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RISS 인기검색어
- 검색키워드
- 저자 : Platanias, Leonidas C. (검색결과 4 건)
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Mechanisms of Type-I Interferon Signal Transduction
Uddin, Shahab,Platanias, Leonidas C. Korean Society for Biochemistry and Molecular Biol 2004 Journal of biochemistry and molecular biology Vol.37 No.6
Interferons regulate a number of biological functions including control of cell proliferation, generation of antiviral activities and immumodulation in human cells. Studies by several investigators have identified a number of cellular signaling cascades that are activated during engagement of interferon receptors. The activation of multiple signaling cascades by the interferon receptors appears to be critical for the generation of interferon mediated biological functions and immune surveillance. The present review summarizes the existing knowledge on the multiple signaling cascades activated by Type I interferons. Recent developments in this research area are emphasized and the implications of these new discoveries on our understanding of interferon actions are discussed.
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Mechanisms of Type-I Interferon Signal Transduction
Uddin, Shahab,Platanias, Leonidas C. 한국생화학분자생물학회 (구 한국생화학회) 2004 BMB Reports Vol.37 No.6
Interferons regulate a number of biological functions including control of cell proliferation, generation of antiviral activities and immumodulation in human cells. Studies by several investigators have identified a number of cellular signaling cascades that are activated during engagement of interferon receptors. The activation of multiple signaling cascades by the interferon receptors appears to be critical for the generation of interferon-mediated biological functions and immune surveillance. The present review summarizes the existing knowledge on the multiple signaling cascades activated by Type I interferons. Recent developments in this research area are emphasized and the implications of these new discoveries on our understanding of interferon actions are discussed.
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Saini Aarti,Kashif Muhammad,Platania Silvia 한국마케팅과학회 2023 마케팅과학연구 Vol.33 No.4
There is a limited amount of research to investigate emotional transition (i.e. love to hate) among consumers. Moreover, can valueexpressiveness motivate consumers to not to share negative word of mouth (NWOM) despite hating a brand? This study aims at addressing these important research questions. Survey-based data is collected from 413 Indian luxury fashion consumers and analyzed via structural equation modelling technique, using AMOS 27.0. Findings reveal that brand jealousy mediates the relationship between brand love and brand hate. Furthermore, when value expressiveness is low, the relationship between brand hate and negative word of mouth is stronger. Brand marketers should strengthen symbolic brand identity to sustain positive consumerbrand emotions. Moreover, some relationship dyads can be used to establish the brand image in a family-oriented, collectivist culture. The mediation of brand jealousy and the moderation of NWOM are unique contributions of this study in an Indian context.
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( Vanessa Gowreesunkar ),( Hugues Seraphin ),( Mustafeed Zaman ),( Marco Platania ) 한국문화관광학회 2018 문화관광연구 Vol.20 No.2
Purpose - Our objective is twofold: First, to identify what can cause local residents dissatisfaction with events and tourism in rural communities. Second, show that the level of happiness of the local residents can mitigate their dissatisfaction with the tourism industry and event development. Design/methodology/approach - In terms of methodology, this paper is based on primary data collected using a questionnaire. SPSS has been used to run some descriptive analysis Practical implication - Existing literature discuss mainly the contribution of events and tourism to destinations and local residents as a one-way contribution or impact with events and tourism impacting or contributing to the local community and destination overall. We are arguing that in some cases, the direction of the impact or contribution goes the other way round. It is the resilience of local residents that enable events and tourism to grow and remain. Quality of life or happiness should systematically be used as a metric by DMOs to assess their performance Originality / value - Happiness and/or Quality of Life and tourism are very topical at the moment and still poorly researched. This research paper is therefore going to contribute to the meta-literature in the area. Last but not least, there is absolutely no research paper on tourism and events based on Winchester (UK).
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