical nanobiosensors. The performance of the nanobiosensors was evaluatedin comparison with a plain control biosensor using electrochemical impedance spectroscopy (EIS). Significant improvementwas observed in the sensitivity of the nanofiber-based biosensors revealing the remarkable capability of electrospunpolyaniline nanofiber in robust and rapid detection of the COX-2 biomarker. The fabricated nanofiber-based biosensors wereable to detect the target antigen with concentrations as low as 0.01 pg/ml in PBS and human serum samples, respectively. High sensitivity, as well as remarkable selectivity towards COX-2 analyte, suggested the excellent potential of this nanofiberbasedplatform for reliable COX-2 analyte detection.
Modal analysis and improvement of lightweight wings for micro air vehicle (MAV) applications
Vibhakar Seewoogolam,Brijesh Prasad,Avi Raj Manral,Ibrahim M Alarifi,Ramazan Asmatulu 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.1
Micro air vehicles (MAVs) are small portable flying machines designed to perform some specific tasks. Presently, the MAVs are being highly considered in applications like defense, security, environment protection, wildlife conservation, toy industry, construction, traffic management, and at times of disaster. Efforts were done in the past and are still being taken up to fulfill the need for smart MAVs. The authors examined a lightweight, safe wing using poly (vinyl chloride) PVDF and polyvinylidene fluoride PVC by using the electrospinning technique. The flapping test at room temperature tested the wings, and improved performance was observed in the heat-treated samples in comparison to non-heat treated samples. The modal analysis technique was also applied to understand the wings' safe working conditions, helpful in predicting the safe working conditions by the ANSYS software. The present study can be useful for designing and manufacturing new generation MAV wings for different applications.