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RISS 인기검색어
- 검색키워드
- 저자 : R.M. Abdel Hameed (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
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Studies on Υ-irradiated polymer–nano calcined clay blended cement mortar composites
M.R. Ismail,E. Hamed,H.A. Abdel-Rahman,M.M. Younes,S.H. El-Hamouly 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.2
This study focuses on the preparation of blended cement mortars by a partial replacement of Portland cement by different ratios of nano-calcined clay. Also, the addition of PVA on blended cement mortar with different percentages. In addition to the influence of different doses of gamma rays on the physicochemical properties of the blended cement composites; the specimens are cured under tap water. Results showed that, compressive strength and bulk density of the composites increased with increasing the irradiation dose and PVA contents for certain values while, total porosity behaved in an opposite direction. XRD, SEM, TGA confirmed these conclusions.
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Development of electroless Ni–P modified aluminum substrates in a simulated fuel cell environment
Amani E. Fetohi,K.M. El-Khatib,R.M. Abdel Hameed 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.30 No.-
The corrosion resistance of electroless Ni–P coating on pure Al, Al 6061, Al 3004 and Al 1050 is examinedin an environment simulated to PEM fuel cell. Potentiodynamic polarization techniques, Interfacialcontact resistance, surface morphology, chemical composition of coated substrates and EISmeasurements have been investigated. Modified Al 1050 showed reduction in its corrosion currentdensity by 44.69 times. It also showed the best stability of all modified Al substrates. The formed Ni–Player on Al 1050 is thicker by about 3 times, relative to that on Al 6061 and has higher Ea value of135.68 kJ mol 1 supporting its lower corrosion rate.
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Anti-proliferative Activities of Metallic Nanoparticles in an in Vitro Breast Cancer Model
Loutfy, Samah A,Al-Ansary, Nadia A,Abdel-Ghani, Nour T,Hamed, Ahmed R,Mohamed, Mona B,Craik, James D,Eldin, Taher A. Salah,Abdellah, Ahmed M,Hussein, Yassmein,Hasanin, MTM,Elbehairi, Serag Eldin I Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.14
Aims: To investigate effect of metallic nanoparticles, silver (AgNPs) and gold nanoparticles (AuNPs) as antitumor treatment in vitro against human breast cancer cells (MCF-7) and their associated mechanisms. This could provide new class of engineered nanoparticles with desired physicochemical properties and may present newer approaches for therapeutic modalities to breast cancer in women. Materials and Methods: A human breast cancer cell line (MCF-7) was used as a model of cells. Metallic nanoparticles were characterized using UV-visible spectra and transmission electron microscopy (TEM). Cytotoxic effects of metallic nanoparticles on MCF-7 cells were followed by colorimetric SRB cell viability assays, microscopy, and cellular uptake. Nature of cell death was further investigated by DNA analysis and flow cytometry. Results: Treatment of MCF-7 with different concentrations of 5-10nm diameter of AgNPs inhibited cell viability in a dose-dependent manner, with IC50 value of $6.28{\mu}M$, whereas treatment of MCF-7 with different concentrations of 13-15nm diameter of AuNPs inhibited cell viability in a dose-dependent manner, with IC50 value of $14.48{\mu}M$. Treatment of cells with a IC50 concentration of AgNPs generated progressive accumulation of cells in the S phase of the cell cycle and prevented entry into the M phase. The treatment of cells with IC50 concentrations of AuNPs similarly generated progressive accumulation of cells in sub-G1 and S phase, and inhibited the entrance of cells into the M phase of the cell cycle. DNA fragmentation, as demonstrated by electrophoresis, indicated induction of apoptosis. Conclusions: Our engineered silver nanoparticles effectively inhibit the proliferation of human breast carcinoma cell line MCF-7 in vitro at high concentration ($1000{\mu}M$) through apoptotic mechanisms, and may be a beneficial agent against human carcinoma but further detailed study is still needed.
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Amr E. El Hakim,Sobhy Abdel-Shafy,Amira M. K. Abouelella,Ragaa R. Hamed,Yasser E. Shahein 대한수의학회 2011 JOURNAL OF VETERINARY SCIENCE Vol.12 No.3
In order to identify antigens that can help prevent camel tick infestations, three major glycoproteins (GLPs) about 97, 66 and 40 kDa in size were purified from adult and larval Egyptian ticks, Hyalomma (H.) dromedarii, using a single-step purification method with Con-A sepharose. The purified GLPs were evaluated as vaccines against camel tick infestation in rabbits. The rabbits received three intramuscular inoculations of GLPs (20 μg/animal) on days 0, 14, and 28. In the immunoblot analysis, Sera from the immunized rabbits recognized the native GLPs and other proteins from larval and adult H. dromedarii ticks along with those from other tick species such as Rhipicephalus sanguineus but not Ornithodoros moubata. The effects of immunity induced by these GLPs were determined by exposing rabbits to adult H. dromedarii ticks. These results demonstrated that GLP immunization led to a slightly decreased reproductive index and significantly reduced rates of egg hatchability. These results demonstrated that immunization with the purified GLPs can provide protection against infestation by H. dromedarii and some other tick species. Further studies are needed to confirm the effectiveness of immunization with GLPs against other tick species.
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