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      • KCI등재

        하악전돌증에서 하악지 시상분할골절단 및 Screw고정후 골성회귀에 관한 연구

        김명래,최장우,윤정훈,이창국 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.4

        Skeletal and dental changes were examined in 38 patients of mandibular prognathism who been treated by a bilateral sagittal split osteotomy(SSRO) and internal fixation using titanium mini-screws. All patients were followed up for over 8 months after the surgeries, and postoperative cephalometric measurements were compared at 2 months and at 8 months. Linear measurements of the “Pog-most posterior screws” and angular measurementsts of “SN-Pog”were compared to figure out the change of bony fragments. The significancy of data were tested by unpaired T-test. The results were as follows : 1. The fixation screws were changed in cephalometric position as little as 0.32 2.51㎜ in SSRO and 0.15 1.00㎜ in SSRO & Le Fort I Osteotomy.(P<0.05) 2. Mandibular set-back over 5㎜ resulted in less stability of the fixation screws and higher relapse tendency. 3. The internal fixation using two screws along the inferior border and one on the superior ridge is considered to be very resistant to postoperative relapse of the repositioned bony segments.

      • 정신과 문제로 병사용 진단서를 발급받은 환자들의 임상적 특징

        장혁진,김학렬,박상학,김상훈,조용래,표경식 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

        Background and Objectives : Most Korean young men should take a military physical examination. This study attempted to search the social, economical and psychological features of Korean youths who have psychiatric problems in taking the military physical examination. So this study was intended to help decide whether the youths enter the military service or not. Materials and Methods : This study analyzed diagnostic features that were grouped by 7 categories (antisocial and borderline personality disorder group, the other personality disorders group, psychosis group, organic mental disorder group, neurosis group, pervasive developmental disorders group, the other groups). The study was conducted from 1994 to May 1999 at Chosun University hospital with about 143 patients who were issued the psychiatric certificate for military affairs. Results : According to the results of the psychiatric examination, the antisocial and borderline personality disorder group had increased more year by year than the other groups. Classified by the residential distribution, the residents of agricultural areas belonged to the psychosis group more than others. Classified by the job distribution, the antisocial and borderline personality disorder group had more gangsters than the other groups. Also the pervasive developmental disorders group included those Who were without an occupation. Classified by visiting companion, those who were included in the antisocial and borderline personality disorder group and pervasive developmental disorders group used to come alone as compared with the other groups. In the case of those who have experienced psychiatric treatment in the past and who have been treated psychiatrically after being given the psychiatric certificate, the psychosis group comprised more than 50% statistically. In the case of the existence of a tattoo and self-injured scars, the antisocial and borderline personality disorder group has more than the others statistically. According to psychological examination, by measure of validity scale of MMPI, the antisocial and borderline personality disorder group appeared as the inverted V shape that L, K value was low and F value was high. And the antisocial and borderline personality disorder group measured by the Pd, Pa measure. Pd, Pa measure value got higher points than the organic mental disorder group statistically. Conclusion : The number of the antisocial and borderline personality disorder patients’ visits increased at the psychiatric hospital year by year and there were many gangsters or persons without regular occupation in that kind of patients’group. And there were many visitors who came by themselves to the hospital. Also they tended to have a tattoo or self-injured scars. And most of patients didn’t do commuting psychiatric care after receiving the psychiatric certificate. In the aspect of the psychological examination, they were likely to exaggerate their symptoms or disguise having psychiatric trouble intentionally.

      • SCISCIESCOPUS

        Evaluation of antitumor activity of Artemisia capillaris extract against hepatocellular carcinoma through the inhibition of IL-6/STAT3 signaling axis

        Jang, Eungyeong,Kim, So-Young,Lee, Na-Rae,Yi, Chae-Min,Hong, Da-Rong,Lee, Woo Seok,Kim, Jong-Ho,Lee, Kyung-Tae,Kim, Bum-Joon,Lee, Jang-Hoon,Inn, Kyung-Soo NATIONAL HELLENIC RESEARCH FOUNDATION 2017 ONCOLOGY REPORTS Vol.37 No.1

