http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Anil Mahapatro (검색결과 1 건)
- 무료
- 기관 내 무료
- 유료
-
Ramazan Asmatulu,Zeinab Veisi,Md. Nizam Uddin,Anil Mahapatro 한국섬유공학회 2019 Fibers and polymers Vol.20 No.5
Highly sensitive, reliable and practical detection of Cyclooxygenase-2 (COX-2) as an important enzyme in painbiomarkers, inflammation, and cancer cell proliferation is of great importance. This study demonstrates the feasibility ofdeveloping nanobiosensor (or biosensor) platforms for sensitive COX-2 biomarker detection from phosphate buffer saline(PBS) and human serum samples. Highly porous polyaniline nanofibers were fabricated in four different average diametersusing electrospinning process. They were then integrated as the main sensing component into interdigitated goldmicroelectrodes to develop label-free electrochemical nanobiosensors. The performance of the nanobiosensors was evaluatedin comparison with a plain control biosensor using electrochemical impedance spectroscopy (EIS). Significant improvementwas observed in the sensitivity of the nanofiber-based biosensors revealing the remarkable capability of electrospunpolyaniline nanofiber in robust and rapid detection of the COX-2 biomarker. The fabricated nanofiber-based biosensors wereable to detect the target antigen with concentrations as low as 0.01 pg/ml in PBS and human serum samples, respectively. High sensitivity, as well as remarkable selectivity towards COX-2 analyte, suggested the excellent potential of this nanofiberbasedplatform for reliable COX-2 analyte detection.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
