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Α Β Γ Δ Ε Ζ Η Θ Ι Κ Λ Μ Ν Ξ Ο Π Ρ Σ Τ Υ Φ Χ Ψ Ω α β γ δ ε ζ η θ ι κ λ μ ν ξ ο π ρ σ τ υ φ χ ψ ω
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Ä Ö Ü ä ö ü ß
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‘ ’ “ ” 〔 〕 〈 〉 「 」 『 』 【 】 ＂ （ ） ［ ］ ｛ ｝
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½ ⅓ ⅔ ¼ ¾ ⅛ ⅜ ⅝ ⅞ ¹ ² ³ ⁴ ⁿ ₁ ₂ ₃ ₄
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        Preliminary Evaluation on Anti-Inflammatory and Analogesic Effects of Sideritis syriaca L. herba Extracts

        Luigi Menghini,Paola Massarelli,Giancarlo Bruni,Alessandro Menghini 한국식품영양과학회 2005 Journal of medicinal food Vol.8 No.2

        We studied the anti-inflammatory and analgesic activity of extracts ofSideritis syriacaL. herba. Samples werecollected from the wild plant, dried, powdered, and extracted with hexane and methanol. The extracts were evaporated to dry-ness and then suspended in suitable solvent. They were then tested for anti-inflammatory activity in the carrageenin rat pawedema test and for analgesic activity in the Randall and Selitto test and in the tail-flick test. At 24 hours after the treatment,the gastric mucosa of each rat was observed macroscopically. Based on these results the hexane extract was fractionated bycolumn chromatography, and the fractions were obtained tested in the same way. Results showed interesting anti-inflamma-tory activity only for the hexane extract and all the fractions obtained from it. All the extracts and all the other fractionsshowed both peripheral and central analgesic activity. In rats treated with the tested compounds hyperemia and ulcers wereabsent. The data from this preliminary study reveal interesting pharmacological properties of S. syriacaL. herbaextracts re-lated to the marked analgesic activity and the absence of gastric ulcerogenic activity. The same is for anti-inflammatory ac-tivity, but in this case it seems to be related only to the apolar fraction.

      • KCI등재후보

        Anti-Inflammatory and Analgesic Effects of Spartium junceum L. Flower Extracts: A Preliminary Study

        Luigi Menghini,Paola Massarelli,Giancarlo Bruni,Rita Pagiotti 한국식품영양과학회 2006 Journal of medicinal food Vol.9 No.3

        Our objective was to study the anti-inflammatory and analgesic activity of extract of Spartium junceumL.flowers. Samples of flowers were collected from wild plants, dried, powdered, and extracted with hexane and methanol. Theextracts were evaporated to dryness and then suspended in suitable solvent. They were then tested for anti-inflammatory ac-tivity in the carrageenin rat paw edema test and for analgesic activity in the Randall and Selitto mechanical pressure test andin the tail-flick test. Twenty-four hours after treatment, the gastric mucosa of each rat was observed macroscopically. Basedon these results the hexane extract was fractioned by column chromatography, and the fractions obtained were tested in thesame way. The results showed good anti-inflammatory activity only for a single fraction of the hexane extract, while all theextracts and all the other hexane fractions showed both peripheral and central analgesic activity. In rats treated with the testedcompounds hyperemia and ulcers were absent. The data from this preliminary study reveal interesting pharmacological prop-erties of S. junceumL. flowers extract related to the marked analgesic activity and the absence of gastric ulcerogenic activ-ity.

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