A population-based study of breast implant illness

Magno-Padron, David A.,Luo, Jessica,Jessop, Terry C.,Garlick, Jared W.,Manum, Joanna S.,Carter, Gentry C.,Agarwal, Jayant P.,Kwok, Alvin C. Korean Society of Plastic and Reconstructive Surge 2021 Archives of Plastic Surgery Vol.48 No.4

Background Despite evidence supporting the safety of breast implants, some women associate their implants with adverse health effects and have called this syndrome "breast implant illness." We sought to characterize breast implant illness symptoms and to report how implant removal affects their symptoms. Methods An anonymous 20 question survey was administered to the Facebook group: "UTAH Breast Implant Illness" to characterize the symptoms these women attributed to their breast implants. Several questions allowed us to evaluate how implant removal affected women's symptoms. Results Of the 182 respondents, 97% report that implants negatively affect their health and 95% identify these symptoms with breast implant illness. Ninety-six percent of respondents had implants placed for cosmetic reasons and 51% had silicone implants. The most common symptoms associated with breast implant illness are brain fog (95%), fatigue (92%), joint pain (80%), and hair loss (74%). Sixty percent of respondents learned about breast implant illness from family/friends and/or social media platforms (56%), 40% of respondents had their implants removed, and 97% report relief of their symptoms post-removal (23% complete, 74% partial). Following explantation, there was a significant improvement in all but one reported symptom. An association was found between the number of symptoms reported prior to explantation and the number of symptoms resolving following explantation. Conclusions Breast implant illness is a syndrome characterized by fatigue, decreased focus, hair loss, and joint pain after the placement of breast implants. Nearly all patients report improvement of symptoms after implant removal. Significant efforts should be made to better understand breast implant illness and its etiology.

Factors affecting the acceptance by Latin Americans of YouTube UGC as a travel information source about Korea: An integration of the source credibility model to the TAM

이계희,Veronica Maria Hernandez Padron,최수진 한국관광연구학회 2020 관광연구저널 Vol.34 No.4

This study seeks to shed light on YouTube users' acceptance of user-generated content (UGC). Specifically, the purpose of this study is to examine the effect of the credibility of UGC containing travel information on the viewers’ perception of the usefulness of that travel information. In addition, based on the technology acceptance model (TAM), the step-wide procedures from the perception of information to the formations of both attitude and behavioral intention to use YouTube's UGC as an information source for travel destinations in Korea among Latin Americans were tested. This study suggests a more comprehensive model by integrating the credibility source model and TAM, which may provide academics and industry with a better understanding on how the source credibility of UGC contributes to a positive attitude toward information sources and viewers’ future behavior. The results of surveying 551 Latin American YouTube users who were interested in traveling to Korea in the near future confirmed that UGC on YouTube is a credible and useful information source about travel destinations in Korea, helping to predict prospective travelers’ intention towards using UGC as an information source for Korean travel destinations. The findings hold several theoretical and managerial implications.

Developing a lodging industry competency model for the San Francisco Bay Area

Hyunsuk Choi(최현석),Saehya Ann(안세화),Thomas Padron 전북대학교 산업경제연구소 2016 아태경상저널 Vol.8 No.3

