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      • Mechanical properties of biodegradable coconut fibre reinforced polylactic acid composite

        Kim Yon Jig(김연직),Phan Quoc Thai(판꾹타이),Renliang Wang(왕렌리앙),Jun Yong Choi(최준용),Ruihua Hu(후루이화),Jae Kyoo Lim(임재규) 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.6

        In the recent years, the use of natural fiber as reinforcements in polymer composites for replacing synthetic fiber is rapidly increased. Coconut is growing in some tropical countries such as Vietnam, Thailand, India... especially, it is very cheap and infinite resource. Polylactic acid (PLA) is a biodegradable thermoplastic polymer, which was used extensively in recent years because the biodegradable composites are friendly with environment. This study is concerned with the mechanical properties of coconut fiber (coir) reinforced PLA composite. The coconut fiber reinforced PLA composite was manufactured by heating compression mold with different contents of coconut fiber. The tensile test and bending test will be carried out to verify the mechanical properties of composite and the effect of coconut contents to them.

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        HER2 Status and Its Heterogeneity in Gastric Carcinoma of Vietnamese Patient

        Dang Anh Thu Phan,Vu Thien Nguyen,Thi Ngoc Ha Hua,Quoc Dat Ngo,Thi Phuong Thao Doan,Sao Trung Nguyen,Anh Tu Thai,Van Thanh Nguyen 대한병리학회 2017 Journal of Pathology and Translational Medicine Vol.51 No.4

        Background: Human epidermal growth factor receptor 2 (HER2) is related to the pathogenesis and poor outcome of numerous types of carcinomas, including gastric carcinoma. Gastric cancer patients with HER2 positivity have become potential candidates for targeted therapy with trastuzumab. Methods: We investigated 208 gastric cancer specimens using immunohistochemistry (IHC), fluorescence in situ hybridization and dual in situ hybridization (ISH). We also investigated the concordance between IHC and ISH. The correlation between HER2 status and various clinicopathological findings was also investigated. Results: In total, 15.9% (33/208) and 24.5% (51/208) of gastric cancers showed HER2 gene amplification and protein overexpression, respectively. A high level of concordance between ISH and IHC analyses (91.3%, κ = 0.76) was found. A significant correlation between HER2 status and intestinal-type (p < .05) and differentiated carcinomas (p < .05) was also noted. The HER2 heterogeneity was high in gastric cancers; we found 68.8% phenotypic heterogeneity and 57.6% genotypic heterogeneity. Heterogeneity in HER2 protein expression and gene amplification showed a close association with diffuse histologic type and IHC 2+. Conclusions: HER2 protein overexpression and gene amplification were detected in 24.5% and 15.9% of gastric cancer specimens, respectively. Intestinal-type showed a higher level of HER2 protein overexpression and gene amplification than diffuse type. HER2 status also showed a significant relationship with well- and moderately-differentiated carcinomas. The ratio of phenotypic and genotypic heterogeneity of HER2 was high in gastric carcinomas and was associated with HER2 IHC 2+ and diffuse histologic type.

      • Biodegradable Composites Reinforced With Rice Husk and Rice Straw

        Renliang Wang(왕렌리앙),Jun Yong Choi(최준용),Phan Quoc Thai(판꾹타이),Sang Yong Lee(이상용),Jae-Kyoo Lim(임재규) 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.6

        In this study, rice husk and straw particles were manufactured as biodegradable composites using compression mold method. Poly-lactic Acid (PLA) a biodegradable polymer matrix is used. The raw material, rice husk and rice straw, was available and gained on the agriculture field. Chemical treatment methods were carried out on the fibers which vary the proportion of crystallinity and improve the fiber matrix adhesion. Further more, this article gives a survey about physical and mechanical properties in order to accomplish a comparison between rice husk and rice straw. The preparation and properties of the fibers are discussed briefly as well as their compatibility with existing processing technology. The effectiveness of this method is strongly influenced by the treatment conditions used. This kind of bio-composites will be used as flexural materials in construction because of the bearing capacity of pressure.

      • Fabrication and Mechanical Properties of Completely Biodegradable Hemp Fiber Reinforced PLA Composites

        Ruihua Hu,Jun Hee Song,Jun Yong Choi,Phan Quoc Thai,Jae Kyoo Lim 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.3

        A fabrication method of a kind of completely biodegradable PLA composites reinforced by short hemp fiber is developed in this paper. The fibers were treated in 6% NaOH aqueous solution and untreated respectively. In these two cases, the composites with 30%, 40% and 50% fiber volume fraction were prepared. The tensile strength, tensile modulus and flexural strength were tested. The results showed that the mechanical properties of this composite with 40% alkali treated fiber volume fraction have the highest values. They are 54.6㎫, 8.5㎬ and 112.7 ㎫ respectively. These values are competitive to those of glass fiber reinforced polypropylene. The density of this composite is 1.23g/㎝3, which is much lower than glass fiber reinforced composites with similar fiber volume fraction. The specific strength was also calculated. Fracture surfaces of the composites were observed by SEM. The results showed that there is still a potential enhancement in the properties by optimizing the fabrication condition.

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