http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Le-Phuc Nguyen,Yen Thi Hai Pham,Phuong Thuy Ngo,Tri Van Tran,Loc Vinh Tran,Nam Thi Hoai Le,Luong Huu Nguyen,Tung Thanh Dang,Duc Anh Nguyen,Marco Wenzel,David Hartmann,Karsten Gloe,Jan J. Weigand,Klaus 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.5
Acid leaching and a two-step solvent extraction procedure were developed to produce high purity mixture of La and Ce from iron-rich spent FCC catalyst discharged from Dzung Quat refinery (Vietnam). Acid leaching of the spent catalyst with 2M HNO3 and a solid-to-liquid ratio of 1/3 at 80 oC in 1 h dissolved almost 90% of La while 12% of Al and 25% of Fe were transferred to the leachate. The extraction of RE metals and main impurities such as Al and Fe by a mixture of di-2-ethylhexyl phosphoric acid (D2EHPA) and tributyl phosphate (TBP) was investigated. Experiments showed that it was necessary to remove Fe before extracting RE and the optimum extraction conditions for a high recovery of RE while 0% of Al extraction were pH1, contact time=10min, and D2EHPA/TBP volume ratio= 4 : 1. At these conditions, the extraction yields of La(III) and Ce(III) were 72% and 89%, respectively. A two-step solvent extraction was developed to achieve a high purity of RE mixture, which included (1) the removal of impurity Fe by 25% (v/v) diisooctyl phosphinic acid (DiOPA) in n-octane for 140 min, (2) the extraction of rare earths by a mixture of di-2-ethylhexyl phosphoric acid (D2EHPA) and tributyl phosphate (TBP) in n-octane for 10 min without the need for adjusting the pH of the leaching solution.
Huan, Le Cong,Tran, Phuong-Thao,Phuong, Cao Viet,Duc, Phan Huy,Anh, Duong Tien,Hai, Pham The,Huong, Le Thi Thu,Thuan, Nguyen Thi,Lee, Hye Jin,Park, Eun Jae,Kang, Jong Soon,Linh, Nguyen Phuong,Hieu, Tr Elsevier 2019 Bioorganic chemistry Vol.92 No.-
<P><B>Abstract</B></P> <P>In search for novel small molecules with antitumor cytotoxicity via activating procaspase-3, we have designed and synthesized three series of novel (E)-<I>N</I>′-benzylidene-4-oxoquinazolin-3(4<I>H</I>)-yl)acetohydrazides (<B>5a-j, 6a-h,</B> and <B>7a-h)</B>. On the phenyl ring ò the benzylidene part, three different substituents, including 2-OH-4-OCH<SUB>3</SUB>, 4-OCH<SUB>3</SUB>, and 4-N(CH<SUB>3</SUB>)<SUB>2</SUB>, were introduced, respectively. Biological evaluation showed that the acetohydrazides in series <B>5a-j</B>, in which the phenyl ring of the benzylidene part was substituted by 2-OH-4-OCH<SUB>3</SUB> substituent, exhibited potent cytotoxicity against three human cancer cell lines (SW620, colon; PC-3, prostate; NCI-H23, lung). Most of the compounds, in this series, especially compounds <B>5c, 5b</B> and <B>5h,</B> also significantly activated caspase-3 activity. Among these, compound <B>5c</B> displayed 1.61-fold more potent than PAC-1 as caspase-3 activator. Cell cycle analysis showed that compounds <B>5b</B>, <B>5c</B>, and <B>5h</B> significantly arrested the cell cycle in G1 phase. Further apoptotic studies also demonstrated compounds <B>5b</B>, <B>5c</B>, and <B>5h</B> as strong apoptotic cell death inducers. The docking simulation studies showed that these compounds could activate procaspase <I>via</I> chelating Zn<SUP>2+</SUP> ion bound to the allosteric site of the zymogen.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Novel (<I>E</I>)-<I>N</I>′-benzylidene-2-(4-oxoquinazolin-<I>3(4H)-yl</I>)acetohydrazides were synthesized. </LI> <LI> The acetohydrazides <B>5a-i</B> exhibited potent cytotoxicity against three human cancer cell lines. </LI> <LI> A number of cytotoxic compounds exhibited good caspase activation activity. </LI> <LI> The cytotoxic compounds were shown to arrest cells at G1 phase. </LI> <LI> The cytotoxic compounds were shown as strong apoptotic inducers. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Characterization of Ag-Doped p-Type SnO Thin Films Prepared by DC Magnetron Sputtering