직무 역량이란 개인이 전문적 성공이나 직장의 승진 목표 달성 등을 목적으로, 개인의 직무와 그에 관련되고 필요한 기량이나 기술을 자체 관리 할 수 있는 능력을 일컫는 용어이다. 오늘날 서비스업 기업들을 직원들이 다양한 경영 능력과 운영 역량을 갖고 있거나 개발 하기를 원한다. 이는 서비스업의 본질적으로 복잡한 특성, 긴 노동 시간, 질 높은 서비스 제공에 수반되는 높은 스트레스 레벨 등에 의해 직원들이 직면하는 어려움이 다른 산업에 비하여 아주 크기 때문이다. 기존의 직무 역량에 대한 연구의 결과들이 일치점을 찾지 못하였고, 미국 샌프란시스코 지역의 호텔 산업에 대한 직무 역량 모델에 대한 연구가 제한적으로만 이루어져 왔기 때문에, 본 연구의 결과는 학생, 서비스업 교육자, 학과 프로그램 코디네이터 뿐만 아니라 산업 전문 종사자들에게도 호텔 산업이 요구하는 직무 역량에 대한 매우 유용한 정보를 제공 할 수 있을 것이라고 보여진다. Career competencies is defined as an individual’s ability to self-manage working and learning experiences in order to achieve specific career advancement goals and professional success. Today, hospitality businesses require their employees to have and develop various managerial skills and competencies, compared to what were required in the past. This is because the hospitality industry challenges the individuals more than any other industry - long working hours, and a high tolerance for stress due to the characteristics of service products. Since there has been only limited studies on a lodging industry competency model, specifically for the San Francisco Bay Area, the current study has its importance and uniqueness and the results of this study can contribute to both the academia and industry. Additionally, the previous research studies that focused on developing competency models for a lodging industry have not reached agreement when it comes to the most important competencies to train and foster future hospitality leaders. Therefore, the findings of this study will provide invaluable information for all parties that are involved such as students, hospitality educators, program coordinators, and industry professionals.

Sequential Differentiation of Human Bone Marrow Stromal Cells for Bone Regeneration

Eva Johanna Huebner,Nestor Torio Padron,David Kubosch,Guenter Finkenzeller,Norbert P. Suedkamp,Philipp Niemeyer 한국조직공학과 재생의학회 2015 조직공학과 재생의학 Vol.12 No.5

In this study we hypothesized that as a simulation of endochondral bone formation, bone marrow stromal cell (BMSC) provide a sequential chondro-osteogenic differentiation potential. A chondrogenic priming of BMSC leads to a spontaneous three-dimensional cell formation. BMSC were chondrogenically differentiated prior to an osteogenic stimulation. Duration of cell culture was 28 days, whereas in group A BMSC were chondrogenically differentiated for 1 day, followed by an osteogenic differentiation for 27 days. In group B BMSC were chondrogenically differentiated for 14 days prior to an osteogenic differentiation of 14 days and group C BMSC were differentiated chondrogenically for 28 days serving as a chondrogenic control group. Chondrogenic priming induced a spontaneous three-dimensional cell formation. To survey the stability of the osteogenic phenotype in the absence of an osteogenic stimulus, investigations were performed in vivo in a specially adapted chorioallantoic membrane model of fertilized White Leghorn eggs. Histology and real time polymerase chain reaction revealed a higher amount of osteogenic extracellular matrix synthesis and significant higher expressions of osteogenic marker genes in group B after 14 days of chondrogenic and 14 days of osteogenic stimulation. Matrix calcification in vivo in the absence of an osteogenic stimulus could be demonstrated. The results of the present study support the theory of a sequential differentiation potential of BMSC. A chondrogenic priming of BMSC stimulated into the osteogenic lineage result in a stable osteogenic phenotype in a scaffold-free, three-dimensional tissue engineering application.

Antiproliferative and antibacterial activity of extracts of Ganoderma strains grown in vitro

Leonardo Serrano-Marquez,Angel Trigos,Alan Couttolenc,Jose M. Padron,Alla V. Shnyreva,Guillermo Mendoza 한국식품과학회 2021 Food Science and Biotechnology Vol.30 No.5