        <P>Interleukin-6 (IL-6)/signal transducer and activator of transcription 3 (STAT3) signaling pathway plays critical roles in the development and progression of hepatocellular carcinoma (HCC). Artemisia capillaris (AC) has been widely used to treat various liver diseases including HCC as a herbal medicine. The effects of AC on IL-6/STAT3 signaling axis in HCC cells and subsequent anticancer activity of AC against HCC were analyzed using HCC cell lines and HBV W4P-LHB-expressing NIH3T3 cell line, which has been shown to gain tumorigenicity by activating IL-6/STAT3 signaling in our previous study. AC extract significantly suppressed the growth and colony formation of HCC cells. In addition, it inhibited the activation of STAT3 by IL-6 and subsequent synthesis of downstream molecules in HCC and W4P-NIH3T3 cells. Consequently, migration of cells was significantly suppressed by the AC extract. Collectively, the findings suggest that AC extract is capable of conferring various antitumor effects against HCC through the modulation of the IL-6/STAT3 pathway. The results provide a basis for the therapeutic use of AC in the treatment of HCC. Identification of the compound responsible for the effect may lead to the development of a novel anticancer agent against HCC.</P>

      • KCI등재

        천왕보심단이 정상인의 심박변이도에 미치는 영향에 대한 예비연구

        강래엽 ( Rae Yeop Kang ),김현진 ( Hyun Jin Kim ),한효정 ( Hyo Jung Han ),박은영 ( Eun Young Park ),장정아 ( Jeong A Jang ),서호석 ( Ho Seok Seo ),김진원 ( Jin Won Kim ),강현선 ( Hyun Sun Kang ),김지훈 ( Jee Hoon Kim ),조소현 ( So 대한한방신경정신과학회 2009 동의신경정신과학회지 Vol.20 No.4

        Objectives: This study was conducted to assess the effect of Chunwangbosim-dan(CB) on the autonomic nervous system by using heart rate variability measurement. Methods: The eligible subjects were composed of the healthy female group of ages 25 to 30 years. They were divided into two groups, the CB group(n=16) and the control group(n=16). We measured the heart rate variability respectively for 3 times at 14:00, 16:00, and 17:00. In the CB group, subjects were administered CB at 15:00. For the measurement values, Mean Heart Rate and SDNN(standard deviation of the NN intervals) were used as time domain analysis, and HF(high frequency), LF(low frequency), and LF/HF ratio were used as frequency domain analysis. Results: The degree of LF changes in the CB group was significantly lower than control group at 1 hour after administration. Conclusions: We suggest that Chunwangbosim-dan may be useful for stabilization of the autonomic nervous system by controlling sympathetic nerve in healthy people.

      • KCI등재

        下顎顆頭骨折 治療後의 豫後에 關한 臨床的硏究

        Myung Rae Kim(金命來),Jang Hoon Lee(李章薰) 대한구강악안면외과학회 1986 대한구강악안면외과학회지 Vol.12 No.1

        This is a clinical study on the prognosis after the surgical or non-surgical management of condylar fractures of the mandible, by reviewing recent results of 43 patients followed-up for at least 6 months after the treatment in Ewha University Hospital from 1976 to 1985. The results were as follows; 1. Of 43 cases, 20.9% (9 cases) showed marked limitation of jaw excursion less than 30㎜ in interincisal opening; 18.6% (8 cases) followed by moderate temporomandibular joint dysfunction; 60.5% (26 cases) had no evidence of jaw dysfunction. 2. 47.0% of all disturbances in jaw excursion occurred in condylar head, 41.2% (7 cases) were in condylar neck, and only 1 case was in subcondylar portion. 3. Incidences of posttreatment disorders by the level of fractures were as 72.7% (8 of 11 cases) in condylar head, 26.9% (7 of 26 cases) in condylar neck, and only 1 case of 6 reductions in subcondylar fractures. 4. By the method of reduction, 58.8% of 17 complicated cases occurred after open reduction and 41.1% of them were after the closed reduction. And their incidences by number of treatments were as 46.0% of 23 open-reductions, while 35.0% of 20 closed-reductions. 5. Comparing the progonosis after the management by the level of fractures; ⅰ) Open reduction of condylar head fractures was followed by 77.7% (7 of 9 cases) of jaw dysfunctions, and closed reduction by only 1 of 2 cases. ⅱ) Open reduction of condylar neck fractures was followed by 30.0% (3 of 10 cases) of disorders, and closed reduction by 31.2% (5 of 16 cases) of dysfunctions. ⅲ) There was no complications after the open reduction of subcondylar fractures, and only 1 case of 2 closed-reductions. 6. By the period of intermaxillary fixation, relatively higher incidence of jaw-movement limitation was followed after 4-week-fixation(47.0%) and 6-week-fixation(42.8%) than 2- week-fixation (none of 6 cases) and 3-week-fixation (2 of 8 cases). But 3 of 5 cases of 1 -week-fixation, showed severe complications.

