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      • miR-421, miR-155 and miR-650: Emerging Trends of Regulation of Cancer and Apoptosis

        Farooqi, Ammad Ahmad,Qureshi, Muhammad Zahid,Coskunpinar, Ender,Naqvi, Syed Kamran-Ul-Hassan,Yaylim, Ilhan,Ismail, Muhammad Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.5

        It is becoming progressively more understandable that between transcription and translation there lies another versatile regulator that quantitatively controls the expression of mRNAs. Identification of miRNAs as key regulators of wide ranging signaling cascades and modulators of different cell-type and context dependent activities attracted basic and clinical scientists to study modes and mechanisms in details. In line with this approach overwhelmingly increasing in vivo and in vitro studies are deepening our understanding regarding miR-421, mir-155 and miR-650 mediated regulation of cellular activities. We also attempt to provide an overview of long non coding RNAs.

      • KCI등재

        Experimental investigation of aerosols removal efficiency through self-priming venturi scrubber

        Suhail Ali,Khalid Waheed,Kamran Qureshi,Naseem Irfan,Masroor Ahmed,Waseem Siddique,Amjad Farooq 한국원자력학회 2020 Nuclear Engineering and Technology Vol.52 No.10

        Self-priming venturi scrubber is one of the most effective devices used to collect aerosols and soluble gas pollutants from gaseous stream during severe accident in a nuclear power plant. The present study focuses on investigation of dust particle removal efficiency of the venturi scrubber both experimentally and theoretically. Venturi scrubber captures the dust particles in tiny water droplets flowing into it. Inertial impaction is the main mechanism of particles collection in venturi scrubber. The water injected into venturi throat is in the form of jets through multiple holes present at venturi throat. In this study, aerosols removal efficiency of self-priming venturi scrubber was experimentally measured for different operating conditions. Alumina (Al2O3) particles with 0.4-μm diameter and 3950 kg/m3 density were treated as aerosols. Removal efficiency was calculated for different gas flow rates i.e. 3-6 m3/h and liquid flow rates i.e. 0.009–0.025 m3/h. Experimental results depict that aerosols removal efficiency increases with the increase in throat velocity and liquid head. While at lower air flow rate of 3 m3/h, removal efficiency decreases with the increase in liquid head. A theoretical model of venturi scrubber was also employed and experimental results were compared with mathematical model. Experimental results are found to be in good agreement with theoretical results.

      • KCI등재

        Study of an improved and novel venturi scrubber configuration for removal of radioactive gases from NPP containment air during severe accident

        Farooq Mujahid,Ahmed Ammar,Qureshi Kamran,Shah Ajmal,Waheed Khalid,Siddique Waseem,Irfan Naseem,Ahmad Masroor,Farooq Amjad 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.9

        Owing to the rising concerns about the safety of nuclear power plants (NPP), it is essential to study the venturi scrubber in detail, which is a key component of the filtered containment venting system (FCVS). FCVS alleviates the pressurein containment byfiltering and venting out the contaminated air. Themain objective of this research was to perform a CFD investigation of different configurations of a circular, non-submerged, selfpriming venturi scrubber to estimate and improve the performance in the removal of elemental iodine from the air. For benchmarking, a mass transfer model which is based on two-film theory was selected and validated by experimental data where an alkaline solution was considered as the scrubbing solution. This mass transfer model was modified and implemented on a unique formation of two self-priming venturi scrubbers in series. Euler-Euler method was used for two-phase modeling and the realizable K ε model was used for capturing the turbulence. The obtained results showed a remarkable improvement in the removal of radioactive iodine from the air using a series combination of venturi scrubbers. The removal efficiency was improved at every single data point.

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        Investigation of dust particle removal effi ciency of self-priming venturi scrubber using computational fl uid dynamics

        Sarim Ahmed,Hassan Mohsin,Kamran Qureshi,Ajmal Shah,Waseem Siddique,Khalid Waheed,Naseem Irfan,Masroor Ahmad,Amjad Farooq 한국원자력학회 2018 Nuclear Engineering and Technology Vol.50 No.5

        A venturi scrubber is an important element of Filtered Containment Venting System (FCVS) for theremoval of aerosols in contaminated air. The present work involves computational fluid dynamics(CFD) study of dust particle removal efficiency of a venturi scrubber operating in self-priming mode usingANSYS CFX. Titanium oxide (TiO2) particles having sizes of 1 micron have been taken as dust particles. CFD methodology to simulate the venturi scrubber has been first developed. The cascade atomizationand breakup (CAB) model has been used to predict deformation of water droplets, whereas the EulerianeLagrangian approach has been used to handle multiphase flow involving air, dust, and water. Thedeveloped methodology has been applied to simulate venturi scrubber geometry taken from the literature. Dust particle removal efficiency has been calculated for forced feed operation of venturi scrubberand found to be in good agreement with the results available in the literature. In the second part, venturiscrubber along with a tank has been modeled in CFX, and transient simulations have been performed tostudy self-priming phenomenon. Self-priming has been observed by plotting the velocity vector fields ofwater. Suction of water in the venturi scrubber occurred due to the difference between static pressure inthe venturi scrubber and the hydrostatic pressure of water inside the tank. Dust particle removal efficiencyhas been calculated for inlet air velocities of 1 m/s and 3 m/s. It has been observed that removalefficiency is higher in case of higher inlet air velocity.

      • KCI등재

        Study of hydrodynamics and iodine removal by self-priming venturi scrubber

        Ahad Jawaria,Rizwan Talha,Farooq Amjad,Waheed Khalid,Ahmad Masroor,Qureshi Kamran Rasheed,Siddique Waseem,Irfan Naseem 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.1

        Filtered containment system is a passive safety system that controls the over-pressurization of containment in case of a design-based accidents by venting high pressure gaseous mixture, consisting of air, steam and radioactive particulate and gases like iodine, via a scrubbing system. An indigenous lab scale facility was developed for research on iodine removal by venturi scrubber by simulating the accidental scenario. A mixture of 0.2 % sodium thiosulphate and 0.5 % sodium hydroxide, was used in scrubbing column. A modified mathematical model was presented for iodine removal in venturi scrubber. Improvement in model was made by addition of important parameters like jet penetration length, bubble rise velocity and gas holdup which were not considered previously. Experiments were performed by varying hydrodynamic parameters like liquid level height and gas flow rates to see their effect on removal efficiency of iodine. Gas holdup was also measured for various liquid level heights and gas flowrates. Removal efficiency increased with increase in liquid level height and gas flowrate up to an optimum point beyond that efficiency was decreased. Experimental results of removal efficiency were compared with the predicted results, and they were found to be in good agreement. Maximum removal efficiency of 99.8% was obtained.

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