In this bioprospecting study the biologicalactivities of extracts of the in vitro culture of GanodermaMexican strains were evaluated. The extracts were testedby the Sulforhodamine B staining method for antiproliferativeactivity and the plate microdilution method forantibacterial activity. Extracts that proved bioactive inthese two activities, the antioxidant activity (Galvinoxyl,ABTS, and DPPH) and total phenolic contents (Folin-Ciocalteu) were additionally determined, as well as acutetoxicity (Artemia franciscana). In the antiproliferativeactivity Ganoderma curtisii strain (GH-16-015) obtained aremarkable value of GI50 B 50 lg/mL against tumorlines: A549, HBL-100, HeLa, and T-47D. G. curtisiistrains (GH-16-012 and GH-16-015) showed MIC values= 500 lg/mL against Staphylococcus aureus. G. curtisiistrain (GH-16-012) almost reduced by 50% theradical Galvinoxyl. Finally, G. curtisii strain (GH-16-023)presented the lowest level of toxicity with a LC50 of490.881 lg/mL against A. franciscana. These resultssupport the potential medicinal effects of Mexican strainsof G. curtisii.

Design of intelligent control strategies using a magnetorheological damper for span structure

Hernandez, Angela,Marichal, Graciliano N.,Poncela, Alfonso V.,Padron, Isidro Techno-Press 2015 Smart Structures and Systems, An International Jou Vol.15 No.4

This paper focuses on the design of an intelligent control system. The used techniques are based on Neuro Fuzzy approaches applied to a magnetorheological damper in order to reduce the vibrations over footbridges; it has been applied to the Science Museum Footbridge of Valladolid, particularly. A model of the footbridge and of the damper has been built using different simulation tools, and a successful comparison with the real footbridge and the real damper has been carried out. This simulated model has allowed the reproduction of the behaviour of the footbridge and damper when a pedestrian walks across the footbridge. Once it is determined that the simulation results are similar to real data, the control system is introduced into the model. In this sense, different strategies based on Neuro Fuzzy systems have been studied. In fact, an ANFIS (Artificial Neuro Fuzzy Inference System) method has also been used, in addition to an alternative Neuro Fuzzy approach. Several trials have been carried out, using both techniques, obtaining satisfactory results after using these techniques.

Metastasis Risk Reduction Related with Beta-Blocker Treatment in Mexican Women with Breast Cancer

Parada-Huerta, E,Alvarez-Dominguez, TP,Uribe-Escamilla, R,Rodriguez-Joya, JF,Ponce-Medrano, JA Diaz,Padron-Lucio, S,Alfaro-Rodriguez, A,Bandala, C Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.6

Background: Breast Cancer (BCa) is the most common malignant tumour in Mexican women. In BCa, several studies have linked ${\beta}2-adrenergic$ receptor activation with increased tumour growth and progression as related with Epinephrine-NorEpinephrine (E-NE) stimulation. The aim of this study was to describe Beta-Blocker (BB) treatment related with reduction of the risk of metastasis in Mexican patients with BCa. Materials and Methods: We collected data of 120 patients seen at the High-Specialty Naval General Hospital in Mexico City (HOSGENAES), all of these with a histopathological diagnosis of BCa. Four groups of patients were divided as follows: without Systemic Arterial Hypertension (SAH); with SAH treatment with non-selective BB; with SAH treatment with selective BB, and with SAH treatment with other antihypertensive drugs. Chi-square, Mantel-Haenszel, Student t, and ANOVA tests were performed for data analysis. Results: On average, patients were $54.8{\pm}11.8$ years of age. Risk factors such as smoking and consuming alcohol exhibited a frequency of 33 and 36.5% respectively. Clinical stages III- IV were found in 50% of patients, while, 30% of patients had arterial hypertension (n=29 and N=96, respectively) and 17.5% used BB. One hundred percent of patients with arterial hypertension treated with BB for ${\beta}1$ - and ${\beta}2$ -adrenergic-receptors did not present metastasis globally, but patients treated with ${\beta}1$ BB presented 30% of metastasis while patients treated with no BB or without SAH had around 70% of metastasis. Conclusions: In Mexican patients with BCa and SAH treated with non-selective (${\beta}1$- and ${\beta}2-adrenergic$ receptors) BB, a decrease in the risk for metastasis was observed at the time of diagnosis.