      • KCI등재

        인공이식재 MEDPOR 를 이용한 중안모증가술(PARANASAL AUGMENTATION)과 측모의 변화

        정상훈,최장우,김명래,이창국,김선종 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.2

        With the increasing esthetic requirement in orthognathic surgeries, midfacial corrective surgeries were developed to improve the paranasal depression. Augmentation with autogenous bones has long been the standard in facial reconstruction, however limited graft availability, donor site morbidity, and difficulties in 3-dimensional shaping were led to limited use. Porous high density polyethylene(Medpor) was introduced in the 1970s as an alloplastic implants. It can be used in various size and shapes, and shortend operation time. The purpose of this study is to determine, by means of cephalometrics, the degree of long term stability and gaining of the overlying soft tissue thickness. The results were as followings : 1. There was no evidence of foreign body reaction, infection, and tissue necrosis. 2. Medpor implants had an advantage of clinical use ; easy to contour and adapt to obtain a precise 3-dimensional construction. 3. Cephalometric study of 16 cases of paranasal augmentation revealed an overall increase of soft tissue thickness of approximately 82.1% in 6-months following. 4. The successful results could be obtained under the aseptic handling.

      • Magnetic and Microstructural Characteristics of a DyF<tex> $_{3}$</tex> Dip-Coated Nd-Fe-B Sintered Magnet

        Kyoung-Hoon Bae,Tae-Hoon Kim,Seong-Rae Lee,Seok NamKung,Tae-Suk Jang IEEE 2013 IEEE transactions on magnetics Vol.49 No.7

        <P>We investigated the microstructural and magnetic property changes of DyF<SUB>3</SUB> dip-coated Nd-Fe-B sintered magnets as a function of the first post-sintering annealing (PSA) temperature and clarified the optimum first PSA temperature for the dip-coating process. Coercivity increased (from 26.7 to 29.06 kOe) with increasing first PSA temperature (from 700 to 900°C) owing to the increased diffusion depth of the Dy atoms. In the diffused region, the formation of the rare earth-rich phase (Nd-Dy-O) was suppressed and the core-shell microstructure was developed as a result of the DyF<SUB>3</SUB> dip-coating process. However, coercivity decreased when the samples were annealed at 950°C because h-Nd<SUB>2</SUB>O<SUB>3</SUB> phases were formed in the Cu-rich triple junction phase and the grain boundary phase. By contrast, the C-Nd<SUB>2</SUB>O<SUB>3</SUB> phase, which is closely related to coercivity enhancement after second PSA, was formed in the magnet annealed at 900°C. The result fulfilled our basic aim of utilizing the DyF<SUB>3</SUB> dip-coating process in order to enhance the coercivity of Nd-Fe-B sintered magnets without remanence reduction.</P>

      • KCI등재

        강우 발생에 의한 진동만해역의 육상오염원이 해수 및 패류에 미치는 영향 분석

        이장원 ( Jang Won Lee ),윤민철 ( Minchul Yoon ),김지훈 ( Ji Hoon Kim ),조성래 ( Sung Rae Jo ),남기호 ( Ki Ho Nam ),하광수 ( Kwang Soo Ha ),박큰바위 ( Kunbawui Park ) 한국수산과학회 2023 한국수산과학회지 Vol.56 No.6

        In this study, we evaluated the impacts of land-based pollution sources on seawater and shellfish in the Jindongman area after 20.5 mm and 90.6 mm rainfall events. We analyzed sanitary indicator microorganisms used in survey management, such as total coliform, fecal coliform, Escherichia coli, and male-specific coliphage in Waste water treatment plant (WWTP), major inland pollution source,s seawater, and shellfish for 4 days after rainfall events. Our results showed that the range of coliform group and fecal coliform was 1.8-49 and <1.8-4.5 MPN (most probable number)/100 mL, respectively, after rainfall events in WWTP discharge water. Furthermore, the radius of the calculated impacted area of major inland pollution sources ranged from 5 to 798 m after 20.5 mm of rainfall and 30 to 1,031 m after 90.6 mm of rainfall. The fecal coliform of seawater at 30 stations in the shellfish growing area and areas adjacent to four stations was <1.8-130 and from <1.8-79 MPN/100 mL, respectively. The E. coli level of shellfish at 7 stations in the shellfish growing area was <18-220 MPN/100 g.

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