Pham, Hoai Phuong,Thuy, Thanh Giang Le,Tran, Quang Trung,Nguyen, Hoang Hung,My Hoa, Huynh Tran,Thi Thu, Hoang,Cuong, Tran Viet Hindawi Limited 2017 Journal of nanomaterials Vol.2017 No.-
<P>Crystalline structure and optoelectrical properties of silver-doped tin monoxide thin films with different dopant concentrations prepared by DC magnetron sputtering are investigated. The X-ray diffraction patterns reveal that the tetragonal SnO phase exhibits preferred orientations along (101) and (110) planes. Our results indicate that replacing Sn<SUP>2+</SUP> in the SnO lattice with Ag<SUP>+</SUP> ions produces smaller-sized crystallites, which may lead to enhanced carrier scattering at grain boundaries. This causes a deterioration in the carrier mobility, even though the carrier concentration improves by two orders of magnitude due to doping. In addition, the Ag-doped SnO thin films show a p-type semiconductor behavior, with a direct optical gap and decreasing transmittance with increasing Ag dopant concentration.</P>
Dieu Linh Tran,Anh Phuong Nguyen Hong,Ngoc Hoi Nguyen,Ngoc Trinh Huynh,Bao Ha Le Tran,Cam Tu Tran,Minh Dung Truong,Quan Dang Nguyen,박기동,Dai Hai Nguyen 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.120 No.-
α-calcium sulfate hemihydrate (α-HH) was synthesized by salt solution methods to prepare a promising biomaterial for bone tissue repair and regeneration. The successful synthesis of α-HH was evaluated by field emission scanning electron microscopy (FE-SEM), thermogravimetric analysis (TGA), X-ray diffraction (XRD), and Fourier transform infrared (FTIR) scanning. The sterility of α-HH before and after irradiation with gamma ray was firstly confirmed by Colonies Forming Units (CFU) counting assay, to target the surgical grade application. In vitro tetrazolium bromide (MTT) assay, crystal violet (CV) and acridine orange (AO) staining was performed to assess the initial cytotoxicity and cell attachment ability of α-HH. Further in vivo implantation into rabbit distal femoral condyles defect exhibited the ability of salt solution-synthesized α-HH to promote the localization of osteocytes and osteoblasts, which improve the bone tissue repair and regeneration. The findings suggested that α-calcium sulfate hemihydrate synthesized by salt solution method is a potential material that can be used as bone substitutes.
Examining FDI Spillover Effects on Productivity Growth: Firm-Level Evidence from Vietnam
Phuong Van Nguyen,Khoa T. Tran,Nga Thuy Thanh Le,Hoa Doan Xuan Trieu 중앙대학교 경제연구소 2020 Journal of Economic Development Vol.45 No.1
The relationship between foreign direct investment (FDI) and firm productivity still greatly concerns many researchers. Even though this topic has provided rich insight into the impacts of FDI spillovers, limited empirical research has been conducted to figure out the heterogeneous impact of such spillovers in the case of Vietnam. In this study, which employs the generalized methods of moments to investigate a sample of 537,772 enterprises operating in Vietnam in the period from 2007 to 2015, we examine how spillovers occur and how they can affect domestic firms’ productivity. Intra-industrial and regional spillovers impact negatively on the productivity of domestic firms. Regarding intra-industrial spillovers, only backward ones positively affect local productivity.
Novel antibiotic delivery using graphene oxide immobilized surfaces
( Tran Dieu Linh ),( Thai Thanh Hoang Thi ),( Phuong Le Thi ),박기동 한국공업화학회 2018 한국공업화학회 연구논문 초록집 Vol.2018 No.0
Implant-related infection is a noteworthy issue because of their negative effect to the success of implantation, and the cost of treatment. To solve this problem, the development of antimicrobial surface has been considered as an urgent mission. Herein, we demonstrated that graphene oxide (GO)-immobilized TiO<sub>2</sub> surface is an efficient carrier for the local delivery of antibiotic. The phenol-functionalized GO deriva-tive was synthesized and immobilized on TiO<sub>2</sub> under the catalysis of tyrosinase, following by the loading of doxycycline hyclate (Dox). The modified surface was able to carry 36 μg of Dox and ensured the release for a month. These surfaces also showed good antibacterial activity against both E. coli and S. aureus, without the cytotoxic effect on hDFBs. It is expected that the release of Dox from GO-immobilized surfaces can solve the pressing need for enhanced infection control
Endemic Severe Fever with Thrombocytopenia Syndrome, Vietnam
Tran, Xuan Chuong,Yun, Yeojun,Van An, Le,Kim, So-Hee,Thao, Nguyen T. Phuong,Man, Phan Kim C.,Yoo, Jeong Rae,Heo, Sang Taek,Cho, Nam-Hyuk,Lee, Keun Hwa U.S. Department of Health and Human Services * Cen 2019 Emerging Infectious Diseases Vol.25 No.5
Right lumbar lymph trunk injury after right laparoscopic donor nephrectomy: a case report
Le Thanh Dung,Le Nguyen Vu,Than Van Sy,Tran Ha Phuong,Ninh Viet Khai,Dao Xuan Hai,Nguyen Quang Nghia 대한이식학회 2023 Korean Journal of Transplantation Vol.37 No.2
Laparoscopic donor nephrectomy (LDN) is increasingly popular because of its advantages over open surgery. Chyle leak after donor nephrectomy is a rare but potentially lethal complication if not treated appropriately. We describe a case of a 43-year-old female patient with no remarkable history who presented a chyle leak on day 2 after right transperitoneal LDN. Since conservative treatment failed, the patient underwent magnetic resonance imaging (MRI) and intranodal lipiodol lymphangiography, which confirmed the chyle leak from the right lumbar lymph trunk into the right renal fossa. The chyle leak was percutaneously embolized twice, on postoperative day (POD) 5 and POD 10, by a mixture of N-butyl-2-cyanoacrylate and lipiodol. The drainage fluid decreased significantly after the second embolization. The subhepatic drainage tube was withdrawn on POD 14, and the patient was discharged on POD 17. MRI lymphangiography and intranodal lipiodol lymphangiography effectively identified the chyle leak point. Percutaneous embolization seems to be a safe, effective method for treating high-output chyle leaks.
Tran Thi Huyen,Ha Phuong Trang,Nguyen Thi-Ngan,Bui Dinh-Thanh,Le Pham Tan Quoc,Trinh Ngoc Nam 한국수산과학회 2023 Fisheries and Aquatic Sciences Vol.26 No.3
The thermolabile haemolysin (tlh) of Vibrio parahaemolyticus (Vptlh) from V. parahaemolyticus is a multiple-function enzyme, initially describes as a haemolytic factor activated by lecithin and phospholipase A2 enzymatic activity (Shinoda, 1991; Vazquez-Morado, 2021; Yanagase et al., 1970). Until now, the tlh structure has hypothesized including N-terminal and C-terminal domain, but what domain of the Vptlh structure does the haemolytic activity has not been refined yet. In this study, a 450-bp VpTLH nucleotide sequence of the entire Vptlh gene encoded the C-terminal domain cloned firstly to examine its responsibility in the activity of the Vptlh. The C-terminal domain fused with a 6-His-tag named the His-tag-VpC-terminal domain was expressed successfully in soluble form in the BL21 (DE3) PlysS cell. Remarkably, both expression and purification results confirmed a high agreement in the molecular weight of the His-tag-VpC-terminal domain was 47 kDa. This work showed the His-tag-VpC-terminal domain lysed the erythrocyte membranes in the blood agar and the phosphate buffered saline (0.9%) media without adding the lecithin substrate of the phospholipase enzyme. Haemolysis occurred at all tested diluted concentrations of His-tag-VpC-terminal domain (p < 0.05), providing evidence for the independent haemolytic activity of the His-tag-VpC-terminal domain. The content of 100 μg of the His-tag-VpC-terminal domain brought the highest haemolytic activity of 80% compared to that in the three remaining contents. Significantly, the His-tag-VpC-terminal domain demonstrated not to involve the phospholipase activity in Luria-Bertani agar supplemented with 1% (vol/vol) egg yolk emulsion. All results proved the vital responsibility of the His-tag-VpC-terminal domain in causing the haemolytic activity without the required activation by the phospholipase enzyme. Raw extracts of Phellinus igniarus and Phellinus pipi at 10–1 mg/mL inhibited the haemolytic activity of the His-tag-VpC-terminal domain from 67.7% to 87.42%, respectively. Hence applying the His-tag-VpC-terminal domain as a simple biological material to evaluate quickly potential derivatives against the Vptlh in vivo conditions will accessible and more advantageous than using the whole of the Vptlh.